-
1
-
-
38649125210
-
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
-
JB Harley, ME Alarcon-Riquelme, LA Criswell, et al. (2008) Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 40(2), 204-210
-
(2008)
Nat Genet
, vol.40
, Issue.2
, pp. 204-210
-
-
Harley, J.B.1
Alarcon-Riquelme, M.E.2
Criswell, L.A.3
-
2
-
-
40049108936
-
Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX
-
G Hom, RR Graham, B Modrek, et al. (2008) Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. N Engl J Med 358(9), 900-909
-
(2008)
N Engl J Med
, vol.358
, Issue.9
, pp. 900-909
-
-
Hom, G.1
Graham, R.R.2
Modrek, B.3
-
3
-
-
78649830454
-
Genetic susceptibility to systemic lupus erythematosus in the genomic era
-
Y Deng and BP Tsao (2010) Genetic susceptibility to systemic lupus erythematosus in the genomic era. Nat Rev Rheumatol 6(12), 683-692
-
(2010)
Nat Rev Rheumatol
, vol.6
, Issue.12
, pp. 683-692
-
-
Deng, Y.1
Tsao, B.P.2
-
4
-
-
0032902704
-
The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases
-
P Price, C Witt, R Allcock, et al. (1999) The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases. Immunol Rev 167 257-274
-
(1999)
Immunol Rev
, vol.167
, pp. 257-274
-
-
Price, P.1
Witt, C.2
Allcock, R.3
-
5
-
-
77956919523
-
Clearance of dying cells and systemic lupus erythematosus: the role of C1q and the complement system
-
D Mevorach (2010) Clearance of dying cells and systemic lupus erythematosus: the role of C1q and the complement system. Apoptosis 15(9), 1114-1123
-
(2010)
Apoptosis
, vol.15
, Issue.9
, pp. 1114-1123
-
-
Mevorach, D.1
-
6
-
-
78049496573
-
C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes
-
DM Santer, BE Hall, TC George, et al. (2010) C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes. J Immunol 185(8), 4738-4749
-
(2010)
J Immunol
, vol.185
, Issue.8
, pp. 4738-4749
-
-
Santer, D.M.1
Hall, B.E.2
George, T.C.3
-
7
-
-
34147185679
-
Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome
-
G Rice, WG Newman, J Dean, et al. (2007) Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome. Am J Hum Genet 80(4), 811-815
-
(2007)
Am J Hum Genet
, vol.80
, Issue.4
, pp. 811-815
-
-
Rice, G.1
Newman, W.G.2
Dean, J.3
-
8
-
-
34548327158
-
Mutations in the gene encoding the 3’-5’ DNA exonuclease TREX1 are associated with systemic lupus erythematosus
-
MA Lee-Kirsch, M Gong, D Chowdhury, et al. (2007) Mutations in the gene encoding the 3’-5’ DNA exonuclease TREX1 are associated with systemic lupus erythematosus. Nat Genet 39(9), 1065-1067
-
(2007)
Nat Genet
, vol.39
, Issue.9
, pp. 1065-1067
-
-
Lee-Kirsch, M.A.1
Gong, M.2
Chowdhury, D.3
-
9
-
-
67649861901
-
Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response
-
GI Rice, J Bond, A Asipu, et al. (2009) Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response. Nat Genet 41(7), 829-832
-
(2009)
Nat Genet
, vol.41
, Issue.7
, pp. 829-832
-
-
Rice, G.I.1
Bond, J.2
Asipu, A.3
-
10
-
-
49549100511
-
Trex1 prevents cell-intrinsic initiation of autoimmunity
-
DB Stetson, JS Ko, T Heidmann and R Medzhitov (2008) Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell 134(4), 587-598
-
(2008)
Cell
, vol.134
, Issue.4
, pp. 587-598
-
-
Stetson, D.B.1
Ko, J.S.2
Heidmann, T.3
Medzhitov, R.4
-
11
-
-
79958015275
-
Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
-
B Namjou, PH Kothari, JA Kelly, et al. (2011) Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort. Genes Immun 12(4), 270-279
-
(2011)
Genes Immun
, vol.12
, Issue.4
, pp. 270-279
-
-
Namjou, B.1
Kothari, P.H.2
Kelly, J.A.3
-
12
-
-
49449104525
-
Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients
-
TB Niewold, JA Kelly, MH Flesch, et al. (2008) Association of the IRF5 risk haplotype with high serum interferon-alpha activity in systemic lupus erythematosus patients. Arthritis Rheum 58(8), 2481-2487
-
(2008)
