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Volumn 45, Issue 10, 2004, Pages 1347-1360

New TAXI-type xylanase inhibitor genes are inducible by pathogens and wounding in hexaploid wheat

Author keywords

Adaptive evolution; Cell wall degrading enzyme; Cereal crops; Differential expression; Fusarium head blight (FHB); Virulence factor

Indexed keywords

ASPERGILLUS; ASPERGILLUS NIGER; BLUMERIA GRAMINIS; ERYSIPHE; ERYSIPHE GRAMINIS; FUSARIUM; FUSARIUM GRAMINEARUM; GIBBERELLA ZEAE; TRICHODERMA; TRITICUM; TRITICUM AESTIVUM; TRITICUM AESTIVUM SUBSP. SPELTA;

EID: 9244225218     PISSN: 00320781     EISSN: None     Source Type: Journal    
DOI: 10.1093/pcp/pch195     Document Type: Article
Times cited : (64)

References (50)
  • 1
    • 0032804706 scopus 로고    scopus 로고
    • TR112, a trichothecene efflux pump from Fusarium sporotrichioides: Gene isolation and expression in yeast
    • Alexander, N.J., McCormick, S.P. and Hohn, T.M. (1999) TR112, a trichothecene efflux pump from Fusarium sporotrichioides: gene isolation and expression in yeast. Mol. Gen. Genet. 261: 977-984.
    • (1999) Mol. Gen. Genet. , vol.261 , pp. 977-984
    • Alexander, N.J.1    McCormick, S.P.2    Hohn, T.M.3
  • 2
    • 0029827597 scopus 로고    scopus 로고
    • Cloning, disruption, and expression of two endo-β 1,4-xylanase genes, XYL2 and XYL3, from Cochliobolus carbonum
    • Apel-Birkhold, P.C. and Walton, J.D. (1996) Cloning, disruption, and expression of two endo-β 1,4-xylanase genes, XYL2 and XYL3, from Cochliobolus carbonum. Appl. Environ. Microbiol. 62: 4129-4135.
    • (1996) Appl. Environ. Microbiol. , vol.62 , pp. 4129-4135
    • Apel-Birkhold, P.C.1    Walton, J.D.2
  • 3
    • 0028082188 scopus 로고
    • PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1
    • Balzi, E., Wang, M., Leterme, S., Van Dyck, L. and Goffeau, A. (1994) PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1. J. Biol. Chem. 269: 2206-2214.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2206-2214
    • Balzi, E.1    Wang, M.2    Leterme, S.3    Van Dyck, L.4    Goffeau, A.5
  • 4
    • 0031025401 scopus 로고    scopus 로고
    • Structure, hormonal regulation, and chromosomal location of genes encoding barley (1→4)-β-xylan endohydrolases
    • Banik, M., Li, C.D., Langridge, P. and Fincher, G.B. (1997) Structure, hormonal regulation, and chromosomal location of genes encoding barley (1→4)-β-xylan endohydrolases. Mol. Gen. Genet. 253: 599-608.
    • (1997) Mol. Gen. Genet. , vol.253 , pp. 599-608
    • Banik, M.1    Li, C.D.2    Langridge, P.3    Fincher, G.B.4
  • 6
    • 0001136617 scopus 로고
    • Purification and properties of an endoxylanase from a corn stalk rot strain of Erwinia chrysanthemi
    • Braun, E.J. and Rodrigues, C.A. (1993) Purification and properties of an endoxylanase from a corn stalk rot strain of Erwinia chrysanthemi. Phytopathology 83: 332-338.
    • (1993) Phytopathology , vol.83 , pp. 332-338
    • Braun, E.J.1    Rodrigues, C.A.2
  • 7
    • 0002625707 scopus 로고
    • A pectin lyase inhibitor protein from cell walls of sugar beet
    • Bugbee, W.M. (1993) A pectin lyase inhibitor protein from cell walls of sugar beet. Phytopathology 83: 63-68.
