Intraarterial thrombolysis in acute ischemic stroke

Stroke: Pathophysiology, Diagnosis, and Management

Volumn , Issue , 2011, Pages 1227-1240

  Furlan, Anthony J ^a   Sharma, Jitendra ^a   Higashida, Randall ^b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85136945397     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-1-4160-5478-8.10062-4     Document Type: Chapter

References (105)

1. Nenci G.G., Gresele P., Taramelli M., et al. Thrombolytic therapy for thromboembolism of vertebrobasilar artery. Angiology 1983, 34:561-571.
2. del Zoppo G.J., Ferbert A., Otis S., et al. Local intra-arterial fibrinolytic therapy in acute carotid territory stroke: A pilot study. Stroke 1988, 19:307-313.
3. Hacke W., Zeumer H., Ferbert A., et al. Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease. Stroke 1988, 19:1216-1222.
4. Accreditation Council for Graduate Medical Education Program Requirements for Residence Education in Endovascular Surgical Neuroradiology Available at. http://www.ACGME.org/RRC_progREQ/%3E.
5. Zeumer H., Freitag H.J., Zanella F., et al. Local intra-arterial fibrinolytic therapy in patients with stroke: Urokinase versus recombinant tissue plasminogen activator (rt-PA). Neuroradiology 1993, 35:159-162.
6. Nesbit G.M., Clark W.M., O'Neil O.R., Barnwell S.L. Intracranial intra-arterial thrombolysis facilitated by microcatheter navigation through an occluded cervical internal carotid artery. J Neurosurg 1996, 84:387-392.
7. Adams H.P., Brott T.C., Furlan A.J., et al. Guidelines for thrombolytic therapy for acute stroke: A supplement to the guidelines for the management of patients with acute ischemic stroke. A Statement for Healthcare Professionals from a Special Writing Group of the Stroke Council, American Heart Association. Stroke 1996, 27:1711-1718.
8. del Zoppo G.J., Higashida R.T., Furlan A.J., et al. PROACT: A Phase II randomized trial of recombinant pro-urokinase by direct arterial delivery in acute middle cerebral artery stroke. Stroke 1998, 29:4-11.
9. Furlan A., Higashida R., Wechsler L., et al. Intra-arterial prourokinase for acute ischemic stroke-The PROACT II Study: A randomized controlled trial. JAMA 1999, 282:2003-2011.
10. Higashida R.T., Halbach V.V., Tsai F.Y., et al. Interventional neurovascular techniques in acute thrombolytic therapy for stroke. Thrombolytic therapy in acute ischemic stroke III. Tokyo 1995, 294-300. Springer-Verlag. T. Yamagushi, E. Mori, K. Minematsu, G.J. del Zoppo (Eds.).
11. Consensus Conference on Current Strategies for Intracerebral Fibrinolysis for Acute Stroke Therapy 2000, Presented at Centocor, Memphis, TN.
12. Abciximab in acute ischemic stroke A randomized, double-blind, placebo-controlled, dose-escalation study. The Abciximab in Ischemic Stroke Investigators. Stroke 2000, 31:601-609.
13. Reperfusion therapy for acute myocardial infarction with fibrinolytic therapy or combination reduced fibrinolytic therapy and platelet glycoprotein IIb/IIIa inhibition: The GUSTO V randomised trial. The GUSTO V Investigators. Lancet 2001, 357:1905-1914.
14. Wallace R.C., Furlan A.J., Moliterno D.J., et al. Basilar artery rethrombosis: Successful treatment with platelet glycoprotein IIb/IIIa receptor inhibitor. Am J Neuroradiol 1997, 18:1257-1260.
15. Qureshi A.I., Suri M.F., Khan J., et al. Abciximab as an adjunct to high-risk carotid or vertebrobasilar angioplasty: Preliminary experience. Neurosurgery 2000, 46:1316-1324.
16. McDonald C.T., O'Donnell J., Bemporad J., et al. The clinical utility of intravenous Integrilin combined with intra-arterial tissue plasminogen activator in acute ischemic stroke: The MGH experience [abstract]. Stroke 2002, 33:359.
17. Credo R.B., Burke S.E., Barker W.M., et al. Recombinant glycosylated pro-urokinase: Biochemistry, pharmacology, and early clinical experience. New therapeutic agents in thrombosis and thrombolysis 1997, 561-589. Marcel Dekker, New York. A.A. Sasahara, J. Loscalzo (Eds.).
18. Hacke W., Kaste M., Fieschi C., et al. Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: The European Cooperative Acute Stroke Study (ECASS). JAMA 1995, 274:1017-1025.
