Induction of hepatocyte proliferation by retinoic acid

Carcinogenesis

Volumn 25, Issue 11, 2004, Pages 2061-2066

  Ledda Columbano, G M ^a   Pibiri, M ^a   Molotzu, F ^a   Cossu, C ^a   Sanna, L ^a   Simbula, G ^a   Perra, A ^a   Columbano, A ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; BROXURIDINE; CYCLIN A; CYCLIN D1; CYCLIN E; DNA; PROTEIN P107; RETINOBLASTOMA PROTEIN; RETINOIC ACID; STEROID RECEPTOR; THYROID HORMONE RECEPTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CELL CYCLE S PHASE; CELL DEATH; CELL KINETICS; CELL LABELING; CELL PROLIFERATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DNA CONTENT; DNA SYNTHESIS; FEMALE; HISTOLOGY; LIVER CARCINOGENESIS; LIVER CELL; LIVER INJURY; LIVER REGENERATION; MITOGENESIS; MITOSIS INDEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; VITAMIN SUPPLEMENTATION;

ANIMALS; BROMODEOXYURIDINE; CELL CYCLE; CELL DIVISION; DIETARY SUPPLEMENTS; FEMALE; HEPATOCYTES; KINETICS; MICE; RATS; TRETINOIN;

EID: 8844241477     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh221     Document Type: Article

References (39)

