Intraoperative cell salvage as an effective intervention for postpartum hemorrhage—Evidence from a prospective randomized controlled trial

Frontiers in Immunology

Volumn 13, Issue , 2022, Pages

  Lei, Bo ^a   Guo, Min ^a   Deng, Xin ^a   He, Shujun ^a   Lu, Xin ^a   Wang, Yunjuan ^a   Wang, Lei ^a  

^a Haidian District Maternal and Child Health Center   (China)

Author keywords

blood transfusion; caesarean section; intraoperative cell salvage; postpartum hemorrhage; pregnancy

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA FETOPROTEIN; ASPARTATE AMINOTRANSFERASE; CALCIUM; CREATININE; ENDOTHELIN 1; HEMOGLOBIN; HEMOGLOBIN F; HEPARIN; POTASSIUM; THROMBOPLASTIN; UREA; FIBRINOGEN;

ACTIVATED PARTIAL THROMBOPLASTIN TIME; ADULT; ANTICOAGULANT THERAPY; APGAR SCORE; ARTICLE; BLOOD CELL COUNT; BLOOD GAS ANALYSIS; CESAREAN SECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE COUNT; ERYTHROCYTE TRANSFUSION; FEMALE; FETUS DISTRESS; HEMATOCRIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIVER FUNCTION TEST; PLACENTA ACCRETA; PLACENTA PREVIA; PLATELET COUNT; POSTPARTUM HEMORRHAGE; PROSPECTIVE STUDY; PROTHROMBIN TIME; RANDOMIZED CONTROLLED TRIAL; THROMBIN TIME; ADVERSE EVENT; CONTROLLED STUDY; PLACENTA; PREGNANCY; PROCEDURES;

ALPHA-FETOPROTEINS; CESAREAN SECTION; FEMALE; FIBRINOGEN; HEMOGLOBINS; HUMANS; PLACENTA; POSTPARTUM HEMORRHAGE; PREGNANCY; PROSPECTIVE STUDIES; THROMBOPLASTIN;

EID: 85140330403     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2022.953334     Document Type: Article

References (25)

