Comparative study of proton and phosphorus magnetic resonance spectroscopy in schizophrenia at 4 Tesla

Psychiatry Research - Neuroimaging

Volumn 132, Issue 1, 2004, Pages 33-39

  Théberge, Jean ^a   Al Semaan, Yousef ^a,b   Jensen, J Eric ^a,c   Williamson, Peter C ^a,e   Neufeld, Richard W J ^a   Menon, Ravi S ^a,d   Schaefer, Betsy ^a   Densmore, Maria ^a   Drost, Dick J ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^c HARVARD MEDICAL SCHOOL   (United States)

^d ROBARTS RESEARCH INSTITUTE   (Canada)

^e LONDON HEALTH SCIENCES CENTRE   (Canada)

Author keywords

High field; Neurodegeneration; Phospholipid metabolism; Phosphorus; Proton; Schizophrenia; Spectroscopy

Indexed keywords

GLUTAMINE; GLYCEROPHOSPHORYLCHOLINE; N ACETYLASPARTIC ACID; PHOSPHOETHANOLAMINE; PHOSPHOLIPID; PHOSPHORUS 31; PROTON;

ADULT; ARTICLE; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; IN VIVO STUDY; INTERMETHOD COMPARISON; LEFT HEMISPHERE; MALE; MEMBRANE; MENTAL PATIENT; METABOLITE; NEUROTRANSMISSION; PHOSPHOLIPID METABOLISM; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCHIZOPHRENIA; SPECTRUM; THALAMUS;

ADULT; BRAIN; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; NERVE DEGENERATION; PHOSPHOLIPIDS; PHOSPHORUS; PROTONS; SCHIZOPHRENIA;

EID: 8844265381     PISSN: 09254927     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2004.08.001     Document Type: Article

References (38)