1. Bollag,W. (1983) Vitamin A and retinoids: from nutrition to pharmacotherapy in dermatology and oncology. Lancet, 1, 860-863.
2. Ellis,C.N. and Voorhes,J.J. (1987) Eretrinate therapy. A. J. Am. Acad. Dermatol., 16, 267-291.
3. Giguere,V., Ong,E., Segui,P. and Evans,R.M. (1987) Identification of a receptor for the morphogen retinoic acid. Nature 330, 624-629.
4. Brand,N., Petkocic,M., Krust,A., Chambon,P., de The,H., Marchio,A., Tiollais,P. and Dejan,A. (1988) Identification of a second human retinoic acid receptor. Nature, 332, 850-853.
5. Krust,A., Kastener,P., Petkoviv,M., Kastner,P. and Chambon,P. (1989) A third human retinoic receptor, hRARg. Proc. Natl Acad. Sci. USA, 86, 5310-5314.
6. Zelent,A., Krust,A., Petkovic,M., Kastner,P. and Chambon,P. (1989) Cloning of murine a and b retinoid acid receptors and a novel receptor g predominantly expressed in skin. Nature, 339, 714-717.
7. Mangelsdorf,D.J., Ong,E., Dyck,J.A. and Evans,R.M. (1990) Nuclear receptor that identifies a novel retinoic acid response pathway. Nature, 345, 224-229.
8. Leid,M., Kastner,P., Lyons,R. et al. (1992) Purification, cloning and RXR identity of the HeLa cell factor with which RAR and TR heterodimerizes to bind target sequences efficiently. Cell 68, 377-395.
9. Mangelsdorf,D.J., Bormeyer,U., Heyman,R.A., Zhou,J.Y., Ong,E., Oro,A.E., Kakizuka,A. and Evans,R.M. (1992) Characterization of three RXR genes that mediate the action of cis-retinoic acid. Genes Dev., 6, 329-344.
10. Xiao,J.H., Durand,B., Chambon,P. and Voorhes,J.J. (1995) Endogenous retinoic acid receptor (RAR)-retinoid X receptor (RXR) heterodimers are the major functional forms regulating retinoid-responsive elements in adult human keratinocytes. Binding of ligands to RAR only is sufficient for RAR-RXR heterodimers to confer ligand-dependent activation of hRAR beta2/RARE (DR5). J. Biol. Chem. 270, 3001-3011.
11. Bollag,W. (1971) Effects of vitamin A on transplanted and chemically induced tumors. Cancer Chemother. Rep., 55, 53-58.
12. Smith,M.A., Parkinson,D.R., Cheson,B.D. and Friedman,M.A. (1992) Retinoids in cancer therapy. J. Clin. Oncol., 10, 839-864.
13. Lacroix,A., Doskas,C. and Bhat,P. (1990) Inhibition of growth of established N-methyl-N-nitrosourea-induced mammary cancer in rats by retinoic acid and ovariectomy. Cancer Res., 50, 5731-5734.
14. Ozeki,A. and Tsukamoto,I. (1999) Retinoic acid represses the expression of c-fos and c-jun and induced apoptosis in regenerating rat liver after partial hepatectomy. Biochim. Biophys. Acta, 1450 308-319.
15. Tamura,K., Nakae,D., Horiguchi,K. et al. (1997) Inhibition by N-(4-hydroxyphenyl)retinamide and all-trans-retinoic acid of exogenous and endogenous development of putative preneoplastic glutathione S-transferase placental form-positive lesions in rat liver. Carcinogenesis, 18, 2133-2141.
16. McCormick,D.L., Hollister,J.L., Bagg,B.J. and Long,R.E. (1990) Enhancement of murine hepatocarcinogenesis by all-trans retinoic acid and two synthetic retinamides. Carcinogenesis, 11, 1605-1609.
17. Short,J., Brown,R.F., Husakova,A., Gilbertson,J.R., Zemel,R. and Lieberman,I. (1972) Induction of deoxyribonucleic acid synthesis in the liver of intact animal. J. Biol. Chem., 247, 1757-1766.
18. Francavilla,A., Carr,B.I., Azzarone,A., Polimeno,L., Wang,Z., Van Diehe,D.H., Subbotin,V., Prelich,J.G. and Starzl,T.E. (1994) Hepatocyte proliferation and gene expression induced by triiodothyronine in vivo and in vitro. Hepatology, 20, 1237-1241.
19. Rao,M.S. and Reddy,J.K. (1987) Peroxisome proliferators and hepatocarcinogenesis. Carcinogenesis, 8, 631-636.
20. Marsman,D.S., Cattley,R.C., Conway,G. and Popp,J.A. (1988) Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xilidino)-2-pirimidynilthio]acetic acid (WY14643) in rats. Cancer Res., 48, 6739-6744.
21. Ledda-Columbano,G.M. and Columbano,A. (2003) Mitogenesis by ligands of nuclear receptors: an attractive model for the study of the molecular mechanisms implicated in liver growth. Cell Death Differ. 10, S19-S21.
22. Ledda-Columbano,G.M., Pibiri,M., Loi,R., Perra,A., Shinozuka,H. and Columbano,A. (2000) Early increase in cyclin D1 expression and accelerated entry of mouse hepatocytes into S phase after administration of the mitogen 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene. Am. J. Pathol., 56, 91-97.
23. Pibiri,M., Ledda-Columbano,G.M., Cossu,C., Simbula,G., Menegazzi,M., Shinozuka,H. and Columbano,A. (2001) Cyclin D1 is an early target in hepatocyte proliferation induced by thyroid hormone (T3). FASEB J., 15, 1006-1013.
24. Ledda-Columbano,G.M., Curto,M., Piga,R. et al. (1998) In vivo hepatocyte proliferation is inducible through a TNF and IL-6-independent pathway. Oncogene, 17, 1039-1044.
25. Michalopoulos,G.K. and DeFrances,M.C. (1997) Liver regeneration. Science, 276, 60-66.
26. Yamada,Y., Kirillova,I., Peschon,J.J. and Fausto,N. (1997) Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor. Proc. Natl Acad. Sci. USA, 94, 1441-1446.
27. Cressmann,D.E., Greenbaum,L.E., DeAngelis,R.A., Ciliberto,G., Furth,E.E., Poli,V. and Taub,R. (1996) Liver failure and defective hepatocyte regeneration in interleukin-6 deficient mice. Science, 274, 1379-1383.
28. Akerman,P., Cote,P., Yang,S.-Q., McClain,C., Nelson,S., Bagby,G.J. and Diehl,A.M. (1992) Antibodies to tumor necrosis factor-α inhibit liver regeneration after partial hepatectomy. Am. J. Physiol. 263, G579-G585.
29. Columbano,A. and Shinozuka,H. (1996) Liver regeneration versus direct hyperplasia. FASEB J., 10, 1118-1128.
30. Burton,K. (1956) A study of the conditions and mechanisms of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem. J., 62, 315-323.
31. Bradford,M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
32. Columbano,A., Ledda-Columbano,G.M., Coni,P., Liguori,C., Santa Cruz,G. and Pani,P. (1984) Occurrence of cell death (apoptosis) during the involution of liver hyperplasia. Lab. Invest., 52, 670-675.
33. Herwig,S. and Strauss,M. (1997) The retinoblastoma protein: a master regulator of cell cycle, differentiation and apoptosis. Eur. J. Biochem., 15, 581-601.
34. Sherr,C.J. (1996) Cancer cell cycles. Science, 274 1672-1677.
35. Zhu,W.-Y., Jones,C.S., Kiss,A., Matsukuma,K., Amin,S. and De Luca,L.M. (1997) Retinoic acid inhibition of cell cycle progression in MCF-7 human breast cancer cells. Exp. Cell. Res., 234, 293-299.
36. Lancillotti,F., Darwiche,N., Celli,G. and De Luca,L.M. (1992) Retinoid status and the control of keratin expression and adhesion during the histogenesis of squamous metaplasia of tracheal epithelium. Cancer Res., 52, 6144-6152.
37. De Luca,L.M., Brugh,M. and Silverman-Jones,C.S. (1984) Retinyl palmitate, retinyl phosphate, dolichyl phosphate of postnuclear membrane fraction from hepatoma, host liver and regenerating liver: marginal vitamin A status of hepatoma tissue. Cancer Res., 44 224-232.
38. Enomoto,K. and Farber,E. (1982) Kinetics of phenotypic maturation of remodelling of hyperplastic nodules during liver carcinogenesis. Cancer Res., 42, 2330-2335.
39. Ledda-Columbano,G.M., Perra,A., Loi,R., Shinozuka,H. and Columbano,A. (2000) Cell proliferation induced by triiodothyronine in rat liver is associated with nodule regression and reduction of hepatocellular carcinomas. Cancer Res., 60, 603-609.