The cytotoxicity of Scytosiphon lomentaria against HL-60 promyelocytic leukemia cells

Cancer Biotherapy and Radiopharmaceuticals

Volumn 19, Issue 5, 2004, Pages 641-648

  Kim, Sang Cheol ^a   Park, Soo Young ^a   Hyoun, Jae Hee ^a   Cho, Heeyeong ^b   Kang, Ji Hoon ^a   Lee, Young Ki ^a   Park, Doek Bae ^a   Yoo, Eun Sook ^a   Kang, Hee Kyoung ^a  

^a Jeju National University School of Medicine   (South Korea)

^b Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Apoptosis; Bax; Bcl 2; c Myc; Caspase 3; HL 60; Scytosiphon lomentaria

Indexed keywords

ACETIC ACID ETHYL ESTER; CASPASE 3; CYTOTOXIC AGENT; DNA FRAGMENT; NATURAL PRODUCT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; SCYTOSIPHON LOMENTARIA EXTRACT; UNCLASSIFIED DRUG;

ALGA; APOPTOSIS; ARTICLE; CANCER INHIBITION; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOTOXICITY; DIPLOIDY; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; LEUKEMIA CELL; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; SCYTOSIPHON LOMENTARIA;

ACETATES; ALGAE; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL NUCLEUS; CHROMATIN; DNA; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; G1 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; HL-60 CELLS; HUMANS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MYC; TIME FACTORS;

EID: 9144235942     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/1084978042484768     Document Type: Article

References (31)

1. Mayer AM, Virginia VK. Marine pharmacology in 1999: Antitumor and cytotoxic compounds. Anticancer Res 2001;21:2489.
2. Meyer BN, Ferrigni NR, Putnam JE, et al. Brine shrimp: A convenient general bioassay for active plant constituents. Planta Medica 1982;45:31.
3. Mayer AM, Gustafson KR. Marine pharmacology in 2000: Antitumor and cytotoxic compounds. Int J Cancer 2003;105:291.
4. Pettit GR, Herald CL, Doubek DL, et al. Isolation and structure of bryostatin 1. J Am Chem Soc 1982;104:6846.
5. Dale IL, Gescher A. Effects of activators of protein kinase C, including bryostatins 1 and 2, on the growth of A549 human lung carcinoma cells. Int J Cancer 1989;43:158.
6. Asiedu C, Biggs J, Lilly M, et al. Inhibition of leukemic cell growth by the protein kinase C activator bryostatin 1 correlates with the dephosphorylation of cyclin-dependent kinase 2. Cancer Res 1995;55:101.
7. Kim SC, Park SY, Kim BS, et al. Cell growth inhibitory effects of extracts of marine algae growing in Jeju. Cheju J Life Sci 2002;5:15.
8. Lee IK, Kang JW. A checklist of marine algae in Korea. Korean Soc Phycol 1986;1:311.
9. Carmichael J, DeGraff WG, Gazdar AF, et al. Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemisensitivity testing. Cancer Res 1987;47:936.
10. Oberhammer F, Wilson JW, Dive C, et al. Apoptosis death in epithelial cell: Cleavage of DNA to 300 and/or 50 kb fragments prior to in the absence of internucleasomal fragmentation. EMBO J 1993;12:3679.
11. Sherwood SW, Sheridan JP, Schimke RT. Induction of apoptosis by the antitubulin drug colcemid: Relationship of mitotic checkpoint control to the induction of apoptosis in HeLa S3 cells. Exp Cell Res 1994;215:373.
12. Wyllie AH. Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: An overview. Cancer Metast Rev 1992;11:95.
13. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248.
14. Henriksson M, Luscher B. Proteins of the myc network: Essential regulators of cell growth and differentiation. Adv Cancer Res 1996;68:109.
15. Iguchi-Ariga SM, Itani T, Kiji Y, et al. Possible function of the c-myc product: Promotion of cellular DNA replication. EMBO J 1987;6:2365.
16. Kato GJ, Dang CV. Function of the c-myc oncoprotein. FASEB J 1992;6:3065.
17. Kimura S, Maekawa T, Hirakawa K, et al. Alterations of c-myc expression by antisense oligodeoxynucleotides enhance the induction of apoptosis in HL-60 cells. Cancer Res 1995;55:1379.
18. Hong SH, Jeong SY, Ahn SG, et al. Active adenosine transporter-mediated adenosine entrance into HL-60 cells leads to the induction of apoptosis through down-regulation of c-myc. Exp Mol Med 1997;29:183.
19. Thompson EB. The many roles of c-myc in apoptosis. Ann Rev Physiol 1998;60:575.
20. Prendergast GC. Mechanisms of apoptosis by c-myc. Oncogene 1999;18:2967.
21. Kamesaki H. Mechanism involved in chemotherapy-induced apoptosis and their implications in cancer chemotherapy. Int J Hematol 1998;68:29.
22. Kaufman SH, Earnshaw WC. Induction of apoptosis by cancer chemotherapy. Exp Cell Res 2000;256:42.
23. Bold RJ, Termuhlen PM, McConkey DJ. Apoptosis, cancer, and cancer therapy. J Surg Oncol 1997;6:133.
24. Buttke MT, Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today 1994;15:7.
25. Wyllie AH. The biology of cell death in tumors. Anticancer Res 1985;5:131.
26. Loo DT, Rillema JR. Measurement of cell death. Meth Cell Biol 1998;57:251.
27. 2+ pool depletion. Oncogene 1996;12:2051.
28. Baffy G, Miyashita T, Williamson JR, et al. Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production. J Biol Chem 1993;268:6511.
29. Wei MC, Zong WX, Cheng EH-Y, et al. Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death. Science 2001;292:727.
30. Zou H, Henzel WJ, Liu X, et al. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 1997;90:405.
31. Fernandes-Alnemri T, Litwack G, Alnemri ES. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J Biol Chem 1994;269:30761.