-
1
-
-
0036390209
-
Direct costs of severe sepsis in three German intensive care units based on retrospective electronic patient record analysis of resource use
-
Moerer O, Schmid A, Hofmann M, Herklotz A, Reinhart K, Werdan K, Schneider H, Burchardi H (2002) Direct costs of severe sepsis in three German intensive care units based on retrospective electronic patient record analysis of resource use. Intensive Care Med 28(10):1440-1446
-
(2002)
Intensive Care Med
, vol.28
, Issue.10
, pp. 1440-1446
-
-
Moerer, O.1
Schmid, A.2
Hofmann, M.3
Herklotz, A.4
Reinhart, K.5
Werdan, K.6
Schneider, H.7
Burchardi, H.8
-
2
-
-
0028784689
-
Multiple organ dysfunction score: A reliable descriptor of a complex clinical outcome
-
Marshall JC, Cook DJ, Christou NV, Bernard GR, Sprung CL, Sibbald WJ (1995) Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med 23(10):1638-1652
-
(1995)
Crit Care Med
, vol.23
, Issue.10
, pp. 1638-1652
-
-
Marshall, J.C.1
Cook, D.J.2
Christou, N.V.3
Bernard, G.R.4
Sprung, C.L.5
Sibbald, W.J.6
-
3
-
-
3042793210
-
Akutes Leberversagen. Aktuelle Aspekte zur Diagnostik und Therapie
-
Bauer M, Paxian M, Kortgen A (2004) Akutes Leberversagen. Aktuelle Aspekte zur Diagnostik und Therapie. Anaesthesist 53:511-530
-
(2004)
Anaesthesist
, vol.53
, pp. 511-530
-
-
Bauer, M.1
Paxian, M.2
Kortgen, A.3
-
4
-
-
0022442847
-
Is intensive care worth it? An assessment of input and outcome for the critically ill
-
Sage WM, Rosenthal MH, Silverman JF (1986) Is intensive care worth it? An assessment of input and outcome for the critically ill. Crit Care Med 14(9):777-782
-
(1986)
Crit Care Med
, vol.14
, Issue.9
, pp. 777-782
-
-
Sage, W.M.1
Rosenthal, M.H.2
Silverman, J.F.3
-
5
-
-
0038482456
-
Such stuff as dreams are made of: Mediator-directed therapy in sepsis
-
Marshall JC (2003) Such stuff as dreams are made of: mediator-directed therapy in sepsis. Nat Rev Drug Discov 2(5):391-405
-
(2003)
Nat Rev Drug Discov
, vol.2
, Issue.5
, pp. 391-405
-
-
Marshall, J.C.1
-
6
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard GR, Vincent JL, Laterre PF, LaRosa SP, Dhainaut JF, Lopez-Rodriguez A, Steingrub JS, Garber GE, Helterbrand JD, Ely EW, Fisher CJ Jr (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344(10): 699-709
-
(2001)
N Engl J Med
, vol.344
, Issue.10
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
LaRosa, S.P.4
Dhainaut, J.F.5
Lopez-Rodriguez, A.6
Steingrub, J.S.7
Garber, G.E.8
Helterbrand, J.D.9
Ely, E.W.10
Fisher Jr., C.J.11
-
7
-
-
0036255482
-
Markers of endothelial damage in organ dysfunction and sepsis
-
Reinhart K, Bayer O, Brunkhorst F, Meisner M (2002) Markers of endothelial damage in organ dysfunction and sepsis. Crit Care Med 30(5 Suppl):S302-312
-
(2002)
Crit Care Med
, vol.30
, Issue.5 SUPPL.
