Rapid, accurate and non-invasive detection of cerebrospinal fluid leakage using combined determination of β-trace protein in secretion and serum

Clinica Chimica Acta

Volumn 351, Issue 1-2, 2005, Pages 169-176

  Risch, Lorenz ^a   Lisec, Ivan ^b   Jutzi, Markus ^b   Podvinec, Michael ^b   Landolt, Hans ^b   Huber, Andreas R ^b  

^a Hospital Saint John of God   (Austria)

^b KANTONSSPITAL   (Switzerland)

Author keywords

Trace; Cerebrospinal fluid leak; Glomerular filtration rate; Prostaglandin D synthase; Reference values; Sensitivity and specificity

Indexed keywords

BETA TRACE PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD ANALYSIS; CEREBROSPINAL FLUID; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE MARKER; FEMALE; HUMAN; LIQUORRHEA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN SECRETION; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY;

ADULT; AGED; BIOLOGICAL MARKERS; CEREBROSPINAL FLUID; CRANIOCEREBRAL TRAUMA; EAR; FEMALE; HUMANS; INTRAMOLECULAR OXIDOREDUCTASES; MALE; MIDDLE AGED; NEPHELOMETRY AND TURBIDIMETRY; NEUROSURGICAL PROCEDURES; NOSE; PROSPECTIVE STUDIES; ROC CURVE; SKULL FRACTURES; TRANSFERRIN;

EID: 9444229270     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cccn.2004.09.008     Document Type: Article

References (34)