Arthritis Rheum
, vol.58
, Issue.8
, pp. 2481-2487
-
-
Niewold, T.B.1
Kelly, J.A.2
Flesch, M.H.3
-
13
-
-
77954877255
-
Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus
-
SN Kariuki, BS Franek, AA Kumar, et al. (2010) Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus. Arthritis Res Ther 12(4), R151
-
(2010)
Arthritis Res Ther
, vol.12
, Issue.4
, pp. R151
-
-
Kariuki, S.N.1
Franek, B.S.2
Kumar, A.A.3
-
14
-
-
79959828831
-
Genetic analyses of interferon pathway-related genes reveals multiple new loci associated with systemic lupus erythematosus (SLE)
-
PS Ramos, AH Williams, JT Ziegler, et al. (2011) Genetic analyses of interferon pathway-related genes reveals multiple new loci associated with systemic lupus erythematosus (SLE). Arthritis Rheum 63 2049-2057
-
(2011)
Arthritis Rheum
, vol.63
, pp. 2049-2057
-
-
Ramos, P.S.1
Williams, A.H.2
Ziegler, J.T.3
-
15
-
-
5444223519
-
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
-
DL Boone, EE Turer, EG Lee, et al. (2004) The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat Immunol 5(10), 1052-1060
-
(2004)
Nat Immunol
, vol.5
, Issue.10
, pp. 1052-1060
-
-
Boone, D.L.1
Turer, E.E.2
Lee, E.G.3
-
16
-
-
34547182875
-
Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE
-
RR Graham, W Ortmann, P Rodine, et al. (2007) Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE. Eur J Hum Genet 15(8), 823-830
-
(2007)
Eur J Hum Genet
, vol.15
, Issue.8
, pp. 823-830
-
-
Graham, R.R.1
Ortmann, W.2
Rodine, P.3
-
17
-
-
65249086734
-
Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans
-
K Liu, QZ Li, AM Delgado-Vega, et al. (2009) Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. J Clin Invest 119(4), 911-923
-
(2009)
J Clin Invest
, vol.119
, Issue.4
, pp. 911-923
-
-
Liu, K.1
Li, Q.Z.2
Delgado-Vega, A.M.3
-
18
-
-
75749110600
-
Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients
-
R Salloum, BS Franek, SN Kariuki, et al. (2010) Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon-alpha activity in lupus patients. Arthritis Rheum 62(2), 553-561
-
(2010)
Arthritis Rheum
, vol.62
, Issue.2
, pp. 553-561
-
-
Salloum, R.1
Franek, B.S.2
Kariuki, S.N.3
-
19
-
-
79953743757
-
Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production
-
SA Chung, KE Taylor, RR Graham, et al. (2011) Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. PLoS Genet 7(3), e1001323
-
(2011)
PLoS Genet
, vol.7
, Issue.3
, pp. e1001323
-
-
Chung, S.A.1
Taylor, K.E.2
Graham, R.R.3
-
20
-
-
79952261842
-
Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes
-
KE Taylor, SA Chung, RR Graham, et al. (2011) Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes. PLoS Genet 7(2), e1001311
-
(2011)
PLoS Genet
, vol.7
, Issue.2
, pp. e1001311
-
-
Taylor, K.E.1
Chung, S.A.2
Graham, R.R.3
-
21
-
-
46849085591
-
Hormonal regulation of B-cell function and systemic lupus erythematosus
-
JF Cohen-Solal, V Jeganathan, L Hill, et al. (2008) Hormonal regulation of B-cell function and systemic lupus erythematosus. Lupus 17(6), 528-532
-
(2008)
Lupus
, vol.17
, Issue.6
, pp. 528-532
-
-
Cohen-Solal, J.F.1
Jeganathan, V.2
Hill, L.3
-
22
-
-
49449099801
-
Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome
-
RH Scofield, GR Bruner, B Namjou, et al. (2008) Klinefelter's syndrome (47,XXY) in male systemic lupus erythematosus patients: support for the notion of a gene-dose effect from the X chromosome. Arthritis Rheum 58(8), 2511-2517
-
(2008)
Arthritis Rheum
, vol.58
, Issue.8
, pp. 2511-2517
-
-
Scofield, R.H.1
Bruner, G.R.2
Namjou, B.3
-
23
-
-
36048962438
-
Control of Toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
-
JA Deane, P Pisitkun, RS Barrett, et al. (2007) Control of Toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity 27(5), 801-810
-
(2007)
Immunity
, vol.27
, Issue.5
, pp. 801-810
-
-
Deane, J.A.1