-
-
Reinhart, K.1
Bayer, O.2
Brunkhorst, F.3
Meisner, M.4
-
8
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M; Early Goal-Directed Therapy Collaborative Group (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345(19): 1368-1377
-
(2001)
N Engl J Med
, vol.345
, Issue.19
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
Ressler, J.4
Muzzin, A.5
Knoblich, B.6
Peterson, E.7
Tomlanovich, M.8
-
9
-
-
0003684486
-
Molecular biology of multiple organ dysfunction syndrome: Injury, adaptation, and apoptosis
-
Cobb JP, Buchman TG, Karl IE, Hotchkiss RS (2000) Molecular biology of multiple organ dysfunction syndrome: injury, adaptation, and apoptosis. Surg Infect (Larchmt) 1(3): 207-215
-
(2000)
Surg Infect (Larchmt)
, vol.1
, Issue.3
, pp. 207-215
-
-
Cobb, J.P.1
Buchman, T.G.2
Karl, I.E.3
Hotchkiss, R.S.4
-
10
-
-
0037711138
-
Recovery of hepatocellular ATP and "pericentral apoptosis" after hemorrhage and resuscitation
-
Paxian M, Bauer I, Rensing H, Jaeschke H, Mautes AE, Kolb SA, Wolf B, Stockhausen A, Jeblick S, Bauer M (2003) Recovery of hepatocellular ATP and "pericentral apoptosis" after hemorrhage and resuscitation. FASEB J 17(9):993-1002
-
(2003)
FASEB J
, vol.17
, Issue.9
, pp. 993-1002
-
-
Paxian, M.1
Bauer, I.2
Rensing, H.3
Jaeschke, H.4
Mautes, A.E.5
Kolb, S.A.6
Wolf, B.7
Stockhausen, A.8
Jeblick, S.9
Bauer, M.10
-
11
-
-
0030324314
-
Involvement of bacteria/endotoxin translocation in the development of multiple organ failure
-
Bahrami S, Redl H, Yao YM, Schlag G (1996) Involvement of bacteria/endotoxin translocation in the development of multiple organ failure. Curr Top Microbiol Immunol 216:239-258
-
(1996)
Curr Top Microbiol Immunol
, vol.216
, pp. 239-258
-
-
Bahrami, S.1
Redl, H.2
Yao, Y.M.3
Schlag, G.4
-
13
-
-
0029015753
-
The acute-phase response
-
Pannen BH, Robotham JL (1995) The acute-phase response. New Horiz 3(2):183-197
-
(1995)
New Horiz
, vol.3
, Issue.2
, pp. 183-197
-
-
Pannen, B.H.1
Robotham, J.L.2
-
14
-
-
0029903114
-
Sir Isaac Newton, sepsis, SIRS, and CARS
-
Bone RC (1996) Sir Isaac Newton, sepsis, SIRS, and CARS. Grit Care Med 24:1125-1128
-
(1996)
Grit Care Med
, vol.24
, pp. 1125-1128
-
-
Bone, R.C.1
-
15
-
-
0141920370
-
Bench-to-bedside review: Microvascular dysfunction in sepsis-hemodynamics, oxygen transport, and nitric oxide
-
Bateman RM, Sharpe MD, Ellis CG (2003) Bench-to-bedside review: microvascular dysfunction in sepsis-hemodynamics, oxygen transport, and nitric oxide. Crit Care 7(5):359-373
-
(2003)
Crit Care
, vol.7
, Issue.5
, pp. 359-373
-
-
Bateman, R.M.1
Sharpe, M.D.2
Ellis, C.G.3
-
16
-
-
0036894517
-
Endothelin-1 and heme oxygenase-1 as modulators of sinusoidal tone in the stress-exposed rat liver
-
Rensing H, Bauer I, Zhang JX, Paxian M, Pannen BH, Yokoyama Y, Clemens MG, Bauer M (2002) Endothelin-1 and heme oxygenase-1 as modulators of sinusoidal tone in the stress-exposed rat liver. Hepatology 36(6): 1453-1465
