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Volumn , Issue , 2004, Pages 129-138

Parkin and Its Role in Parkinson’s Disease

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EID: 85160154574     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1201/9780203508596-23     Document Type: Chapter
Times cited : (3)

References (63)
  • 1
    • 0037208645 scopus 로고    scopus 로고
    • Overview of the genetics of parkinsonism
    • Gasser T., Overview of the genetics of parkinsonism, Adv. Neurol., 91:143–152, 2003.
    • (2003) Adv. Neurol , vol.91 , pp. 143-152
    • Gasser, T.1
  • 2
    • 0030744876 scopus 로고    scopus 로고
    • Mutation in the α-synuclein gene identified in families with Parkinson’s disease
    • Polymeropoulos, M. H., Lavedan, C., Leroy, E. et al., Mutation in the α-synuclein gene identified in families with Parkinson’s disease, Science, 276:2045–2047, 1997.
    • (1997) Science , vol.276 , pp. 2045-2047
    • Polymeropoulos, M.H.1    Lavedan, C.2    Leroy, E.3
  • 3
    • 0030015934 scopus 로고    scopus 로고
    • Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism
    • Ishikawa, A., Tsuji, S., Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism, Neurology, 47(1):160–166, 1996.
    • (1996) Neurology , vol.47 , Issue.1 , pp. 160-166
    • Ishikawa, A.1    Tsuji, S.2
  • 4
    • 0028151448 scopus 로고
    • Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene
    • Ichinose, H., Ohye, T., Takahashi, E. et al., Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene, Nat. Genet., 8(3):236–242, 1994.
    • (1994) Nat. Genet , vol.8 , Issue.3 , pp. 236-242
    • Ichinose, H.1    Ohye, T.2    Takahashi, E.3
  • 5
    • 16944362288 scopus 로고    scopus 로고
    • Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2–27
    • Matsumine, H., Saito, M., Shimoda-Matsubayashi, S. et al., Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25.2–27, Am. J. Hum. Genet., 60(3):588–596, 1997.
    • (1997) Am. J. Hum. Genet , vol.60 , Issue.3 , pp. 588-596
    • Matsumine, H.1    Saito, M.2    Shimoda-Matsubayashi, S.3
  • 6
    • 1642618076 scopus 로고    scopus 로고
    • Chromosome 6-linked autosomal recessive early-onset parkinsonism: Linkage in european and algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family
    • Tassin, J., Durr, A., de Broucker, T. et al., Chromosome 6-linked autosomal recessive early-onset parkinsonism: Linkage in european and algerian families, extension of the clinical spectrum, and evidence of a small homozygous deletion in one family, Am. J. Hum. Genet., 63(1):88–94, 1998.
    • (1998) Am. J. Hum. Genet , vol.63 , Issue.1 , pp. 88-94
    • Tassin, J.1    Durr, A.2    De Broucker, T.3
  • 7
    • 0032231463 scopus 로고    scopus 로고
    • Autosomal recessive juvenile parkinsonism maps to 6q25.2-q27 in four ethnic groups: Detailed genetic mapping of the linked region
    • Jones, A. C., Yamamura, Y., Almasy, L. et al., Autosomal recessive juvenile parkinsonism maps to 6q25.2-q27 in four ethnic groups: Detailed genetic mapping of the linked region, Am. J. Hum. Genet., 63(1):80–87, 1998.
    • (1998) Am. J. Hum. Genet , vol.63 , Issue.1 , pp. 80-87
    • Jones, A.C.1    Yamamura, Y.2    Almasy, L.3
  • 8
    • 0032499264 scopus 로고    scopus 로고
    • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
    • Kitada, T., Asakawa, S., Hattori, N. et al., Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism, Nature, 392:605–608, 1998.