19. The National Institute of Neurological Disorders and Stroke t-PA Stroke Study Group Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995, 333:1581-1587.
20. Clark W.M., Wissman S., Albers G.W., et al. Recombinant tissue plasminogen activator (alteplase) for ischemic stroke 3 to 5 hours after symptom onset-the ATLANTIS Study: A randomized controlled trial. JAMA 1999, 282:2012-2026.
21. Ogawa A., Mori E., Minematsu K., Taki W., et al. for the MELT Japan Study Group: Randomized Trial of Intra-arterial Infusion of Urokinase Within 6 Hours of Middle Cerebral Artery Stroke: The Middle Cerebral Artery Embolism Local Fibrinolytic Intervention Trial (MELT). Japan Stroke 2007, 38:2633-2639.
22. Saqqur M., Uchino K., Demchuk A.M., et al. Site of arterial occlusion identified by transcranial Doppler predicts the response to intravenous thrombolysis for stroke. Stroke 2007, 38:948-954.
23. IMS Study Investigators Combined intravenous and intra-arterial recanalization for acute ischemic stroke: The Interventional Management of Stroke Study. Stroke 2004, 35:904-911.
24. Berlis A., Lutsep H., Barnwell S., et al. Mechanical thrombolysis in acute ischemic stroke with endovascular photoacoustic recanalization. Stroke 2004, 35:1112-1116.
25. Smith W.S., Sung G., Starkman S., et al. MERCI Trial Investigators. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: Results of the MERCI trial. Stroke 2005, 36:1439-1440.
26. Gobin Y.P., Starkman S., Duckwiler G.R., et al. MERCI 1: A phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia. Stroke 2004, 35:2848-2854.
27. Smith W.S., Sung G., Saver J., et al. Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke 2008, 39:1205-1212.
28. Bose A., Henkes H., Alfke K., et al. Penumbra Phase 1 Stroke Trial Investigators: The Penumbra System: a mechanical device for the treatment of acute stroke due to thromboembolism. AJNR Am J Neuroradiol 2008, 29:1409-1413.
29. Penumbra Pivotal Stroke Trial Investigators The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke 2009, 40:2761-2768.
30. Becker K., Brott T. Approval of the MERCI clot retriever: A critical view. Stroke 2005, 36:400-403.
31. Tomsick T. Editorial comment-Mechanical embolus removal: A new day dawning. Stroke 2005, 36:1439-1440.
32. Waugh J.R., Sacharis N. Arteriographic complications in the DSA era. Radiology 1992, 182:243-246.
33. Hacke W., Kaste M., Fieschi C., et al. Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Lancet 1998, 352:1245-1251.
34. Wolpert S.M., Bruckmann H., Greenlee R., et al. Neuroradiologic evaluation of patients with acute stroke treated with recombinant tissue plasminogen activator. AJNR Am J Neuroradiol 1993, 14:3-13.
35. Pessin M., del Zoppo G.J., Furlan A.J. Thrombolytic treatment in acute stroke: Review and update of selective topics. Cerebrovascular diseases: Nineteenth Princeton Stroke Conference 1995, 409-418. Butterworth-Heinemann, Boston. M.A. Moskowitz, L.R. Caplan (Eds.).
36. Hoffman A.I., Lambiase R.E., Haas R.A., et al. Acute vertebrobasilar occlusion: Treatment with high-dose intra-arterial urokinase. AJR Am J Roentgenol 1999, 172:709-712.
37. Katzan I.L., Masaryk T.J., Furlan A.J., et al. Intra-arterial thrombolysis for perioperative stroke after open heart surgery. Neurology 1999, 52:1081-1084.
38. Weber J., Remonda L., Mattle H.P., et al. Selective intra-arterial fibrinolysis of acute central retinal artery occlusion. Stroke 1998, 29:2076-2079.
39. Padolecchia R., Puglioli M., Ragone M.C., et al. Superselective intraarterial fibrinolysis in central retinal artery occlusion. AJNR Am J Neuroradiol 1999, 20:565-567.
40. Lewandowski C.A., Frankel M., Tomsick T.A., et al. Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy for acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial. Stroke 1999, 30:2598-2605.
41. Tomsick T., Broderick J.P., Pancioli A.P., et al. Combined IV-IA rtPA treatment in major acute ischemic stroke [abstract]. Stroke 2002, 33:359.