    • (1993) Phytopathology , vol.83 , pp. 63-68
    • Bugbee, W.M.1
  • 8
    • 0034967035 scopus 로고    scopus 로고
    • Synthesis, processing and export of cytoplasmic endo-β-1,4-xylanase from barley aleurone during germination
    • Caspers, M.P., Lok, F., Sinjorgo, K.M., van Zeijl, M.J., Nielsen, K.A. and Cameron-Mills, V. (2001) Synthesis, processing and export of cytoplasmic endo-β-1,4-xylanase from barley aleurone during germination. Plant J. 26: 191-204.
    • (2001) Plant J. , vol.26 , pp. 191-204
    • Caspers, M.P.1    Lok, F.2    Sinjorgo, K.M.3    Van Zeijl, M.J.4    Nielsen, K.A.5    Cameron-Mills, V.6
  • 9
    • 0028541137 scopus 로고
    • cDNA cloning and nucleotide sequences of α1 and α2 thionins from hexaploid wheat endosperm
    • Castagnaro, A., Marana, C., Carbonero, P. and Garcia-Olmedo, F. (1994) cDNA cloning and nucleotide sequences of α1 and α2 thionins from hexaploid wheat endosperm. Plant Physiol. 106: 1221-1222.
    • (1994) Plant Physiol. , vol.106 , pp. 1221-1222
    • Castagnaro, A.1    Marana, C.2    Carbonero, P.3    Garcia-Olmedo, F.4
  • 11
    • 0023514138 scopus 로고
    • Differential regulation of a hydroxyproline-rich glycoprotein gene family in wounded and infected plants
    • Corbin, D.R., Sauer, N. and Lamb, C.J. (1987) Differential regulation of a hydroxyproline-rich glycoprotein gene family in wounded and infected plants. Mol. Cell. Biol. 7: 4337-4344.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 4337-4344
    • Corbin, D.R.1    Sauer, N.2    Lamb, C.J.3
  • 12
    • 0034789069 scopus 로고    scopus 로고
    • The role of polygalacturonase-inhibiting proteins (PGIPs) in defense against pathogenic fungi
    • De Lorenzo, G., D'Ovidio, R. and Cervone, F. (2001) The role of polygalacturonase-inhibiting proteins (PGIPs) in defense against pathogenic fungi. Annu. Rev. Phytopathol. 39: 313-335.
    • (2001) Annu. Rev. Phytopathol. , vol.39 , pp. 313-335
    • De Lorenzo, G.1    D'Ovidio, R.2    Cervone, F.3
  • 14
    • 0024995923 scopus 로고
    • A rapid method for the construction of synthetic genes using the polymerase chain reaction
    • Dillon, P.J. and Rosen, C.A. (1990) A rapid method for the construction of synthetic genes using the polymerase chain reaction. Biotechniques 9: 298-300.
    • (1990) Biotechniques , vol.9 , pp. 298-300
    • Dillon, P.J.1    Rosen, C.A.2
  • 15
    • 0037157113 scopus 로고    scopus 로고
    • Functional identification of the cDNA coding for a wheat endo-1,4-β-D-xylanase inhibitor
    • Elliott, G.O., Hughes, R.K., Juge, N., Kroon, P.A. and Williamson, G. (2002) Functional identification of the cDNA coding for a wheat endo-1,4-β-D-xylanase inhibitor. FEBS Lett. 519: 66-70.
    • (2002) FEBS Lett. , vol.519 , pp. 66-70
    • Elliott, G.O.1    Hughes, R.K.2    Juge, N.3    Kroon, P.A.4    Williamson, G.5
  • 17
    • 0028406286 scopus 로고
    • Triticum aestivum puroindolines, two basic cystine-rich seed proteins: cDNA sequence analysis and developmental gene expression
    • Gautier, M.F., Aleman, M.E., Guirao, A., Marion, D. and Joudrier, P. (1994) Triticum aestivum puroindolines, two basic cystine-rich seed proteins: cDNA sequence analysis and developmental gene expression. Plant Mol. Biol. 25: 43-57.