    • (1998) Nature , vol.392 , pp. 605-608
    • Kitada, T.1    Asakawa, S.2    Hattori, N.3
  • 9
    • 18244412384 scopus 로고    scopus 로고
    • Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals
    • Hattori, N., Kitada, T., Matsumine, H. et al., Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals, Ann. Neurol., 44(6):935–941, 1998.
    • (1998) Ann. Neurol , vol.44 , Issue.6 , pp. 935-941
    • Hattori, N.1    Kitada, T.2    Matsumine, H.3
  • 10
    • 0032564235 scopus 로고    scopus 로고
    • Homozygous deletions in parkin gene in European and North African families with autosomal recessive juvenile parkinsonism. The European Consortium on Genetic Susceptibility in Parkinson’s Disease and the French Parkinson’s Disease Genetics Study Group
    • Lücking, C. B., Abbas, N., Dürr, A. et al., Homozygous deletions in parkin gene in European and North African families with autosomal recessive juvenile parkinsonism. The European Consortium on Genetic Susceptibility in Parkinson’s Disease and the French Parkinson’s Disease Genetics Study Group, Lancet, 352(9137):1355–1356, 1998.
    • (1998) Lancet , vol.352 , Issue.9137 , pp. 1355-1356
    • Lücking, C.B.1    Abbas, N.2    Dürr, A.3
  • 11
    • 0345490853 scopus 로고    scopus 로고
    • A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe
    • Abbas, N., Lücking, C. B., Ricard, S. et al., A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe, Hum. Mol. Genet., 8(4):567–574, 1999.
    • (1999) Hum. Mol. Genet , vol.8 , Issue.4 , pp. 567-574
    • Abbas, N.1    Lücking, C.B.2    Ricard, S.3
  • 12
    • 0342368772 scopus 로고    scopus 로고
    • Association between Early-Onset Parkinson’s Disease and Mutations in the Parkin Gene
    • Lücking, C. B., Dürr, A., Bonifati, V. et al., Association between Early-Onset Parkinson’s Disease and Mutations in the Parkin Gene, N. Engl. J. Med., 342(21):1560–1567, 2000.
    • (2000) N. Engl. J. Med , vol.342 , Issue.21 , pp. 1560-1567
    • Lücking, C.B.1    Dürr, A.2    Bonifati, V.3
  • 13
    • 0035845715 scopus 로고    scopus 로고
    • Pseudo-dominant inheritance and exon 2 triplication in a family with parkin gene mutations
    • Lücking, C. B., Bonifati, V., Periquet, M., Vanacore, N., Brice, A., Meco, G., Pseudo-dominant inheritance and exon 2 triplication in a family with parkin gene mutations, Neurology, 57(5):924–7, 2001.
    • (2001) Neurology , vol.57 , Issue.5 , pp. 924-927
    • Lücking, C.B.1    Bonifati, V.2    Periquet, M.3    Vanacore, N.4    Brice, A.5    Meco, G.6
  • 14
    • 0035092090 scopus 로고    scopus 로고
    • Origin of the Mutations in the parkin Gene in Europe: Exon Rearrangements Are Independent Recurrent Events, whereas Point Mutations May Result from Founder Effects
    • Periquet, M., Lücking, C. B., Vaughan, J. R. et al., Origin of the Mutations in the parkin Gene in Europe: Exon Rearrangements Are Independent Recurrent Events, whereas Point Mutations May Result from Founder Effects, Am. J. Hum. Genet., 68(3):617–626, 2001.
    • (2001) Am. J. Hum. Genet , vol.68 , Issue.3 , pp. 617-626
    • Periquet, M.1    Lücking, C.B.2    Vaughan, J.R.3
  • 15
    • 0042415580 scopus 로고    scopus 로고
    • How much phenotypic variation can be attributed to parkin genotype
    • Lohmann, E., Periquet, M., Bonifati, V. et al., How much phenotypic variation can be attributed to parkin genotype? Ann. Neurol., 54(2):176–185, 2003.
