Determination of MK-0767 enantiomers in human plasma by normal phase LC-MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 813, Issue 1-2, 2004, Pages 95-102

  Yan, Kerri X ^a   Song, Hengchang ^a   Lo, Man Wai ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Chiral separation; Diabetes; Dual PPAR; LC MS MS; Liquid liquid extraction; MK 0767 (KRP 297); Normal phase; Thiazolidinediones

Indexed keywords

CHIRALS; ENANTIOMERS; HUMAN PLASMA; REAGENTS;

ATMOSPHERIC PRESSURE; CONCENTRATION (PROCESS);

CHROMATOGRAPHY;

5 (2,4 DIOXO 5 THIAZOLIDINYLMETHYL) 2 METHOXY N [4 (TRIFLUOROMETHYL)BENZYL] BENZAMIDE; 5 (2,4 DIOXO 5 THIAZOLIDINYLMETHYL) 2 METHOXY N [4 (TRIFLUOROMETHYL)BENZYL]BENZAMIDE; UNCLASSIFIED DRUG;

ACCURACY; ANALYTIC METHOD; ARTICLE; DRUG DETERMINATION; ENANTIOMER; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; SAMPLING; VALIDATION PROCESS;

CHROMATOGRAPHY, LIQUID; HUMANS; MASS SPECTROMETRY; REFERENCE STANDARDS; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM; THIAZOLES;

EID: 8844238398     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2004.09.016     Document Type: Article

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