Injectable polyethylene glycol-fibrinogen hydrogel adjuvant improves survival and differentiation of transplanted mesoangioblasts in acute and chronic skeletal-muscle degeneration

Skeletal Muscle

Volumn 2, Issue , 2012, Pages

  Fuoco, Claudia ^a   Salvatori, Maria Lavinia ^a   Biondo, Antonella ^b   Shapira Schweitzer, Keren ^c   Santoleri, Sabrina ^b   Antonini, Stefania ^d   Bernardini, Sergio ^a   Tedesco, Francesco Saverio ^b,d   Cannata, Stefano ^a   Seliktar, Dror ^c   Cossu, Giulio ^b,d   Gargioli, Cesare ^a,e  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e IRCCS MULTIMEDICA   (Italy)

Author keywords

Cell therapy; Hydrogel; Mesoangioblasts; Muscle regeneration; Muscular dystrophy; Stem cells; Tissue engineering

Indexed keywords

EID: 85188070766     PISSN: None     EISSN: 20445040     Source Type: Journal    
DOI: 10.1186/2044-5040-2-24     Document Type: Article

References (30)

1. Carlson BM: The regeneration of skeletal muscle. Am J Anat 1973, 137(2):119–149.
2. Beauchamp JR, Morgan JE, Pagel CN, Partridge TA: Dynamics of myoblast transplantation reveal a discrete minority of precursors with stem cell-like properties as the myogenic source. J Cell Biol 1999, 144(6):1113–1122.
3. Wernig A, Zweyr M, Irintchev A: Function of skeletal muscle tissue after myoblast transplantation into irradiated mouse muscles. J Phisiol 2000, 15:333–345.
4. Guérette B, Wood K, Roy R, Tremblay JP: Efficient myoblast transplantation in mice iccmmunosuppressed with monoclonal antibodies and CTLA4 Ig. Transplant Proc 1997, 29(4):1932–1934.
5. Mould V, Aamiri A, Périé S, Mamchaoui K, Barani A, Bigot A, et al: Myoblast transfer therapy: is there any light at the end of the tunnel? Acta Myol 2005, 24(2):128–133.
6. Gilbert PM, Havenstrite KL, Magnusson KE, Sacco A, Leonardi NA, Kraft P, Nguyen NK, Thrun S, Lutolf MP, Blau HM: Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. Science 2010, 329(5995):1078–1081.
7. Cossu G, Sampaolesi M: New therapies for muscular dystrophy: cautious optimism. Trends Mol Med 2004, 10(10):516–520.
8. Sampaolesi M, Torrente Y, Innocenzi A, Tonlorenzi R, D’Antona G, Pellegrino MA, et al: Cell therapy of alpha-sarcoglycan null dystrophic mice through intra-arterial delivery of mesoangioblasts. Science 2003, 301(5632):487–492.
9. Guttinger M, Tafi E, Battaglia M, Coletta M, Cossu G: Allogeneic mesoangioblasts give rise to alpha-sarcoglycan expressing fibers when transplanted into dystrophic mice. Exp Cell Res 2006, 312:3872–3879.
10. Sampaolesi M, Blot S, D’Antona G, Granger N, Tonlorenzi R, Innocenzi A, et al: Mesoangioblast stem cells ameliorate muscle function in dystrophic dogs. Nature 2006, 444(7119):574–579.
11. Rossi CA, Pozzobon M, De Coppi P: Advances in musculoskeletal tissue engineering: moving towards therapy. Organogenesis 2010, 6(3):167–172.
12. Liao H, Zhou GQ: Development and progress of engineering of skeletal muscle tissue. Tissue Eng 2009, 15(3):319–331.
13. Seliktar D: Designing cell-compatible hydrogels for biomedical applications. Science 2012, 336(6085):1124–1128.
14. Habib M, Shapira-Schweitzer K, Caspi O, Gepstein A, Arbel G, Aronson D, Seliktar D, Gepstein L: A combined cell therapy and in-situ tissue-engineering approach for myocardial repair. Biomaterials 2011, 32(30):7514–7523.
15. Matsumura G, Miyagawa-Tomita S, Shin’oka T, Ikada Y, Kurosawa H: First evidence that bone marrow cells contribute to the construction of tissue-engineered vascular autografts in vivo. Circulation 2003, 108:1729–1734.
16. Zammaretti P, Jaconi M: Cardiac tissue engineering: regeneration of the wounded heart. Curr Opin Biotechnol 2004, 15(5):430–434.
17. Rossi CA, Flaibani M, Blaauw B, Pozzobon M, Figallo E, Reggiani C, et al: In vivo tissue engineering of functional skeletal muscle by freshly isolated satellite cells embedded in a photopolymerizable hydrogel. FASEB J 2011, 25(7):2296–2304.
18. Peyton SR, Kim PD, Ghajar CM, Seliktar D, Putnam AJ: The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system. Biomaterials 2008, 29(17):2597–2607.
19. Almany L, Seliktar D: Biosynthetic hydrogel scaffolds made from fibrinogen and polyethylene glycol for 3D cell cultures. Biomaterials 2005, 26(15):2467–2477.
20. Minasi MG, Riminucci M, De Angelis L, Borello U, Berarducci B, Innocenzi A, et al: The meso-angioblast: a multipotent, self-renewing cell that originates from the dorsal aorta and differentiates into most mesodermal tissues. Development 2002, 129(11):2773–2783.
21. Tedesco FS, Gerli MF, Perani L, Benedetti S, Ungaro F, Cassano M, et al: Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy. Sci Transl Med 2012, 4(140):140ra89.
22. Gargioli C, Coletta M, De Grandis F, Cannata SM, Cossu G: PlGF-MMP-9-expressing cells restore microcirculation and efficacy of cell therapy in aged dystrophic muscle. Nat Med 2008, 14(9):973–978.
23. Schense JC, Hubbell JA: Cross-linking exogenous bifunctional peptides into fibrin gels with factor XIIIa. Bioconjug Chem 1999, 10(1):75–81.
24. Freudenberg U, Hermann A, Welzel PB, Stirl K, Schwarz SC, Grimmer M, et al: A star-PEG-heparin hydrogel platform to aid cell replacement therapies for neurodegenerative diseases. Biomaterials 2009, 30(28):5049–5060.
25. Ehrbar M, Rizzi SC, Schoenmakers RG, Miguel BS, Hubbell JA, Weber FE, Lutolf MP: Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions. Biomacromolecules 2007, 8(10):3000–3007.
26. Dellavalle A, Sampaolesi M, Tonlorenzi R, Tagliafico E, Sacchetti B, Perani L, et al: Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells. Nat Cell Biol 2007, 9(3):255–267.
27. Díaz-Manera J, Touvier T, Dellavalle A, Tonlorenzi R, Tedesco FS, Messina G, et al: Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy. Cell Death Dis 2010, 1(8):e61.
28. Shapira-Schweitzer K, Seliktar D: Matrix stiffness affects spontaneous contraction of cardiomyocytes cultured within a PEGylated fibrinogen biomaterial. Acta Biomater 2007, 3(1):33–41.
29. Cao X, Shores EW, Hu-Li J, Anver MR, Kelsall BL, Russell SM, et al: Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. Immunity 1995, 2:223–238.
30. Rosenblatt JD, Lunt AI, Parry AJ, Partridge TA: Culturing satellite cells from living single muscle fiber explants. In Vitro Cell Dev Biol Anim 1995, 31:773–779.