Retrospective analysis of the clinical course of 12 children given the diagnosis essential thrombocythemia;Retrospektive analyse des klinischen verlaufs bei 12 kindern mit der verdachtsdiagnose einer essenziellen thrombozythämie

Klinische Padiatrie

Volumn 216, Issue 6, 2004, Pages 349-355

  Kratz, Christian P ^a   Abd El Monheim, A ^a   Manke, E M ^a   Rister, M ^b   Rogge, T ^a   Niemeyer, C M ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b Stadtisches Klinikum Kemperhof   (Germany)

Author keywords

Essential thrombocythemia; Myeloproliferative disorder; Thrombocytosis

Indexed keywords

ACETYLSALICYLIC ACID; ANAGRELIDE; HYDROXYUREA;

ABDOMINAL PAIN; ADOLESCENT; ARTICLE; BLEEDING; BONE MARROW EXAMINATION; CHILD; CLINICAL ARTICLE; CONCENTRATION LOSS; CONTROLLED STUDY; CYTOGENETICS; DISEASE COURSE; FATIGUE; FOLLOW UP; HUMAN; INCIDENTAL FINDING; MYELOID METAPLASIA; RETROSPECTIVE STUDY; SYNCOPE; THROMBOCYTE COUNT; THROMBOCYTHEMIA; TREATMENT OUTCOME;

ADOLESCENT; AGE FACTORS; BONE MARROW EXAMINATION; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MYELOPROLIFERATIVE DISORDERS; PLATELET COUNT; RETROSPECTIVE STUDIES; THROMBOCYTHEMIA, HEMORRHAGIC; THROMBOCYTOSIS; TIME FACTORS;

EID: 8744249273     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-832356     Document Type: Article

References (29)