Pisitkun, P.2
Barrett, R.S.3
-
24
-
-
75649151209
-
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
-
BM Javierre, AF Fernandez, J Richter, et al. (2010) Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus. Genome Res 20(2), 170-179
-
(2010)
Genome Res
, vol.20
, Issue.2
, pp. 170-179
-
-
Javierre, B.M.1
Fernandez, A.F.2
Richter, J.3
-
25
-
-
34247193197
-
Reproductive and menopausal factors and risk of systemic lupus erythematosus in women
-
KH Costenbader, D Feskanich, MJ Stampfer and EW Karlson (2007) Reproductive and menopausal factors and risk of systemic lupus erythematosus in women. Arthritis Rheum 56(4), 1251-1262
-
(2007)
Arthritis Rheum
, vol.56
, Issue.4
, pp. 1251-1262
-
-
Costenbader, K.H.1
Feskanich, D.2
Stampfer, M.J.3
Karlson, E.W.4
-
26
-
-
80051807498
-
piRNAs, transposon silencing, and germline genome integrity
-
J Castañeda, P Genzor and A Bortvin (2011) piRNAs, transposon silencing, and germline genome integrity. Mutat Res 714 95-104
-
(2011)
Mutat Res
, vol.714
, pp. 95-104
-
-
Castañeda, J.1
Genzor, P.2
Bortvin, A.3
-
27
-
-
33747811513
-
Systemic lupus erythematosus in a multiethnic cohort: LUMINA XXXV. Predictive factors of high disease activity over time
-
GS Alarcon, J Calvo-Alen, G McGwin Jr, et al. (2006) Systemic lupus erythematosus in a multiethnic cohort: LUMINA XXXV. Predictive factors of high disease activity over time. Ann Rheum Dis 65(9), 1168-1174
-
(2006)
Ann Rheum Dis
, vol.65
, Issue.9
, pp. 1168-1174
-
-
Alarcon, G.S.1
Calvo-Alen, J.2
McGwin, G.3
-
28
-
-
10344228936
-
Patients with systemic lupus erythematosus have abnormally elevated Epstein-Barr virus load in blood
-
UY Moon, SJ Park, ST Oh, et al. (2004) Patients with systemic lupus erythematosus have abnormally elevated Epstein-Barr virus load in blood. Arthritis Res Ther 6(4), R295-302
-
(2004)
Arthritis Res Ther
, vol.6
, Issue.4
, pp. R295-302
-
-
Moon, U.Y.1
Park, S.J.2
Oh, S.T.3
-
29
-
-
60649120289
-
Aberrant Epstein-Barr viral infection in systemic lupus erythematosus
-
BD Poole, AK Templeton, JM Guthridge, et al. (2009) Aberrant Epstein-Barr viral infection in systemic lupus erythematosus. Autoimmun Rev 8(4), 337-342
-
(2009)
Autoimmun Rev
, vol.8
, Issue.4
, pp. 337-342
-
-
Poole, B.D.1
Templeton, A.K.2
Guthridge, J.M.3
-
30
-
-
77958146282
-
Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice
-
AL Peters, LL Stunz, DK Meyerholz, et al. (2010) Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice. J Immunol 185(7), 4053-4062
-
(2010)
J Immunol
, vol.185
, Issue.7
, pp. 4053-4062
-
-
Peters, A.L.1
Stunz, L.L.2
Meyerholz, D.K.3
-
31
-
-
79251567049
-
Antibodies elicited in response to EBNA-1 may cross-react with dsDNA
-
P Yadav, H Tran, R Ebegbe, et al. (2011) Antibodies elicited in response to EBNA-1 may cross-react with dsDNA. PLoS One 6(1), e14488
-
(2011)
PLoS One
, vol.6
, Issue.1
, pp. e14488
-
-
Yadav, P.1
Tran, H.2
Ebegbe, R.3
-
32
-
-
1642495711
-
Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus
-
I Kang, T Quan, H Nolasco, et al. (2004) Defective control of latent Epstein-Barr virus infection in systemic lupus erythematosus. J Immunol 172(2), 1287-1294
-
(2004)
J Immunol
, vol.172
, Issue.2
, pp. 1287-1294
-
-
Kang, I.1
Quan, T.2
Nolasco, H.3
-
33
-
-
1542283749
-
Cigarette smoking and the risk of systemic lupus erythematosus: a meta-analysis
-
KH Costenbader, DJ Kim, J Peerzada, et al. (2004) Cigarette smoking and the risk of systemic lupus erythematosus: a meta-analysis. Arthritis Rheum 50(3), 849-857
-
(2004)
Arthritis Rheum
, vol.50
, Issue.3
, pp. 849-857
-
-
Costenbader, K.H.1
Kim, D.J.2
Peerzada, J.3
-
34
-
-
38449104652
-
Impaired T cell protein kinase C delta activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus
-
G Gorelik, JY Fang, A Wu, et al. (2007) Impaired T cell protein kinase C delta activation decreases ERK pathway signaling in idiopathic and hydralazine-induced lupus. J Immunol 179(8), 5553-5563