42. Jansen O., von Kummer R., Forsting M., et al. Thrombolytic therapy in acute occlusion of the intracranial internal carotid artery bifurcation. AJNR Am J Neuroradiol 1995, 16:1977-1986.
43. Brandt T., von Kummer R., Muller-Kuppers M., et al. Thrombolytic therapy of acute basilar artery occlusion. Variables affecting recanalization and outcome. Stroke 1996, 27:875-881.
44. Bruckmann H., Ferbert A., del Zoppo G.J., et al. Acute vertebral-basilar thrombosis. Angiologic-clinical comparison and therapeutic implications. Acta Radiol Suppl 1986, 369:38-42.
45. Hacke W., Schwab S., Horn M., et al. "Malignant" middle cerebral artery territory infarction: Clinical course and prognostic signs. Arch Neurol 1995, 53:309-315.
46. Zaidat O.O., Suarez J.I., Santillan C., et al. Response to intra-arterial and combined intravenous and intra-arterial thrombolytic therapy in patients with distal internal carotid artery occlusion. Stroke 2002, 33:1821-1826.
47. Flint A.C., Duckwiler G.R., Budzik R.F., et al. Mechanical thrombectomy of intracranial internal carotid occlusion: Pooled results of the MERCI and Multi MERCI Part I trials. Stroke 2007, 38:1274-1280.
48. Jovin T.G., Gupta R., Uchino K., et al. Emergent stenting of extracranial internal carotid artery occlusion in acute stroke has a high revascularization rate. Stroke 2005, 36:2426-2430.
49. Levy E., Siddiqui A., Crumlish A., et al. First Food and Drug Administration-Approved Prospective Trial of Primary Intracranial Stenting for Acute Stroke. SARIS (Stent-Assisted Recanalization in Acute Ischemic Stroke), Stroke 2009, 40:3552-3556.
50. Nogueira R., Liebeskind D., Gupta R., et al. Preliminary data for the dawn trial (DWI/PWI and CTP assessment in the triage of wake-up and late presenting strokes undergoing neurointervention): Imaging based endovascular therapy for proximal anterior circulation occlusions beyond 8 h from last seen well in 193 stroke patients. SNIS Annual Meeting oral abstracts. J NeuroInterv Surg 2009, 1:85.
51. Katzan I.L., Furlan A.J. Thrombolytic therapy. Current review of cerebrovascular disease 1999, 185-193. Butterworth Heinemann, Boston. ed 3. M. Fisher, J. Bogousslavsky (Eds.).
52. Cross D.T., Moran C.J., Akins P., et al. Relationship between clot location and outcome after basilar artery thrombolysis. AJNR Am J Neuroradiol 1997, 18:1221-1228.
53. Huemer M., Niederwieser V., Ladurner G. Thrombolytic treatment for acute occlusion of the basilar artery. J Neurol Neurosurg Psychiatry 1995, 58:227-228.
54. Matsumoto K., Satoh K., et al. Intra-arterial therapy in acute ischemic stroke. Thrombolytic therapy in acute ischemic stroke III 1995, 279-287. Springer-Verlag, Tokyo. T. Yamaguchi, E. Mori, K. Minematsu (Eds.).
55. Clark W., Barnwell S., Nesbit G., et al. Efficacy of intra-arterial thrombolysis of basilar artery stroke [abstract]. J Stroke Cerebrovasc Dis 1997, 6:457.
56. Wijdicks E.F., Nichols D.A., Thielen K.R., et al. Intra-arterial thrombolysis in acute basilar artery thromboembolisms: The initial Mayo Clinic experience. Mayo Clin Proc 1997, 72:1005-1013.
57. Herderschee D., Limburg M., Hijdra A., et al. Recombinant tissue plasminogen activator in two patients with basilar artery occlusion. J Neurol Neurosurg Psychiatry 1991, 54:71-73.
58. Zeumer H., Freitag H.J., Grzyska U., et al. Local intra-arterial fibrinolysis in acute vertebrobasilar occlusion. Neuroradiology 1989, 31:336-340.
59. Becker K.J., Monsein L.H., Ulatowski J., et al. Intra-arterial thrombolysis in vertebrobasilar occlusion. AJNR Am J Neuroradiol 1996, 17:255-262.
60. Becker K.J., Purcell L.L., Hacke W., et al. Vertebrobasilar thrombosis: Diagnosis, management, and the use of intra-arterial thrombolytics. Crit Care Med 1996, 24:1729-1742.
61. von Kummer R., Hacke W. Safety and efficacy of intravenous tissue plasminogen activator and heparin in acute middle cerebral artery stroke. Stroke 1992, 23:646-652.
