Mechanism of the drug interaction between valproic acid and carbapenem antibiotics in monkeys and rats

Drug Metabolism and Disposition

Volumn 32, Issue 12, 2004, Pages 1383-1391

  Nakajima, Yoshitsugu ^a   Mizobuchi, Minoru ^a   Nakamura, Masahiro ^a   Takagi, Hidetoshi ^a   Inagaki, Haruhisa ^a   Kominami, Goro ^a   Koike, Masahiro ^a   Yamaguchi, Toshiro ^a  

^a SHIONOGI AND CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BETAMIPRON; CARBAPENEM; DORIPENEM; MEROPENEM; PANIPENEM; UNCLASSIFIED DRUG; VALPROIC ACID; VALPROIC ACID GLUCURONIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INTERACTION; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVITY; FEMALE; HYDROLYSIS; LIVER HOMOGENATE; LIVER MICROSOME; LIVER SLICE; MALE; MONKEY; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE;

ANIMALS; ANTICONVULSANTS; BILE; CARBAPENEMS; DRUG INTERACTIONS; FEMALE; HALF-LIFE; HYDROLYSIS; INJECTIONS, INTRAVENOUS; KIDNEY; LIVER; MACACA FASCICULARIS; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; SUBCELLULAR FRACTIONS; VALPROIC ACID;

ANIMALIA;

EID: 9444241653     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.104.000661     Document Type: Article

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