Insulin resistance as a programmed response to fetal undernutrition

Diabetologia

Volumn 39, Issue 9, 1996, Pages 1119-1122

  Phillips, D I W ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; FETUS; FETUS DEVELOPMENT; FETUS GROWTH; HUMAN; HYPOTHESIS; INSULIN RESISTANCE; MALNUTRITION; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL;

EID: 0029791898     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00400663     Document Type: Article

References (40)

1. Reaven GM (1988) Role of insulin resistance in human disease. Diabetes 37: 1595-1607
2. Hales CN, Barker DJP, Clark PMS et al. (1991) Fetal and infant growth and impaired glucose tolerance at age 64. BMJ 303: 1019-1022
3. Phipps K, Barker DJP, Hales CN, Fall CHD, Osmond C, Clark PMS (1993) Fetal growth and impaired glucose tolerance in men and women. Diabetologia 36: 225-228
4. Lithell HO, McKeigue PM, Berglund L, Mohsen R, Lithell U-B, Leon DA (1996) Relation of size at birth to non-insulin dependent diabetes and insulin concentrations in men aged 50-60 years. BMJ 312: 406-410
5. Hales CN, Barker DJP (1992) Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia 35: 595-601
6. Phillips DIW, Barker DJP, Hales CN, Hirst S, Osmond C (1994) Thinness at birth and insulin resistance in adult life. Diabetologia 37: 150-154
7. Barker DJP, Hales CN, Fall CHD, Osmond C, Phipps K, Clark PMS (1993) Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 36: 62-67
8. Valdez R, Athens MA, Thompson GH, Bradshaw BS, Stern MP (1994) Birthweight and adult health outcomes in a biethnic population in the USA. Diahetologia 37: 624-631
9. Yajnik CS, Fall CHD, Vaidya U et al. (1995) Fetal growth and glucose and insulin metabolism in four-year-old Indian children. Diabet Med 12: 330-336
10. Fowden AL (1989) The role of insulin in prenatal growth. J Developmental Physiol 12: 173-182
11. Tamemoto H, Kadowaki T, Tobe K et al. (1994) Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1. Nature 372: 182-189
12. Walton A, Hammond J (1938) The maternal effects on growth and conformation in Shirehorse-Shetland pony crosses. Proc Roy Soc Lond 125: 311-335
13. Morton NE (1955) The inheritance of human birth weight. Ann Hum Genet 19: 262-268
14. Carr-Hill R, Campbell DM, Hall MH, Meredith A (1987) Is birth weight determined genetically? BMJ 295: 687-689
15. Ounsted M, Scott A, Ounsted C (1986) Transmission through the female line of a mechanism constraining fetal growth. Ann Human Biol 13: 143-151
16. McCance RA, Widdowson EM (1974) The determinants of growth and form. Proc R Soc Lond 185: 1-17
17. Snow MHL (1989) Effects of genome on fetal size at birth. In: Sharp F, Fraser RB, Milner RDG (eds) Fetal growth. Proc 20th Study Group, RCOG Royal College of Obstetricians and Gynaecologists, London, pp 1-11
18. Winick M, Noble A (1966) Cellular response in rats during malnutrition at various ages. J Nutrition 89: 300-306
19. Lucas A (1991) Programming by early nutrition in man. In: Bock GR, Whelan J (eds) The childhood environment and adult disease. John Wiley, Chichester pp 38-49
20. Jansson T, Persson E (1990) Placental transfer of glucose and amino acids in intrauterine growth retardation: studies with substrate analogues in the awake guinea pig. Pediatr Res 28: 203-208
21. Langley SC, Jackson AA (1994) Increased systolic blood pressure in adult rats induced by fetal exposure to maternal low protein diets. Clin Science 86: 217-222
22. Owens JA, Owens PC, Robinson JS (1989) Experimental fetal growth retardation: metabolic and endocrine aspects. In: Gluckman PD, Johnston BM, Nathanielsz PW (eds) Advances in fetal physiology, Ithaca, N. Y. pp 263-286
23. Economides DL, Nicolaides KH (1990) Metabolic findings in small-for-gestational-age fetuses. Cont Rev Obstet Gynaecol 2: 75-79
24. Economides DL, Crook D, Nicolaides KH (1990) Hypertriglyceridaemia and hypoxaemia in small for gestational age fetuses. Am J Obstet Gynecol 162: 382-386
25. Economides DL, Proudler A, Nicolaides KH (1984) Plasma insulin in appropriate- and small-for-gestational-age fetuses. Am J Obstet Gynecol 160: 1091-1094
26. Phillips DIW (1995) Relation of fetal growth to adult muscle mass and glucose intolerance. Diabet Med 12: 686-690
27. Wootton SA, Murphy JL, Wilson F, Phillips D (1994) Energy expenditure and substrate metabolism after carbohydrate ingestion in relation to fetal growth in women born in Preston. Proc Nutr Soc 53: 174A (Abstract)
28. 31P magnetic resonance spectroscopy, Diabetologia 38: 1205-1212
29. Phillips DIW, McLeish R, Osmond C, Hales CN (1995) Fetal growth and insulin resistance in adult life: role of triglyceride and non-esterified fatty acids. Diabet Med 12: 796-801
30. Phillips DIW, Borthwick AC, Stein C, Taylor R (1996) Fetal growth and insulin resistance in adult life: relationship between glycogen synthase activity in adult skeletal muscle and birth weight. Diabet Med 13: 325-329
31. Desai M, Crowther NJ, Ozanne SE, Lucas A, Hales CN (1995) Adult glucose and lipid metabolism may be programmed during fetal life. Biochem Soc Trans 23: 331-335
32. Plotsky PM, Meaney MJ (1993) Early, postnatal experience alters hypothalamic corticotrophin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in rats. Molec Brain Res 18: 195-200
33. Reul JMHM, Stec I, Wiegers GJ et al. (1994) Prenatal immune challenge alters the hypothalamic-pituitary-adrenocortical axis in adult rats. J Clin Invest 93: 2600-2607
34. Dauncey MJ, Burton KA, White P, et al. (1994) Nutritional regulation of growth hormone receptor gene expression. FASEB J 8: 81-88
35. Zeman FJ, Shrader RE, Allen LH (1973) Persistent effects of maternal protein deficiency in postnatal rats. Nutrition Reports International 7: 421-436
36. Barker DJP, Gluckman PD, Godfrey KM, Harding JE, Owens JA, Robinson JS (1993) Fetal nutrition and cardiovascular disease in adult life. Lancet 341: 938-941
37. Fall CHD, Osmond C, Barker DJP et al. (1995) Fetal and infant growth and cardiovascular risk factors in women. BMJ 310: 428-431
38. McCance DR, Pettitt DJ, Hanson RL, Jacobsson LTH, Knowler WC, Bennett PH (1994) Birth weight and non-insulin dependent diabetes: thrifty genotype, thrifty phenotype, or surviving small baby genotype? BMJ 308: 942-945
39. Robinson SM, Walton RJ, Clark PMS, Barker DJP, Hales CN, Osmond C (1992) The relation of fetal growth to plasma glucose in young men. Diabetologia 35: 444-446
40. Law CM, Gordon GS, Shiell AW, Barker DJP, Hales CN (1995) Thiness at birth and glucose tolerance in seven-year-old children. Diabet Med 12: 24-29