1. Say L Chou D Gemmill A Tuncalp O Moller AB Daniels J et al. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health (2014) 2(6):e323-333. doi: 10.1016/S2214-109X(14)70227-X
2. Knight M Callaghan WM Berg C Alexander S Bouvier-Colle MH Ford JB et al. et al: Trends in postpartum hemorrhage in high resource countries: a review and recommendations from the international postpartum hemorrhage collaborative group. BMC Pregn Childbirth (2009) 9:55. doi: 10.1186/1471-2393-9-55
3. Sebghati M Chandraharan E. An update on the risk factors for and management of obstetric haemorrhage. Womens Health (Lond) (2017) 13(2):34–40. doi: 10.1177/1745505717716860
4. Souza JP Gulmezoglu AM Vogel J Carroli G Lumbiganon P Qureshi Z et al. et al: Moving beyond essential interventions for reduction of maternal mortality (the WHO multicountry survey on maternal and newborn health): a cross-sectional study. Lancet (2013) 381(9516):1747–55. doi: 10.1016/S0140-6736(13)60686-8
5. Khan KS Wojdyla D Say L Gulmezoglu AM Van Look PF. WHO analysis of causes of maternal death: a systematic review. Lancet (2006) 367(9516):1066–74. doi: 10.1016/S0140-6736(06)68397-9
6. Li Q Deng D. New medical risks affecting obstetrics after implementation of the two-child policy in China. Front Med (2017) 11(4):570–5. doi: 10.1007/s11684-017-0552-5
7. Raykar NP Makin J Khajanchi M Olayo B Munoz Valencia A Roy N et al. Assessing the global burden of hemorrhage: The global blood supply, deficits, and potential solutions. SAGE Open Med (2021) 9:20503121211054995. doi: 10.1177/20503121211054995
8. DeAndrade D Waters JH Triulzi DJ Alarcon L Wisniewski MK Dyga R et al. Very low rate of patient-related adverse events associated with the use of intraoperative cell salvage. Transfusion (2016) 56(11):2768–72. doi: 10.1111/trf.13791
9. NICE. Blood transfusion (2015). Available at: https://www.nice.org.uk/guidance/ng24/chapter/Recommendations#red-blood-cells-2.
10. Klein AA Bailey CR Charlton AJ Evans E Guckian-Fisher M McCrossan R et al. Association of anaesthetists guidelines: cell salvage for peri-operative blood conservation 2018. Anaesthesia (2018) 73(9):1141–50. doi: 10.1111/anae.14331
11. Campbell JP Mackenzie MJ Yentis SM Sooranna SR Johnson MR. An evaluation of the ability of leucocyte depletion filters to remove components of amniotic fluid. Anaesthesia (2012) 67(10):1152–7. doi: 10.1111/j.1365-2044.2012.07247.x
12. Catling SJ Williams S Fielding AM. Cell salvage in obstetrics: an evaluation of the ability of cell salvage combined with leucocyte depletion filtration to remove amniotic fluid from operative blood loss at caesarean section. Int J Obstet Anesth (1999) 8(2):79–84. doi: 10.1016/s0959-289x(99)80002-8
13. Khan KS Moore PAS Wilson MJ Hooper R Allard S Wrench I et al. et al: Cell salvage and donor blood transfusion during cesarean section: A pragmatic, multicentre randomised controlled trial (SALVO). PloS Med (2017) 14(12):e1002471. doi: 10.1371/journal.pmed.1002471
14. Kenyon C Mallaiah S Djabatey E McNamara H. Association of anaesthetists guidelines on cell salvage - a backward step for obstetric practice? Anaesthesia (2018) 73(12):1574–5. doi: 10.1111/anae.14464
15. Liumbruno GM Liumbruno C Rafanelli D. Autologous blood in obstetrics: where are we going now? Blood Transfus (2012) 10(2):125–47. doi: 10.2450/2011.0010-11
16. Fuller AJ Bucklin BA. Blood product replacement for postpartum hemorrhage. Clin Obstet Gynecol (2010) 53(1):196–208. doi: 10.1097/GRF.0b013e3181cc42a0
17. Liu Y Li X Che X Zhao G Xu M. Intraoperative cell salvage for obstetrics: a prospective randomized controlled clinical trial. BMC Pregn Childbirth (2020) 20(1):452. doi: 10.1186/s12884-020-03138-w
18. Zeng K Huang W Yu C Wang R. How about "The effect of intraoperative cell salvage on allogeneic blood transfusion for patients with placenta accreta"?: an observational study. Med (Baltimore) (2018) 97(22):e10942. doi: 10.1097/MD.0000000000010942
19. Salaria ON Barodka VM Hogue CW Berkowitz DE Ness PM Wasey JO et al. Impaired red blood cell deformability after transfusion of stored allogeneic blood but not autologous salvaged blood in cardiac surgery patients. Anesth Analg (2014) 118(6):1179–87. doi: 10.1213/ANE.0000000000000227
20. Yang JC Sun Y Xu CX Dang QL Li L Xu YG et al. Coagulation defects associated with massive blood transfusion: A large multicenter study. Mol Med Rep (2015) 12(3):4179–86. doi: 10.3892/mmr.2015.3971
21. Kaur K Bhardwaj M Kumar P Singhal S Singh T Hooda S. Amniotic fluid embolism. J Anaesthesiol Clin Pharmacol (2016) 32(2):153–9. doi: 10.4103/0970-9185.173356
22. Lockwood CJ Bach R Guha A Zhou XD Miller WA Nemerson Y. Amniotic fluid contains tissue factor, a potent initiator of coagulation. Am J Obstet Gynecol (1991) 165(5 Pt 1):1335–41. doi: 10.1016/S0002-9378(12)90756-5
23. Bernstein HH Rosenblatt MA Gettes M Lockwood C. The ability of the haemonetics 4 cell saver system to remove tissue factor from blood contaminated with amniotic fluid. Anesth Analg (1997) 85(4):831–3. doi: 10.1213/00000539-199710000-00021
24. Haddow JE Knight GJ Kloza EM Palomaki GE. Alpha-fetoprotein, vaginal bleeding and pregnancy risk. Br J Obstet Gynaecol (1986) 93(6):589–93. doi: 10.1111/j.1471-0528.1986.tb07959.x
25. Sullivan IJ Ralph CJ. Obstetric intra-operative cell salvage and maternal fetal red cell contamination. Transfus Med (2018) 28(4):298–303. doi: 10.1111/tme.12510