Rheological analysis of the structural properties effecting the percutaneous absorption and stability in pharmaceutical organogels

Rheologica Acta

Volumn 43, Issue 5, 2004, Pages 457-463

  Pénzes, Tímea ^a   Csóka, Ildikó ^a   Eros, István ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Emulsifier; Gel structure; In vitro percutaneous absorption; Organogel; Pharmaceutics

Indexed keywords

PHARMACEUTICAL INDUSTRY; RHEOLOGY; STRUCTURAL ANALYSIS;

EID: 8644234167     PISSN: 00354511     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00397-004-0396-1     Document Type: Article

References (15)

1. Abdou HM (2000) Effect of viscosity of the dissolution medium. In: Abdou HM (ed) Dissolution, bioavailability and bioequivalence. Mack, Easton, Pennsylvania, pp 161-170
2. Barry WB (1983a) Properties that influence percutaneous absorption. In: Barry WB (ed) Dermatological formulations: Percutan absorption. Marcel Dekker, New York, pp 154-158
3. Barry WB (1983b) Rheology of dermatological vehicles. In: Barry WB (ed) Dermatological formulations: Percutaneous absorption. Marcel Dekker, New York, pp 396-400
4. Davis SS (1971) Viscoelastic properties of pharmaceutical semisolids III. Nondestructive oscillatory testing. J Pharm Sci 60:1351-1356
5. Eros I, Hunyadvaári É (1972) Influence of w/o emulsifiers on the structure rheology of ointments. Sci Pharm 24-35 (in German)
6. Korhonen M, Niskanen H, Kiesvaara J, Yliruusi J (2000) Determination of optimal combination of surfactants in creams using rheology measurements. Int J Pharm 197:143-151
7. Korhonen M, Lehtonen J, Hellen L, Hirvonen J, Yliruusi J (2002) Rheological properties of three component creams containing sorbitan monoesters as surfactants. Int J Pharm 247:103-114
8. Murdan S, Gregoriadis G, Florence AT (1998) Novel sorbitan monostearate organogels. J Pharm Sci 88:608-614
9. Neubert R, Wohlrab W (1990) In vitro methods for the biopharmaceutical evaluation of topical formulation. Acta Pharm Technol 36:197-206
10. RheoWin Pro Data Manager (1997) ThermoHaake, Karlsruhe, Germany
11. Schramm G (1994) Some theoretical aspects of dynamic testing. In: Schramm G (ed) A practical approach to rheology and rheometry. Gebrueder HAAKE GmbH, Karlsruhe
12. Schurtenberger P, Scartazzini R, Luisi PL (1989) Viscoelastic properties of polymerlike reverse micelles. Rheol Acta 28:372-381
13. Shas VP, Elkins J, Hanus J, Noorizadeh C, Skelly JP (1991) In vitro release of hydrocortisone from topical preparations and automated procedure. Pharm Res 8:55-59
14. Shchipunov YA, Hoffmann H (2000) Thinning and thickening effects induced by shearing in lecithin solutions of polymer-like micelles. Rheol Acta 39:542-553
15. Welin-Berger K, Neelissen J, Bergenståhl B (2001) In vitro permeation profile of a local anaesthetic from topical formulations with different rheological behaviour - verified by in vivo efficacy data. Eur J Pharm Sci 14:229-236