Deep venous thrombosis, myocardial infarction, and occlusion of vascular access associated with heparin-induced thrombocytopenia in a diabetic hemodialysis patient

Clinical and Experimental Nephrology

Volumn 7, Issue 4, 2003, Pages 306-310

  Igaki, Naoya ^a   Matsuda, Tomokazu ^a   Yatani, Hirofumi ^a   Kawaguchi, Takayuki ^a   Kida, Aritoshi ^a   Yanase, Kimihiko ^a   Moriguchi, Rintarou ^a   Sakai, Makoto ^a   Tamada, Fumihiko ^a   Goto, Takeo ^a  

^a Takasago Municipal Hospital   (Japan)

Author keywords

Anti platelet factor 4 heparin antibody; Argatroban; Heparin induced thrombocytopenia; Low molecular weight heparins; Warfarin

Indexed keywords

HEPARIN; THROMBOCYTE FACTOR;

ADULT; ARTICLE; BLOOD VESSEL OCCLUSION; CASE REPORT; DEEP VEIN THROMBOSIS; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DIFFERENTIAL DIAGNOSIS; FEMALE; HEART INFARCTION; HEMODIALYSIS; HUMAN; KIDNEY FAILURE; THROMBOCYTE COUNT; THROMBOCYTOPENIA; THROMBOEMBOLISM; TREATMENT PLANNING; VASCULAR ACCESS;

ANTICOAGULANTS; CATHETERS, INDWELLING; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; FEMALE; FIBRINOLYTIC AGENTS; HEPARIN; HUMANS; KIDNEY FAILURE, CHRONIC; MIDDLE AGED; MYOCARDIAL INFARCTION; PHLEBOGRAPHY; RENAL DIALYSIS; THROMBOCYTOPENIA; TICLOPIDINE; VENOUS THROMBOSIS; WARFARIN;

EID: 9144232261     PISSN: 13421751     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10157-003-0251-1     Document Type: Article

References (28)

