Involvement of bacteria/endotoxin translocation in the development of multiple organ failure

Current Topics in Microbiology and Immunology

Volumn 216, Issue , 1996, Pages 238-258

  Bahrami, S ^a   Redl, H ^a   Yao, Y M ^a   Schlag, G ^a  

^a LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; BACTERICIDAL PERMEABILITY INCREASING PROTEIN; BACTERIUM LIPOPOLYSACCHARIDE; CYTOKINE; ENDOTOXIN; EPIDERMAL GROWTH FACTOR; GLUTAMINE; INTERLEUKIN 6; MONOCLONAL ANTIBODY; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; POLYMYXIN B; RECOMBINANT PROTEIN; SOMATOMEDIN C; THROMBOCYTE ACTIVATING FACTOR ANTAGONIST; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ANTIBODY;

BACTEREMIA; BACTERIAL TRANSLOCATION; BURN; DIGESTIVE SYSTEM; DISINFECTION; ENDOTOXEMIA; HUMAN; HYPOVOLEMIA; INJURY; MULTIPLE ORGAN FAILURE; NONHUMAN; PRIORITY JOURNAL; REVIEW;

ANIMALS; BACTEREMIA; BACTERIAL PHYSIOLOGY; BURNS; ENDOTOXINS; HUMANS; LIPOPOLYSACCHARIDES; MOVEMENT; MULTIPLE ORGAN FAILURE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030324314     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-80186-0_11     Document Type: Article

References (111)

1. Alexander JW (1993) Prevention of bacterial translocation with early enterai feeding - a feasible approach? In Faist E, Meakins J, Schildberg FW (eds) Host defense dysfunction in trauma, shock and sepsis: mechanisms and therapeutic approaches Springer, Berlin, Heidelberg New York, pp 903-909
2. Alexander JW, Boyce ST, Babcock GF, Gianotti L, Peck MD, Dunn DL, Pyles T, Childress CP, Ash SK (1990) The process of microbial translocation Ann Surg 212: 496-510
3. Alexander JW, Gianotti L, Pyles T, Carey MA, Babcock GF (1991) Distribution and survival of Escherichia coli translocating from the intestine after thermal injury Ann Surg 213: 558-566
4. Ayala A, Perrin MM, Meldrum DR, Ertel W, Chaudry IH (1990) Hemorrhage induces an increase in serum TNF which is not associated with elevated levels of endotoxins. Cytokine 2: 170-174
5. Ayala A, Wang P, Ba ZF, Perrin MM, Ertel W, Chaudry IH (1991) Differential alterations in plasma IL-6 and TNF levels after trauma and hemorrhage Am J Physiol 260: R167-R171
6. Bahrami S, Yao YM, Leichtfried G, Redl H, Schlag G, Foulkes R (1994) Efficacy of monoclonal antibody (mab) to tumor necrosis factor (TNF) against hemorrhage-induced mortality in rats Intensive Care Med 20: S61
7. Bahrami S, Schlag G, Yao YM, Redl H (1995a) Significance of translocation/endotoxin in the development of systemic sepsis following trauma and/or hemorrhage. In: Levin J, Alving CR, Munford RS et al. (eds) Bacterial endotoxins lipopolysaccharides from genes to therapy John Wiley, New York, 197-208
8. Bahrami S, Schlag G, Yao YM, Redl H (1995b) Involvement of endotoxin, tumour necrosis factor, and nitric oxide in haemorrhagic shock-related alterations. In: Schlag G, Redl H (eds) Shock, sepsis, and organ failure - nitric oxide. Springer, Berlin Heidelberg New York, pp 59-76 (Fourth Wiggers Bernard Conference 1994)
9. Baker JW, Deitch EA, Li M, Berg RD, Specian RD (1988) Hemorrhage shock induces bacterial translocation from the gut. J Trauma 28: 896-906
10. Baue AE (1975) Multiple, progressive, or sequential systems failure: a syndrome of the 1970's. Arch Surg 110 779-781
11. Bertok L (1977) Physico-chemical defense of vertebrate organisms: the role of bile acids in defense against bacterial endotoxins. Perspect Biol Med 21: 70-76
