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Volumn 5, Issue 5, 2003, Pages 679-691

Increased exercise ejection fraction and reversed remodeling after long-term treatment with metoprolol in congestive heart failure: A randomized, stratified, double-blind, placebo-controlled trial in mild to moderate heart failure due to ischemic or idiopathic dilated cardiomyopathy

Author keywords

Cardiomyopathy; Drugs; Exercise; Heart failure; Ischemia

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIGOXIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; METOPROLOL; PLACEBO; RADIOISOTOPE;

EID: 9144264195     PISSN: 13889842     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1388-9842(03)00105-3     Document Type: Article
Times cited : (75)

References (43)
  • 1
    • 0023902318 scopus 로고
    • Treatment of patients with symptomless left ventricular dysfunction after myocardial infarction
    • Sharpe N, Murphy J, Smith H, Hannan S. Treatment of patients with symptomless left ventricular dysfunction after myocardial infarction. Lancet 1988;1:255-9.
    • (1988) Lancet , vol.1 , pp. 255-259
    • Sharpe, N.1    Murphy, J.2    Smith, H.3    Hannan, S.4
  • 2
    • 0028127720 scopus 로고
    • Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effect of captopril
    • For the SAVE Investigators
    • Sutton M, St J, Pfeffer MA, Plappert T, Rouleau J-L, Moyé LA, et al. For the SAVE Investigators. Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effect of captopril. Circulation 1994;89:68-75.
    • (1994) Circulation , vol.89 , pp. 68-75
    • Sutton, M.1    St, J.2    Pfeffer, M.A.3    Plappert, T.4    Rouleau, J.-L.5    Moyé, L.A.6
  • 3
    • 0033514046 scopus 로고    scopus 로고
    • The cardiac insufficiency bisoprolol study II (CIBIS-II): A randomized trial
    • CIBIS-II Investigators and Committees. The cardiac insufficiency bisoprolol study II (CIBIS-II): a randomized trial. Lancet 1999;353:9-13.
    • (1999) Lancet , vol.353 , pp. 9-13
  • 4
    • 0033549290 scopus 로고    scopus 로고
    • Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF)
    • MERIT-HF Study Group. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999;353:2001-2007.
    • (1999) Lancet , vol.353 , pp. 2001-2007
  • 5
    • 0037159310 scopus 로고    scopus 로고
    • Effect of carvedilol on the morbidity of patients with severe chronic heart failure: Results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study
    • 22 October
    • Packer M, Fowler MB, Roecker EB, Coats AJ, Katus HA, Krum H, et al. Effect of carvedilol on the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized cumulative survival (COPERNICUS) study. Circulation 22 October, 2002;106(17):2194-9.
    • (2002) Circulation , vol.106 , Issue.17 , pp. 2194-2199
    • Packer, M.1    Fowler, M.B.2    Roecker, E.B.3    Coats, A.J.4    Katus, H.A.5    Krum, H.6
  • 6
    • 0024430518 scopus 로고
    • Long-term beta blockade in dilated cardiomyopathy. Effects of short-and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol
    • Waagstein F, Caidahl K, Wallentin I, Bergh CH, Hjalmarson Å. Long-term beta blockade in dilated cardiomyopathy. Effects of short-and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol. Circulation 1989;80:551-63.
    • (1989) Circulation , vol.80 , pp. 551-563
    • Waagstein, F.1    Caidahl, K.2    Wallentin, I.3    Bergh, C.H.4    Hjalmarson, Å.5
  • 7
    • 0029006613 scopus 로고
    • Effect of carvedilol, a vasodilator-beta-blocker, in patients with congestive heart failure due to ischemic heart disease
    • Australia-New Zealand Heart Failure Research Collaborative Group. Effect of carvedilol, a vasodilator-beta-blocker, in patients with congestive heart failure due to ischemic heart disease. Circulation 1995;92:212-8.
