Quantitative structure-activity relationships of Streptococcus pneumoniae MurD transition state analogue inhibitors

QSAR and Combinatorial Science

Volumn 23, Issue 6, 2004, Pages 399-405

  Kotnik, Miha ^a   Oblak, Marko ^b   Humljan, Jan ^a   Gobec, Stanislav ^c   Urleb, Uros ^a,c   Solmajer, Tom ^a,b,d  

^a Lek dd   (Slovenia)

^b NATIONAL INSTITUTE OF CHEMISTRY   (Slovenia)

^c UNIVERSITY OF LJUBLJANA   (Slovenia)

^d National Institute of Chemistry   (Slovenia)

Author keywords

Bacterial cell wall; MurD; QSAR; Transition state inhibitors

Indexed keywords

CELL MEMBRANES; COMPUTATIONAL CHEMISTRY; HYDROGEN BONDS;

BACTERIAL CELL WALL; BACTERIAL CELLS; CELL WALLS; MOLECULAR DESCRIPTORS; MURD; QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP STUDIES; STREPTOCOCCUS PNEUMONIAE; TRANSITION-STATE ANALOGUES; TRANSITION-STATE INHIBITORS;

MULTIPLE LINEAR REGRESSION;

BACTERIAL PROTEIN; CARBAPENEM DERIVATIVE; CEPHALOSPORIN DERIVATIVE; FOSFOMYCIN; LIGAND; MONOBACTAM DERIVATIVE; PENICILLIN DERIVATIVE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLMURAMOYLALANINE:GLUTAMATE LIGASE; VANCOMYCIN;

ARTICLE; COMPUTER PROGRAM; DRUG CONFORMATION; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; HYDROGEN BOND; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN INTERACTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STREPTOCOCCUS PNEUMONIAE;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE;

EID: 8544228354     PISSN: 1611020X     EISSN: None     Source Type: Journal    
DOI: 10.1002/qsar.200430875     Document Type: Article

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