12. Brathwaite CEM, Ross SE, Nagele R, Mure JA, O'Malley KF, Garcia-Perez FA (1993) Bacterial translocation occurs in humans after traumatic injury: evidence using immunofluorescence. J Trauma 34: 586-589
13. Burke DJ, Alverdy JC, Aoys E, Moss GS (1989) Glutamine-supplemented total parenteral nutrition improves gut immune function. Arch Surg 124: 1396-1399
14. Cabie A, Farkas JC, Fitting C, Laurian C, Cormier JM, Carlet J, Cavaillon JM (1993) High levels of portal TNF-a during abdominal aortic surgery in man. Cytokine 5: 448-453
15. Cahill CJ, Pain JA, Bailey ME (1987) Bile salts, endotoxin and renal function in obstructive jaundice Surg Gynecol Obstet 165: 519-522
16. Carrico CJ, Meakins JL, Marshall JC, Fry D, Maier RV (1986) Multiple-organ-failure syndrome. Arch Surg 121: 196-208
17. Carter EA, Tompkins RG, Schiffrin E, Burke JF (1990) Cutaneous thermal injury alters macromolecular permeability of rat small intestine Surgery 107: 335-341
18. Caty MG, Guice KS, Oldham KT, Remick DG, Kunkel SI (1990) Evidence for tumor necrosis factor-induced pulmonary microvascular injury after intestinal ischemia-reperfusion injury. Ann Surg 212. 694-700
19. Chaudry IH, Ayala A (1993) Mechanism of increased susceptibility to infection following hemorrhage Am J Surg 165: 59S-67S
20. Chaudry IH, Ertel W, Ayala A (1993) Alterations in inflammatory cytokine production following hemorrhage and resuscitation. In: Schlag G, Redl H, Traber DL (eds) Cytokine network Springer, Berlin Heidelberg New York, pp 72-127 (Third Wiggers Bernard Conference)
21. Cruz N, Lu Q, Berg R, Deitch EA (1994) The Caco-2 cell monolayer system as an in vitro model for studying bacterial-enterocyte interactions and bacterial translocation J Burn Care Rehabil 15. 207-212
22. Culbertson WR, Elstun W, Cole W, Altemeier WA (1959) Bacterial studies in irreversible hemorrhagic shock Arch Surg 79: 185-189
23. Deitch EA (1989) Simple intestinal obstruction causes bacterial translocation in man. Arch Surg 124: 699-701
24. Deitch EA (1990a) Intestinal permeabilities increased in burn patients shortly after injuries. Surgery 107, 411-416
25. Deitch EA (1990b) The role of intestinal barrier failure and bacterial translocation in the development of systemic infection and multiple organ failure. Arch Surg 125: 403-404
26. Deitch EA, Berg RD (1987a) Endotoxin but not malnutrition promotes bacterial translocation of the gut flora in burned mice. J Trauma 27: 161-166
27. Deitch EA, Berg RD (1987b) Bacterial translocation from the gut: a mechanism of infection. J Burn Care Rehabil 8 475-482
28. Deitch EA, Bridges RM (1987) Effects of stress and trauma on bacterial translocation from the gut. J Surg Res 42. 536-542
29. Deitch EA, Maejima K, Berg R (1985) Effect of oral antibiotics and bacterial overgrowth on the translocation of the Gl tract microflora in burned rats. J Trauma 25: 385-392
30. Deitch EA, Baker T, Berg R. Ma L (1987a) Hemorrhagic shock promotes the systemic translocation of bacteria from the gut J Trauma 27: 815
31. Deitch EA, Berg R, Specian R (1987b) Endotoxin promotes the translocation of bacteria from the gut Arch Surg 122: 185-190
32. Deitch EA, Winterton J, Berg R (1987c) Effect of starvation, malnutrition, and trauma on the gastrointestinal tract flora and bacterial translocation. Arch Surg 122: 1019-1024
33. Deitch EA, Winterton J, Li M, Berg R (1987d) The gut as a portal of entry for bacteremia Role of protein malnutrition. Ann Surg 205: 681-692
