메뉴 건너뛰기




Volumn , Issue , 2007, Pages 117-129

Nonimmune heparin-platelet interactions: Implications for the pathogenesis of heparin-induced thrombocytopenia

Author keywords

[No Author keywords available]

Indexed keywords


EID: 85131266474     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter
Times cited : (5)

References (88)
  • 1
    • 0036624483 scopus 로고    scopus 로고
    • Decreased platelet reactivity in blood antic-oagulated with bivalirudin or enoxaparin compared with unfractionated heparin: Implications for coronary intervention
    • Aggarwal A, Sobel BE, Schneider DJ. Decreased platelet reactivity in blood antic-oagulated with bivalirudin or enoxaparin compared with unfractionated heparin: implications for coronary intervention. J Thromb Thrombolysis 13:161-165, 2002.
    • (2002) J Thromb Thrombolysis , vol.13 , pp. 161-165
    • Aggarwal, A.1    Sobel, B.E.2    Schneider, D.J.3
  • 3
    • 0026638091 scopus 로고
    • Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia
    • Amiral J, Bridey F, Dreyfus M, Vissac AM, Fressinaud E, Wolf M, Meyer D. Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia. Thromb Haemost 68:95-96, 1992.
    • (1992) Thromb Haemost , vol.68 , pp. 95-96
    • Amiral, J.1    Bridey, F.2    Dreyfus, M.3    Vissac, A.M.4    Fressinaud, E.5    Wolf, M.6    Meyer, D.7
  • 5
    • 0029887360 scopus 로고    scopus 로고
    • Generation of antibodies to heparin-PF4 complexes without thrombocytopenia in patients treated with unfractionated or low-molecular-weight heparin
    • Amiral J, Peynaud-Debayle E, Wolf M, Bridey F, Vissac AM, Meyer D. Generation of antibodies to heparin-PF4 complexes without thrombocytopenia in patients treated with unfractionated or low-molecular-weight heparin. Am J Hematol 52:90-95, 1996.
    • (1996) Am J Hematol , vol.52 , pp. 90-95
    • Amiral, J.1    Peynaud-Debayle, E.2    Wolf, M.3    Bridey, F.4    Vissac, A.M.5    Meyer, D.6
  • 6
    • 0027172846 scopus 로고
    • Heparin modifies platelet count and function in patients who have undergone thrombolytic therapy for acute myocardial infarction [letter]
    • Balduini CL, Noris P, Bertolino G, Previtali M. Heparin modifies platelet count and function in patients who have undergone thrombolytic therapy for acute myocardial infarction [letter]. Thromb Haemost 69:522-523, 1993.
    • (1993) Thromb Haemost , vol.69 , pp. 522-523
    • Balduini, C.L.1    Noris, P.2    Bertolino, G.3    Previtali, M.4
  • 7
    • 0015529019 scopus 로고
    • Characterization of a chondroitin 4-sulfate proteoglycan carrier for heparin neutralizing activity (platelet factor 4) released from human blood platelets
    • Barber AF, Kaser-Glanzmann R, Jakabova M, Luscher EF. Characterization of a chondroitin 4-sulfate proteoglycan carrier for heparin neutralizing activity (platelet factor 4) released from human blood platelets. Biochim Biophys Acta 286:312-329, 1972.
    • (1972) Biochim Biophys Acta , vol.286 , pp. 312-329
    • Barber, A.F.1    Kaser-Glanzmann, R.2    Jakabova, M.3    Luscher, E.F.4
  • 8
    • 0025991564 scopus 로고
    • Influence on platelet function by heparin in men with unstable coronary artery disease
    • Berglund U, Wallentin L. Influence on platelet function by heparin in men with unstable coronary artery disease. Thromb Haemost 66:648-651, 1991.
    • (1991) Thromb Haemost , vol.66 , pp. 648-651
    • Berglund, U.1    Wallentin, L.2
  • 9
    • 0019192750 scopus 로고