1. Allen AJ, Gale RE, Harrison CN, Machin SJ, Linch DC. Lack of pathogenic mutations in the 5′-untranslated region of the thrombopoietin gene in patients with non-familial essential thrombocythaemia. Eur J Haematol 2001; 67: 232-237
2. Ballmaier M, Germeshausen M, Schulze H, Cherkaoui K, Lang S, Gaudig A, Krukemeier S, Eilers M, Strauss G, Weite K. c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia. Blood 2001; 97: 139-146
3. Cario H, Schwarz K, Debatin KM, Kohne E. Congenital erythrocytosis and polycythemia vera in childhood and adolescence. Klin Padiatr 2004; 216: 157-162
4. Chiusolo P, La Barbera EO, Laurenti L, Piccirillo N, Sora F, Giordano G, Urbano R, Mazzucconi MG, De Stefano V, Leone G, Sica S. Clonal hemopoiesis and risk of thrombosis in young female patients with essential thrombocythemia. Exp Hematol 2001; 29: 670-676
5. Cilloni D, Carturan S, Gottardi E, Messa F, Fava M, Defilippi I, Arruga F, Saglio G. Usefulness of the quantitative assessment of PRV-1 gene expression for the diagnosis of polycythemia vera and essential thrombocythemia patients. Blood 2004; 103: 2428
6. Cortelazzo S, Finazzi G, Ruggeri M, Vestri O, Galli M, Rodeghiero F, Barbui T. Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis. N Engl J Med 1995; 332: 1132-1136
7. Ding J, Komatsu H, Wakita A, Kato-Uranishi M, Ito M, Satoh A, Tsuboi K, Nitta M, Miyazaki H, Iida S, Ueda R. Familial essential thrombocythemia associated with a dominant-positive activating mutation of the c-MPL gene, which encodes for the receptor for thrombopoietin. Blood 2004; 103: 4198-4200
8. Dror Y, Blanchette VS. Essential thrombocythaemia in children. Br J Haematol 1999; 107: 691-698
9. El Kassar N, Hetet G, Briere J, Grandchamp B. Clonality analysis of hematopoiesis in essential thrombocythemia: advantages of studying Tlymphocytes and platelets. Blood 1997; 89: 128-134
10. El Kassar N, Hetet G, Briere J, Grandchamp B. Clonality analysis of hematopoiesis and thrombopoietin levels in patients with essential thrombocythemia. Leuk Lymphoma 1998; 30: 181-188
11. Fruchtman SM. Treatment paradigms in the management of myeloproliferative disorders. Semin Hematol 2004; 41: 18-22
12. Fruchtman SM, Petitt RM, Gilbert HS. Anagrelide therapy significantly reduces disease related symptoms in patients with myeloproliferative symptoms. Blood 2003; 102: 32a
13. Gandini D, Allen AJ, Nash MJ, Linch DC, Gale RE. No mutations in the gata-1 gene detected in patients with acquired essential thrombocythemia. Haematologica 2004; 89: 613-615
14. Ghilardi N, Wiestner A, Kikuchi M, Ohsaka A, Skoda RC. Hereditary thrombocythaemia in a Japanese family is caused by a novel point mutation in the thrombopoietin gene. Br J Haematol 1999; 107: 310-316
15. Griesshammer M, Klippel S, Strunck E, Temerinac S, Mohr U, Heimpel H, Pahl HL. PRV-1 mRNA expression discriminates two types of essential thrombocythemia. Ann Hematol 2004; 83: 364-370
16. Harrison CN. Current trends in essential thrombocythaemia. Br J Haematol 2002; 117: 796-808
17. Hasle H. Incidence of essential thrombocythaemia in children. Br J Haematol 2000; 110: 751
18. Imbert M, Vardimann JW, Pierre R, Brunning RD, Thiele J, Flandrin G. Essential thrombocythaemia. In: Jaffe ES, Harris NL, Stein H, Vardiman JW (Hrsg). World Health Organization Classification of Tumours. IARC Press, Lyon 2001
19. Kondo T, Okabe M, Sanada M, Kurosawa M, Suzuki S, Kobayashi M, Hosokawa M, Asaka M. Familial essential thrombocythemia associated with one-base deletion in the 5′-untranslated region of the thrombo-poietin gene. Blood 1998; 92: 1091-1096
20. McIntyre KJ, Hoagland HC, Silverstein MN, Petitt RM. Essential thrombocythemia in young adults. Mayo Clin Proc 1991; 66: 149-154
21. Mesa RA, Silverstein MN, Jacobsen SJ, Wollan PC, Tefferi A. Population-based incidence and survival figures in essential thrombocythemia and agnogenic myeloid metaplasia: an Olmsted County Study, 1976-1995. Am J Hematol 1999; 61: 10-15
22. Murphy S, Peterson P, Hand H, Laszlo J. Experience of the Polycythemia Vera Study Group with essential thrombocythemia: a final report on diagnostic criteria, survival, and leukemic transition by treatment. Semin Hematol 1997; 34: 29-39
23. Prchal JF, Finazzi G, Pastore YD, Chintagumpala MM, Prchal JT. Essential Thrombocythemia in Children. Blood 2003; 102: 918a-918a
24. Randi ML, Putti MC, Fabris F, Sainati L, Zanesco L, Girolami A. Features of essential thrombocythaemia in childhood: a study of five children. Br J Haematol 2000; 108: 86-89
25. Schafer AI. Thrombocytosis. N Engl J Med 2004; 350: 1211-1219
26. Scherer S, Ferrari R, Rister M. Treatment of essential thrombocythemia in childhood. Pediatr Hematol Oncol 2003; 20: 361-365
27. Solberg LA Jr. Therapeutic options for essential thrombocythemia and polycythemia vera. Semin Oncol 2002; 29: 10-15
28. Taksin AL, Couedic JP, Dusanter-Fourt I, Masse A, Giraudier S, Katz A, Wendung F, Vainchenker W, Casadevall N, Debili N. Autonomous megakaryocyte growth in essential thrombocythemia and idiopathic myelofibrosis is not related to a c-mpl mutation or to an autocrine stimulation by Mpl-L. Blood 1999; 93: 125-139
29. Wiestner A, Schlemper RJ, van der Maas AP, Skoda RC. An activating splice donor mutation in the thrombopoietin gene causes hereditary thrombocythaemia. Nat Genet 1998; 18: 49-52