Direct chiral separation of troglitazone stereoisomers using reversed-phase high-performance liquid chromatography

Journal of Pharmaceutical and Biomedical Analysis

Volumn 30, Issue 3, 2002, Pages 823-836

  Suzuki, Nobuyuki ^a   Takemura, Akira ^a   Miyamoto, Akifumi ^a   Yoshioka, Takao ^a   Tsutsumi, Shinya ^a   Kawasaki, Takao ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Anti diabetic drug; Chiral column; Chiral separation; Reversed phase LC; Troglitazone

Indexed keywords

ACETIC ACID; METHANOL; ROY 1585; ROY 1586; ROY 1587; ROY 1588; THIAZOLIDINE DERIVATIVE; TROGLITAZONE; UNCLASSIFIED DRUG;

ARTICLE; CALIBRATION; CHIRALITY; CORRELATION COEFFICIENT; DIASTEREOISOMER; DRUG FORMULATION; DRUG MANUFACTURE; DRUG SCREENING; DRUG STABILITY; FLOW RATE; ISOMER; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STEREOISOMERISM; VALIDATION PROCESS;

CHEMISTRY, PHARMACEUTICAL; CHROMANS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM; THIAZOLES; THIAZOLIDINEDIONES;

EID: 0037201663     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(02)00391-6     Document Type: Article

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