34. Deitch EA, Bridges W, Baker J, Ma JW, Ma L, Grisham MB, Granger DN, Specian RD, Berg R (1988) Hemorrhagic shock-induced bacterial translocation is reduced by xanthine oxidase inhibition or inactivation Surgery 104 191-198
35. Deitch EA, Ma L, Ma WJ, Grisham MB, Granger DN, Specian RD, Berg RD (1989) Inhibition of endotoxin-induced bacterial translocation in mice J Clin Invest 84: 36-42
36. Deitch EA, Specian RD, Berg RD (1991) Endotoxin-induced bacterial translocation and mucosal permeability: role of xanthine oxidase, complement activation, and macrophage products. Crit Care Med 19. 785-791
37. Deitch EA, Dazhong X, Franko L, Ayala A, Chaudry IH (1994) Evidence favoring the role of the gut as a cytokine-generating organ in rats subjected to hemorrhagic shock. Shock 1: 141-146
38. Di Padova FE, Brade H, Barclay GR, Poxton IR, Liehl E, Schuetze E, Kocher HP, Ramsay G, Schreier MH, McClelland DB et al. (1993) A broadly cross-protective monoclonal antibody binding to Escherichia coli and Salmonella lipopolysaccharides Infect Immun 61: 3863-3872
39. Dijkstra HM, Manson WL, Klasen HJ, Van der Waaij D (1992) Effect of polymyxin B on intestinal bacterial translocation in Pseudomonas aeruginosa wound-colonized burned mice. Eur Surg Res 24: 69-76
40. Dobke MK, Simoni J, Ninnemann JL, Garrett J, Harnar TJ (1989) Endotoxemia after burn injury: effect of early excision on circulating endotoxin levels J Burn Care Rehabil 10. 107-111
41. Donohoe MK, Rush BFJ, Koziol JM, Machiedo GW (1986) Role of antibiotics in late survival from hemorrhagic shock. Surg Forum 27. 62-64
42. Endo S, Inada K, Kikuchi M, Yamada Y, Kasoi T, Kondo M, Hoshi S, Yamashita H, Suzuki M, Yoshida M (1992) Are plasma endotoxin levels related to burn size and prognosis? Burns 18 486-489
43. Ertel W, Morrison MH, Ayala A, Chaudry IH (1991a) Chloroquine attenuates hemorrhagic shock-induced suppression of Kupffer cell antigen presentation and major histocompatibility complex class II antigen expression through blockade of tumor necrosis factor and prostaglandin release Blood 78: 1781-1788
44. Ertel W, Morrison MH, Ayala A, Perrin MM, Chaudry IH (1991b) Anti-TNF monoclonal antibodies prevent hemorrhage-induced suppression of Kupffer cell antigen presentation and MHC class II antigen expression Immunology 74: 290-297
45. Faist E, Baue AE, Dittmer H, Heberer G (1983) multiple organ failure in polytrauma patients J Trauma 23: 775-787
46. Fine J, Frank E, Rutenburg S, Schweinberg F (1959) The bacterial factor in traumatic shock. N Engl J Med 260: 214-220
47. Foulkes R, Hughes B, Kingaby R, Woodger R, Vetterlein O (1994) Anti-TNF treatment reduces severity of organ damage in a concious rabbit model of hemorrhagic/traumatic shock Intensive Care Med 20: 72
48. Fry DE, Pearlstein L, Fulton RL, Polk HC (1980) Multiple system organ failure: the role of uncontrolled infection. Arch Surg 115: 136-140
49. Gans H, Matsumoto K (1974) The escape of endotoxin from the intestine Surg Gynecol Obstet 139 395-402
50. Garidis DT, Ischigama M, Woodruff PW, Fine J (1973) Role of intestinal flora in clearance and detoxification of circulating endotoxin J Reticulo endothel Soc 14: 513-521
51. Garrison RN, Fry DE, Berberich S, Polk HC (1982) Enterococcal bacteremia: clinical implications and determinants of death. Ann Surg 196: 43-47
52. Goris RJ, te Boekhorst TP, Nuytinck JK, Gimbrere JS (1985) Multiple-organ failure Generalized autodestructive inflammation? Arch Surg 120: 1109-1115