-
(2007)
J Immunol
, vol.179
, Issue.8
, pp. 5553-5563
-
-
Gorelik, G.1
Fang, J.Y.2
Wu, A.3
-
35
-
-
0037451167
-
Interferon and granulopoiesis signatures in systemic lupus erythematosus blood
-
L Bennett, AK Palucka, E Arce, et al. (2003) Interferon and granulopoiesis signatures in systemic lupus erythematosus blood. J Exp Med 197(6), 711-723
-
(2003)
J Exp Med
, vol.197
, Issue.6
, pp. 711-723
-
-
Bennett, L.1
Palucka, A.K.2
Arce, E.3
-
36
-
-
0344492212
-
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
-
EC Baechler, FM Batliwalla, G Karypis, et al. (2003) Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci U S A 100(5), 2610-2615
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.5
, pp. 2610-2615
-
-
Baechler, E.C.1
Batliwalla, F.M.2
Karypis, G.3
-
37
-
-
0344665750
-
Microarray analysis of interferon-regulated genes in SLE
-
MK Crow, KA Kirou and J Wohlgemuth (2003) Microarray analysis of interferon-regulated genes in SLE. Autoimmunity 36(8), 481-490
-
(2003)
Autoimmunity
, vol.36
, Issue.8
, pp. 481-490
-
-
Crow, M.K.1
Kirou, K.A.2
Wohlgemuth, J.3
-
38
-
-
2642528779
-
Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG
-
T Lovgren, ML Eloranta, U Bave, et al. (2004) Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum 50(6), 1861-1872
-
(2004)
Arthritis Rheum
, vol.50
, Issue.6
, pp. 1861-1872
-
-
Lovgren, T.1
Eloranta, M.L.2
Bave, U.3
-
39
-
-
0041832267
-
Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG
-
U Bave, M Magnusson, ML Eloranta, et al. (2003) Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG. J Immunol 171(6), 3296-3302
-
(2003)
J Immunol
, vol.171
, Issue.6
, pp. 3296-3302
-
-
Bave, U.1
Magnusson, M.2
Eloranta, M.L.3
-
40
-
-
26844467349
-
Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
-
FJ Barrat, T Meeker, J Gregorio, et al. (2005) Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus. J Exp Med 202(8), 1131-1139
-
(2005)
J Exp Med
, vol.202
, Issue.8
, pp. 1131-1139
-
-
Barrat, F.J.1
Meeker, T.2
Gregorio, J.3
-
41
-
-
18644384042
-
Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease
-
KA Kirou, C Lee, S George, et al. (2005) Activation of the interferon-alpha pathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease. Arthritis Rheum 52(5), 1491-1503
-
(2005)
Arthritis Rheum
, vol.52
, Issue.5
, pp. 1491-1503
-
-
Kirou, K.A.1
Lee, C.2
George, S.3
-
42
-
-
33748472865
-
Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
-
SR Christensen, J Shupe, K Nickerson, et al. (2006) Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25(3), 417-428
-
(2006)
Immunity
, vol.25
, Issue.3
, pp. 417-428
-
-
Christensen, S.R.1
Shupe, J.2
Nickerson, K.3
-
43
-
-
77949903821
-
TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus
-
KM Nickerson, SR Christensen, J Shupe, et al. (2010) TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus. J Immunol 184(4), 1840-1848
-
(2010)
J Immunol
, vol.184
, Issue.4
, pp. 1840-1848
-
-
Nickerson, K.M.1
Christensen, S.R.2
Shupe, J.3
-
44
-
-
77956454663
-
Platelet CD154 potentiates interferon-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosus
-
P Duffau, J Seneschal, C Nicco, et al. (2010) Platelet CD154 potentiates interferon-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosus. Sci Transl Med 2(47), 47ra63
-
(2010)
Sci Transl Med
, vol.2
, Issue.47
, pp. 47ra63
-
-
Duffau, P.1
Seneschal, J.2
Nicco, C.3
-
45
-
-
77951935256
-
A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs
-
MF Denny, S Yalavarthi, W Zhao, et al. (2010) A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs. J Immunol 184(6), 3284-3297
-
(2010)
J Immunol
, vol.184
, Issue.6
, pp. 3284-3297
-
-
Denny, M.F.1
Yalavarthi, S.2
Zhao, W.3
-
46
-
-
79951777504
-