    • (2003) Ann. Neurol , vol.54 , Issue.2 , pp. 176-185
    • Lohmann, E.1    Periquet, M.2    Bonifati, V.3
  • 16
    • 0342369398 scopus 로고    scopus 로고
    • Levodoparesponsive dystonia: GTP cyclohydrolase I or parkin mutations?
    • Tassin, J., Durr, A., Bonnet, A. M. et al., Levodoparesponsive dystonia: GTP cyclohydrolase I or parkin mutations? Brain, 123 (Pt. 6):1112–1121, 2000.
    • (2000) Brain , vol.123 , pp. 1112-1121
    • Tassin, J.1    Durr, A.2    Bonnet, A.M.3
  • 17
    • 0033849550 scopus 로고    scopus 로고
    • Autosomal recessive early-onset parkinsonism with diurnal fluctuation: Clinicopathologic characteristics and molecular genetic identification
    • Yamamura, Y., Hattori, N., Matsumine, H., Kuzuhara, S., Mizuno, Y., Autosomal recessive early-onset parkinsonism with diurnal fluctuation: Clinicopathologic characteristics and molecular genetic identification, Brain Dev., 22 Suppl., 1:87–91.:87–91, 2000.
    • (2000) Brain Dev , vol.22 , pp. 87-91
    • Yamamura, Y.1    Hattori, N.2    Matsumine, H.3    Kuzuhara, S.4    Mizuno, Y.5
  • 18
    • 0038662544 scopus 로고    scopus 로고
    • Parkin disease: A phenotypic study of a large case series
    • Khan, N. L., Graham, E., Critchley, P. et al., Parkin disease: A phenotypic study of a large case series, Brain, 126 (Pt. 6): 1279–1292, 2003.
    • (2003) Brain , vol.126 , pp. 1279-1292
    • Khan, N.L.1    Graham, E.2    Critchley, P.3
  • 19
    • 0037461313 scopus 로고    scopus 로고
    • Camptocormia, axial dystonia, and parkinsonism: Phenotypic heterogeneity of a parkin mutation
    • Inzelberg, R., Hattori, N., Nisipeanu, P. et al., Camptocormia, axial dystonia, and parkinsonism: Phenotypic heterogeneity of a parkin mutation, Neurology, 60(8):1393–1394, 2003.
    • (2003) Neurology , vol.60 , Issue.8 , pp. 1393-1394
    • Inzelberg, R.1    Hattori, N.2    Nisipeanu, P.3
  • 20
    • 12144288195 scopus 로고    scopus 로고
    • Exerciseinduced dystonia as a preceding symptom of familial Parkinson’s disease
    • Bruno, M. K., Ravina, B., Garraux, G. et al., Exerciseinduced dystonia as a preceding symptom of familial Parkinson’s disease, Mov. Disord., 19(2):228–30, 2004.
    • (2004) Mov. Disord , vol.19 , Issue.2 , pp. 228-230
    • Bruno, M.K.1    Ravina, B.2    Garraux, G.3
  • 21
    • 0034925088 scopus 로고    scopus 로고
    • Homozygous deletion mutation of the parkin gene in patients with atypical parkinsonism
    • Kuroda, Y., Mitsui, T., Akaike, M., Azuma, H., Matsumoto, T., Homozygous deletion mutation of the parkin gene in patients with atypical parkinsonism, J. Neurol. Neurosurg. Psychiatry, 71(2):231–234, 2001.
    • (2001) J. Neurol. Neurosurg. Psychiatry , vol.71 , Issue.2 , pp. 231-234
    • Kuroda, Y.1    Mitsui, T.2    Akaike, M.3    Azuma, H.4    Matsumoto, T.5
  • 22
    • 0037648357 scopus 로고    scopus 로고
    • Parkin mutations are frequent in patients with isolated earlyonset parkinsonism
    • Periquet, M., Latouche, M., Lohmann, E. et al., Parkin mutations are frequent in patients with isolated earlyonset parkinsonism, Brain, 126(Pt 6):1271–1278, 2003.
