Association of the tumor necrosis factor alpha gene polymorphism with susceptibility and clinical-immunological findings of systemic lupus erythematosus

Asian Pacific Journal of Allergy and Immunology

Volumn 22, Issue 2-3, 2004, Pages 159-163

  Azizah, M R ^a   Kuak, S H ^a   Ainol, S S ^b   Rahim, M N ^c   Normaznah, Y ^a   Norella, K ^d  

^a INSTITUTE FOR MEDICAL RESEARCH   (Malaysia)

^b HOSPITAL PULAU PINANG   (Malaysia)

^c Universiti Selangor   (Malaysia)

^d UNIVERSITI KEBANGSAAN MALAYSIA MEDICAL CENTER   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; LA ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD DONOR; CENTRAL NERVOUS SYSTEM DISEASE; CHINESE; CLINICAL IMMUNOLOGY; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ETHNOLOGY; FEMALE; FOLLOW UP; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC CODE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MALAYSIA; MALE; MEDICAL RECORD; POLYMERASE CHAIN REACTION; PROTEIN FUNCTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; STATISTICAL SIGNIFICANCE; SYSTEMIC LUPUS ERYTHEMATOSUS; UNIVERSITY HOSPITAL;

ADULT; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALAYSIA; MALE; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TUMOR NECROSIS FACTOR-ALPHA;

EID: 8644267523     PISSN: 0125877X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Hochberg MC. The application of genetic epidemiology to systemic lupus erythematosus. J Rheumatol 1987; 14: 867-9.
2. Deapen DM, Escalante A, Weinrib L, et al. A revised estimate of twin concordance in systemic lupus erythematosus. Arthritis Rheum 1992; 35: 311-8.
3. Wilson AG, Giovane VS, Blakemore AIF, Duff GW. Single base polymorphism in the human tumour necrosis factor alpha (TNFα) gene detectable by Nco 1 restriction of PCR product. Human Mol Genet 1992; 1: 353.
4. Wilson AG, Gordon C, Griovane VS, et al. A genetic association between systemic lupus erythematosus and tumor necrosis factor alpha. Eur J Immunol 1994; 24: 191-5.
5. Wilson AG, de Vries N, Pociot F, Giovane VS, van der Putte LBA, Duff GW. An allelic polymorphism within the human tumor necrosis factor a promoter region is strongly associated with HLA-A1, -B8 and -DR3 alleles. J Exp Med 1994; 177: 557-60.
6. Tomita Y, Hashimoto S, Yamagami K, Sawada S, Horie T. Restriction fragment length polymorphism analysis in the TNF genes of patients with systemic lupus erythematosus. Clin Exp Rheumatol 1993; 11: 533-6.
7. Tan EM, Cohen AS, Fries JF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271-7.
8. Pociot F, Briant L, Jongeneel CV, et al. Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNFand TNF β by human mononuclear cells: a possible link to insulin-independent diabetes mellitus. Eur J Immunol 1993; 23: 224-30.
9. Elliott MJ, Maini RN, Feldmann M et al. Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor α. Arthritis Rheum 1993; 36: 1681-90.
10. Jacob CO, Fronek Z, Lewis GD, Koo M, Hansen JA, McDeviitt HO. Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci USA 1990; 87: 1233-7.
11. Jacob CO, McDevitt HO. Tumour necrosis factor α in murine autoimmune "lupus" nephritis. Nature 1988; 331: 56-8.
12. Abraham LJ, French MA, Dawkins RL. Polymorphic MHC ancestral haplotypes affect the activity of tumour necrosis factor alpha. Clin Exp Immunol 1993; 92: 14-8.
13. Sullivan KE, Wooten C, Schmeckpeper BJ, Goldman D, Petri MA. A promoter polymorphism of tumor necrosis factor α associated with systemic lupus erythematosus in African Americans. Arthritis Rheum 1997; 40: 2207-11.
14. Chen CJ, Yen JH, Tsai WC, et al. The TNF2 allele does not contribute towards susceptibility to systemic lupus erythematosus. Immunol Lett 1997; 55: 1-3.
15. Rudwaleit M, Tikly M, Khamashta M, Gibson K, Klinke J, Hughes G, Wordsworth P. Interethnic differences in the association of tumor necrosis factor promoter polymorphisms with systemic lupus erythematosus. J Rheumatol 1997; 23: 1725-8.
16. Fong KY, Howe HS, Tin SK, Boey ML, Feng PH. Polymorphism of the regulatory region of tumour necrosis factor alpha gene in patients with systemic lupus erythematosus. Ann Acad Med Sing 1996; 25: 90-3.
17. May LA, Huang Q, Morris D, Danis V, Manolios N. Relationship of tumour necrosis factor alpha gene polymorphisms and neuropsychiatric lupus. Lupus 2002; 11: 114-8.