Nucleosome-induced neutrophil activation occurs independently of TLR9 and endosomal acidification: implications for systemic lupus erythematosus
-
D Lindau, V Ronnefarth, A Erbacher, et al. (2011) Nucleosome-induced neutrophil activation occurs independently of TLR9 and endosomal acidification: implications for systemic lupus erythematosus. Eur J Immunol 41(3), 669-681
-
(2011)
Eur J Immunol
, vol.41
, Issue.3
, pp. 669-681
-
-
Lindau, D.1
Ronnefarth, V.2
Erbacher, A.3
-
47
-
-
79952476762
-
Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus
-
GS Garcia-Romo, S Caielli, B Vega, et al. (2011) Netting neutrophils are major inducers of type I IFN production in pediatric systemic lupus erythematosus. Sci Transl Med 3(73), 73ra20
-
(2011)
Sci Transl Med
, vol.3
, Issue.73
, pp. 73ra20
-
-
Garcia-Romo, G.S.1
Caielli, S.2
Vega, B.3
-
48
-
-
79952468782
-
Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus
-
R Lande, D Ganguly, V Facchinetti, et al. (2011) Neutrophils activate plasmacytoid dendritic cells by releasing self-DNA-peptide complexes in systemic lupus erythematosus. Sci Transl Med 3(73), 73ra19
-
(2011)
Sci Transl Med
, vol.3
, Issue.73
, pp. 73ra19
-
-
Lande, R.1
Ganguly, D.2
Facchinetti, V.3
-
49
-
-
79960392810
-
Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus
-
E Villanueva, S Yalavarthi, CC Berthier, et al. (2011) Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J Immunol 187(1), 538-552
-
(2011)
J Immunol
, vol.187
, Issue.1
, pp. 538-552
-
-
Villanueva, E.1
Yalavarthi, S.2
Berthier, C.C.3
-
50
-
-
79954950134
-
Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus
-
AJ Ullal, CF Reich 3rd, M Clowse, et al. (2011) Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus. J Autoimmun 36(3-4), 173-180
-
(2011)
J Autoimmun
, vol.36
, Issue.3-4
, pp. 173-180
-
-
Ullal, A.J.1
Reich, C.F.2
Clowse, M.3
-
51
-
-
64649093433
-
Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells
-
B Gullstrand, U Martensson, G Sturfelt, et al. (2009) Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells. Clin Exp Immunol 156(2), 303-311
-
(2009)
Clin Exp Immunol
, vol.156
, Issue.2
, pp. 303-311
-
-
Gullstrand, B.1
Martensson, U.2
Sturfelt, G.3
-
52
-
-
0026528723
-
Dissociation of primary antigen-antibody bonds is essential for complement mediated solubilization of immune precipitates
-
A Johnston, GR Auda, MA Kerr, et al. (1992) Dissociation of primary antigen-antibody bonds is essential for complement mediated solubilization of immune precipitates. Mol Immunol 29(5), 659-665
-
(1992)
Mol Immunol
, vol.29
, Issue.5
, pp. 659-665
-
-
Johnston, A.1
Auda, G.R.2
Kerr, M.A.3
-
53
-
-
77953229472
-
T cells as therapeutic targets in SLE
-
JC Crispin, VC Kyttaris, C Terhorst and GC Tsokos (2010) T cells as therapeutic targets in SLE. Nat Rev Rheumatol 6(6), 317-325
-
(2010)
Nat Rev Rheumatol
, vol.6
, Issue.6
, pp. 317-325
-
-
Crispin, J.C.1
Kyttaris, V.C.2
Terhorst, C.3
Tsokos, G.C.4
-
54
-
-
33847342813
-
IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells
-
R Ettinger, GP Sims, R Robbins, et al. (2007) IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J Immunol 178(5), 2872-2882
-
(2007)
J Immunol
, vol.178
, Issue.5
, pp. 2872-2882
-
-
Ettinger, R.1
Sims, G.P.2
Robbins, R.3
-
55
-
-
0038342830
-
Reconstitution of deficient T cell receptor zeta chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus
-
MP Nambiar, CU Fisher, VG Warke, et al. (2003) Reconstitution of deficient T cell receptor zeta chain restores T cell signaling and augments T cell receptor/CD3-induced interleukin-2 production in patients with systemic lupus erythematosus. Arthritis Rheum 48(7), 1948-1955
-
(2003)
Arthritis Rheum
, vol.48
, Issue.7
, pp. 1948-1955
-
-
Nambiar, M.P.1
Fisher, C.U.2
Warke, V.G.3
-
56
-
-
33749345289
-
Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus
-
