Design of FAD-binding peptide using a combinatorial α-helix peptide library

Chemistry Letters

Volumn 33, Issue 8, 2004, Pages 978-979

  Sakamoto, Seiji ^a   Okano, Ippei ^a   Kudo, Kazuaki ^a  

^a INSTITUTE OF INDUSTRIAL SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; BENZOIC ACID DERIVATIVE; BINDING PROTEIN; BORON DERIVATIVE; FLAVINE ADENINE NUCLEOTIDE; LYSINE; PEPTIDE LIBRARY;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN MODIFICATION; PROTEIN STRUCTURE;

EID: 8844239268     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2004.978     Document Type: Article

References (9)

1. "Chemistry and biochemistry of flavoenzymes," ed. by F. Muller, CRC Press (1991-1992), Vol. 1-3.
2. S. Sakamoto, H. Aoyagi, N. Nakashima, and H. Mihara, J. Chem. Soc., Perkin Trans. 2, 1996, 2319.
3. R. E. Sharp, C. C. Moser, F. Rabanal, and P. L. Dutton, Proc. Natl. Acad. Sci. U.S.A., 95, 10465 (1998).
4. S. M. Butterfield, C. M. Goodman, V. M. Rotello, and M. L. Waters, Angew. Chem., Int. Ed., 43, 724 (2004).
5. S. Marqusee and R. L. Baldwin, Proc. Natl. Acad. Sci. U.S.A., 84, 8898 (1984).
6. I. Hamachi, Y. Tajiri, T. Nagase, and S. Shinkai, Chem. - Eur. J., 3, 1025 (1997).
7. 8 side-chain using 2-(1H-benzotriazole-1-yl)-1,1,3,3- tetramethyluronium hexafluorophosphate, 1-hydroxybenzotriazole hydrate, and diisopropylethylamine as coupling reagents.
8. Peptides were identified by MALDI-TOFMS and amino acid analysis. Analytical size-exclusion chromatography using natural globular proteins as standards suggest that the peptides existed as monomeric forms under the experimental conditions.
9. J. M. Scholtz, Q. Hong, E. J. York, J. M. Stewart, and R. L. Baldwin, Biopolymers, 31, 1463 (1991).