1. Chong B. Heparin-induced thrombocytopenia. Br J Haematol 1995;89:431-9.
2. Warkentin TE, Sheppard JA, Horsewood P, Simpson PJ, Moore JC, Kelton JG. Impact of the patient population on the risk for heparin-induced thrombocytopenia. Blood 2000;96:1703-8.
3. Deitcher SR, Carman TL. Heparin-induced thrombocytopenia: natural history, diagnosis, and management. Vasc Med 2001;6:113-9.
4. Girolami B, Prandoni P, Stefani PM, Tanuo C, Sabbion P, Eichler P, et al. The incidence of heparin-induced thrombocytopenia in hospitalized medical patients treated with subcutaneous unfractionated heparin. A prospective cohort study. Blood 2002;101:2955-9.
5. Mureebe L, Silver D, Missouri C. Heparin-induced thrombocytopenia: pathophysiology and management. Vasc Endovasc Surg 2002;36:163-70.
6. Fabris F, Luzzatto G, Soini B, Ramon R, Scandellari R, Randi ML, et al. Risk factor for thrombosis in patients with immune mediated heparin-induced thrombocytopenia. J Intern Med 2002;252:149-54.
7. Rice L, Nguyen PH, Vann AR. Preventing complications in heparin-induced thrombocytopenia. Postgrad Med J 2002;112:85-9.
8. Lubenow N, Kempf R, Eichner A, Eichler P, Carlsson LE, Greinacher A. Heparin-induced thrombocytopenia. Temporal pattern of thrombocytopenia in relation to initial use or reexposure to heparin. Chest 2002;122:37-42.
9. Ziporen L, Li ZQ, Park KS, Sabnekar P, Liu WY, Arepally G, et al. Defining an antigenic epitope on platelet factor 4 associated with heparin-induced thrombocytopenia. Blood 1998;92:3250-9.
10. Newman PM, Chong BH. Heparin-induced thrombocytopenia: new evidence for the dynamic binding of purified anti-PF4-heparin antibodies to platelets and the resultant platelet activation. Blood 2000;96:182-7.
11. Yamamoto S, Koide M, Matsuo M, Suzuki S, Ohtaka M, Saika S, et al. Heparin-induced thrombocytopenia in hemodialysis patients. Am J Kidney Dis 1996;28:82-5.
12. Sitter T, Spannagl M, Banas B, Schiffl H. Prevalence of heparin-induced PF4-heparin antibodies in hemodialysis patients. Nephron 1998;79:245-6.
13. Finazzi G, Remuzzi G. Heparin-induced thrombocytopenia - background and implications for haemodialysis. Nephrol Dial Transplant 1996;11:2120-2.
14. O'Shea SI, Sands JJ, Nudo SA, Ortel TL. Frequency of antiheparin-platelet factor 4 antibodies in hemodialysis patients and correlation with recurrent vascular access thrombosis. Am J Hematol 2002;69:72-3.
15. Warkentin TE, Levine MN, Hirsh J, Horsewood P, Roberts RS, Tech M, et al. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995;332:1330-5.
16. Lewis BE, Walenga JM, Wallis DE. Anticoagulation with Novastan (argatroban) in patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome. Semin Thromb Hemost 1997;23:197-202.
17. Alving BM. How I treat heparin-induced thrombocytopenia and thrombosis. Blood 2003;101:31-7.
18. Mammen E. Low molecular weight heparins and heparin-induced thrombocytopenia. Clin Appl Thromb Hemost 1999;5(Suppl 1):S72-5.
19. Pouplard C, May MA, Iochmann S, Amiral J, Vissac AM, Marchand M, et al. Antibodies to platelet factor 4-heparin after cardiopulmonary bypass in patients anticoagulated with unfractionated heparin or a low-molecular-weight heparin. Clinical implications for heparin-induced thrombocytopenia. Circulation 1999;99:2530-6.
20. Cohen M. Heparin-induced thrombocytopenia and the clinical use of low molecular weight heparins in acute coronary syndromes. Semin Hematol 1999;36 (Suppl 1):33-6.
21. Last EL, Nakov R, Misselwitz F, Breddin HK, Bauersachs R. Incidence and clinical relevance of heparin-induced antibodies in patients with deep vein thrombosis treated with unfractionated or low-molecular-weight heparin. Br J Haematol 2002;118:1137-42.
22. Warkentin TE, Elavathil LJ, Hayward CP, Johnston MA, Russett JI, Kelton JG. The pathogenesis of venous limb gangrene associated with heparin-induced thrombocytopenia. Ann Intern Med 1997;127:804-12.
23. Smythe MA, Warkentin TE, Stephens JL, Zakalik D, Mattson JC. Venous limb gangrene during overlapping therapy with warfarin and a direct thrombin inhibitor for immune heparin-induced thrombocytopenia. Am J Hematol 2002;71:50-2.
24. Warkentin TE. Venous limb gangrene during warfarin treatment of cancer-associated deep venous thrombosis. Ann Intern Med 2001;135:589-93.
25. Wallis DE, Quintos R, Wehrmacher W, Messmore H. Safety of warfarin anticoagulation in patients with heparin-induced thrombocytopenia. Chest 1999;116:1333-8.
26. Matsuo T, Yamada T, Chikahira C, Kadowaki S. Effect of aspirin on heparin-induced thrombocytopenia (HIT) in a patient requiring hemodialysis. Blut 1989;59:393-5.
27. Koide M, Yamamoto S, Matsuo M, Suzuki S, Arima N, Matsuo M. Anticoagulation for heparin-induced thrombocytopenia with spontaneous platelet aggregation in a patient requiring haemodialysis. Nephrol Dial Transplant 1995;10:2137-40.
28. Lewis BE, Wallis DE, Berkowitz SD, Matthai WH, Fareed J, Walenga JM, et al. for the ARG-911 study investigators. Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia. Circulation 2001;103:1838-43.