    • (1994) Plant Mol. Biol. , vol.25 , pp. 43-57
    • Gautier, M.F.1    Aleman, M.E.2    Guirao, A.3    Marion, D.4    Joudrier, P.5
  • 18
    • 0035863101 scopus 로고    scopus 로고
    • Triticum aestivum L. endoxylanase inhibitor (TAXI) consists of two inhibitors, TAXI I and TAXI II, with different specificities
    • Gebruers, K., Debyser, W., Goesaert, H., Proost, P., Van Damme, J. and Delcour, J.A. (2001) Triticum aestivum L. endoxylanase inhibitor (TAXI) consists of two inhibitors, TAXI I and TAXI II, with different specificities. Biochem. J. 353: 239-244.
    • (2001) Biochem. J. , vol.353 , pp. 239-244
    • Gebruers, K.1    Debyser, W.2    Goesaert, H.3    Proost, P.4    Van Damme, J.5    Delcour, J.A.6
  • 19
    • 0027350947 scopus 로고
    • A 61 bp enhancer element of the tobacco β-1,3-glucanase B gene interacts with one or more regulated nuclear proteins
    • Hart, C.M., Nagy, F. and Meins, F. Jr. (1993) A 61 bp enhancer element of the tobacco β-1,3-glucanase B gene interacts with one or more regulated nuclear proteins. Plant Mol. Biol. 21: 121-131.
    • (1993) Plant Mol. Biol. , vol.21 , pp. 121-131
    • Hart, C.M.1    Nagy, F.2    Meins Jr., F.3
  • 20
    • 0002855733 scopus 로고
    • Xylanases from the fungal maize pathogen Cochliobolus carbonum
    • Holden, F.R. and Walton, J.D. (1992) Xylanases from the fungal maize pathogen Cochliobolus carbonum. Physiol. Mol. Plant Pathol. 40: 39-47.
    • (1992) Physiol. Mol. Plant Pathol. , vol.40 , pp. 39-47
    • Holden, F.R.1    Walton, J.D.2
  • 21
    • 0031915374 scopus 로고    scopus 로고
    • Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101
    • Kimura, M., Kaneko, I., Komiyama, M., Takatsuki, A., Koshino, H., Yoneyama, K. and Yamaguchi, I. (1998) Trichothecene 3-O-acetyltransferase protects both the producing organism and transformed yeast from related mycotoxins. Cloning and characterization of Tri101. J. Biol. Chem. 273: 1654-1661.
    • (1998) J. Biol. Chem. , vol.273 , pp. 1654-1661
    • Kimura, M.1    Kaneko, I.2    Komiyama, M.3    Takatsuki, A.4    Koshino, H.5    Yoneyama, K.6    Yamaguchi, I.7
  • 22
    • 0036139211 scopus 로고    scopus 로고
    • MEGA2: Molecular evolutionary genetics analysis software
    • Kumar, S., Tamura, K., Jakobsen, I.B. and Nei, M. (2001) MEGA2: molecular evolutionary genetics analysis software. Bioinformatics 17: 1244-1245.
    • (2001) Bioinformatics , vol.17 , pp. 1244-1245
    • Kumar, S.1    Tamura, K.2    Jakobsen, I.B.3    Nei, M.4
  • 23
    • 0033522402 scopus 로고    scopus 로고
    • The specificity of polygalacturonase-inhibiting protein (PGIP): A single amino acid substitution in the solvent-exposed β-strand/β-turn region of the leucine-rich repeats (LRRs) confers a new recognition capability
    • Leckie, F., Mattei, B., Capodicasa, C., Hemmings, A., Nuss, L., Aracri, B., De Lorenzo, G. and Cervone, F. (1999) The specificity of polygalacturonase-inhibiting protein (PGIP): a single amino acid substitution in the solvent-exposed β-strand/β-turn region of the leucine-rich repeats (LRRs) confers a new recognition capability. EMBO J. 18: 2352-2363.
    • (1999) EMBO J. , vol.18 , pp. 2352-2363
    • Leckie, F.1    Mattei, B.2    Capodicasa, C.3    Hemmings, A.4    Nuss, L.5    Aracri, B.6    De Lorenzo, G.7    Cervone, F.8
  • 24
    • 0028949381 scopus 로고
    • Thermal asymmetric interlaced PCR: Automatable amplification and sequencing of insert end fragments from P1 and YAC clones for chromosome walking
    • Liu, Y.G. and Whitter, R.F. (1995) Thermal asymmetric interlaced PCR: automatable amplification and sequencing of insert end fragments from P1 and YAC clones for chromosome walking. Genomics 25: 674-681.