    • (2003) Brain , vol.126 , pp. 1271-1278
    • Periquet, M.1    Latouche, M.2    Lohmann, E.3
  • 23
    • 0036523867 scopus 로고    scopus 로고
    • Phenotypic variability in a large kindred (Family LA) with deletions in the parkin gene
    • Pramstaller, P. P., Kis, B., Eskelson, C. et al., Phenotypic variability in a large kindred (Family LA) with deletions in the parkin gene, Mov. Disord,. 17(2):424–426, 2002.
    • (2002) Mov. Disord , vol.17 , Issue.2 , pp. 424-426
    • Pramstaller, P.P.1    Kis, B.2    Eskelson, C.3
  • 24
    • 0037461335 scopus 로고    scopus 로고
    • New parkin mutations and atypical phenotypes in families with autosomal recessive parkinsonism
    • Rawal, N., Periquet, M., Lohmann, E. et al., New parkin mutations and atypical phenotypes in families with autosomal recessive parkinsonism, Neurology, 60(8):1378–81, 2003.
    • (2003) Neurology , vol.60 , Issue.8 , pp. 1378-1381
    • Rawal, N.1    Periquet, M.2    Lohmann, E.3
  • 25
    • 0033933192 scopus 로고    scopus 로고
    • Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: Expanding the phenotype
    • Klein, C., Pramstaller, P. P., Kis, B. et al., Parkin deletions in a family with adult-onset, tremor-dominant parkinsonism: Expanding the phenotype, Ann. Neurol., 48(1):65–71, 2000.
    • (2000) Ann. Neurol , vol.48 , Issue.1 , pp. 65-71
    • Klein, C.1    Pramstaller, P.P.2    Kis, B.3
  • 26
    • 0036787533 scopus 로고    scopus 로고
    • Progression of nigrostriatal dysfunction in a parkin kindred: An [18F]dopa PET and clinical study
    • Khan, N. L., Brooks, D. J., Pavese, N. et al., Progression of nigrostriatal dysfunction in a parkin kindred: An [18F]dopa PET and clinical study, Brain, 125 (Pt. 10):2248–2256, 2002.
    • (2002) Brain , vol.125 , pp. 2248-2256
    • Khan, N.L.1    Brooks, D.J.2    Pavese, N.3
  • 27
    • 0035096967 scopus 로고    scopus 로고
    • Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene
    • Hilker, R., Klein, C., Ghaemi, M. et al., Positron emission tomographic analysis of the nigrostriatal dopaminergic system in familial parkinsonism associated with mutations in the parkin gene, Ann. Neurol., 49(3):367–376, 2001.
    • (2001) Ann. Neurol , vol.49 , Issue.3 , pp. 367-376
    • Hilker, R.1    Klein, C.2    Ghaemi, M.3
  • 28
    • 0034848395 scopus 로고    scopus 로고
    • Lewy bodies and parkinsonism in families with parkin mutations
    • Farrer, M., Chan, P., Chen, R. et al., Lewy bodies and parkinsonism in families with parkin mutations, Ann. Neurol., 50(3):293–300, 2001.
    • (2001) Ann. Neurol , vol.50 , Issue.3 , pp. 293-300
    • Farrer, M.1    Chan, P.2    Chen, R.3
  • 29
    • 1342347411 scopus 로고    scopus 로고
    • Parkin variants in North American Parkinson’s disease: Cases and controls
    • Lincoln, S. J., Maraganore, D. M., Lesnick, T. G. et al., Parkin variants in North American Parkinson’s disease: Cases and controls, Mov. Disord., 18(11):1306–11, 2003.