-
(2002)
Hepatology
, vol.36
, Issue.6
, pp. 1453-1465
-
-
Rensing, H.1
Bauer, I.2
Zhang, J.X.3
Paxian, M.4
Pannen, B.H.5
Yokoyama, Y.6
Clemens, M.G.7
Bauer, M.8
-
17
-
-
0034835936
-
Nitric oxide synthase inhibition as therapy for sepsis: A decade of promise
-
discussion 100-101
-
Cobb JP (2001) Nitric oxide synthase inhibition as therapy for sepsis: a decade of promise. Surg Infect (Larchmt) 2(2):93-100 (discussion 100-101)
-
(2001)
Surg Infect (Larchmt)
, vol.2
, Issue.2
, pp. 93-100
-
-
Cobb, J.P.1
-
18
-
-
1242337462
-
New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology
-
Levi M, de Jonge E, van der Poll T (2004) New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology. Ann Med 36(1):41-49
-
(2004)
Ann Med
, vol.36
, Issue.1
, pp. 41-49
-
-
Levi, M.1
De Jonge, E.2
Van Der Poll, T.3
-
19
-
-
0032741946
-
Disseminated intravascular coagulation: Clinical spectrum and established as well as new diagnostic approaches
-
Müller-Berghaus G, ten Gate H, Levi M (1999) Disseminated intravascular coagulation: clinical spectrum and established as well as new diagnostic approaches. Thromb Haemost 82(2): 706-712
-
(1999)
Thromb Haemost
, vol.82
, Issue.2
, pp. 706-712
-
-
Müller-Berghaus, G.1
Ten Gate, H.2
Levi, M.3
-
20
-
-
0034922431
-
Tissue factor pathway inhibitor activity in severe sepsis
-
Creasey AA, Reinhart K (2001) Tissue factor pathway inhibitor activity in severe sepsis. Crit Care Med 29(Suppl 7):S126-129
-
(2001)
Crit Care Med
, vol.29
, Issue.7 SUPPL.
-
-
Creasey, A.A.1
Reinhart, K.2
-
21
-
-
0029912586
-
Role of tissue factor and factor VIIa in the coagulant and inflammatory response to LD100 Escherichia coli in the baboon
-
Taylor FB Jr (1996) Role of tissue factor and factor VIIa in the coagulant and inflammatory response to LD100 Escherichia coli in the baboon. Haemostasis 26(Suppl 1):83-91
-
(1996)
Haemostasis
, vol.26
, Issue.1 SUPPL.
, pp. 83-91
-
-
Taylor Jr., F.B.1
-
22
-
-
0038690407
-
Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: A randomized controlled trial
-
Abraham E, Reinhart K, Opal S, Demeyer I, Doig C, Rodriguez AL, Beale R, Svoboda P, Laterre PF, Simon S, Light B, Spapen H, Stone J, Seibert A, Peckelsen C, De Deyne C, Postier R, Pettila V, Artigas A, Percell SR, Shu V, Zwingelstein C, Tobias J, Poole L, Stolzenbach JC, Creasey AA; OPTIMIST Trial Study Group (2003) Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA 290(2):238-247
-
(2003)
JAMA
, vol.290
, Issue.2
, pp. 238-247
-
-
Abraham, E.1
Reinhart, K.2
Opal, S.3
Demeyer, I.4
Doig, C.5
Rodriguez, A.L.6
Beale, R.7
Svoboda, P.8
Laterre, P.F.9
Simon, S.10
Light, B.11
Spapen, H.12
Stone, J.13
Seibert, A.14
Peckelsen, C.15
De Deyne, C.16
Postier, R.17
Pettila, V.18
Artigas, A.19
Percell, S.R.20
Shu, V.21
Zwingelstein, C.22
Tobias, J.23
Poole, L.24
Stolzenbach, J.C.25
Creasey, A.A.26
more..
