Inhibition of both Trypanosoma brucei bloodstream form and related glycolytic enzymes by a new kolavic acid derivative isolated from Entada abyssinica

Pharmazie

Volumn 59, Issue 11, 2004, Pages 873-875

  Nyasse, Barthelemy ^a   Ngantchou, I ^a   Tchana, E M ^a   Sonke B ^a   Denier, C ^b   Fontaine, C ^c  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b UNIVERSITÉ PAUL SABATIER   (France)

^c UNIVERSITÉ JOSEPH FOURIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENTADA ABYSSINICA EXTRACT; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; KOLAVIC ACID DERIVATIVE; METHYL ESTER 15 KOLAVIC ACID; PLANT EXTRACT; UNCLASSIFIED DRUG;

AFRICA; AFRICAN TRYPANOSOMIASIS; ANTIPROTOZOAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; ENTADA ABYSSINICA; ENZYME INHIBITION; GLYCOLYSIS; IC 50; MEDICINAL PLANT; NONHUMAN; SPECTROSCOPY; TRADITIONAL MEDICINE; TRYPANOSOMA BRUCEI;

ANIMALS; ANTIMALARIALS; ANTIPROTOZOAL AGENTS; DITERPENES; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; GLYCOLYSIS; LEISHMANIA INFANTUM; MAGNETIC RESONANCE SPECTROSCOPY; PHOSPHOFRUCTOKINASES; PLANT BARK; PLANTS, MEDICINAL; PYRUVATE KINASE; TRYPANOSOMA BRUCEI BRUCEI;

EID: 8744239416     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Bohlmann F, Zdero C, Gupta RK, King RM, Robinson H (1980) Diterpenes and tetranorditerpenes from Acritopappus species. Phytochemistry 19: 2695-2705.
2. Cane DE and Sohng JK (1989) Inhibition of glyceraldehyde-3-phosphate dehydrogenase by pentalenolactone: kinetic and mechanistic studies. Arch Biochem Biophys 270: 50-61.
3. Cane DE, Sohng JK (1994) Inhibition of glyceraldehyde-3-phosphate dehydrogenase (GADH) by pentalenolactone. Identification of site alkylation by tetrahydropentalenolactone. Biochemistry 33: 6524-6530.
4. Epner DE, Partin AW, Schalken JA, Issacs JT, Coffey DS (1993) Association of glyceraldehyde-3-phosphate dehydrogenase with cell motility and metastatic potential of rat prostatic adenocarcinoma. Cancer Res 53: 1995-1997.
5. Freiburghaus F, Ogwal EN, Nkunya MHH, Kaminsky R, Brun R (1996) In vitro antitrypanosomal activity of African plants used in traditional medicine in Uganda to treat sleeping sickness. Trop. Med. Int. Health 1: 765-771.
6. Hannaert V, Opperdoes FR, Michels PAM (1995) Protein Expression and Purification 3: 244.
7. Iten M, Matovu E, Brun R, Kaminsky R (1995) Innate lack of susceptibility of Ugandan Trypanosoma brucei rhodesiense to DL-α-difluoromethylornithine (DFMO). Trop Med Parasitol 46: 190-195.
8. Kuzoe FAS (1993) Current situation of African trypanosomiasis. Acta Tropica 54: 153-162.
9. Ladame S, Bardet M, Périé J, Willson M (2001) Selective inhibition of Trypanosoma brucei GAPDH by 1,3-bisphospho-D-glyceric acid (1,3-diPG) analogues. Bioorg Med Chem 9: 773-783.
10. Lambeir AM, Loiseau AM, Kuntz DA, Vellieux FM, Michels PAM, Opperdoes FR (1991) The cytosolic and glycosomal glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma brucei: Kinetic properties and comparison with homologous enzymes. Eur J Biochem 198: 429-435.
11. Legros D, Evans S, Maiso F, Enyaru JCK, Mbulamberi D (1999) Risk factors for treatment failure after melarsoprol for T.b. gambiense Trypanosomiasis in Uganda. Trans R Soc Trop Med Hyg 93: 439-442.
12. Miscra R, Pandey RC, Dev S (1964) The chemistry of the oleo resin from Hardwickia pinnata: a series of new diterpenoids. Tetrahedron Lett 49: 3751-3759.
13. Nyasse B, Nkwengoua E, Sondengam B, Denier C, Willson M (2002) Modified berberine and protoberberines from Enantia chlorantha as potential inhibitors of Trypanosoma brucei. Pharmazie 57: 358-361.
14. Pépin J, Milord F (1994) The treatment of human African trypanosomiasis. Adv Parasitol 33: 1-47.
15. Richomme P, Godet MC, Foussard F, Toupet L, Sévenet T, Bruneton J (1991). Planta Med 57: 552-554.
16. Sepulveda-Boza S, Cassels BK (1996) Plant metabolites active against Trypanosoma cruzi. Planta Med 62: 98-139.
17. Schulze H, Schuyler A, Stuber D, Dobeli H, Langen H, Huber G (1993) Rat brain glyceraldehyde-3-phosphate dehydrogenase interacts with the recombinant cytoplasmic domain of Alzheimer β-amyloid precursor protein. J Neurochem 60: 1915-1922.
18. Souza DHF, Garratt RC, Araujo APU, Guimaraes BG, Jesus WDP, Michels PAM, Hannaert V, Oliva G (1998) Trypanosoma cruzi glycosomal glyceraldehyde-3- phosphate dehydrogenase: structure, catalytic mechanism and targeted inhibitor design. FEBS Lett 424: 131-135.
19. Stanghellini A, Josenando T (2001) The situation of sleeping sickness in Angola: a calamity. Trop Med Int Health 6: 330-334.
20. Sunaga K, Takahashi H, Chuang D.-M, Ishitani R (1995) Glyceraldehyde-3-phosphate dehydrogenase is over-expressed during apoptotic death of neuronal cultures and is recognized by a monoclonal antibody against amyloid plaques from Alzheimer brain. Neurosci Lett 200: 133-136.
21. Van Nieuwenhove S (1992) Advances in sleeping sickness therapy. Ann Soc Belge Méd Trop 83 (Suppl 1): 7-12.
22. WHO (2001) http://www.who.int/emc-documents/surveillance/docs/ whocdscsrisr2001.htm
23. WHO (1998) La trypanosomiase africaine: lutte et surveillance. Rapport d'un comité d'experts de l'OMS. Série de rapports techniques no 881. Geneva: WHO
24. WHO (2000) The World Health Report 2000: Health Systems, Improving Performance.
25. Willson M, Lauth N, Périé J, Callens M, Opperdoes FR (1994) Inhibition of glyceraldehyde-3-phosphate dehydrogenase by phosphorylated epoxides and α-enones. Biochemistry 33: 214-220.
26. Wright CW, Phillipson JD (1990) Natural products and the development of selective antiprotozoal drugs. Phytother Res 4: 127-137.