Quantitative structure-activity relationship analysis of a series of trans-octahydro-11-oxodibenzo-[b,e]-thiepin propionic acid derivatives

European Journal of Medicinal Chemistry

Volumn 33, Issue 1, 1998, Pages 47-53

  Ajmani, Subhash ^a   Chaturvedi, Subhash Chandra ^a  

^a SHRI G S INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

Author keywords

Antiinflammatory activity; Quantitative structure activity relationship analysis; Thiepin propionic acid esters and amides

Indexed keywords

PROPIONIC ACID DERIVATIVE;

ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COMPUTER PROGRAM; DRUG STRUCTURE; MOLECULAR MODEL; NONHUMAN; PAW EDEMA; RAT; STRUCTURE ACTIVITY RELATION;

EID: 0031940375     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)80075-0     Document Type: Article

References (23)

1. [1] Flower R.J., Moncade S., Vane J.R., in: Gilman A.G., Goodman L.S., Gilman A. (Eds.), The Pharmacological Basis of Therapeutics (6th ed.), MacMillan, New York, 1980, p. 712.
2. [2] Kurokawa M., Uno H., J. Med. Chem. 33 (1990) 504.
3. [3] Gund P., Jensen N.P., Non-Steroidal Antiinflammatory and Antiarthritic Drugs. In: Topliss J.G. (Ed.), Quantitative Structure-Activity Relationship of Drugs, Academic Press, New York, 1983, p. 285.
4. 2 version 1.6, Biosym/Molecular Simulations Inc., 9685 Scranton Road, California, USA.
5. [5] Fletcher R., Reeves C.M., Comput. J. 7 (1964) 149.
6. [6] Pearlman R.S., in: Yalkowsky S.H., Sinkula A.A., Valvani Y.C. (Eds.), Physical Chemistry Properties of Drugs, Dekker, New York, 1964.
7. [7] Hopfinger A.J., Conformational Properties of Macromolecules, Academic Press, New York, 1973.
8. [8] Leffler J.E., Grunwald E., Rates and Equilibrium Constants of Organic Reactions, Wiley, New York, 1963.
9. [9] Hansch C., Leo A., Substituent Constants for Correlation Analysis in Chemistry and Biology, Wiley, New York, 1979.
10. [10] Dunn III W.J., Eur. J. Med. Chem. 12 (1977) 109.
11. [11] Van de Waterbeemd H., Testa B., Adv. Drug. Res. 16 (1987) 85.
12. [12] James K.C., in : Smith H.J. (Ed.), Smith and Williams 'Introduction to the Principles of Drug Design', Wright, 1988, ch. 8.
13. [13] Hill T.L., Introduction to Statistical Thermodynamics, Addison Wesley, Reading, MA, 1960.
14. [14] Marsili M., Gasteiger J., Croat. Chem. Acta 53 (1980) 601.
15. [15] Bottcher C.J.F., Theory of Electric Polarization, Elsevier, Amsterdam, 1952.
16. [16] Del Re G., Biophys. Acta 15 (1963) 153.
17. [17] Gasteiger J., Marsili M., Tetrahedron Lett. 34 (1978) 3181.
18. [18] Gasteiger J., Marsili M., Tetrahedron 36 (1980) 3219.
19. [19] Pople J.A., Beveridge D.L., Approximate Molecular Orbital Theory, McGraw Hill, New York, 1970.
20. [20] Pople J.A., Segal G.A., J. Chem. Phys. 44 (1966) 3289.
21. [21] Stane A.J., Alderton M., Mol. Phys. 56 (1985) 1047.
22. [22] Williams D.E., in: Lipowitz K.B., Boyd D.B. (Eds.), Review of Computer Chemistry, VCH, New York, 1991, p. 219.
23. [23] Draper N.R., Smith H., Applied Regression Analysis, Wiley, New York, 1966.