Tryptamine-based human β 3-adrenergic receptor agonists. Part 1: SAR studies of the 7-position of the indole ring

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 24, 2004, Pages 5959-5962

  Mizuno, Kazuhiro ^a   Sawa, Masaaki ^a   Harada, Hiroshi ^a   Tateishi, Hirotaka ^a   Oue, Mayumi ^a   Tsujiuchi, Hiroshi ^a   Furutani, Yasuji ^a   Kato, Shiro ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

3 Adrenergic receptor; Agonist; Tryptamine

Indexed keywords

BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR; INDOLE; SULFONAMIDE; TRYPTAMINE; TRYPTAMINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ADRENERGIC BETA-AGONISTS; DRUG EVALUATION, PRECLINICAL; HUMANS; INDOLES; MOLECULAR CONFORMATION; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, ADRENERGIC, BETA-3; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; THIOPHENES; TRYPTAMINES;

EID: 8844274195     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.10.035     Document Type: Article

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