Expression of the chondromodulin-I gene in chondrosarcomas

Cancer Letters

Volumn 204, Issue 1, 2004, Pages 61-68

  Aoyama, Tomoki ^a,b   Okamoto, Takeshi ^a,b   Nagayama, Satoshi ^a,b   Nishijo, Koichi ^a,b   Ishibe, Tatsuya ^a,b   Yasura, Ko ^a,b   Tsuboyama, Tadao ^b   Nakayama, Tomitaka ^b   Nakashima, Yasuaki ^b   Nakamura, Takashi ^b   Toguchida, Junya ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Chondromodulin I; Chondrosarcoma; Enchondroma; Osteochondroma

Indexed keywords

CHONDROMODULIN I; PARATHYROID HORMONE RELATED PROTEIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; CANCER GRADING; CANCER RECURRENCE; CARCINOGENESIS; CARTILAGE CELL; CARTILAGE TUMOR; CHONDROSARCOMA; CONTROLLED STUDY; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR GENE;

EID: 9144267711     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2003.09.015     Document Type: Article

References (19)

1. Hiraki Y., Tanaka H., Inoue H., Kondo J., Kamizono A., Suzuki F. Molecular cloning of a new class of cartilage-specific matrix, chondromodulin-I, which stimulates growth of cultured chondrocytes. Biochem. Biophys. Res. Commun. 175:1991;971-977.
2. Hiraki Y., Inoue H., Iyama K., Kamizono A., Ochiai M., Shukunami C., Iijima S., Suzuki F. Identification of chondromodulin I as a novel endothelial cell growth inhibitor. J. Biol. Chem. 272:1997;32419-32426.
3. Shukunami C., Hiraki Y. Expression of cartilage-specific functional matrix chondromodulin-1 mRNA in rabbit growth plate chondrocytes and its responsiveness to growth stimuli in vitro. Biochem. Biophys. Res. Commun. 249:1998;885-890.
4. Hiraki Y., Mitsui K., Endo N., Takahashi K., Hayami T., Inoue H., et al. Molecular cloning of human chondromodulin-I, a cartilage-derived growth modulating factor, and its expression in Chinese hamster ovary cells. Eur. J. Biochem. 260:1999;869-878.
5. Shukunami C., Hiraki Y. Role of cartilage-derived anti-angiogenic factor, chondromodulin-I during endochondral bone formation. Osteoarthritis Cartilage. 9:2001;S91-S101.
6. Brandau O., Aszodi A., Hunziker E.B., Neame P.J., Vestweber D., Fässler R. Chondromodulin I is dispensable during enchondral ossification and eye development. Mol. Cell. Biol. 22:2002;6627-6635.
7. Nakamichi Y., Shukunami C., Yamada T., Aihara K., Kawano H., Sato T., et al. Chondromodulin I is a bone remodeling factor. Mol. Cell. Biol. 23:2003;636-644.
8. Hayami T., Shukunami C., Mitsui K., Endo N., Tokunaga K., Kondo J., et al. Specific loss of chondromodulin-I gene expression in chondrosarcoma and the suppression of tumor angiogenesis and growth by its recombinant protein in vivo. Fed. Eur. Biochem. Soc. Lett. 458:1999;436-440.
9. Huvos A.G. Bone Tumors. 2nd ed. 1991;Saunders Co. Philadelphia.
10. Unni K.K. Dahlin's bone tumors. General aspects and data on 11,807 cases. 5th ed. 1996;Lippincott-Raven, Philadelphia.
11. Dorfman H.D., Czerniak B. Bone Tumors. 1998;Mosby, St Louis.
12. Springfield D.S., Gebhardt M.C., McGuire M.H. Chondrosarcoma: a review. J. Bone Joint Surg. 78A:1996;141-149.
13. Sugimura A., Sato T., Hirabayashi T., Kanda H., Kitagawa T., Kawaguchi N., Imamura T., Machinami R. Possible association of p53 overexpression and mutation with high-grade chondrosarcoma. Dign. Mol. Pathol. 2:1993;257-263.
14. Yamaguchi T., Toguchida J., Wadayama B., Kanoe H., Nakayama T., Ishizaki K., et al. Loss of heterozygosity and tumor suppressor gene mutations in chondrosarcoma. Anticancer Res. 16:1996;2009-2016.
15. Asp J., Sangiorgi L., Inerot S.E., Lindahl A., Molendini L., Benassi M.S., Picci P. Changes of the p16 gene but not the p53 gene in human chondrosarcoma tissues. Int. J. Cancer. 85:2000;3042-3048.
16. Hackel C.G., Krueger S., Grote H.J., Oshiro Y., Hodges S., Johnston D.A., et al. Overexpression of cathepsin B and urokinase plasminogen activator is associated with increased risk of recurrence and metastasis in patients with chondrosarcoma. Cancer. 89:2000;995-1003.
17. Sulzbacher I., Birner P., Trieb K., Muhlbauer M., Lang S., Chott A. Platelet-derived growth factor-alpha receptor expression supports the growth of conventional chondrosarcoma and is associated with adverse outcome. Am. J. Surg. Pathol. 25:2001;1520-1527.
18. Aoyama T., Nagayama S., Okamoto T., Hosaka T., Nakamata T., Nishijo K., et al. Mutation analyses of the NFAT1 gene in chondrosarcomas and enchondromas. Cancer Lett. 186:2002;49-57.
19. Bovee J.V.M.G., van den Broek L.J.C.M., Cleton-Jansen A.-M., Hogendoorn P.C. Up-regulation of PTHrP and bcl-2 expression characterizes the progression of osteochondroma towards peripheral chondrosarcoma and is a late event in central chondrosarcoma. Lab. Invest. 80:2000;1925-1934.