    • (2003) Mov. Disord , vol.18 , Issue.11 , pp. 1306-1311
    • Lincoln, S.J.1    Maraganore, D.M.2    Lesnick, T.G.3
  • 30
    • 0033868381 scopus 로고    scopus 로고
    • Novel mutations, pseudo-dominant inheritance, and possible familial affects in patients with autosomal recessive juvenile parkinsonism
    • Maruyama, M., Ikeuchi, T., Saito, M. et al., Novel mutations, pseudo-dominant inheritance, and possible familial affects in patients with autosomal recessive juvenile parkinsonism, Ann. Neurol., 48(2):245–250, 2000.
    • (2000) Ann. Neurol , vol.48 , Issue.2 , pp. 245-250
    • Maruyama, M.1    Ikeuchi, T.2    Saito, M.3
  • 31
    • 0033539005 scopus 로고    scopus 로고
    • Association of codon 167 Ser/Asn heterozygosity in the parkin gene with sporadic Parkinson’s disease
    • Satoh, J., Kuroda, Y., Association of codon 167 Ser/Asn heterozygosity in the parkin gene with sporadic Parkinson’s disease, Neuroreport., 10(13):2735–2739, 1999.
    • (1999) Neuroreport , vol.10 , Issue.13 , pp. 2735-2739
    • Satoh, J.1    Kuroda, Y.2
  • 32
    • 0042922470 scopus 로고    scopus 로고
    • Coding polymorphisms in the parkin gene and susceptibility to Parkinson disease
    • Lücking, C. B., Chesneau, V., Lohmann, E. et al., Coding polymorphisms in the parkin gene and susceptibility to Parkinson disease, Arch. Neurol., 60(9):1253-1256, 2003.
    • (2003) Arch. Neurol , vol.60 , Issue.9 , pp. 1253-1256
    • Lücking, C.B.1    Chesneau, V.2    Lohmann, E.3
  • 33
    • 0037108727 scopus 로고    scopus 로고
    • Functional association of the parkin gene promoter with idiopathic Parkinson’s disease
    • West, A. B., Maraganore, D., Crook, J. et al., Functional association of the parkin gene promoter with idiopathic Parkinson’s disease, Hum. Mol. Genet., 11(22):2787–2792, 2002.
    • (2002) Hum. Mol. Genet , vol.11 , Issue.22 , pp. 2787-2792
    • West, A.B.1    Maraganore, D.2    Crook, J.3
  • 34
    • 0033946025 scopus 로고    scopus 로고
    • Association studies of Parkinson’s disease and parkin polymorphisms
    • Klein, C., Schumacher, K., Jacobs, H. et al., Association studies of Parkinson’s disease and parkin polymorphisms, Ann. Neurol., 48(1):126–127, 2000.
    • (2000) Ann. Neurol , vol.48 , Issue.1 , pp. 126-127
    • Klein, C.1    Schumacher, K.2    Jacobs, H.3
  • 36
    • 0038375834 scopus 로고    scopus 로고
    • Association study of Parkin gene polymorphisms with idiopathic Parkinson disease
    • Oliveira, S. A., Scott, W. K., Nance, M. A. et al., Association study of Parkin gene polymorphisms with idiopathic Parkinson disease, Arch. Neurol., 60(7):975–980, 2003.
    • (2003) Arch. Neurol , vol.60 , Issue.7 , pp. 975-980
    • Oliveira, S.A.1    Scott, W.K.2    Nance, M.A.3
  • 37
    • 0032937416 scopus 로고    scopus 로고
    • Polymorphism in the parkin gene in sporadic Parkinson’s disease
    • Wang, M., Hattori, N., Matsumine, H. et al., Polymorphism in the parkin gene in sporadic Parkinson’s disease, Ann. Neurol., 45(5):655–658, 1999.