    • (1995) Circulation , vol.92 , pp. 212-218
  • 8
    • 0030997947 scopus 로고    scopus 로고
    • Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease
    • Doughty RN, Whalley GA, Gamble G, MacMahon S, Sharpe N. Left ventricular remodeling with carvedilol in patients with congestive heart failure due to ischemic heart disease. Am Coll Cardiol 1997;29:1060-6.
    • (1997) Am Coll Cardiol , vol.29 , pp. 1060-1066
    • Doughty, R.N.1    Whalley, G.A.2    Gamble, G.3    MacMahon, S.4    Sharpe, N.5
  • 9
    • 0027135308 scopus 로고
    • Beneficial effects of the metoprolol in idiopathic dilated cardiomyopathy (MDC) trial. A randomised, double-blind, placebo-controlled multicentre trial
    • Waagstein F, Bristow MR, Swedberg K. Beneficial effects of the metoprolol in idiopathic dilated cardiomyopathy (MDC) trial. A randomised, double-blind, placebo-controlled multicentre trial. Lancet 1993;342:1441-6.
    • (1993) Lancet , vol.342 , pp. 1441-1446
    • Waagstein, F.1    Bristow, M.R.2    Swedberg, K.3
  • 10
    • 0028951035 scopus 로고
    • Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade
    • Hall SA, Cigarroa CG, Marcoux L, Risser RC, Grayburn PA, Eichhorn EJ. Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade. J Am Coll Cardiol 1995;25:1154-61.
    • (1995) J Am Coll Cardiol , vol.25 , pp. 1154-1161
    • Hall, S.A.1    Cigarroa, C.G.2    Marcoux, L.3    Risser, R.C.4    Grayburn, P.A.5    Eichhorn, E.J.6
  • 12
    • 0032958134 scopus 로고    scopus 로고
    • Carvedilol prevents remodeling in patients with left ventricular dysfunction after acute myocardial infarction
    • Senior R, Basu S, Kinsey C, Schaeffer S, Lahiri A. Carvedilol prevents remodeling in patients with left ventricular dysfunction after acute myocardial infarction. Am Heart J 1999;137:646-52.
    • (1999) Am Heart J , vol.137 , pp. 646-652
    • Senior, R.1    Basu, S.2    Kinsey, C.3    Schaeffer, S.4    Lahiri, A.5
  • 13
    • 0034816963 scopus 로고    scopus 로고
    • Regression of left ventricular remodeling in chronic heart failure: Comparative and combined effects of captopril and carvedilol
    • Khattar RS, Senior R, Soman R, van der Does R, Lahiri A. Regression of left ventricular remodeling in chronic heart failure: Comparative and combined effects of captopril and carvedilol. Am Heart J;142:704-713.
    • Am Heart J , vol.142 , pp. 704-713
    • Khattar, R.S.1    Senior, R.2    Soman, R.3    Van Der Does, R.4    Lahiri, A.5
  • 15
    • 18744425643 scopus 로고    scopus 로고
    • Effects of bisoprolol fumarate on left ventricular size, function and exercise capacity in patients with heart failure: Analysis with magnetic resonance myocardial tagging
    • Dubach P, Myers J, Bonetti P, Schertler T, Froelicher V, Wagner D, et al. Effects of bisoprolol fumarate on left ventricular size, function and exercise capacity in patients with heart failure: Analysis with magnetic resonance myocardial tagging. Am Heart J 2002;143:676-83.
    • (2002) Am Heart J , vol.143 , pp. 676-683
    • Dubach, P.1    Myers, J.2    Bonetti, P.3    Schertler, T.4    Froelicher, V.5    Wagner, D.6
  • 16
    • 0029034220 scopus 로고
    • Closed-line integral optimization edge detection algorithm and its application in equilibrium radionuclide angiography
    • Ekman M, Lomsky M, Strömblad GO, Carlsson S. Closed-line integral optimization edge detection algorithm and its application in equilibrium radionuclide angiography. J Nucl Med 1995;36:1014-8.