53. Haglund U (1993) Hypoxic damage. In. Schlag G, Redl H (eds) Pathophysiology of shock, sepsis, and organ failure Springer, Berlin Heidelberg New York, pp 314-321
54. Hammond JM, Potgieter PD, Saunders GL, Forder AA (1992) Double-blind study of selective decontamination of the digestive tract in intensive care [see comments]. Lancet 340: 5-9
55. Haskel y, Dazhong X, Lu Q, Deitch EA (1994) Bombesin protects against bacterial translocation induced by three commercially available liquid enteral diets: a prospective, randomized, multigroup trial. Crit Care Med 22: 108-113
56. Jiang JX, Bahrami S, Leichtfried G, Redl H, Oehlinger W, Schlag G (1995) Kinetics of endotoxin and tumor necrosis factor appearance in portal and systemic circulation following hemorrhagic shock in rats. Ann Surg 221 100-106
57. Jones WG, Minei JP, Barber AE et al. (1990a) Angiotensin converting enzyme inhibitor decreases bacterial translocation after burn injury. FASEB 9. A953
58. Jones WG, Minei JP, Barber AE, Rayburn JL, Fahey TJ, Shires GT, Shires GT (1990b) Bacterial translocation and intestinal atrophy after thermal injury and burn wound sepsis. Ann Surg 211: 399-405
59. Koziol JM, Rush BF Jr, Smith SM, Machiedo GW (1988) Occurrence of bacteremia during and after hemorrhagic shock J Trauma 28: 10-16
60. Liehr H, Englisch G, Rasenack U (1980) Lactulose-a drug with anti-endotoxin effect Hepatogastroenterology 27. 356-360
61. Machnicki M, Zimecki M, Zagulski T (1993) Lactoferrin regulates the release of tumor necrosis factor alpha and interleukin 6 in vivo. Int J Exp Pathol 74: 433-439
62. Maejima K, Deitch EA, Berg RD (1984) Bacterial translocation from the gastrointestinal tracts of rats receiving thermal injury Infect Immun 43: 6-10
63. Marshall JC, Christou NV, Meakins JL (1993) The gastrointestinal tract. The "undrained abscess" of multiple organ failure [see comments]. Ann Surg 218: 111-119
64. Marzi I, Bauer M, Secci A, Bahrami S, Redl H, Schlag G (1995) Effect of anti-tumor necrosis factor-alpha on lekocyte adhesion in the liver after hemorrhagic shock: an intravital microscopy study in the rat. Shock 3: 27-33
65. Marzi M, Bauer M, Reisdorf E, Bahrami S, Redl H, Buehren V (1993) TNFa and PAF modulate leukocyte adhesion in the liver after hemorrhagic shock in vivo. Circ Shock Suppl 1: 23
66. Moore F, Poggetti R, McAnena O, Peterson V, Abernathy C, Parsons P (1991) Gut bacterial translocation via the portal vein: a clinical perspective with major torso trauma. J Trauma 31. 629-638
67. Morris SE, Navaratnam N, Herndon DN (1990) A Comparison of effects of thermal injury and smoke inhalation on bacterial translocation J Trauma 30: 639-643
68. Munster AM, Smith Meek M, Dickerson C, Winchurch RA (1993) Translocation. Incidental phenomenon or true pathology? Ann Surg 218: 321-326
69. Navaratnam N, Morris SE, Townsend MC, Traber DL, Traber LD, Herndon DN (1989) Bacterial translocation and selective mesenteric artery perfusion with nitroprusside in an ovine model. Int J Radiat Oncol Biol Phys 21: 240
70. Nitsche D, Schulz C, Nebermann L (1993) Prevention of gut-derived endotoxemia by means of oral administration of lactorferrin Circ Shock Suppl 1: 47-48
71. Payne D, Kubes P (1993) Nitric oxide donors reduce the rise in reperfusion-induced intestinal mucosal permeability Am J Physiol 265: 189-195
72. Peitzman A, Udekwu A, Ochoa J, Smith S (1991) Bacterial translocation in trauma patients. J Trauma 31. 1083-1087
73. Petros A, Bennett D, Vallance P (1991) Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock [see comments] Lancet 338: 1557-1558