    • (1995) Genomics , vol.25 , pp. 674-681
    • Liu, Y.G.1    Whitter, R.F.2
  • 25
    • 84942782727 scopus 로고
    • Antifungal hydrolases in pea tissue. I. Purification and characterization of two chitinases and two β-1,3-glucanases differentially regulated during development and in response to fungal infection
    • Mauch, F., Hadwiger, L.A. and Boller, T. (1988) Antifungal hydrolases in pea tissue. I. Purification and characterization of two chitinases and two β-1,3-glucanases differentially regulated during development and in response to fungal infection. Plant Physiol. 87: 325-333.
    • (1988) Plant Physiol. , vol.87 , pp. 325-333
    • Mauch, F.1    Hadwiger, L.A.2    Boller, T.3
  • 27
    • 0022507362 scopus 로고
    • Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions
    • Nei, M. and Gojobori, T. (1986) Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions. Mol. Biol. Evol. 3: 418-426.
    • (1986) Mol. Biol. Evol. , vol.3 , pp. 418-426
    • Nei, M.1    Gojobori, T.2
  • 28
    • 0029240488 scopus 로고
    • Ethylene-inducible DNA binding proteins that interact with an ethylene-responsive element
    • Ohme-Takagi, M. and Shinshi, H. (1995) Ethylene-inducible DNA binding proteins that interact with an ethylene-responsive element. Plant Cell 7: 173-182.
    • (1995) Plant Cell , vol.7 , pp. 173-182
    • Ohme-Takagi, M.1    Shinshi, H.2
  • 29
    • 0030203863 scopus 로고    scopus 로고
    • TREEVIEW: An application to display phylogenetic trees on personal computers
    • Page, R.D.M. (1996) TREEVIEW: an application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 12: 357-358.
    • (1996) Comput. Appl. Biosci. , vol.12 , pp. 357-358
    • Page, R.D.M.1
  • 30
    • 0034142210 scopus 로고    scopus 로고
    • Fungal development and induction of defense response genes during early infection of wheat spikes by Fusarium graminearum
    • Pritsch, C., Muehlbauer, G.J., Bushnell, W.R., Somers, D.A. and Vance, C.P. (2000) Fungal development and induction of defense response genes during early infection of wheat spikes by Fusarium graminearum. Mol. Plant-Microb. Interact. 13: 159-169.
    • (2000) Mol. Plant-Microb. Interact. , vol.13 , pp. 159-169
    • Pritsch, C.1    Muehlbauer, G.J.2    Bushnell, W.R.3    Somers, D.A.4    Vance, C.P.5
  • 33
    • 0028446513 scopus 로고
    • Immediate early transcription activation by salicylic acid via the cauliflower mosaic virus as-I element
    • Qin, X.F., Holuigue, L., Horvath, D.M. and Chua, N.H. (1994) Immediate early transcription activation by salicylic acid via the cauliflower mosaic virus as-I element. Plant Cell 6: 863-874.
    • (1994) Plant Cell , vol.6 , pp. 863-874
    • Qin, X.F.1    Holuigue, L.2    Horvath, D.M.3    Chua, N.H.4
  • 34
    • 0035859026 scopus 로고    scopus 로고
    • Co-evolution and plant resistance to natural enemies
    • Rausher, M.D. (2001) Co-evolution and plant resistance to natural enemies. Nature 411: 857-864.
    • (2001) Nature , vol.411 , pp. 857-864
    • Rausher, M.D.1
  • 35
    • 0026210075 scopus 로고
    • Sequence of a wheat cDNA encoding a pathogen-induced thaumatin-like protein
    • Rebmann, G., Mauch, F. and Dudler, R. (1991) Sequence of a wheat cDNA encoding a pathogen-induced thaumatin-like protein. Plant Mol. Biol. 17: 283-285.