    • (1999) Ann. Neurol , vol.45 , Issue.5 , pp. 655-658
    • Wang, M.1    Hattori, N.2    Matsumine, H.3
  • 38
    • 0035241246 scopus 로고    scopus 로고
    • Prevalence of homozygous deletions of the parkin gene in a cohort of patients with sporadic and familial Parkinson’s disease
    • Ujike, H., Yamamoto, M., Kanzaki, A., Okumura, K., Takaki, M., Kuroda, S., Prevalence of homozygous deletions of the parkin gene in a cohort of patients with sporadic and familial Parkinson’s disease, Mov. Disord., 16(1):111–113, 2001.
    • (2001) Mov. Disord , vol.16 , Issue.1 , pp. 111-113
    • Ujike, H.1    Yamamoto, M.2    Kanzaki, A.3    Okumura, K.4    Takaki, M.5    Kuroda, S.6
  • 39
    • 0028198309 scopus 로고
    • Familial juvenile parkinsonism: Clinical and pathologic study in a family
    • Takahashi, H., Ohama, E., Suzuki, S. et al., Familial juvenile parkinsonism: Clinical and pathologic study in a family, Neurology, 44(3 Pt. 1):437–441, 1994.
    • (1994) Neurology , vol.44 , Issue.3 , pp. 437-441
    • Takahashi, H.1    Ohama, E.2    Suzuki, S.3
  • 40
    • 0035957112 scopus 로고    scopus 로고
    • Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations
    • van De Warrenburg, B. P., Lammens, M., Lücking, C. B. et al., Clinical and pathologic abnormalities in a family with parkinsonism and parkin gene mutations, Neurology, 56(4):555-557, 2001.
    • (2001) Neurology , vol.56 , Issue.4 , pp. 555-557
    • Van De Warrenburg, B.P.1    Lammens, M.2    Lücking, C.B.3
  • 41
    • 0031721141 scopus 로고    scopus 로고
    • Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q
    • Mori, H., Kondo, T., Yokochi, M. et al., Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q, Neurology, 51(3):890-892, 1998.
    • (1998) Neurology , vol.51 , Issue.3 , pp. 890-892
    • Mori, H.1    Kondo, T.2    Yokochi, M.3
  • 42
    • 10744227945 scopus 로고    scopus 로고
    • The C289G and C418R missense mutations cause rapid sequestration of human Parkin into insoluble aggregates
    • Gu, W. J., Corti, O., Araujo, F. et al., The C289G and C418R missense mutations cause rapid sequestration of human Parkin into insoluble aggregates, Neurobiol Dis., 14(3):357–64, 2003.
    • (2003) Neurobiol Dis , vol.14 , Issue.3 , pp. 357-364
    • Gu, W.J.1    Corti, O.2    Araujo, F.3
  • 43
    • 0035954340 scopus 로고    scopus 로고
    • The nigrostriatal dopaminergic system in familial early onset parkinsonism with parkin mutations
    • Portman, A. T., Giladi, N., Leenders, K. L. et al., The nigrostriatal dopaminergic system in familial early onset parkinsonism with parkin mutations, Neurology, 56(12):1759–1762, 2001.
    • (2001) Neurology , vol.56 , Issue.12 , pp. 1759-1762
    • Portman, A.T.1    Giladi, N.2    Leenders, K.L.3
  • 44
    • 0034873177 scopus 로고    scopus 로고
    • Parkinson’s disease: Clinical signs and symptoms, neural mechanisms, positron emission tomography, and therapeutic interventions
    • Leenders, K. L., Oertel, W. H., Parkinson’s disease: Clinical signs and symptoms, neural mechanisms, positron emission tomography, and therapeutic interventions, Neural Plast., 8(1–2):99–110, 2001.
    • (2001) Neural Plast , vol.8 , Issue.1-2 , pp. 99-110
    • Leenders, K.L.1    Oertel, W.H.2
  • 45
    • 0037651048 scopus 로고    scopus 로고
    • Youngonset Parkinson disease with and without parkin gene mutations: A fluorodopa F 18 positron emission tomography study
    • Thobois, S., Ribeiro, M. J., Lohmann, E. et al., Youngonset Parkinson disease with and without parkin gene mutations: A fluorodopa F 18 positron emission tomography study, Arch. Neurol., 60(5):713–718, 2003.