    • (1995) J Nucl Med , vol.36 , pp. 1014-1018
    • Ekman, M.1    Lomsky, M.2    Strömblad, G.O.3    Carlsson, S.4
  • 17
    • 0025215017 scopus 로고
    • Left ventricular volume calculation using a count-based ratio method applied to multigated radionuclide angiography
    • Massardo T, Gal RA, Grenier RP, Schmidt DH, Port SC. Left ventricular volume calculation using a count-based ratio method applied to multigated radionuclide angiography. J Nucl Med 1990;31:450-6.
    • (1990) J Nucl Med , vol.31 , pp. 450-456
    • Massardo, T.1    Gal, R.A.2    Grenier, R.P.3    Schmidt, D.H.4    Port, S.C.5
  • 19
    • 0021849148 scopus 로고
    • Spontaneous hemodynamic improvement or stabilization and associated biopsy findings in patients with congestive cardiomyopathy
    • Figulla HR, Rahlf G, Nieger M, Luig H, Kreuzer H. Spontaneous hemodynamic improvement or stabilization and associated biopsy findings in patients with congestive cardiomyopathy. Circulation 1985;71:1095-104.
    • (1985) Circulation , vol.71 , pp. 1095-1104
    • Figulla, H.R.1    Rahlf, G.2    Nieger, M.3    Luig, H.4    Kreuzer, H.5
  • 20
    • 0036895484 scopus 로고    scopus 로고
    • Effects of carvedilol on left ventricular remodelling and systolic function in elderly patients with heart failure
    • Palazzouli A, Bruni F, Pouccetti L, Pastorelli M, Angori P, Pasqui AL, et al. Effects of carvedilol on left ventricular remodelling and systolic function in elderly patients with heart failure. Eur J Heart Fail 2002;4:765-70.
    • (2002) Eur J Heart Fail , vol.4 , pp. 765-770
    • Palazzouli, A.1    Bruni, F.2    Pouccetti, L.3    Pastorelli, M.4    Angori, P.5    Pasqui, A.L.6
  • 21
    • 0343680211 scopus 로고    scopus 로고
    • Use of metoprolol CR/XL to maintain sinus rhythm after conversion from persistent atrial fibrillation: A randomized, double-blind, placebo-controlled study
    • Kuhlkamp V, Schirdewan A, Stangl K, Homberg M, Ploch M, Beck OA. Use of metoprolol CR/XL to maintain sinus rhythm after conversion from persistent atrial fibrillation: a randomized, double-blind, placebo-controlled study. J Am Coll Cardiol 2000;36:139-46.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 139-146
    • Kuhlkamp, V.1    Schirdewan, A.2    Stangl, K.3    Homberg, M.4    Ploch, M.5    Beck, O.A.6
  • 22
    • 0028922339 scopus 로고
    • Angiotensin-converting enzyme inhibitors and beta-blockers in long-term treatment of dilated cardiomyopathy
    • Regitz-Zagrosek V, Leuchs B, Krulls-Munch J, Fleck E. Angiotensin-converting enzyme inhibitors and beta-blockers in long-term treatment of dilated cardiomyopathy. Am Heart J 1985;129:754-61.
    • (1985) Am Heart J , vol.129 , pp. 754-761
    • Regitz-Zagrosek, V.1    Leuchs, B.2    Krulls-Munch, J.3    Fleck, E.4
  • 23
    • 0031033495 scopus 로고    scopus 로고
    • Additive beneficial effects of beta-blockers to angiotensin-converting enzyme inhibitors in the survival and ventricular enlargement (SAVE) study
    • Save investigators
    • Vantrimpont P, Rouleau JL, Wun CC, Ciampi A, Klein M, Sussex B, et al. Additive beneficial effects of beta-blockers to angiotensin-converting enzyme inhibitors in the survival and ventricular enlargement (SAVE) study. Save investigators. J Am Coll Cardiol 1997;29:229-36.