62. Mori E., Yoneda Y., Tabuchi M., et al. Intravenous recombinant tissue plasminogen activator in acute carotid artery territory stroke. Neurology 1992, 42:976-982.
63. Levy D.E., Brott T.G., Haley E.C., et al. Factors related to intracranial hematoma formation in patients receiving tissue-type plasminogen activator for acute ischemic stroke. Stroke 1994, 25:291-297.
64. Kase C.S., Furlan A.J., Wechsler L.R., et al. Hemorrhage after intra-arterial thrombolysis for ischemic stroke: The PROACT II Trial. Neurology 2001, 57:1603-1610.
65. Bozzao L., Angeloni U., Bastianello S., et al. Early angiographic and CT findings in patients with hemorrhagic infarction in the distribution of the middle cerebral artery. AJNR Am J Neuroradiol 1991, 12:1115-1121.
66. Grotta J.C., Choi D., Patel S.C., et al. Agreement and variability in the interpretation of early CT changes in stroke patients qualifying for intravenous tPA therapy. Stroke 1999, 30:1528-1533.
67. Patel S.C., Levine S.R., Tilley J.C., et al. Lack of clinical significance of early ischemic changes on computed tomography in acute stroke. JAMA 2001, 286:2830-2838.
68. Roberts H.C., Dillon W.P., Furlan A.J., et al. Angiographic collaterals in acute stroke-relationship to clinical presentation and outcome: The PROACT II trial [abstract]. Stroke 2001, 32:336.
69. Kidwell C.S., Saver J.L., Duckwiler G., et al. Predictors of hemorrhagic transformation following intra-arterial thrombolysis [abstract]. Stroke 2001, 32:319.
70. Ueda T., Hatakeyama T., Kumon Y., et al. Evaluation of risk of hemorrhagic transformation in local intra-arterial thrombolysis in acute ischemic stroke by initial SPECT. Stroke 1994, 25:298-303.
71. Alexandrov A.V., Bratina P., Grotta J.C. tPA associated reperfusion after acute stroke demonstrated by HMPAO-SPECT [abstract]. Stroke 1998, 7:101-104.
72. Gore J.M., Sloan M., Price T.R., et al. Intracerebral hemorrhage, cerebral infarction, and subdural hematoma after acute myocardial infarction and thrombolytic therapy in the Thrombolysis in Myocardial Infarction Study: Thrombolysis in Myocardial Infarction, Phase II, Pilot and Clinical Trial. Circulation 1991, 83:448-459.
73. Selker H.P., Beshansky J.R., Schmid C.H., et al. Presenting pulse pressure predicts thrombolytic therapy-related intracranial hemorrhage. Thrombolytic Predictive Instrument (TPI) Project Results. Circulation 1994, 90:1657-1661.
74. Simoons M.L., Maggioni A.P., Knatterud G., et al. Individual risk assessment for intracranial haemorrhage during thrombolytic therapy. Lancet 1993, 342:1523-1528.
75. Gebel J.M., Sila C.A., Sloan M.A., et al. Thrombolysis-related intracranial hemorrhage: A radiographic analysis of 244 cases from the Gusto-1 trial with clinical correlation. Stroke 1998, 29:563-569.
76. Larrue V., von Kummer R., del Zoppo G., et al. Hemorrhagic transformation in acute ischemic stroke, potential contributing factors in the European Cooperative Acute Stroke Study. Stroke 1997, 28:957-960.
77. Sloan M.A., Price T.R., Petito C.K., et al. Clinical features and pathogenesis of intracerebral hemorrhage after rt-PA and heparin therapy for acute myocardial infarction: The Thrombolysis in Myocardial Infarction (TIMI) II pilot and randomized clinical trial combined experience. Neurology 1995, 45:649-658.
78. Hacke W. Thrombolysis: Stroke subtype and embolus type. Thrombolytic therapy in acute ischemic stroke II 1993, 153-159. Springer-Verlag, Berlin. G.J. del Zoppo, E. Mori, W. Hacke (Eds.).
79. von Kummer R., Holle R., Rosin L., et al. Does arterial recanalization improve outcome in carotid territory stroke?. Stroke 1995, 26:581-587.
80. Ringelstein E.B., Biniek R., Weiler C., et al. Type and extent of hemispheric brain infarctions and clinical outcome in early and delayed middle cerebral artery recanalization. Neurology 1991, 42:289-298.
81. Chimowitz M., Pessin M., Furlan A., et al. The effect of source of cerebral embolus on susceptibility to thrombolysis [abstract]. Neurology 1994, 44(Suppl 2):A356.
