Inhibition of COX isoforms by nutraceuticals

Journal of Herbal Pharmacotherapy

Volumn 4, Issue 2, 2004, Pages 11-18

  Seaver, Ben ^a   Smith, Jerry Robert ^a  

^a UNIVERSITY OF MONTANA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMENTOFLAVONE; BERBERINE; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; GLUCOSAMINE; IBUPROFEN; INDOMETACIN; IPRIFLAVONE; MAGNESIUM DERIVATIVE; MAGNESIUM SALVINOLIC ACID; MSV 60; NAPROXEN; NEXRUTINE; PANAX NOTOGINSENG EXTRACT; PROSTAGLANDIN SYNTHASE; RESVERATROL; ROFECOXIB; RUSCUS EXTRACT; SALVIA MILTIORRHIZA EXTRACT; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL PROTECTION; CONCENTRATION RESPONSE; ENZYME INHIBITION; HUMAN; KIDNEY INJURY; MINIMUM INHIBITORY CONCENTRATION; MULTIPLE REGRESSION; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; STOMACH ULCER;

BIFLAVONOIDS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; HUMANS; INFLAMMATION; ISOENZYMES; ISOFLAVONES; MEMBRANE PROTEINS; NEOPLASMS; PLANT EXTRACTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RUSCUS; STILBENES;

EID: 8744230804     PISSN: 15228940     EISSN: None     Source Type: Journal    
DOI: 10.1300/J157v04n02_02     Document Type: Article

References (7)

1. Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nat New Biol. 1971; 231:232-235.
2. Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10th Ed. (McGraw-Hill), 2001, Chapter 27: 687-731.
3. Poulev, A. et al. The determination of salicylates in Gaultheria procumbens for use as a natural aspirin alternative. Journal of Nutraceuticals, Functional and Medicinal Foods. 2003; 4:40-52.
4. Marnett, LJ et al. COX-2: A target for colon cancer prevention. Annual Review of Pharmacology and Toxicology. 2002; 42:55-80.
5. Hawkey, CJ. COX-2 inhibitors. Lancet. 1999; 353:307-314.
6. Leady, MA et al. Survey of alternative supplement use within a hospitalized population. Hospital Pharmacy. 2002; 37(12):1295-1300.
7. Holton, T. NIH pharmacists warn consumers about herb safety. Drug Topics 2000; 144:59.