-
23
-
-
2542451293
-
Comparison of mechanisms after post-hoc analyses of the drotrecogin alfa (activated) and antithrombin III trials in severe sepsis
-
Wiedermann CJ, Kaneider NC (2004) Comparison of mechanisms after post-hoc analyses of the drotrecogin alfa (activated) and antithrombin III trials in severe sepsis. Ann Med 36(3):194-203
-
(2004)
Ann Med
, vol.36
, Issue.3
, pp. 194-203
-
-
Wiedermann, C.J.1
Kaneider, N.C.2
-
24
-
-
1942439753
-
Crosstalk between inflammation and thrombosis
-
Esmon CT (2004) Crosstalk between inflammation and thrombosis. Maturitas 47(4):305-314
-
(2004)
Maturitas
, vol.47
, Issue.4
, pp. 305-314
-
-
Esmon, C.T.1
-
25
-
-
0027169430
-
The gastrointestinal tract. The "undrained abscess" of multiple organ failure
-
Marshall JC, Christou NV, Meakins JL (1993) The gastrointestinal tract. The "undrained abscess" of multiple organ failure. Ann Surg 218(2):111-119
-
(1993)
Ann Surg
, vol.218
, Issue.2
, pp. 111-119
-
-
Marshall, J.C.1
Christou, N.V.2
Meakins, J.L.3
-
26
-
-
0037108543
-
Influence of combined intravenous and topical antibiotic prophylaxis on the incidence of infections, organ dysfunctions, and mortality in critically ill surgical patients: A prospective, stratified, randomized, double-blind, placebo-controlled clinical trial
-
Krueger WA, Lenhart FP, Neeser G, Ruckdeschel G, Schreckhase H, Eissner HJ, Forst H, Eckart J, Peter K, Unertl KE (2002) Influence of combined intravenous and topical antibiotic prophylaxis on the incidence of infections, organ dysfunctions, and mortality in critically ill surgical patients: a prospective, stratified, randomized, double-blind, placebo-controlled clinical trial. Am J Respir Crit Care Med 166(8):1029-1037
-
(2002)
Am J Respir Crit Care Med
, vol.166
, Issue.8
, pp. 1029-1037
-
-
Krueger, W.A.1
Lenhart, F.P.2
Neeser, G.3
Ruckdeschel, G.4
Schreckhase, H.5
Eissner, H.J.6
Forst, H.7
Eckart, J.8
Peter, K.9
Unertl, K.E.10
-
27
-
-
0035829852
-
Intensive insulin therapy in the critically ill patients
-
Van den Berghe G, Wouters P, Weekers F, Verwaest C, Bruyninckx F, Schetz M, Vlasselaers D, Ferdinande P, Lauwers P, Bouillon R (2001) Intensive insulin therapy in the critically ill patients. N Engl J Med 345(19):1359-1367
-
(2001)
N Engl J Med
, vol.345
, Issue.19
, pp. 1359-1367
-
-
Van Den Berghe, G.1
Wouters, P.2
Weekers, F.3
Verwaest, C.4
Bruyninckx, F.5
Schetz, M.6
Vlasselaers, D.7
Ferdinande, P.8
Lauwers, P.9
Bouillon, R.10
-
28
-
-
0036187359
-
Beneficial effects of short-term vasopressin infusion during severe septic shock
-
Patel BM, Chittock DR, Russell JA, Walley KR (2002) Beneficial effects of short-term vasopressin infusion during severe septic shock. Anesthesiology 96(3):576-582
-
(2002)
Anesthesiology
, vol.96
, Issue.3
, pp. 576-582
-
-
Patel, B.M.1
Chittock, D.R.2
Russell, J.A.3
Walley, K.R.4
-
29
-
-
0345107246
-
High-dose vasopressin is not superior to norepinephrine in septic shock
-
Klinzing S, Simon M, Reinhart K, Bredle DL, Meier-Hellmann A (2003) High-dose vasopressin is not superior to norepinephrine in septic shock. Crit Care Med 31(11):2646-2650
-
(2003)
Crit Care Med
, vol.31
, Issue.11
, pp. 2646-2650
-
-
Klinzing, S.1
Simon, M.2
Reinhart, K.3
Bredle, D.L.4
Meier-Hellmann, A.5
-
30
-
-
0036972302
-
Reducing mortality in sepsis: New directions
-
Vincent JL, Abraham E, Annane D, Bernard G, Rivers E, Van den Berghe G (2002) Reducing mortality in sepsis: new directions. Crit Care 6(Suppl 3):S1-18
-
(2002)
Crit Care
, vol.6
, Issue.3 SUPPL.