D Fernandez, E Bonilla, N Mirza, et al. (2006) Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus. Arthritis Rheum 54(9), 2983-2988
-
(2006)
Arthritis Rheum
, vol.54
, Issue.9
, pp. 2983-2988
-
-
Fernandez, D.1
Bonilla, E.2
Mirza, N.3
-
57
-
-
0142247168
-
DNA methylation and autoimmune disease
-
B Richardson (2003) DNA methylation and autoimmune disease. Clin Immunol 109(1), 72-79
-
(2003)
Clin Immunol
, vol.109
, Issue.1
, pp. 72-79
-
-
Richardson, B.1
-
58
-
-
74849138095
-
Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus
-
N Simpson, PA Gatenby, A Wilson, et al. (2010) Expansion of circulating T cells resembling follicular helper T cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus. Arthritis Rheum 62(1), 234-244
-
(2010)
Arthritis Rheum
, vol.62
, Issue.1
, pp. 234-244
-
-
Simpson, N.1
Gatenby, P.A.2
Wilson, A.3
-
59
-
-
79959328032
-
ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6
-
YS Choi, R Kageyama, D Eto, et al. (2011) ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6. Immunity 34(6), 932-946
-
(2011)
Immunity
, vol.34
, Issue.6
, pp. 932-946
-
-
Choi, Y.S.1
Kageyama, R.2
Eto, D.3
-
60
-
-
77952240517
-
+ T cell transcription signature predicts prognosis in autoimmune disease
-
EF McKinney, PA Lyons, EJ Carr, et al. (2010) A CD8+ T cell transcription signature predicts prognosis in autoimmune disease. Nat Med 16(5), 586-591
-
(2010)
Nat Med
, vol.16
, Issue.5
, pp. 586-591
-
-
McKinney, E.F.1
Lyons, P.A.2
Carr, E.J.3
-
61
-
-
84863517147
-
Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis
-
Q Xing, B Wang, H Su, et al. (2012) Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis. Rheumatol Int 32(4), 949-958
-
(2012)
Rheumatol Int
, vol.32
, Issue.4
, pp. 949-958
-
-
Xing, Q.1
Wang, B.2
Su, H.3
-
62
-
-
77954548831
-
The IL-2 defect in systemic lupus erythematosus disease has an expansive effect on host immunity
-
LA Lieberman and GC Tsokos (2010) The IL-2 defect in systemic lupus erythematosus disease has an expansive effect on host immunity. J Biomed Biotechnol 2010 740619
-
(2010)
J Biomed Biotechnol
, vol.2010
, pp. 740619
-
-
Lieberman, L.A.1
Tsokos, G.C.2
-
63
-
-
80051475298
-
Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus
-
LL Ritterhouse, SR Crowe, TB Niewold, et al. (2011) Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus. Ann Rheum Dis 70 1569-1574
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1569-1574
-
-
Ritterhouse, L.L.1
Crowe, S.R.2
Niewold, T.B.3
-
64
-
-
80052376347
-
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans
-
L Menard, D Saadoun, I Isnardi, et al. (2011) The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans. J Clin Invest 121 3635-3644
-
(2011)
J Clin Invest
, vol.121
, pp. 3635-3644
-
-
Menard, L.1
Saadoun, D.2
Isnardi, I.3
-
65
-
-
29144478403
-
Decreased LYN expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus
-
F Flores-Borja, PS Kabouridis, EC Jury, et al. (2005) Decreased LYN expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus. Arthritis Rheum 52(12), 3955-3965
-
(2005)
Arthritis Rheum
, vol.52
, Issue.12
, pp. 3955-3965
-
-
Flores-Borja, F.1
Kabouridis, P.S.2
Jury, E.C.3
-
66
-
-
67849097322
-
Genetic associations of LYN with systemic lupus erythematosus
-
R Lu, GS Vidal, JA Kelly, AM Delgado-Vega, et al. (2009) Genetic associations of LYN with systemic lupus erythematosus. Genes Immun 10(5), 397-403
-
(2009)
Genes Immun
, vol.10
, Issue.5
, pp. 397-403
-
-
Lu, R.1
Vidal, G.S.2
Kelly, J.A.3
Delgado-Vega, A.M.4
-
67
-
-
0242579484
-
A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling
-
X Li, J Wu, RH Carter, JC Edberg, et al. (2003) A novel polymorphism in the Fcgamma receptor IIB (CD32B) transmembrane region alters receptor signaling. Arthritis Rheum 48(11), 3242-3252
-
(2003)
Arthritis Rheum
, vol.48
, Issue.11
, pp. 3242-3252
-
-
Li, X.1
Wu, J.2
