Quantitative fish determination of chromosome 3 arm imbalances in lung tumors by automated image cytometry

Medical Science Monitor

Volumn 10, Issue 11, 2004, Pages

  Truong, Khuong ^a,b   Gibaud, Anne ^a   Zalcman, Gérard ^c   Guilly, Marie Noëlle ^d   Antoine, Martine ^e   Commo, Frédéric ^e   Fouquet, Coralie ^e   Cadranel, Jacques ^e   Soussi, Thierry ^e   Dutrillaux, Bernard ^a,d   Malfoy, Bernard ^a,f  

^a INSTITUT CURIE   (France)

^b IMSTAR   (France)

^c CHU CÔTE DE NACRE   (France)

^d INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^e HÔPITAL TENON   (France)

^f CNRS   (France)

Author keywords

Cancer; Chromosome; Image cytometry; Imbalance; Lung

Indexed keywords

GENE PRODUCT; PROTEIN P53;

ARTICLE; AUTOMATION; CANCER DIAGNOSIS; CELL POPULATION; CHROMOSOME 3; CHROMOSOME REARRANGEMENT; COHORT ANALYSIS; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; DNA PROBE; FEMALE; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMAGE CYTOMETRY; IMMUNOHISTOCHEMISTRY; LUNG BIOPSY; LUNG CANCER; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; PRECANCER; QUANTITATIVE DIAGNOSIS; TUMOR SUPPRESSOR GENE;

CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMAL INSTABILITY; CHROMOSOMES, HUMAN, PAIR 3; COHORT STUDIES; FEMALE; HUMANS; IMAGE CYTOMETRY; IN SITU HYBRIDIZATION, FLUORESCENCE; LUNG NEOPLASMS; MALE; MUTATION;

EID: 9144224370     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Carbone DP: The biology of lung cancer. Semin Oncol, 1997; 24(4): 388-401
2. Wistuba II, Behrens C, Milchgrub S et al: Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma. Oncogene, 1999; 18(3): 643-50
3. Braithwaite KL, Rabbitts PH: Multi-step evolution of lung cancer. Semin Cancer Biol, 1999; 9(4): 255-65
4. Powell CA, Klares S, O'Connor G, Brody JS: Loss of heterozygosity in epithelial cells obtained by bronchial brushing: clinical utility in lung cancer. Clin Cancer Res, 1999; 5(8): 2025-34
5. Sanz-Ortega J, Saez MC, Sierra E et al: 3p21, 5q21, and 9p21 allelic deletions are frequently found in normal bronchial cells adjacent to non-small-cell lung cancer, while they are unusual in patients with no evidence of malignancy. J Pathol, 2001; 195(4): 429-34
6. Zabarovsky ER, Lerman MI, Minna JD: Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers. Oncogene, 2002; 21 (45): 6915-35
7. Sekido Y, Fong KM, Minna JD: Molecular genetics of lung cancer. Annu Rev Med, 2003; 54: 73-87
8. Testa JR, Liu Z, Feder M et al: Advances in the analysis of chromosome alterations in human lung carcinomas. Cancer Genet Cytogenet, 1997; 95(1): 20-32
9. Flury-Herard A, Viegas-Pequignot E, De Cremoux H et al: Cytogenetic study of five cases of lung adenosquamous carcinomas. Cancer Genet Cytogenet, 1992; 59(1): 1-8
10. Pei J, Balsara BR, Li W et al: Genomic imbalances in human lung adenocarcinomas and squamous cell carcinomas. Genes Chromosomes Cancer, 2001; 31(3): 282-87
11. Truong K, Guilly MN, Gerbault-Seureau M et al: Quantitative FISH by image cytometry for the detection of chromosome 1 imbalances in breast cancer: a novel approach analyzing chromosome rearrangements within interphase nuclei. Lab Invest, 1998; 78(12): 1607-13
12. Truong K, Guilly MN, Gerbault-Seureau M et al: Evidence for in vitro selection during cell culturing of breast cancer: detection by flow and image cytometry. Cancer Genet Cytogenet, 1999; 114(2): 154-55
13. Truong K, Vielh P, Guilly MN et al: Quantitative FISH analysis on interphase nuclei may improve diagnosis of DMA diploid breast cancers. Diagn Cytopathol, 2002; 26(4): 213-16
14. Truong K, Gerbault-Seureau M, Guilly MN et al: Quantitative fluorescence in situ hybridization in lung cancer as a diagnostic marker. J Mol Diagn, 1999; 1(1): 33-37
15. Holmila R, Fouquet C, Cadranel J et al: Splice mutations in the p53 gene: case report and review of the literature. Hum Mutat, 2003; 21 (1): 101-2
16. van den Engh G, Trask B, Cram S, Bartholdi M: Preparation of chromosome suspensions for flow cytometry. Cytometry, 1984; 5(2): 108-17
17. De Solorzano CO, Malladi R, Lelievre SA, Lockett SJ: Segmentation of nuclei and cells using membrane related protein markers. J Microsc, 2001; 201 (Pt 3): 404-15
18. Truong K, Boenders J, Maciorowski Z et al: Signal amplification of FISH for automated detection using image cytometry. Anal Cell Pathol, 1997; 13(3): 137-46
19. van de Rijke FM, Vrolijk H, Sloos W et al: Sample preparation and in situ hybridization techniques for automated molecular cytogenetic analysis of white blood cells. Cytometry, 1996; 24(2): 151-57
20. Ross JS, Fletcher JA, Linette GP et al: The Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapy. Oncologist, 2003; 8(4): 307-25
21. Di Leo A, Dowsett M, Horten B, Penault-Llorca F: Current status of HER2 testing. Oncology, 2002; 63(Suppl. 1): 25-32
22. Dutrillaux B, Gerbault-Seureau M, Remvikos Y et al: Breast cancer genetic evolution: I. Data from cytogenetics and DNA content. Breast Cancer Res Treat, 1991; 19(3): 245-55
23. Popescu NC, Zimonjic DB: Chromosome and gene alterations in breast cancer as markers for diagnosis and prognosis as well as pathogenetic targets for therapy. Am J Med Genet, 2002; 115(3): 142-49
24. Goeze A, Schluns K, Wolf G et al: Chromosomal imbalances of primary and metastatic lung adenocarcinomas. J Pathol, 2002; 196(1): 8-16
25. Truong K, Vielh P, Malfoy B et al: Fluorescence-based analysis of DNA ploidy and cell proliferation within fine-needle samplings of breast tumors: a new approach using automated image cytometry. Cancer, 1998; 84(5): 309-16
26. Chung GT, Sundaresan V, Hasleton P et al: Sequential molecular genetic changes in lung cancer development. Oncogene, 1995; 11(12): 2591-98