82. Caplan L.R., Mohr J.P., Kistler J.P., Koroshetz W. Thrombolysis-not a panacea for ischemic stroke. N Engl J Med 1997, 337:1309.
83. Wardlaw J.M., Warlow C.P., Counsell C. Systematic review of evidence on thrombolytic therapy for acute ischaemic stroke. Lancet 1997, 350:607-614.
84. Gönner F., Remonda L., Mattle H., et al. Local intra-arterial thrombolysis in acute ischemic stroke. Stroke 1998, 29:1894-1900.
85. Ueda T., Sakaki S., Nochide I., et al. Angioplasty after intra-arterial thrombolysis for acute occlusion of intracranial arteries. Stroke 1998, 29:2568-2574.
86. Mori T., Kazita K., Chokyu K., et al. Short-term arteriographic and clinical outcome after cerebral angioplasty and stenting for intracranial vertebrobasilar and carotid atherosclerotic occlusive disease. AJNR Am J Neuroradiol 2000, 21:249-254.
87. Nakayama T., Tanaka K., Kaneko M., et al. Thrombolysis and angioplasty for acute occlusion of intracranial vertebrobasilar arteries: Report of three cases. J Neurosurg 1998, 88:919-922.
88. Tsai F.Y., Berberaj B., Matovich V., et al. Percutaneous transluminal angioplasty adjunct to thrombolysis for acute middle cerebral artery rethrombosis. AJNR Am J Neuroradiol 1994, 15:1823-1829.
89. Chopko B.W., Kerber C., Wong W., et al. Transcatheter snare removal of acute middle cerebral artery thromboembolism: Technical case report. Neurosurgery 2000, 40:1529-1531.
90. Phatouros C.C., Higashida R.T., Malek A.M., et al. Endovascular stenting of an acutely thrombosed basilar artery: Technical case report and review of the literature. Neurosurgery 1999, 44:667-673.
91. Alexandrov A.V., Demchuk A.M., Felberg R.A., et al. High rate of complete recanalization and dramatic clinical recovery during tPA infusion when continuously monitored with 2-MHz transcranial Doppler monitoring. Stroke 2000, 31:610-614.
92. Lempert T.E., Halbach V.V., Malek A.M., et al. Rescue treatment of acute parent vessel thrombosis with glycoprotein IIb/IIIa inhibitor during GDC coil embolization. Stroke 1999, 30:693-695.
93. Cochrane Database Syst Rev 1999, (4).
94. Emergency interventional stroke therapy A statement from the American Society of Interventional and Therapeutic Neuroradiology and Society of Cardiovascular and Interventional Radiology. Am J Neuroradiol 2001, 22:54.
95. Hirsch J.A., Yoo A.J., Nogueira R.G., et al. Case volumes of intra-arterial and intravenous treatment of ischemic stroke in the USA. J NeuroInterv Surg 2009, 1:27-31.
96. Spodick D.H. Numerators without denominators: There is no FDA for the surgeon. JAMA 1975, 232:35-36.
97. Furlan A.J., Fisher M. Devices, drugs, and the Food and Drug Administration: Increasing implications for ischemic stroke. Stroke 2005, 36:398-399.
98. Furlan A.J. Ethics and feasibility of placebo-controlled interventional acute stroke trials. Stroke 2009, 49:e533-e534.
99. Köhrmann M., Schwab S. Response to letter by Furlan, Stroke. Published online before print 2009.
100. Grotta J, Barreto: A response to letters by Furlan, and Kohrmann and Schwab, Stroke. Published online before print July 23, 2009.
101. Off label practices plague circulatory system device randomized trials. The FDC Reports. The Gray Sheet. Vol 30, May 17, 2004.
102. Meyers P.M., Schumacher H.C., Alexander M.J., et al. Performance and training standards for endovascular ischemic stroke treatment. J NeuroInterv Surg 2009, 1:10-12.
103. Levin S: Concentric Medical: Breaking the stroke device barrier. In Vivo: The Business and Medicine Report, Vol 18, No 9, 2004.
104. Liebeskind D.S. Reversing stroke in the 2010s. Lessons from Desmoteplase in Acute Ischemic Stroke-2 (DIAS-2). Stroke 2009, 40:3156-3158.
105. Soares B.P., Chien J.D., Wintermark M. MR and CT monitoring of recanalization, reperfusion, and penumbra salvage: Everything that recanalizes does not necessarily reperfuse!. Stroke 2009, 40:S24-S27.