    • (1991) Plant Mol. Biol. , vol.17 , pp. 283-285
    • Rebmann, G.1    Mauch, F.2    Dudler, R.3
  • 36
  • 37
    • 0029853904 scopus 로고    scopus 로고
    • Interaction of elicitor-induced DNA-binding proteins with elicitor response elements in the promoters of parsley PR1 genes
    • Rushton, P.J., Torres, J.T., Parniske, M., Wernert, P., Hahlhrock, K. and Somssich, I.E. (1996) Interaction of elicitor-induced DNA-binding proteins with elicitor response elements in the promoters of parsley PR1 genes. EMBO J. 15: 5690-5700.
    • (1996) EMBO J. , vol.15 , pp. 5690-5700
    • Rushton, P.J.1    Torres, J.T.2    Parniske, M.3    Wernert, P.4    Hahlhrock, K.5    Somssich, I.E.6
  • 38
    • 4143057133 scopus 로고    scopus 로고
    • Structural basis for inhibition of Aspergillus niger xylanase by Triticum aestivum xylanase inhibitor-I
    • Sansen, S., De Ranter, C.J., Gebruers, K., Brijs, K., Courtin, C.M., Delcour, J.A. and Rabijns, A. (2004) Structural basis for inhibition of Aspergillus niger xylanase by Triticum aestivum xylanase inhibitor-I. J. Biol. Chem. 279: 36022-36028.
    • (2004) J. Biol. Chem. , vol.279 , pp. 36022-36028
    • Sansen, S.1    De Ranter, C.J.2    Gebruers, K.3    Brijs, K.4    Courtin, C.M.5    Delcour, J.A.6    Rabijns, A.7
  • 39
    • 0037360442 scopus 로고    scopus 로고
    • Structure and function of cereal and related higher plant (1→4)-β-xylan endohydrolases
    • Simpson, D.J., Fincher, G.B., Huang, A.H.C. and Cameron-Mills, V. (2003) Structure and function of cereal and related higher plant (1→4)-β- xylan endohydrolases. J. Cereal Sci. 37: 111-127.
    • (2003) J. Cereal Sci. , vol.37 , pp. 111-127
    • Simpson, D.J.1    Fincher, G.B.2    Huang, A.H.C.3    Cameron-Mills, V.4
  • 40
    • 0033749606 scopus 로고    scopus 로고
    • Inhibition of phenylalanine ammonialyase suppresses the resistance induced by benzothiadiazole in wheat to Blumeria graminis f. sp tritici
    • Stadnik, M.J. and Buchenauer, H. (2000) Inhibition of phenylalanine ammonialyase suppresses the resistance induced by benzothiadiazole in wheat to Blumeria graminis f. sp tritici. Physiol. Mol. Plant Pathol. 57: 25-34.
    • (2000) Physiol. Mol. Plant Pathol. , vol.57 , pp. 25-34
    • Stadnik, M.J.1    Buchenauer, H.2
  • 42
    • 0029836454 scopus 로고    scopus 로고
    • Quartet puzzling: A quartet maximum-likelihood method for reconstructing tree topologies
    • Strimmer, K. and von Haeseler, A. (1996) Quartet puzzling: a quartet maximum-likelihood method for reconstructing tree topologies. Mol. Biol. Evol. 13: 964-969.
    • (1996) Mol. Biol. Evol. , vol.13 , pp. 964-969
    • Strimmer, K.1    Von Haeseler, A.2
  • 43
    • 0036645685 scopus 로고    scopus 로고
    • A novel lactonohydrolase responsible for the detoxification of zearalenone: Enzyme purification and gene cloning
    • Takahashi-Ando, N., Kimura, M., Kakeya, H., Osada, H. and Yamaguchi, I. (2002) A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning. Biochem. J. 365: 1-6.
    • (2002) Biochem. J. , vol.365 , pp. 1-6
    • Takahashi-Ando, N.1    Kimura, M.2    Kakeya, H.3    Osada, H.4    Yamaguchi, I.5
  • 44
    • 0037373694 scopus 로고    scopus 로고
    • Analysis of expressed sequence tags from Gibberella zeae (anamorph Fusarium graminearum)
    • Trail, F., Xu, J.R., San Miguel, P., Halgren, R.G. and Kistler, H.C. (2003) Analysis of expressed sequence tags from Gibberella zeae (anamorph Fusarium graminearum). Fungal Genet. Biol. 38: 187-197.
