Interethnic differences in the association of tumor necrosis factor promoter polymorphisms with systemic lupud erythematosus

Journal of Rheumatology

Volumn 23, Issue 10, 1996, Pages 1725-1728

  Rudwaleit, Martin ^a   Tikly, Mohammed ^b   Khamashta, Munther ^c   Gibson, Kathryn ^a   Klinke, Jennifer ^a   Hughes, Graham ^c   Wordsworth, Paul ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^c ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

genetics; major histocompatibility complex; polymorphism

Indexed keywords

TUMOR NECROSIS FACTOR;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; ETHNIC DIFFERENCE; FEMALE; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; PRIORITY JOURNAL; SOUTH AFRICA; SYSTEMIC LUPUS ERYTHEMATOSUS; UNITED KINGDOM;

AFRICAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENE FREQUENCY; HLA-DR ANTIGENS; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); RISK FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0029847906     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Hartung K, Baur MP, Coldeway R, et al.: Major histocompatibility complex haplotypes and complement C4 alleles in systemic lupus erythematosus. J Clin Invest 1992;90:1346-51.
2. Batchelor JR: Systemic lupus erythematosus and genes within the HLA region. Br J Rheumatol 1993;32:13-5.
3. Vassalli P: The pathophysiology of tumor necrosis factors. Ann Rev Immunol 1992;10:411-52.
4. Santamaria P, Gehrz RC, Bryan MK, Barbosa JJ: Involvement of class II MHC haplotypes in the LPS-induction of IL-1/TNF secretions by human monocytes. J Immunol 1989;143:913-22.
5. Jacob CO, Fronek Z, Lewis GD, Koo M, Hansen J, McDevitt HO: Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor α: Relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci USA 1990;87:1233-7.
6. Pociot F, Briant L, Jongeneel CV, et al.: Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-α and TNF-β by human mononuclear cells: A possible link to insulin-dependent diabetes mellitus. Eur J Immunol 1993;23:224-31.
7. D'Alfonso S, Richiardi PM: A polymorphic variation in a putative regulation box of the TNFA promoter region. Immunogenetics 1994,39:150-4.
8. Wilson AC, di Giovine FS, Blakemore AIF, Duff GW: Single base polymorphism in the human tumor necrosis factor alpha (TNFα) gene detectable by Ncol restriction of PCR product. Hum Mol Genet 1992;1:353-8.
9. Wilson AG, Symons JA, McDonald TL, di Giovine FS, Duff GW: Effects of a tumor necrosis factor (TNFα) promoter base transition on transcriptional activity (abstr). Br J Rheumatol 1994;(suppl 1)33:89.
10. McGuire W, Hill AVS, Allsopp CEM, Greenwood BM, Kwiatkowski D: Variation in the TNF-α promoter region associated with susceptibility to cerebral malaria. Nature 1994;311:508-11.
11. Kwiatkowski D, Hill AVS, Sambou I, et al.: TNF concentrations in fatal cerebral, non-fatal cerebral and uncomplicated Plasmodium falciparum malaria. Lancet 1990;336:1201-4.
12. Wilson AG, Gordon C, di Giovine FS, et al.: A genetic association between systemic lupus erythematosus and tumor necrosis factor alpha. Eur J Immunol 1994;24:191-5.
13. Wilson AG, de Vries N, Pociot G, diGiovine FS, van der Putte LBA, Duff GW: An allelic polymorphism within the human tumor necrosis factor a promoter region is strongly associated with HLA A1, B8 and DR3 alleles. J Exp Med 1993;177:557-60.
14. Rudwaleit M, Tikly M, Gibson K, Pile K, Wordsworth P: HLA class II antigens associated with systemic lupus erythematosus in black South Africans. Ann Rheum Dis 1995;54:678-80.
15. Green PM, Bentley DR, Mibashan RS, Nilsson IM, Gianelli F: Molecular pathology of haemophilia B. EMBO J 1989;8:1067-72.
16. Kirkwood BR: Essentials of medical statistics. Oxford: Blackwell Scientific, 1988:173-83.
17. Adebajo A, Davis P: Rheumatic diseases in African Blacks. Semin Arthritis Rheum 1994;24:139-53.
18. Greenwood BM: Autoimmune disease and parasitic infections in Nigerians. Lancet 1968;2:380-2.
19. Jacob CO: Tumor necrosis factor α in autoimmunity: Pretty girl or old witch? Immunol Today 1992;4:122-5.
20. Butcher GA, Clark IA: SLE and malaria: Another look at an old idea. Parasitol Today 1990;6:259-61.
21. Hammond MG, Marcelli A, Poirier JC: Complement polymorphisms in African Blacks. In: Tsuji K, Aizawa M, Sasazuki T, eds. HLA 1991: Proceedings of the XI International Histocompatibility Workshop Yokohama, Japan, 1991. Oxford: Oxford University Press:968-70.