QSAR analysis of 2,2-dimethyl-4,5-diarylfuran-3(2H)-ones as selective cyclooxygenase-2 inhibitors

Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry

Volumn 43, Issue 10, 2004, Pages 2249-2253

  Prasanna, S ^a   Manivannan, E ^a   Chaturvedi, S C ^b  

^a DEVI AHILYA UNIVERSITY   (India)

^b UNIVERSITY INSTITUTE OF TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2,2 DIMETHYLFURAN 3(2H) ONE DERIVATIVE; CYCLOOXYGENASE 2 INHIBITOR; FURANONE DERIVATIVE; HETEROCYCLIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; DENSITY FUNCTIONAL THEORY; HYDROPHOBICITY; LINEAR REGRESSION ANALYSIS; MOLECULAR WEIGHT; PARTITION COEFFICIENT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTUM MECHANICS; STEREOSPECIFICITY; STRUCTURE ANALYSIS;

EID: 9344227371     PISSN: 03764699     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Ajmani S & Chaturvedi S C, Eur J Med Chem, 33, 1998, 47.
2. Silakari O, Dixit A, Kohli D V & Chaturvedi S C. Indian J Pharm Sci, 63, 2001, 518.
3. Shahapurkar S, Pandya T, Kawathekar N & Chaturvedi S C. Eur J Med Chem, 39, 2004, 383.
4. Vane J R, Nature, 231, 1971, 232.
5. Shin S S, Noh M-S, Byun Y J, Choi K J, Kim J Y, Lim, K M, Ha J Y, Kim J K, Lee C H & Chung S, Bioorg Med Chem. Lett, 11, 2001, 165.
6. (a) Mitchell J A, Akarasereenont P, Thiemermann C, Flower R, J & Vane J R, Proc Natl Acad Sci, 90, 1994, 11693.
7. (b) Klein T Nusing R M Pfeilschifter J & Ullrich V Biochem Pharmacol, 48, 1994, 1605.
8. (a) Mansch C, Leo A & Hoekman D, in Exploring QSAR: Hydrophobic, Electronic and Steric Constants (ACS, Washington) 1995.
9. (b) Mansch C, Leo A, in Exploring QSAR: Fundamentals and Applications in Chemistry and Biology (ACS, Washington) 1995.
10. (c) Mansch C, Leo A, in substitution constants for correlation analysis in chemistry and biology (John Wiley & Sons, New York) 1979.
11. Verloop A, Hoogenstraaten W & Tipker J, Drug Design, Vol 7, (Ariens ed Academic Press New York), 1976, 165.
12. Roy K, Indian J Chem, 42B, 2003, 1485.
13. Connolly M, Science, 221, 1983, 709.