Carter, R.H.3
Edberg, J.C.4
-
68
-
-
26944456633
-
Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus
-
MC Blank, RN Stefanescu, E Masuda, et al. (2005) Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus. Hum Genet 117(2-3), 220-227
-
(2005)
Hum Genet
, vol.117
, Issue.2-3
, pp. 220-227
-
-
Blank, M.C.1
Stefanescu, R.N.2
Masuda, E.3
-
69
-
-
79955019213
-
Antibody-mediated coengagement of FcgammaRIIb and B cell receptor complex suppresses humoral immunity in systemic lupus erythematosus
-
HM Horton, SY Chu, EC Ortiz, et al. (2011) Antibody-mediated coengagement of FcgammaRIIb and B cell receptor complex suppresses humoral immunity in systemic lupus erythematosus. J Immunol 186(7), 4223-4233
-
(2011)
J Immunol
, vol.186
, Issue.7
, pp. 4223-4233
-
-
Horton, H.M.1
Chu, S.Y.2
Ortiz, E.C.3
-
70
-
-
79952452617
-
Long-lived autoreactive plasma cells drive persistent autoimmune inflammation
-
F Hiepe, T Dorner, AE Hauser, et al. (2011) Long-lived autoreactive plasma cells drive persistent autoimmune inflammation. Nat Rev Rheumatol 7(3), 170-178
-
(2011)
Nat Rev Rheumatol
, vol.7
, Issue.3
, pp. 170-178
-
-
Hiepe, F.1
Dorner, T.2
Hauser, A.E.3
-
71
-
-
73449114618
-
HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus
-
AM Jacobi, H Mei, BF Hoyer, et al. (2010) HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus. Ann Rheum Dis 69(1), 305-308
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.1
, pp. 305-308
-
-
Jacobi, A.M.1
Mei, H.2
Hoyer, B.F.3
-
72
-
-
33750316269
-
The binding of lupus-derived autoantibodies to the C-terminal peptide (83–119) of the major SmD1 autoantigen can be mediated by double-stranded DNA and nucleosomes
-
JW Dieker, CC Van Bavel, G Riemekasten, et al. (2006) The binding of lupus-derived autoantibodies to the C-terminal peptide (83–119) of the major SmD1 autoantigen can be mediated by double-stranded DNA and nucleosomes. Ann Rheum Dis 65(11), 1525-1528
-
(2006)
Ann Rheum Dis
, vol.65
, Issue.11
, pp. 1525-1528
-
-
Dieker, J.W.1
Van Bavel, C.C.2
Riemekasten, G.3
-
73
-
-
33846689677
-
The systemic and SmD183–119-autoantigen-specific cytokine memory of Th cells in SLE patients
-
S Langer, D Langnickel, P Enghard, et al. (2007) The systemic and SmD183–119-autoantigen-specific cytokine memory of Th cells in SLE patients. Rheumatology (Oxford) 46(2), 238-245
-
(2007)
Rheumatology (Oxford)
, vol.46
, Issue.2
, pp. 238-245
-
-
Langer, S.1
Langnickel, D.2
Enghard, P.3
-
74
-
-
0142009533
-
Development of autoantibodies before the clinical onset of systemic lupus erythematosus
-
MR Arbuckle, MT McClain, MV Rubertone, et al. (2003) Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 349(16), 1526-1533
-
(2003)
N Engl J Med
, vol.349
, Issue.16
, pp. 1526-1533
-
-
Arbuckle, M.R.1
McClain, M.T.2
Rubertone, M.V.3
-
75
-
-
76249117985
-
Differential responses to Smith D autoantigen by mice with HLA-DR and HLA-DQ transgenes: dominant responses by HLA-DR3 transgenic mice with diversification of autoantibodies to small nuclear ribonucleoprotein, double-stranded DNA, and nuclear antigens
-
C Jiang, US Deshmukh, F Gaskin, et al. (2010) Differential responses to Smith D autoantigen by mice with HLA-DR and HLA-DQ transgenes: dominant responses by HLA-DR3 transgenic mice with diversification of autoantibodies to small nuclear ribonucleoprotein, double-stranded DNA, and nuclear antigens. J Immunol 184(2), 1085-1091
-
(2010)
J Immunol
, vol.184
, Issue.2
, pp. 1085-1091
-
-
Jiang, C.1
Deshmukh, U.S.2
Gaskin, F.3
-
76
-
-
70349238894
-
Autoantibodies against complement C1q specifically target C1q bound on early apoptotic cells
-
C Bigler, M Schaller, I Perahud, et al. (2009) Autoantibodies against complement C1q specifically target C1q bound on early apoptotic cells. J Immunol 183(5), 3512-3521
-
(2009)
J Immunol
, vol.183
, Issue.5
, pp. 3512-3521
