Effects of magnesium sulfate on Na+,K+ -ATPase and intracranial pressure level after cerebral ischemia

Magnesium Research

Volumn 17, Issue 3, 2004, Pages 169-175

  Ustun, Mehmet Erkan ^a   Bariskaner, Hulagu ^a   Yosunkaya, Alper ^a   Gurbilek, Mehmet ^a   Dogan, Necdet ^a  

^a SELCUK UNIVERSITY   (Turkey)

Author keywords

Cerebral ischemia; Magnesium sulfate; Na+ K+ ATPase; Rabbit

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BRAIN ENZYME; MAGNESIUM SULFATE; OUABAIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CLAMP; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; BRAIN SURGERY; COMMON CAROTID ARTERY; CONTROLLED STUDY; CORRELATION ANALYSIS; CRANIECTOMY; ENZYME ACTIVITY; INTRACRANIAL PRESSURE; MALE; NONHUMAN; RABBIT;

ANIMALS; BRAIN ISCHEMIA; ENZYME INHIBITORS; INTRACRANIAL HYPERTENSION; MAGNESIUM SULFATE; MALE; NA(+)-K(+)-EXCHANGING ATPASE; RABBITS;

ANIMALIA; ORYCTOLAGUS CUNICULUS; STROPHANTHUS GRATUS;