74. Plaut AG, Goorbach SL, Nahas L, Weinstein L, Spauknebel G, Levitan R (1967) Studies of intestinal microflora. III the microbial flora of intestinal mucosa in fluids Gastroenterology 53. 868-873
75. Polk HC, Shields CL (1973) Remote organ failure, a valid sign of occult intra-abdominal infection. Surgery 81: 310-313
76. Redl H, Schlag G, Dinges HP, Bahrami S, Buurman WA, Schade U, Ceska M (1991) Trauma and sepsis induced activation of granulocytes, monocytes/macrophages and endothelial cells in primates In: Schlag G, Redl H, Siegel JH et al. (eds) Shock, sepsis, and organ failure Springer, Berlin Heidelberg New York, pp 297-313 (Second Wiggers Bernard Conference)
77. Rhee P, Waxman K, Clark L, Kaupke CJ, Vaziri ND, Tominaga G, Scannell G (1993) Tumor necrosis factor and monocytes are released during hemorrhagic shock. Resuscitation 25: 249-255
78. Roumen RM, Hendriks T, Wevers RA, Goris JA (1993) Intestinal permeability after severe trauma and hemorrhagic shock is increased without relation to septic complications. Arch Surg 128: 453-457
79. Rush BFJ (1989) Irreversibility in hemorrhagic shock is caused by sepsis. Ann Surg 55: 204-208
80. Rush BFJ, Sori AJ, Murphy TF, Smith S, Flanagan JJ, Machiedo GW (1988) Endotoxemia and bacteremia during hemorrhagic shock, the link between trauma and sepsis? Ann Surg 207: 549-554
81. Rush BFJ, Redan JA, Flanagan JJ, Heneghan JB, Hsieh J, Murphy TF, Smith S, Machiedo GW (1989) Does the bacteremia observed in hemorrhagic shock have clinical significance? A study in germfree animals Ann Surg 210. 342-347
82. Ryan CM, Yarmush ML, Burke JF, Tompkins RG (1992) Increased gut permeability early after burns correlates with the extent of burn injury. Crit Care Med 20: 1508-1512
83. Sanderson PJ (1989) Selective decontamination of the digestive tract Br Med J 299: 1413-1414
84. Savage DC (1978) Factors involved in the colonization of the gut epithelial surface. Am J Clin Nutr 31: 131-135
85. Scannell G, Waxman K, Kaml GJ, Ioli G, Gatanaga T, Yamamoto R, Granger GA (1993) Hypoxia induces a human macrophage cell line to release tumor necrosis factor-alpha and its soluble receptors in vitro. J Surg Res 54: 281-285
86. Schlag G, Redl H, Dinges HP, Radmore K (1991) Bacterial translocation in a baboon model of hypovolemic-traumatic shock In. Schlag G, Redl H, Siegel JH et al. (eds) shock, sepsis and organ failure. Springer, Berlin Heidelberg New York, pp 53-90 (Second Wiggers Bernard Conference)
87. Schlag G, Redl H, Bahrami S, Davies J, Smuts P, Marzi I (1993a) Trauma and cytokines. In Schlag G, Redl H, Traber DL (eds) Shock, sepsis organ failure Springer, Berlin Heidelberg New York pp 128-155
88. Schlag G, Redl H, Khakpour Z, Davies J, Pretorius J (1993b) Hypovolemic-traumatic shock models in baboons. In: Schlag G, Redl H (eds) Pathophysiology of shock, sepsis, and organ failure. Springer, Berlin Heidelberg New York pp 384-402
89. Sheng ZY, Yang HM (1994) The concept and the diagnosis of multiple systems organ failure Chin Med J 107: 563-569
90. Shenkar R, Abraham E (1993) Effects of hemorrhage on cytokine gene transcription Lymphokine Cytokine Res 12: 237-247
91. Spaeth G, Specian RD, Berg RD, Deitch EA (1990) Food without fiber promotes bacterial translocation from the gut. Surgery 108: 240-247
92. Stoutenbeek CP, Saene van HKF, Miranda DR et al (1984) The effect of selective contamination of the digestive tract on colonization and infection rate in multiple trauma patients. Intensive Care Med 10: 185-192