    • The multiple complexes formed by the interaction of platelet factor 4 with heparin
    • Bock PE, Luscombe M, Marshall SE, Pepper DS, Holbrook JJ. The multiple complexes formed by the interaction of platelet factor 4 with heparin. Biochem J 191:769-776, 1980.
    • (1980) Biochem J , vol.191 , pp. 769-776
    • Bock, P.E.1    Luscombe, M.2    Marshall, S.E.3    Pepper, D.S.4    Holbrook, J.J.5
  • 12
    • 0025042191 scopus 로고
    • Heparin-induced platelet aggregation. II. Dose/response relationships for two low molecular weight heparin fractions (CY216 and CY222)
    • Brace LD, Fareed J. Heparin-induced platelet aggregation. II. Dose/response relationships for two low molecular weight heparin fractions (CY216 and CY222). Thromb Res 59:1-14, 1990.
    • (1990) Thromb Res , vol.59 , pp. 1-14
    • Brace, L.D.1    Fareed, J.2
  • 13
    • 0031007008 scopus 로고    scopus 로고
    • The platelet proaggregating and potentiating effects of unfractionated heparin, low molecular weight heparin and heparinoid in intensive care patients and healthy controls
    • Burgess JK, Chong BH. The platelet proaggregating and potentiating effects of unfractionated heparin, low molecular weight heparin and heparinoid in intensive care patients and healthy controls. Eur J Haematol 58:279-285, 1997.
    • (1997) Eur J Haematol , vol.58 , pp. 279-285
    • Burgess, J.K.1    Chong, B.H.2
  • 15
    • 0019986915 scopus 로고
    • The relationship between the hemorrhagic and antithrombotic properties of low molecular weight heparin in rabbits
    • Carter CJ, Kelton JG, Hirsh J, Cerskus A, Santos AV, Gent M. The relationship between the hemorrhagic and antithrombotic properties of low molecular weight heparin in rabbits. Blood 59:1239-1245, 1982.
    • (1982) Blood , vol.59 , pp. 1239-1245
    • Carter, C.J.1    Kelton, J.G.2    Hirsh, J.3    Cerskus, A.4    Santos, A.V.5    Gent, M.6
  • 16
    • 0024021040 scopus 로고
    • Conformational flexibility: A new concept for explaining binding and biological properties of iduronic acid-containing glycosaminoglycans
    • Casu B, Petitou M, Provasoli M, Sinaý P. Conformational flexibility: a new concept for explaining binding and biological properties of iduronic acid-containing glycosaminoglycans. Trends Biochem Sci 13:221-225, 1988.
    • (1988) Trends Biochem Sci , vol.13 , pp. 221-225
    • Casu, B.1    Petitou, M.2    Provasoli, M.3    Sinaý, P.4
  • 17
    • 0026770478 scopus 로고
    • Heparin potentiation of collagen-induced platelet aggregation is related to the GPIIb/GPIIIa receptor and not to the GPIb receptor, as tested by whole blood aggregometry
    • Chen J, Sylvén C. Heparin potentiation of collagen-induced platelet aggregation is related to the GPIIb/GPIIIa receptor and not to the GPIb receptor, as tested by whole blood aggregometry. Thromb Res 66:111-120, 1992.
    • (1992) Thromb Res , vol.66 , pp. 111-120
    • Chen, J.1    Sylvén, C.2
  • 18
    • 0026713034 scopus 로고
    • Heparin enhances platelet aggregation irrespective of anticoagulation with citrate or with hirudin
    • Chen J, Karlberg KE, Sylvén C. Heparin enhances platelet aggregation irrespective of anticoagulation with citrate or with hirudin. Thromb Res 67:253-262,1992.
    • (1992) Thromb Res , vol.67 , pp. 253-262
    • Chen, J.1    Karlberg, K.E.2    Sylvén, C.3
  • 19
    • 0023881365 scopus 로고
    • Heparin-induced thrombocytopenia
    • Chong BH. Heparin-induced thrombocytopenia. Blood Rev 2:108-114, 1988.