EID: 9344245749     PISSN: 09531424     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Faden AI, Demediuk P, Panter SS. The role of excitatory amino acids and NMDA receptors in traumatic head injury. Science 1989; 244: 798-800.
2. Rothman SM. The neurotoxicity of excitatory amino acids is produced by passive chloride in flux. J Neurosci 1985; 5: 1483-9.
3. Choi DW. Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci 1988; 11: 465-9.
4. Siesjo BK, Bengtsson F. Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia, and spreading depression: a unifying hypothesis. J Cereb Blood Flow Metab 1989; 9: 127-40.
5. David JT. Calcium antagonists history and perspective. Stroke 1990; 21: 49-58.
6. Shapine Y, Yadid G, Cateu S, Shohani E. Accumulation of calcium in the brain following head trauma. Neurolog Res 1989; 11: 169-71.
7. Ikeda Y, Long DM. The molecular basis of brain injury and brain edema. The role of oxygen free radicals. Neurosurgery 1990; 27: 1-11.
8. Reilly PM, Schiller HJ, Bulkley GB. Pharmacological approach to tissue injury mediated by free radicals and other reactive oxygen metabolites. Am J Surg 1991; 161: 488-503.
9. Ebel H, Gunter T. Magnesium metabolism: a review. J Clin Chem Clin Biochem 1980; 18: 257-70.
10. Rolfsen ML, Dawis WR. Cerebral function and preservation during cardiac arrest. Crit Care Med 1989; 17: 283-90.
11. Simpson JI, Eide TR, Schiff GA, Clagnaz JF, Hossain I, Tverskoy A, Koski G. Intrathecal magnesium sulfate protects the spinal cord from ischemic injury during thoracic aortic crossclamping. Anesthesiology 1994; 81: 1493-9.
12. Greenwood K, Cox P, Mehmet H, Penrice J, Amess PN, Cady EB, Wyatt JS, Edwards AD. Magnesium sulfate treatment after transient hypoxia-ischemia in the newborn piglet does not protect against cerebral damage. Pediatr Res 2000; 48(3): 346-50.
13. Penrice J, Amess PN, Punwani S, Wylezinska M, Tyszczuk L, D'Souza P, Edwards AD, Cady EB, Wyatt JS, Reynolds EO. Magnesium sulfate after transient hypoxia-ischemia fails to prevent delayed cerebral energy failure in the newborn piglet. Pediatr Res 1997; 41(3): 443-7.
14. Harik SI, Douli GH, Dick APK. Specific ouabain binding to brain microvessels and choroid plexus. J Cereb Blood Flow Metab 1985; 5: 156-60.
15. +-ATPase in cortical brain slices in normal Krebs-Ringer phosphate medium at 1 and 10 atm oxygen pressures. J Neurochem 1981; 36: 333-5.
16. Fiske CH, Subbarow Y. The calorimetric determination of phosphorus. J Biol Chem 1925; 66: 375-400.
17. Groenendaal F, Shadid M, McGowan JE, Mishra OP, vanBel F. Effects of deferoxamine a chelator of free iron on Na,K,ATPase activity of cortical brain cell membrane during early reperfusion after hypoxia-ischemia in newborn lambs. Pediatr Res 2000; 48: 560-4.
18. Ildan F, Polat S, Oner A, Isbir T, Gocer AI, Top O, Kaya M, Karadayi A. Effects of naloxone on sodium-and potassium-activated and magnesium-dependent adenosine-5-triphosphatase activity and lipid peroxidation and early ultrastructural findings after experimental spinal cord injury. Neurosurg 1995; 36: 797-805.
19. McIntosh TK, Vink R, Yamakami I, Faden AI. Magnesium protects against neurological deficit after brain injury. Brain Res 1989; 482: 252-60.
20. Zager El, Ames A. Reduction of cellular energy requirements. J Neurosurg 1988; 69: 568-79.
21. Rolfsen ML, Dawis WR. Cerebral function and preservation during cardiac arrest. Crit Care Med 1989; 17: 283-90.
22. Lehninger AL. The citric acid cycle. In: Lehninger AL (ed). The biosynthesis of lipids, Principles of biochemistry, Worth, New York, 1987; pp 435-66, pp 583-614.
23. 2+ of N-methyl-D-aspartate-activated channels. J Biophys 1990; 57: 1085-90.
24. Choi DW. Ionic dependence of glutamate neurotoxicity. J Neurosci 1987; 7: 369-79.
25. Rothman S. Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death. J Neurosci 1984; 4: 1884-91.
26. Gentile NT, McIntosh TK. Antagonists of excitatory amino acids and endogenous opioid peptides in the treatment of experimental central nervous system injury. Ann Emerg Med 1993; 22: 1028-34.
27. Shapira Y, Lam AM, Eng CC, Laohaprasit V, Michel M. Therapeutic time window and dose response of the benefical effects of ketamine in experimental head injury. Stroke 1994; 25: 1637-43.
28. Shohami E, Novikov M, Bass R. Long-term effect of HU-211 a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat. Brain Res 1995; 674: 55-62.
29. Shadid M, Moison R, Steendijk P, Hiltermann L, Berger HM, van Bel F. The effect of antioxidative combination therapy on post hypoxic-ischemic perfusion, metabolism, and electrical activity of the newborn brain. Pediatr Res 1998; 44: 119-24.
30. Sarco DP, Becker J, Palmer C, Sheldon RA, Ferriero DM. The neuroprotective effect of deferoxamine in the hypoxic-ischemic immature mouse brain. Neurosci Lett 2000; 282: 113-6.
31. Palmer C, Roberts RL, Bero C. Deferoxamine post-treatment reduces ischemic brain injury in neonatal rats. Stroke 1994; 25: 1039-45.