-
-
Bigler, C.1
Schaller, M.2
Perahud, I.3
-
77
-
-
70249140955
-
Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis
-
Y Chen, S Khanna, CS Goodyear, et al. (2009) Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. J Immunol 183(2), 1346-1359
-
(2009)
J Immunol
, vol.183
, Issue.2
, pp. 1346-1359
-
-
Chen, Y.1
Khanna, S.2
Goodyear, C.S.3
-
78
-
-
0035173156
-
A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus
-
LA DeGiorgio, KN Konstantinov, SC Lee, et al. (2001) A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus. Nat Med 7(11), 1189-1193
-
(2001)
Nat Med
, vol.7
, Issue.11
, pp. 1189-1193
-
-
DeGiorgio, L.A.1
Konstantinov, K.N.2
Lee, S.C.3
-
79
-
-
79960414998
-
β2-Glycoprotein I and protection from anti-SSA/Ro60-associated cardiac manifestations of neonatal lupus
-
JH Reed, RM Clancy, AW Purcell, et al. (2011) β2-Glycoprotein I and protection from anti-SSA/Ro60-associated cardiac manifestations of neonatal lupus. J Immunol 187(1), 520-526
-
(2011)
J Immunol
, vol.187
, Issue.1
, pp. 520-526
-
-
Reed, J.H.1
Clancy, R.M.2
Purcell, A.W.3
-
80
-
-
0346969977
-
Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome
-
G Girardi, J Berman, P Redecha, et al. (2003) Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome. J Clin Invest 112(11), 1644-1654
-
(2003)
J Clin Invest
, vol.112
, Issue.11
, pp. 1644-1654
-
-
Girardi, G.1
Berman, J.2
Redecha, P.3
-
81
-
-
79955018853
-
A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis
-
R Bethunaickan, CC Berthier, M Ramanujam, et al. (2011) A unique hybrid renal mononuclear phagocyte activation phenotype in murine systemic lupus erythematosus nephritis. J Immunol 186(8), 4994-5003
-
(2011)
J Immunol
, vol.186
, Issue.8
, pp. 4994-5003
-
-
Bethunaickan, R.1
Berthier, C.C.2
Ramanujam, M.3
-
82
-
-
77649267179
-
Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages
-
A Triantafyllopoulou, CW Franzke, SV Seshan, et al. (2010) Proliferative lesions and metalloproteinase activity in murine lupus nephritis mediated by type I interferons and macrophages. Proc Natl Acad Sci U S A 107(7), 3012-3017
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.7
, pp. 3012-3017
-
-
Triantafyllopoulou, A.1
Franzke, C.W.2
Seshan, S.V.3
-
83
-
-
0023888694
-
Increased levels of plasma anaphylatoxins in systemic lupus erythematosus predict flares of the disease and may elicit vascular injury in lupus cerebritis
-
P Hopkins, HM Belmont, J Buyon, et al. (1988) Increased levels of plasma anaphylatoxins in systemic lupus erythematosus predict flares of the disease and may elicit vascular injury in lupus cerebritis. Arthritis Rheum 31(5), 632-641
-
(1988)
Arthritis Rheum
, vol.31
, Issue.5
, pp. 632-641
-
-
Hopkins, P.1
Belmont, H.M.2
Buyon, J.3
-
84
-
-
71049165046
-
Premature vascular damage in systemic lupus erythematosus
-
MJ Kaplan (2009) Premature vascular damage in systemic lupus erythematosus. Autoimmunity 42(7), 580-586
-
(2009)
Autoimmunity
, vol.42
, Issue.7
, pp. 580-586
-
-
Kaplan, M.J.1
-
85
-
-
68049098209
-
Dysfunctional proinflammatory high-density lipoproteins confer increased risk of atherosclerosis in women with systemic lupus erythematosus
-
M McMahon, J Grossman, B Skaggs, et al. (2009) Dysfunctional proinflammatory high-density lipoproteins confer increased risk of atherosclerosis in women with systemic lupus erythematosus. Arthritis Rheum 60(8), 2428-2437
-
(2009)
Arthritis Rheum
, vol.60
, Issue.8
, pp. 2428-2437
-
-
McMahon, M.1
Grossman, J.2
Skaggs, B.3
-
86
-
-
79954579299
-
Degos disease: a C5b-9/interferon-alpha-mediated endotheliopathy syndrome
-
CM Magro, JC Poe, C Kim, et al. (2011) Degos disease: a C5b-9/interferon-alpha-mediated endotheliopathy syndrome. Am J Clin Pathol 135(4), 599-610
-
(2011)
Am J Clin Pathol
, vol.135
, Issue.4
, pp. 599-610
-
-
Magro, C.M.1
Poe, J.C.2
Kim, C.3
|