    • (2003) Fungal Genet. Biol. , vol.38 , pp. 187-197
    • Trail, F.1    Xu, J.R.2    San Miguel, P.3    Halgren, R.G.4    Kistler, H.C.5
  • 45
    • 0028431863 scopus 로고
    • Developmental, hormonal, and pathogenesis-related regulation of the tobacco class I β-1,3-glucanase B promoter
    • Vögeli-Lange, R., Fründt, C., Hart, C.M., Nagy, F. and Meins, F., Jr. (1994) Developmental, hormonal, and pathogenesis-related regulation of the tobacco class I β-1,3-glucanase B promoter. Plant Mol. Biol. 25: 299-311.
    • (1994) Plant Mol. Biol. , vol.25 , pp. 299-311
    • Vögeli-Lange, R.1    Fründt, C.2    Hart, C.M.3    Nagy, F.4    Meins Jr., F.5
  • 46
    • 0028007674 scopus 로고
    • Deconstructing the cell wall
    • Walton, J.D. (1994) Deconstructing the cell wall. Plant Physiol. 104: 1113-1118.
    • (1994) Plant Physiol. , vol.104 , pp. 1113-1118
    • Walton, J.D.1
  • 47
    • 0032076826 scopus 로고    scopus 로고
    • Xa2ID encodes a receptor-like molecule with a leucine-rich repeat domain that determines race-specific recognition and is subject to adaptive evolution
    • Wang, G.L., Ruan, D.L., Song, W.Y., Sideris, S., Chen, L., Pi, L.Y., Zhang, S., Zhang, Z., Fauquet, C., Gaut, B.S., Whalen, M.C. and Ronald, P.C. (1998) Xa2ID encodes a receptor-like molecule with a leucine-rich repeat domain that determines race-specific recognition and is subject to adaptive evolution. Plant Cell 10: 765-779.
    • (1998) Plant Cell , vol.10 , pp. 765-779
    • Wang, G.L.1    Ruan, D.L.2    Song, W.Y.3    Sideris, S.4    Chen, L.5    Pi, L.Y.6    Zhang, S.7    Zhang, Z.8    Fauquet, C.9    Gaut, B.S.10    Whalen, M.C.11    Ronald, P.C.12
  • 48
    • 0030878885 scopus 로고    scopus 로고
    • Deletion of two endo-β-1,4-xylanase genes reveals additional isozymes secreted by the rice blast fungus
    • Wu, S.C., Ham, K.S., Darvill, A.G. and Albersheim, P. (1997) Deletion of two endo-β-1,4-xylanase genes reveals additional isozymes secreted by the rice blast fungus. Mol. Plant-Microbe Interact. 10: 700-708.
    • (1997) Mol. Plant-Microbe Interact. , vol.10 , pp. 700-708
    • Wu, S.C.1    Ham, K.S.2    Darvill, A.G.3    Albersheim, P.4
  • 49
    • 0037073809 scopus 로고    scopus 로고
    • Maize tapetum xylanase is synthesized as a precursor, processed and activated by a serine protease, and deposited on the pollen
    • Wu, S.S., Suen, D.F., Chang, H.C. and Huang, A.H. (2002) Maize tapetum xylanase is synthesized as a precursor, processed and activated by a serine protease, and deposited on the pollen. J. Biol. Chem. 277: 49055-49064.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49055-49064
    • Wu, S.S.1    Suen, D.F.2    Chang, H.C.3    Huang, A.H.4
  • 50
    • 0029856175 scopus 로고    scopus 로고
    • Isolation and characterization of a tobacco mosaic virus-inducible myb oncogene homolog from tobacco
    • Yang, Y. and Klessig, D.F. (1996) Isolation and characterization of a tobacco mosaic virus-inducible myb oncogene homolog from tobacco. Proc. Natl Acad. Sci. USA 93: 14972-14977.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 14972-14977
    • Yang, Y.1    Klessig, D.F.2


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