    • (1997) J Am Coll Cardiol , vol.29 , pp. 229-236
    • Vantrimpont, P.1    Rouleau, J.L.2    Wun, C.C.3    Ciampi, A.4    Klein, M.5    Sussex, B.6
  • 24
    • 0034816963 scopus 로고    scopus 로고
    • Regression of left ventricular remodelling in chronic heart failure: Comparative and combined effects of captopril and carvedilol
    • Khattar SR, Senior R, Soman P, van der Does R, Lahiri A. Regression of left ventricular remodelling in chronic heart failure:comparative and combined effects of captopril and carvedilol. Am Heart J 2001;142:704-13.
    • (2001) Am Heart J , vol.142 , pp. 704-713
    • Khattar, S.R.1    Senior, R.2    Soman, P.3    Van Der Does, R.4    Lahiri, A.5
  • 25
    • 0034911718 scopus 로고    scopus 로고
    • The Carvedilol and ACE-inhibitor remodelling mild heart failure evaluation trial (CARMEN)-rationale and design
    • Carmen Steering Committee and Investigators
    • Remme WJ. Carmen Steering Committee and Investigators. The Carvedilol and ACE-inhibitor remodelling mild heart failure evaluation trial (CARMEN)-rationale and design. Cardiovasc Drugs Ther 2001;15:9-10.
    • (2001) Cardiovasc Drugs Ther , vol.15 , pp. 9-10
    • Remme, W.J.1
  • 26
    • 0036802702 scopus 로고    scopus 로고
    • Clinical trials update from the European Society of Cardiology: CARMEN, EARTH, OPTIMAAL, ACE, TEN-HMS, MAGIC, SOLVD-X and PATH-CHF II
    • Coletta AP, Louis AA, Clark A, Nikitin N, Cleland JGF. Clinical trials update from the European Society of Cardiology: CARMEN, EARTH, OPTIMAAL, ACE, TEN-HMS, MAGIC, SOLVD-X and PATH-CHF II. Eur J Heart Fail 2002;4:661-6.
    • (2002) Eur J Heart Fail , vol.4 , pp. 661-666
    • Coletta, A.P.1    Louis, A.A.2    Clark, A.3    Nikitin, N.4    Cleland, J.G.F.5
  • 27
    • 85058203078 scopus 로고    scopus 로고
    • Long-term effects of bisoprolol compared with imidapril on left ventricular remodeling after reperfusion in acute myocardial infarction: An angiographic study in patients with maintained vessel patency
    • Yoshitomi Y, Kojima S, Michiko Y, Toshihiko S, Matsumotu Y, Kuramochi M. Long-term effects of bisoprolol com pared with imidapril on left ventricular remodeling after reperfusion in acute myocardial infarction: an angiographic study in patients with maintained vessel patency. Am Heart J 2000;140:e27.
    • (2000) Am Heart J , vol.140
    • Yoshitomi, Y.1    Kojima, S.2    Michiko, Y.3    Toshihiko, S.4    Matsumotu, Y.5    Kuramochi, M.6
  • 28
    • 0035489952 scopus 로고    scopus 로고
    • Effect of early treatment with capotopril and metoprolol singly and together on postinfarction left ventricular remodeling
    • On behalf of RIMA Researchers
    • Ricci R, Colletta C, Ceci V, Pajes G, Lucia R, Salustri A, et al. On behalf of RIMA Researchers. Effect of early treatment with capotopril and metoprolol singly and together on postinfarction left ventricular remodeling. Am Heart J 2001;142(4):E5.