    • (1988) Blood Rev , vol.2 , pp. 108-114
    • Chong, B.H.1
  • 20
    • 0020404337 scopus 로고
    • Heparin-induced thrombocytopenia: Association of thrombotic complications with heparin-dependent IgG antibody that induces thromboxane synthesis and platelet aggregation
    • Chong BH, Pitney WR, Castaldi PA. Heparin-induced thrombocytopenia: association of thrombotic complications with heparin-dependent IgG antibody that induces thromboxane synthesis and platelet aggregation. Lancet ii:1246-1248,1982.
    • (1982) Lancet , vol.2 , pp. 1246-1248
    • Chong, B.H.1    Pitney, W.R.2    Castaldi, P.A.3
  • 21
    • 0024449410 scopus 로고
    • The mechanism of heparin-induced platelet aggregation
    • Chong BH, Ismail F. The mechanism of heparin-induced platelet aggregation. Eur J Haematol 43:245-251, 1989.
    • (1989) Eur J Haematol , vol.43 , pp. 245-251
    • Chong, B.H.1    Ismail, F.2
  • 22
    • 0023109003 scopus 로고
    • Immune endothelial-cell injury in heparin-associated thrombocytopenia
    • Cines DB, Tomaski A, Tannenbaum S. Immune endothelial-cell injury in heparin-associated thrombocytopenia. N Engl J Med 316:581-589, 1987.
    • (1987) N Engl J Med , vol.316 , pp. 581-589
    • Cines, D.B.1    Tomaski, A.2    Tannenbaum, S.3
  • 23
    • 0024208853 scopus 로고
    • Effect of heparin and related glycosaminoglycans (GAGs) on thrombin-induced platelet aggregation and release
    • Cofrancesco E, Colombi M, Manfreda M, Pogliani EM. Effect of heparin and related glycosaminoglycans (GAGs) on thrombin-induced platelet aggregation and release. Haematologica 73:471-475, 1988.
    • (1988) Haematologica , vol.73 , pp. 471-475
    • Cofrancesco, E.1    Colombi, M.2    Manfreda, M.3    Pogliani, E.M.4
  • 24
    • 0014224577 scopus 로고
    • Effect of injected heparin on platelet levels in man
    • Davey MG, Lander H. Effect of injected heparin on platelet levels in man. J Clin Pathol 21:55-59, 1968.
    • (1968) J Clin Pathol , vol.21 , pp. 55-59
    • Davey, M.G.1    Lander, H.2
  • 26
    • 0015278353 scopus 로고
    • The platelet aggregating effect of eight commercial heparins
    • Eika C. The platelet aggregating effect of eight commercial heparins. Scand J Haematol 9:480-482, 1972.
    • (1972) Scand J Haematol , vol.9 , pp. 480-482
    • Eika, C.1
  • 27
    • 85088673597 scopus 로고
    • Absence of in vitro cross-reaction of pentasaccharide with the plasma heparin-dependent factor of twenty-five patients with heparin-associated thrombocytopenia
    • Elalamy I, Lecrubier C, Potevin F, Abdelouahed M, Bara L, Marie JP, Samama MM. Absence of in vitro cross-reaction of pentasaccharide with the plasma heparin-dependent factor of twenty-five patients with heparin-associated thrombocytopenia. Thromb Haemost 74:1379-1387, 1995.
    • (1995) Thromb Haemost , vol.74 , pp. 1379-1387
    • Elalamy, I.1    Lecrubier, C.2    Potevin, F.3    Abdelouahed, M.4    Bara, L.5    Marie, J.P.6    Samama, M.M.7
  • 28
    • 0018723409 scopus 로고
    • 2 inhibition of platelet aggregation
    • 2 inhibition of platelet aggregation. Thromb Res 16:617-628, 1979.
    • (1979) Thromb Res , vol.16 , pp. 617-628
    • Eldor, A.1    Weksler, B.B.2
  • 31
    • 0009739078 scopus 로고
    • Heparin-induced thrombocytopenia in man
    • Gollub S, Ulin AW. Heparin-induced thrombocytopenia in man. J Lab Clin Med 59:430-435, 1962.
    • (1962) J Lab Clin Med , vol.59 , pp. 430-435
    • Gollub, S.1    Ulin, A.W.2
  • 32
    • 0027169166 scopus 로고
    • