Comparison of the antinociceptive activity of two new NO-releasing derivatives of the NSAID S-ketoprofen in rats

British Journal of Pharmacology

Volumn 143, Issue 5, 2004, Pages 533-540

  Gaitan, Gema ^a   Javier Ahuir, F ^a   Del Soldato, Piero ^b   Herrero, Juan F ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b NicOx SA   (France)

Author keywords

Cyclooxygenase; Inflammation; Single motor unit; Spinal cord; Wind up; Withdrawal reflex

Indexed keywords

KETOPROFEN; NITRIC OXIDE; NITRIC OXIDE DONOR; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN SYNTHASE;

ALLODYNIA; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; HYPERALGESIA; INFLAMMATION; MALE; MECHANICAL STIMULATION; MOTOR UNIT; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD; WITHDRAWAL REFLEX;

ANALGESICS; ANESTHESIA; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BEHAVIOR, ANIMAL; BLOOD PRESSURE; CARRAGEENAN; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; ELECTRIC STIMULATION; KETOPROFEN; MALE; MOTOR NEURONS; MUSCLE, SKELETAL; NITRIC OXIDE; PAIN MEASUREMENT; PHYSICAL STIMULATION; RATS; RATS, WISTAR; REFLEX;

EID: 8744286419     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705958     Document Type: Article

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