The pharmacokinetic inter-relationship of tiagabine in blood, cerebrospinal fluid and brain extracellular fluid (frontal cortex and hippocampus)

Seizure

Volumn 13, Issue 8, 2004, Pages 574-581

  Wang, Xiaolan ^a   Ratnaraj, Neville ^a   Patsalos, Philip N ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Blood; Cerebrospinal fluid; Extracellular fluid; Frontal cortex; Hippocampus; Pharmacokinetics; Tiagabine

Indexed keywords

TIAGABINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; BRAIN REGION; CEREBROSPINAL FLUID ANALYSIS; CISTERNA MAGNA; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG PENETRATION; DRUG PROTEIN BINDING; EXTRACELLULAR FLUID; FRONTAL CORTEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; JUGULAR VEIN; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; VEIN CATHETERIZATION;

ANIMALS; ANTICONVULSANTS; EPILEPSY; EXTRACELLULAR FLUID; FRONTAL LOBE; HIPPOCAMPUS; MALE; MICRODIALYSIS; NIPECOTIC ACIDS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 9244220183     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seizure.2004.01.007     Document Type: Article

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