1. G. Har-El What is "spontaneous" cerebrospinal fluid rhinorrhea? Classification of cerebrospinal fluid leaks Ann. Otol. Rhinol. Laryngol. 108 1999 323 326
2. D. Choi, and R. Spann Traumatic cerebrospinal fluid leakage: risk factors and the use of prophylactic antibiotics Br. J. Neurosurg. 10 1996 571 575
3. C. Crawford, N. Kennedy, and W.R. Weir Cerebrospinal fluid rhinorrhoea and Haemophilus influenzae meningitis 37 years after a head injury J. Infect. 28 1994 93 97
4. D.C. Lanza, D.A. O'Brian, and D.W. Kennedy Endoscopic repair of cerebrospinal fluid fistulae and encephaloceles Laryngoscope 106 1997 1119 1125
5. D.F. a Wengen, A.R. Huber, A. Regeniter, S. Wetzel, A. Haldemann, and T. Mindermann Diagnostik der Liquorrhoe bei Schadelbasislasionen Schweiz. Med. Wochenschr. 11 130 2000 1715 1725
6. A.R. Huber Zur neuen Diagnostik von Liquorfisteln HNO 48 2000 487 488
7. C. Meco, and G. Oberascher Comprehensive algorithm for skull base dural lesion and cerebrospinal fluid fistula diagnosis Laryngoscope 114 2004 991 999
8. G. Oberascher, and E. Arrer Efficiency of various methods of identifying cerebrospinal fluid in oto- and rhinorrhea ORL J. Otorhinolaryngol. Relat. Spec. 48 1986 320 325
9. D.J. Steedman CSF rhinorrhea: significance of glucose oxidase strip test Injury 18 5 1985 327 328
10. G. Oberascher, and E. Arrer First clinical experience with β-2-Transferrin in cerebrospinal fluid oto- and rhinoliquorrhea HNO 34 1986 151 155
11. D.N. Melegos, E.P. Diamandis, H. Oda, Y. Urade, and O. Hayashi Immunofluorometric assay of prostaglandin D synthase in human tissue extracts and fluids Clin. Chem. 42 1996 1984 1991
12. W.C. Freek, N. Roelandse, J.H.D. van der Zwart, J. van Loon, and J.H.M. Souverijn Detection of CSF leakage by isoelectric focusing on polyacrylamide gel, direct immunofixation of transferrins, and silver staining Clin. Chem. 44 1998 351 353
13. Y. Urade, K. Kathama, J. Oshishi, T. Kaneko, N. Mizuno, and O. Hayashi Dominant expression of m-RNA for prostaglandin D-synthetase in leptomeninges, choroids plexus and oligodendrocytes of the adult rat brain Proc. Natl. Acad. Sci. U. S. A. 90 1993 9070 9074
14. H. Reiber Dynamics of brain-derived proteins in cerebrospinal fluid Clin. Chim. Acta 20 310 2001 173 186
15. K. Felgenhauer, H.J. Schadlich, and M. Nekic β-trace protein as marker for cerebrospinal fluid fistula Klin. Wochenschr. 65 1987 764 768
16. D.M. Melegos, M.S. Freedman, and E.P. Diamandis Prostaglandin D synthase concentration in cerebrospinal fluid and serum of patients with neurological disorders Prostaglandins 54 1997 463 474
17. H. Tumani, H. Reiber, R. Nau, H.W. Prange, K. Kauffmann, and M. Mäder Felgenhauer β-trace protein concentration in cerebrospinal fluid is decreased in patients with bacterial meningitis Neurosci. Lett. 242 1998 5 8
18. T.O. Kleine, T. Damm, and H. Althaus Quantification of β-trace protein and detection of transferring isoforms in mixtures of cerebrospinal fluid and blood serum as models of rhinorrhea and otorrhea diagnosis Fresenius' J. Anal. Chem. 366 2000 382 386
19. H.F. Petereit, G. Bachmann, M. Nekic, H. Althaus, and R. Pukrop A new nephelometric assay for β-trace protein (prostaglandin D synthase) as an indicator of liquorrhoea J. Neurol. Neurosurg. Psychiatry 71 2001 347 351
20. E. Arrer, C. Meco, G. Oberascher, W. Piotrowski, K. Albegger, and W. Patsch β-trace protein as a marker for cerebrospinal rhinorrhea Clin. Chem. 48 2002 939 941
21. G. Bachmann, H. Petereit, U. Djenabi, and O. Michel Predictive values of β-trace protein (prostaglandin D synthase) by use of laser-nephelometry assay for the identification of cerebrospinal fluid Neurosurgery 50 2002 571 577
22. C. Schnabel, E. Di Martino, J.M. Gilsbach, D. Riediger, A.M. Gressner, and D. Kunz Comparison of β-2-transferrin and β-trace protein for detection of cerebrospinal fluid in nasal and ear fluids Clin. Chem. 50 2004 661 663
23. G. Bachmann, R. Achtelik, M. Nekic, and O. Michel β-trace protein in der Diagnostik der Liquorfisteln HNO 48 2000 496 500
24. G. Bachmann, M. Nekic, and O. Michel Clinical experience with beta-trace protein as a marker for cerebrospinal fluid Ann. Otol. Rhinol. Laryngol. 109 2000 1099 1102
25. C. Meco, G. Oberascher, E. Arrer, G. Moser, and K. Albegger β-trace protein test: new guidelines for the reliable diagnosis of cerebrospinal fluid fistula Otolaryngol.-Head Neck Surg. 129 2003 508 517
26. C. Meco, and G. Oberascher Comprehensive algorithm for skull base dural lesion and cerebrospinal fluid fistula diagnosis Laryngoscope 114 2004 991 999
27. H. Reiber, K. Walther, and H. Althaus Beta-trace protein as sensitive marker for CSF rhinorhea and CSF otorhea Acta Neurol. Scand. 108 2003 359 362
28. M. Mase, K. Yamada, N. Shimazu, K. Seiki, H. Oda, and H. Nakau Lipocalin-type prostaglandin D synthase (beta-trace) in cerebrospinal fluid: a useful marker for the diagnosis of normal pressure hydrocephalus Neurosci. Res. 47 2003 455 459
29. M. Mase, K. Yamada, A. Iwata, T. Matsumoto, K. Seiki, and H. Oda Acute and transient increase of lipocalin-type prostaglandin D synthase (beta-trace) level in cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage Neurosci. Lett. 270 1999 188 190
30. M.H. Zweig, and G. Campbell Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine Clin. Chem. 39 1993 561 577
31. R. Jaeschke, G.H. Guyatt, and D.L. Sackett Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group JAMA 271 1994 703 707
32. G. Filler, F. Priem, N. Lepage, P. Sinha, I. Vollmer, and H. Clark Beta-trace protein, cystatin C, beta(2)-microglobulin, and creatinine compared for detecting impaired glomerular filtration rates in children Clin. Chem. 48 2002 729 736
33. E.J. Lamb, S.E. O'Riordan, and M.P. Delaney Kidney function in older people: pathology, assessment and management Clin. Chim. Acta 334 2003 25 40
34. P. Wiesli, B. Schwegler, G.A. Spinas, and C. Schmid Serum cystatin C is sensitive to small changes in thyroid function Clin. Chim. Acta 338 2003 87 90