    • (2003) Arch. Neurol , vol.60 , Issue.5 , pp. 713-718
    • Thobois, S.1    Ribeiro, M.J.2    Lohmann, E.3
  • 46
    • 0033933048 scopus 로고    scopus 로고
    • Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase [In Process Citation]
    • Shimura, H., Hattori, N., Kubo, S. et al., Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase [In Process Citation], Nat. Genet., 25(3):302-305, 2000.
    • (2000) Nat. Genet , vol.25 , Issue.3 , pp. 302-305
    • Shimura, H.1    Hattori, N.2    Kubo, S.3
  • 47
    • 0034700158 scopus 로고    scopus 로고
    • Parkin functions as an E2-dependent ubiquitinprotein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
    • Zhang, Y., Gao, J., Chung, K. K., Huang, H., Dawson, V. L., Dawson, T. M., Parkin functions as an E2-dependent ubiquitinprotein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1, Proc. Natl. Acad. Sci., U.S.A., 97(24):13354–13359, 2000.
    • (2000) Proc. Natl. Acad. Sci., U.S.A , vol.97 , Issue.24 , pp. 13354-13359
    • Zhang, Y.1    Gao, J.2    Chung, K.K.3    Huang, H.4    Dawson, V.L.5    Dawson, T.M.6
  • 48
    • 0037378898 scopus 로고    scopus 로고
    • Proteolytic stress: A unifying concept for the etiopathogenesis of Parkinson’s disease
    • McNaught, K. S., Olanow, C. W., Proteolytic stress: A unifying concept for the etiopathogenesis of Parkinson’s disease, Ann. Neurol., 53 Suppl., 3:S73–84; discussion S84–6, 2003.
    • (2003) Ann. Neurol , vol.53 , pp. S84-S86
    • McNaught, K.S.1    Olanow, C.W.2
  • 49
    • 0035854437 scopus 로고    scopus 로고
    • Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson’s disease
    • Shimura, H., Schlossmacher, M. G., Hattori, N. et al., Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson’s disease, Science, 293(5528):263–269, 2001.
    • (2001) Science , vol.293 , Issue.5528 , pp. 263-269
    • Shimura, H.1    Schlossmacher, M.G.2    Hattori, N.3
  • 50
    • 0035967883 scopus 로고    scopus 로고
    • An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
    • Imai, Y., Soda, M., Inoue, H., Hattori, N., Mizuno, Y., Takahashi, R., An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin, Cell, 105(7):891–902, 2001.
    • (2001) Cell , vol.105 , Issue.7 , pp. 891-902
    • Imai, Y.1    Soda, M.2    Inoue, H.3    Hattori, N.4    Mizuno, Y.5    Takahashi, R.6
  • 52
    • 0034776095 scopus 로고    scopus 로고
    • Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease
    • Chung, K. K., Zhang, Y., Lim, K. L. et al., Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease, Nat. Med., 7(10):1144–1150, 2001.
    • (2001) Nat. Med , vol.7 , Issue.10 , pp. 1144-1150
    • Chung, K.K.1    Zhang, Y.2    Lim, K.L.3
  • 53
    • 0037468831 scopus 로고    scopus 로고
    • Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
    • Yang, Y., Nishimura, I., Imai, Y., Takahashi, R., Lu, B., Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila, Neuron, 37(6):911–924, 2003.
    • (2003) Neuron , vol.37 , Issue.6 , pp. 911-924
    • Yang, Y.1    Nishimura, I.2    Imai, Y.3    Takahashi, R.4    Lu, B.5
  • 54
    • 0037338634 scopus 로고    scopus 로고
    • Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
    • Darios, F., Corti, O., Lücking, C. B., et al. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death, Hum. Mol. Genet., 12(5):517–26, 2003.