32. Stigson L, Kjellmer I. Serum levels of magnesium at birth related to complications of immaturity. Acta Pediatr 1997; 86: 991-4.
33. van den Bergh WM, Zuur JK, Kamerling NA, van Asseldonk JT, Rinkel GJ, Tulleken CA, Nicolay K. Role of magnesium in the reduction of ischemic depolarization and lesion volume after experimental subarachnoid hemorrhage. J Neurosurg 2002; 97: 416-22.
34. Lee EJ, Ayoub IA, Harris FB, Hassan M, Ogilvy CS, Maynard KI. Mexiletine and magnesium independently, but not combined, protect against permanent focal cerebral ischemia in Wistar rats. J Neurosci Res 1999; 58: 442-8.
35. Greenwood K, Cox P, Mehmet H, Penrice J, Amess PN, Cady EB, Wyatt JS, Edwards AD. Magnesium sulfate treatment after transient hypoxia-ischemia in the newborn piglet does not protect against cerebral damage. Pediatr Res 2000; 48: 346-50.
36. Feldman Z, Gurevitch B, Artru AA, Oppenheim A, Shohami E, Reichenthal E, Shapira Y. Effect of magnesium given 1 hour after head trauma on brain edema and neurological outcome. J Neurosurg 1996; 85: 131-7.
37. Esen F, Erdem T, Aktan D, Kalayci R, Cakar N, Kaya M, Telci L. Effects of magnesium administration on brain edema and blood brain barrier breakdown after experimental traumatic brain injury in rats. J Neurosurg Anesthesiol 2003; 15: 119-25.
38. McIntosh TK, Faden AI, Yamakami I, Vink R. Magnesium deficiency exacerbates and pretreatment improves outcome following traumatic brain injury in rats: 31P magnetic resonance spectroscopy and behavioral studies. J Neurotrauma 1988; 5: 17-31.
39. 2+ protect against irreversible damage during CNS ischemia. Stroke 1984; 15: 695-8.
40. McIntosh TK, Vink R, Yamakami I, Faden AL. Magnesium protects against neurological deficit after brain injury. Brain Res 1989; 482: 252-60.
41. Ustun ME, Gurbilek M, Ak A, Vatansev H, Duman A. Effects of magnesium sulfate on tissue lactate and malondialdehyde levels in experimental head trauma. Intensive Care Med 2001; 27: 264-8.
42. Lin JY, Chang SY, Lin MC, Cheng FC. Effects of magnesium sulfate on energy metabolites and glutamate in the cortex during focal cerebral ischemia and perfusion in the gerbil monitored by a dual-probe microdialysis technique. Life Sci 2002; 71:803-11.
43. Van Den Bergh WM, Zuur K, Kamerling NA, Van Asseldonk JTH, Rinkel GJE, Tulleken CAF, Nicolay K. Role of magnesium in the reduction of ischemic depolarization and lesion volume after experimental subarachnoid hemorrhage. J Neurosurg 2002; 97: 416-22.
44. Heath DL, Vink R. Magnesium sulphate improves neurologic outcome following severe closed head injury in rats. Neurosci Lett 1997; 228: 175-8.
45. Schmitt HJ, Barth GR, Thierauf P. Neuronal protection by intraischemic brain perfusion: an electron microscopy study in the rat. J Neurosurg Anesthesiol 1994; 6: 265-74.
46. Miles AN, Wajda BT, Meloni BP, Knuckey NW. Postischemic intravenous administration of magnesium sulfate inhibits hippocampal CA1 neuronal death after transient global ischemia in rats. Neurosurgery 2001; 49: 1443-50.
47. Marinov MB, Harbaugh KS, Hoopes PJ, Pikus HJ, Harbaugh RE. Neuroprotective effects of preischemia intraarterial magnesium sulfate in reversible focal cerebral ischemia. J Neurosurg 1996; 85: 117-24.
48. 2+ administered up to twenty-four hours following reperfusion prevents ischemic damage of the CA1 neurons in the rat hippocampus. Neuroscience 1991; 44: 335-41.
49. Yang Y, Li Q, Ahmad F, Shuaib A. Survival and histological evaluation of therapeutic window of post-ischemia treatment with magnesium sulfate in embolic stroke model of rat. Neurose Lett 2000; 285: 119-22.
50. Muir KW. New experimental and clinical data on the efficacy of pharmacological magnesium infusions in cerebral infarcts. Mag Res 1998; 11: 43-56.
51. Schmid-Elsaesser R, Zausinger S, Hungerhuber E, Baethmann A, Realen HJ. Neuroprotective effects of combination therapy with tirilazad and magnesium in rats subjected to reversible focal cerebral ischemia. Neurosurgery 1999; 44: 163-71.
52. Ustun ME, Duman A, Ogun CO, Vatansev H, Ak A. Effects of nimodipine and magnesium sulfate on endogenous antioxidant levels in brain tissue after experimental head trauma. J Neurosurg Anesthesiol 2001; 13(3): 227-32.
53. Galvin KA, Oorschot DE. Postinjury magnesium sulfate treatment is not markedly neuroprotective for striatal medium spiny neurons after perinatal hypoxia/ischemia in the rat. Pediatr Res 1998; 44: 740-5.
54. Brewer RP, Parra A, Borel CO, Hopkins MB, Reynolds JD. Intravenous magnesium sulfate does not increase ventricular CSF ionized magnesium concentration of patients with intracranial hypertension. Clin Neuropharmacol 2001; 24: 341-5.
55. Ram Z, Sadeh M, Shacked I, Sahar A, Hadani M. Magnesium sulfate reverses experimental delayed cerebral vasospasm after subarachnoid hemorrhage in rats. Stroke 1991; 22: 922-7.
56. Lees KR, Muir KW, Ford I. Magnesium for acute stroke (Intravenous Magnesium Efficacy in Stroke trial): randomised controlled trial. Lancet 2004; 363: 439-45.