Inhibition of G Protein-Coupled and ATP-Sensitive Potassium Currents by 2-Methyl-3-(3,5-diiodo-4-carboxymethoxybenzyl)benzofuran (KB130015), an Amiodarone Derivative

Journal of Pharmacology and Experimental Therapeutics

Volumn 308, Issue 1, 2004, Pages 134-142

  Brandts, Bodo ^a   Borchard, R ^a   Macianskiene, R ^b,c   Gendviliene, V ^c   Dirkmann, D ^a   Van Bracht, M ^a   Prull, M ^a   Meine, M ^a   Wickenbrock, I ^a   Mubagwa, K ^b   Trappe, H J ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 3 (3,5 DIIODO 4 CARBOXYMETHOXYBENZYL)BENZOFURAN; 2,4 DINITROPHENOL; ACETYLCHOLINE; ADENOSINE RECEPTOR; ADENOSINE TRIPHOSPHATE; AMIODARONE; AMIODARONE DERIVATIVE; CARBACHOL; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INWARDLY RECTIFYING POTASSIUM CHANNEL; KB 130015; LIOTHYRONINE; MUSCARINIC RECEPTOR; UNCLASSIFIED DRUG;

ACTION POTENTIAL DURATION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATP SENSITIVE POTASSIUM CURRENT; BACKGROUND INWARDLY RECTIFYING POTASSIUM CHANNEL; CONCENTRATION RESPONSE; CONDUCTANCE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SENSITIVITY; G PROTEIN COUPLED POTASSIUM CURRENT; GUINEA PIG; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; IC 50; METABOLIC INHIBITION; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; VOLTAGE CLAMP;

ACTION POTENTIALS; ADENOSINE TRIPHOSPHATE; AMIODARONE; ANIMALS; BENZOFURANS; CELLS, CULTURED; DRUG INTERACTIONS; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUINEA PIGS; HEART ATRIA; MUSCLE CELLS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING;

EID: 9144225356     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.057646     Document Type: Article

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