    • (2001) Am Heart J , vol.142 , Issue.4
    • Ricci, R.1    Colletta, C.2    Ceci, V.3    Pajes, G.4    Lucia, R.5    Salustri, A.6
  • 29
    • 0029084860 scopus 로고
    • Myocardial blood flow response to pacing tachycardia and to dipyridamole infusion in patients with dilated cardiomyopathy without overt heart failure. A quantitative assessment by positron emission tomography
    • Neglia D, Parodi O, Galoppin M, Sambuceti G, Giorgetti A, Pratali L, et al. Myocardial blood flow response to pacing tachycardia and to dipyridamole infusion in patients with dilated cardiomyopathy without overt heart failure. A quantitative assessment by positron emission tomography. Circulation 1995;92:796-804.
    • (1995) Circulation , vol.92 , pp. 796-804
    • Neglia, D.1    Parodi, O.2    Galoppin, M.3    Sambuceti, G.4    Giorgetti, A.5    Pratali, L.6
  • 30
    • 0019520743 scopus 로고
    • Changes in ischemic blood flow distribution and dynamic severity of coronary stenosis induced by beta blockade in canine heart
    • Buck JD, Hardman HF, Warltier DC, Garett JG. Changes in ischemic blood flow distribution and dynamic severity of coronary stenosis induced by beta blockade in canine heart. Circulation 1981;64:708-15.
    • (1981) Circulation , vol.64 , pp. 708-715
    • Buck, J.D.1    Hardman, H.F.2    Warltier, D.C.3    Garett, J.G.4
  • 31
    • 0023627082 scopus 로고
    • Cardiac anti-ischemic effects of metoprolol: Role of beta-blockade within the ischemic region
    • Åblad B, Abrahamsson T, Adler G, Björkman J-A, Bjurö T, Ek L, et al. Cardiac anti-ischemic effects of metoprolol: role of beta-blockade within the ischemic region. J Cardiovasc Pharm 1987;10(suppl):S117-S125.
    • (1987) J Cardiovasc Pharm , vol.10 , Issue.SUPPL.
    • Åblad, B.1    Abrahamsson, T.2    Adler, G.3    Björkman, J.-A.4    Bjurö, T.5    Ek, L.6
  • 32
    • 0021325024 scopus 로고
    • Effects of three bradycardic drugs on regional myocardial flow and function in areas to a total or partial coronary occlusion in dogs
    • Gross DJ, Lamping KG, Warltier DC, Hardman HF. Effects of three bradycardic drugs on regional myocardial flow and function in areas to a total or partial coronary occlusion in dogs. Circulation 1984;69:391-9.
    • (1984) Circulation , vol.69 , pp. 391-399
    • Gross, D.J.1    Lamping, K.G.2    Warltier, D.C.3    Hardman, H.F.4
  • 33
    • 0032966576 scopus 로고    scopus 로고
    • Beta blockers reduce the release and synthesis of endothelin-1 in human endothelial cells
    • Garlichs CDE, Zhang H, Mugge A, Daniel WG. Beta blockers reduce the release and synthesis of endothelin-1 in human endothelial cells. Eur J Clin Invest 1999;29:12.
    • (1999) Eur J Clin Invest , vol.29 , pp. 12
    • Garlichs, C.D.E.1    Zhang, H.2    Mugge, A.3    Daniel, W.G.4
  • 35
    • 0025071544 scopus 로고
    • Effect of beta-adrenergic blockade on myocardial function and energetics in congestive heart failure
    • Eichhorn EJ, Bedotto JB, Malloy CR, Hatfiled BA, Deichman D, Brown M, et al. Effect of beta-adrenergic blockade on myocardial function and energetics in congestive heart failure. Circulation 1990;82:473-83.
    • (1990) Circulation , vol.82 , pp. 473-483
    • Eichhorn, E.J.1    Bedotto, J.B.2    Malloy, C.R.3    Hatfiled, B.A.4    Deichman, D.5    Brown, M.6
  • 36
    • 0026048681 scopus 로고
    • Exercise hemodynamics and myocardial metabolism during long-term betablockade in severe heart failure
    • Andersson B, Blomström-Lundquist C, Hedner T, Waagstein F. Exercise hemodynamics and myocardial metabolism during long-term betablockade in severe heart failure. J Am Coll Cardiol 1991;18:1059-66.