1. G.E. Alexander, M.D. Crutcher, and M.R. DeLong Basal ganglia- thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions Progress in Brain Research 85 1990 119 146
2. N. Andreasen Scale for the Assessment of Negative Symptoms (SANS) 1984 The University of Iowa Iowa City, IA
3. N. Andreasen Scale for the Assessment of Positive Symptoms (SAPS) 1984 The University of Iowa Iowa City, IA
4. D.L. Arnold, P.M. Matthews, G. Francis, and J. Antel Proton magnetic resonance spectroscopy of human brain in vivo in the evaluation of multiple sclerosis: assessment of the load of disease Magnetic Resonance in Medicine 14 1 1990 154 159
5. R. Bartha, P.C. Williamson, D.J. Drost, A. Malla, T.J. Carr, L. Cortese, G. Canaran, R.J. Rylett, and R.W. Neufeld Measurement of glutamate and glutamine in the medial prefrontal cortex of never-treated schizophrenic patients and healthy controls by proton magnetic resonance spectroscopy Archives of General Psychiatry 54 10 1997 959 965
6. 1H MR spectra: prior knowledge, peak elimination, and filtering NMR in Biomedicine 12 4 1999 205 216
7. 1H spectroscopy at 1.5 and 4.0 Tesla Magnetic Resonance in Medicine 44 2 2000 185 192
8. K.Z. Bezchlibnyk-Butler, and J.J. Jeffries Clinical Handbook of Psychotropic Drugs 2002 Hogrefe and Huber Publishers Seattle, WA
9. P.F. Buckley, and L. Friedman Magnetic resonance spectroscopy. Bridging the neurochemistry and neuroanatomy of schizophrenia British Journal of Psychiatry 176 2000 203 205
10. A. Carlsson, L.O. Hansson, N. Waters, and M.L. Carlsson A glutamatergic deficiency model of schizophrenia British Journal of Psychiatry Supplement 37 1999 2 6
11. M.B. First, R.L. Spitzer, M. Gibbon, and J.B.W. Williams Structured Clinical Interview (SCID) for DSM-IV Axis 1 Disorders 1997 American Psychiatric Press Washington, DC
12. W.F. Gattaz, M. Kollisch, T. Thuren, J.A. Virtanen, and P.K. Kinnunen Increased plasma phospholipase-A2 activity in schizophrenic patients: reduction after neuroleptic therapy Biological Psychiatry 22 4 1987 421 426
13. R. Gruetter Automatic, localized in vivo adjustment of all first- and second-order shim coils Magnetic Resonance in Medicine 29 6 1993 804 811
14. 1H MRS in the evaluation of Huntington's and Parkinson's diseases Neurology 50 4 1998 1033 1040
15. D.C. Javitt, and S.R. Zukin Recent advances in the phencyclidine model of schizophrenia American Journal of Psychiatry 148 10 1991 1301 1308
16. 31P-MRS: measuring the phospholipid resonances at 4 Tesla from small voxels NMR in Biomedicine 15 5 2002 338 347
17. 31P Chemical Shift Imaging Study at 4.0 Tesla. (Abstract #237) Proceedings of the International Society of Magnetic Resonance in Medicine Tenth Meeting, Honolulu, HI 2002
18. 31P-MRS study at 4.0 Tesla British Journal of Psychiatry 180 2002 39 44
19. Y. Ke, J.T. Coyle, N.S. Simpson, S.A. Gruber, P.F. Renshaw, and D.A. Yurgelun-Todd Brain NAA T2 Values are Significantly Lower in Schizophrenia. (Abstract #976) Proceedings of the International Society for Magnetic Resonance in Medicine Tenth Meeting, Honolulu, HI 2002
20. M.S. Keshavan, J.A. Stanley, and J.W. Pettegrew Magnetic resonance spectroscopy in schizophrenia: methodological issues and findings-part II Biological Psychiatry 48 5 2000 369 380
21. P.J. Magistretti, L. Pellerin, D.L. Rothman, and R.G. Shulman Energy on demand Science 283 5401 1999 496 497
22. T. Michaelis, K.D. Merboldt, H. Bruhn, W. Hanicke, and J. Frahm Absolute concentrations of metabolites in the adult human brain in vivo: quantification of localized proton MR spectra Radiology 187 1 1993 219 227
23. J.R. Moffett, M.A. Namboodiri, C.B. Cangro, and J.H. Neale Immunohistochemical localization of N-acetylaspartate in rat NeuroReport 2 3 1991 131 134
24. J.W. Olney, and N.B. Farber Glutamate receptor dysfunction and schizophrenia Archives of General Psychiatry 52 12 1995 998 1007
25. J.W. Pettegrew, M.S. Keshavan, K. Panchalingam, S. Strychor, D.B. Kaplan, M.G. Tretta, and M. Allen Alterations in brain high-energy phosphate and membrane phospholipid metabolism in first-episode, drug-naive schizophrenics. A pilot study of the dorsal prefrontal cortex by in vivo phosphorus 31 nuclear magnetic resonance spectroscopy Archives of General Psychiatry 48 6 1991 563 568
26. A. Pfefferbaum, E.V. Sullivan, M. Hedehus, M. Moseley, and K.O. Lim Brain gray and white matter transverse relaxation time in schizophrenia Psychiatry Research: Neuroimaging 91 2 1999 93 100
27. 31P chemical shift imaging study of medicated schizophrenic patients and healthy controls Biological Psychiatry 45 6 1999 687 693
28. B.D. Ross, S. Bluml, R. Cowan, E. Danielsen, N. Farrow, and J. Tan In vivo MR spectroscopy of human dementia Neuroimaging Clinics of North America 8 1998 809 822
29. D.L. Rothman, N.R. Sibson, F. Hyder, J. Shen, K.L. Behar, and R.G. Shulman In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate-glutamine neurotransmitter cycle and functional neuroenergetics Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 354 1387 1999 1165 1177
30. 1H MR spectra Magnetic Resonance in Medicine 34 1 1995 17 24
31. J.A. Stanley, P.C. Williamson, D.J. Drost, R.J. Rylett, T.J. Carr, A. Malla, and R.T. Thompson An in vivo proton magnetic resonance spectroscopy study of schizophrenia patients Schizophrenia Bulletin 22 4 1996 597 609
32. J.A. Stanley, J.W. Pettegrew, and M.S. Keshavan Magnetic resonance spectroscopy in schizophrenia: methodological issues and findings-part I Biological Psychiatry 48 5 2000 357 368
33. J. Théberge, D.J. Drost, P.C. Williamson, R. Bartha, A.K. Malla, Y. Al-Semaan, R.W.J. Neufeld, and R.S. Menon 4.0 Tesla Measurements of N-acetylaspartate, Glutamate and Glutamine in the Anterior Cingulate and Thalamus of Schizophrenic Patients Pre- and Post-Treatment. (Abstract #1015) Proceedings of the International Society of Magnetic Resonance in Medicine Ninth Meeting, Glasgow, Scotland, UK 2001
34. J. Théberge, R. Bartha, D.J. Drost, R.S. Menon, A. Malla, J. Takhar, R.W. Neufeld, J. Rogers, W. Pavlosky, B. Schaefer, M. Densmore, Y. Al-Semaan, and P.C. Williamson Glutamate and glutamine measured with 4.0 T proton MRS in never-treated patients with schizophrenia and healthy volunteers American Journal of Psychiatry 159 11 2002 1944 1946
35. J. Théberge, P.C. Williamson, R. Bartha, R.S. Menon, R.W.J. Neufeld, A.K. Malla, J. Takhar, Y. Al-Semaan, and D.J. Drost A 4.0 Tesla Proton Spectroscopy Study of First Episode and Chronic Schizophrenic Patients. (Abstract #700) Proceedings of the International Society of Magnetic Resonance in Medicine Tenth Meeting, Honolulu, HI 2002
36. J. Théberge, Y. Al-Semaan, P.C. Williamson, R.S. Menon, R.W.J. Neufeld, B.A. Schaefer, M. Densmore, and D.J. Drost Glutamate and glutamine in the anterior cingulate and thalamus of chronic medicated schizophrenic patients and healthy controls using proton magnetic resonance spectroscopy at 4.0 Tesla American Journal of Psychiatry 160 12 2003 2231 2233
37. D.R. Weinberger, and R.K. McClure Neurotoxicity, neuroplasticity, and magnetic resonance imaging morphometry: what is happening in the schizophrenic brain? Archives of General Psychiatry 59 6 2002 553 558
38. 31P Magnetic resonance spectroscopy in the assessment of brain phospholipid metabolism in schizophrenia M. Peet I. Glen D.F. Horrobin Phospholipid Spectrum Disorder in Psychiatry 1999 Marius Press Carnforth, UK 45 55