-
-
Vincent, J.L.1
Abraham, E.2
Annane, D.3
Bernard, G.4
Rivers, E.5
Van Den Berghe, G.6
-
31
-
-
0037151571
-
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
-
Annane D, Sebille V, Charpentier C, Bollaert PE, Francois B, Korach JM, Capellier G, Cohen Y, Azoulay E, Troche G, Chaumet-Riffaut P, Bellissant E (2002) Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 288(7):862-871
-
(2002)
JAMA
, vol.288
, Issue.7
, pp. 862-871
-
-
Annane, D.1
Sebille, V.2
Charpentier, C.3
Bollaert, P.E.4
Francois, B.5
Korach, J.M.6
Capellier, G.7
Cohen, Y.8
Azoulay, E.9
Troche, G.10
Chaumet-Riffaut, P.11
Bellissant, E.12
-
32
-
-
0035421655
-
Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis
-
Harbarth S, Holeckova K, Froidevaux C, Pittet D, Ricou B, Grau GE, Vadas L, Pugin J; Geneva Sepsis Network (2001) Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 164(3):396-402
-
(2001)
Am J Respir Crit Care Med
, vol.164
, Issue.3
, pp. 396-402
-
-
Harbarth, S.1
Holeckova, K.2
Froidevaux, C.3
Pittet, D.4
Ricou, B.5
Grau, G.E.6
Vadas, L.7
Pugin, J.8
-
33
-
-
0032734656
-
Discrimination of infectious causes of early acute respiratory distress syndrome by procalcitonin
-
Brunkhorst FM, Eberhard OK, Brunkhorst R (1999) Discrimination of infectious causes of early acute respiratory distress syndrome by procalcitonin. Crit Care Med 27(10): 2172-2176
-
(1999)
Crit Care Med
, vol.27
, Issue.10
, pp. 2172-2176
-
-
Brunkhorst, F.M.1
Eberhard, O.K.2
Brunkhorst, R.3
-
35
-
-
0036433328
-
Prognostic value of the indocyanine green plasma disappearance rate in critically ill patients
-
Sakka SG, Reinhart K, Meier-Hellmann A (2002) Prognostic value of the indocyanine green plasma disappearance rate in critically ill patients. Chest 122(5):1715-1720
-
(2002)
Chest
, vol.122
, Issue.5
, pp. 1715-1720
-
-
Sakka, S.G.1
Reinhart, K.2
Meier-Hellmann, A.3
-
36
-
-
0036905885
-
The Multiple Organ Dysfunction Score (MODS) versus the Sequential Organ Failure Assessment (SOFA) score in outcome prediction
-
Peres Bota D, Melot C, Lopes Ferreira F, Nguyen Ba V, Vincent JL (2002) The Multiple Organ Dysfunction Score (MODS) versus the Sequential Organ Failure Assessment (SOFA) score in outcome prediction. Intensive Care Med 28(11):1619-1624
-
(2002)
Intensive Care Med
, vol.28
, Issue.11
, pp. 1619-1624
-
-
Peres Bota, D.1
Melot, C.2
Lopes Ferreira, F.3
Nguyen Ba, V.4
Vincent, J.L.5
-
37
-
-
0030015661
-
The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure
-
On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine
-
Vincent JL, Moreno R, Takala J, Willatts S, De Mendonca A, Bruining H, Reinhart CK, Suter PM, Thijs LG (1996) The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med 22(7):707-710
-
(1996)
Intensive Care Med
, vol.22
, Issue.7
, pp. 707-710
-
-
Vincent, J.L.1
Moreno, R.2
Takala, J.3
Willatts, S.4
De Mendonca, A.5
Bruining, H.6
Reinhart, C.K.7
Suter, P.M.8
Thijs, L.G.9
|