    • (2003) Hum. Mol. Genet , vol.12 , Issue.5 , pp. 517-526
    • Darios, F.1    Corti, O.2    Lücking, C.B.3
  • 55
    • 0037047311 scopus 로고    scopus 로고
    • Effect of wildtype or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome
    • Hyun, D. H., Lee, M., Hattori, N. et al., Effect of wildtype or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome, J. Biol. Chem., 277(32):28572–7, 2002.
    • (2002) J. Biol. Chem , vol.277 , Issue.32 , pp. 28572-28577
    • Hyun, D.H.1    Lee, M.2    Hattori, N.3
  • 56
    • 0037137702 scopus 로고    scopus 로고
    • Parkin protects against the toxicity associated with mutant alpha-synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons
    • Petrucelli, L., O’Farrell, C., Lockhart, P. J. et al., Parkin protects against the toxicity associated with mutant alpha-synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons, Neuron, 36(6):1007–19, 2002.
    • (2002) Neuron , vol.36 , Issue.6 , pp. 1007-1019
    • Petrucelli, L.1    O’Farrell, C.2    Lockhart, P.J.3
  • 57
    • 0042330407 scopus 로고    scopus 로고
    • Parkin suppresses wild-type alpha-synucleininduced toxicity in SHSY-5Y cells
    • Oluwatosin-Chigbum Y., Robbins, A., Scott, C. W. et al., Parkin suppresses wild-type alpha-synucleininduced toxicity in SHSY-5Y cells, Biochem. Biophys. Res. Commun., 309(3):679-84, 2003.
    • (2003) Biochem. Biophys. Res. Commun , vol.309 , Issue.3 , pp. 679-684
    • Oluwatosin-Chigbum, Y.1    Robbins, A.2    Scott, C.W.3
  • 58
    • 0142242238 scopus 로고    scopus 로고
    • Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain
    • Kim, S. J., Sung, J. Y., Um, J. W. et al., Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain, J. Biol. Chem., 278(43):41890-9, 2003.
    • (2003) J. Biol. Chem , vol.278 , Issue.43 , pp. 41890-41899
    • Kim, S.J.1    Sung, J.Y.2    Um, J.W.3
  • 59
    • 0141891953 scopus 로고    scopus 로고
    • Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
    • Goldberg, M. S., Fleming, S. M., Palacino, J. J. et al., Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons, J. Biol. Chem., 2003.
    • (2003) J. Biol. Chem
    • Goldberg, M.S.1    Fleming, S.M.2    Palacino, J.J.3
  • 60
    • 10744221310 scopus 로고    scopus 로고
    • Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
    • Itier, J. M., Ibanez, P., Mena, M. A. et al., Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse, Hum. Mol. Genet., 12(18):2277–2291, 2003.
    • (2003) Hum. Mol. Genet , vol.12 , Issue.18 , pp. 2277-2291
    • Itier, J.M.1    Ibanez, P.2    Mena, M.A.3
  • 61
    • 2442481789 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative damage in Parkindeficient mice
    • Palacino, J. J., Sagi, D., Goldberg, M. S. et al., Mitochondrial dysfunction and oxidative damage in Parkindeficient mice, J. Biol. Chem, 2004.
    • (2004) J. Biol. Chem
    • Palacino, J.J.1    Sagi, D.2    Goldberg, M.S.3
  • 62
    • 0031711713 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in Parkinson’s disease
    • Mizuno, Y., Yoshino, H., Ikebe, S. et al., Mitochondrial dysfunction in Parkinson’s disease, Ann. Neurol., 44(3 Suppl., 1):S99–109, 1998.
    • (1998) Ann. Neurol , vol.44 , Issue.3 , pp. S99-109
    • Mizuno, Y.1    Yoshino, H.2    Ikebe, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.