93. Stylianos S, Wakabayashi G, Gelfand JA, Harris BH (1991) Experimental hemorrhage and blunt trauma do not increase circulating tumor necrosis factor. J Trauma 31: 1063-1067
94. Thiemermann C, Szabo C, Mitchell JA, Vane JR (1993) Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide. Proc Natl Acad Sci USA 90. 267-271
95. Tokyay R, Traber DL, Herndon DN (1990) Thromboxane synthese inhibition prevents the increased mesenteric vascular resistance seen after major thermal injury in a chronic porcine model. Surg Forum 41: 56-59
96. Tomasi TB (1983) Mechanisms of immune regulation at mucosal surfaces. Rev Infect Dis 5 Suppl 4: S784-S792
97. Topping DL, Illman RJ (1986) Bacterial fermentation in the human large bowel. Time to change from the roughage model of dietary fibre? Med J Aust 144: 307-309
98. Van Leeuwen PAM, Hong RW, Rounds JD, Roderick ML, Wilmore D (1991) Hepatic failure and coma after liver resection is reversed by manipulation of gut contents: the role of endotoxin. Surgery 110: 169-175
99. Wilmore DW, Smith RJ, O'Dwyer ST, Jacobs DO, Ziegler TR, Wang XD (1988) The gut: a central organ after surgical stress Surgery 104: 917-923
100. Winchurch RA, Thupari JN, Munster AM (1987) Endotoxemia in burn patients, levels of circulating endotoxins are related to burn size Surgery 102: 808-812
101. Wolochow H, Hildebrand GJ, Lammanna C (1966) Translocation of microorganisms across the intestinal wall in rats: effect of microbial size and concentration. J Infect Dis 116. 523-528
102. Yao Y, Tian H, Sheng Z, Wang Y, Shi Z, Lan F (1992a) The role of endotoxin in the pathogenesis of experimental multiple system organ failure a preliminary report Chin Med Sci J 7: 161-165
103. Yao Y, Tian H, Wang Y, Sheng Z, Xu S (1992b) Protective effect of re-LPS antiserum on experimental multiple system organ failure. Chin Med J 105: 833-838
104. Yao YM, Yu Y, Wang YP, Lu LR, Tian HM, Sheng ZY (1994) Selective decontamination of the digestive tract (SDD) prevents bacterial/endotoxin translocation and mortality in thermal-injured rats. In: Mutz NJ, Koller W, Benzer H (eds) 7th European congress on intensive care medicine Monduzzi, Bologna, pp 1097-1102
105. Yao YM, Bahrami S, Leichtfried G, Redl H, Schiag G (1995a) Effects of NG-monomethyl-L-arginine (L-NMMA) on hemodynamics and mortality in rats following hemorrhagic shock. Shock 3 Suppl: 71
106. 21) Ann Surg 221: 398-405
107. Yao YM, Sheng ZY, Tian HM, Yu Y, Wang YP, Yang HM, Guo ZR, Gao WY (1995c) The association of circulating endotoxemia with the development of multiple organ failure in burned patients Burns (in press)
108. Zapata Sirvent RL, Hansbrough JF, Wolf P, Grayson LS, Nicolson M (1993) Epidermal growth factor limits structural alterations in gastronintestinal tissues and decreases bacterial translocation in burned mice. Surgery 113. 564-573
109. Zeigler ST, Traber DL, Herndon D (1993) Bacterial translocation in burns. In: Schlag G, Redl H (eds) Pathophysiology of shock, sepsis, and organ failure. Springer, Berlin Heidelberg New York, pp 300-313
110. Ziegler TR, Smith RJ, O'Dwyer ST, Demling RH, Wilmore DW (1988) increased intestinal permeability associated with infection in burn patients Arch Surg 123 1313-1319
111. Zingarelli B, Squadrito F, Altavilla D, Calapai G, Di Rosa M, Caputi Ap (1994) Role of tumor necrosis factor-a in acute hypovolemic hemorrhagic shock in rats. Am J Physiol 266: H1512-H1515