    • (1991) J Am Coll Cardiol , vol.18 , pp. 1059-1066
    • Andersson, B.1    Blomström-Lundquist, C.2    Hedner, T.3    Waagstein, F.4
  • 37
    • 0034816433 scopus 로고    scopus 로고
    • Selective beta-1-blockade improves cardiac bioenergetics and function and decreases neuroendocrine activation in rats during early postinfarct remodeling
    • Omerovic E, Bollano E, Mobini R, Basetti M, Kujacic V, Soussi B, et al. Selective beta-1-blockade improves cardiac bioenergetics and function and decreases neuroendocrine activation in rats during early postinfarct remodeling. Biochem Biophys Res Commun 2001;281:491-8.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 491-498
    • Omerovic, E.1    Bollano, E.2    Mobini, R.3    Basetti, M.4    Kujacic, V.5    Soussi, B.6
  • 39
    • 0028340303 scopus 로고
    • Improved exercise hemodynamic status in dilated cardiomyopathy after beta-adrenergic blockade treatment
    • Andersson B, Hamm C, Persson S, Wikstrom G, Sinagra G, Hjalmarsson A, et al. Improved exercise hemodynamic status in dilated cardiomyopathy after beta-adrenergic blockade treatment. J Am Coll Cardiol 1994;23:1397-404.
    • (1994) J Am Coll Cardiol , vol.23 , pp. 1397-1404
    • Andersson, B.1    Hamm, C.2    Persson, S.3    Wikstrom, G.4    Sinagra, G.5    Hjalmarsson, A.6
  • 40
    • 0346552176 scopus 로고    scopus 로고
    • Effect of carvedilol on myocardial ischaemia, hibernation and viability in patients with left ventricular dysfunction due to CAD
    • Cleland JGF, Penell D, Ray S, Coats A, Lahiri A, Dalle Mule J, et al. Effect of carvedilol on myocardial ischaemia, hibernation and viability in patients with left ventricular dysfunction due to CAD. Eur Heart J 2002;23(Suppl. 81):517.
    • (2002) Eur Heart J , vol.23 , Issue.SUPPL. 81 , pp. 517
    • Cleland, J.G.F.1    Penell, D.2    Ray, S.3    Coats, A.4    Lahiri, A.5    Dalle Mule, J.6
  • 42
    • 0034814619 scopus 로고    scopus 로고
    • Metoprolol controlled release/extended release in patients with severe heart failure: Analysis of the experience in the MERIT HF study
    • Goldstein S, Fagerberg B, Hjalmarson A, Kjekshus J, Waagstein F, Wedel H, et al. Metoprolol controlled release/extended release in patients with severe heart failure:analysis of the experience in the MERIT HF study. J Am Coll Cardiol 2001;38:932-8.
    • (2001) J Am Coll Cardiol , vol.38 , pp. 932-938
    • Goldstein, S.1    Fagerberg, B.2    Hjalmarson, A.3    Kjekshus, J.4    Waagstein, F.5    Wedel, H.6
  • 43
    • 0026704692 scopus 로고
    • Effects of ACE inhibitor enalapril on long-term progression of left ventricular dysfunction in patients with heart failure
    • SOLVD Investigators
    • Konstam MA, Rousseau MF, Kronenberg MW, Udelson JE, Melin J, Stewart D, et al. Effects of ACE inhibitor enalapril on long-term progression of left ventricular dysfunction in patients with heart failure. SOLVD Investigators. Circulation 1992;86:431-8.
    • (1992) Circulation , vol.86 , pp. 431-438
    • Konstam, M.A.1    Rousseau, M.F.2    Kronenberg, M.W.3    Udelson, J.E.4    Melin, J.5    Stewart, D.6


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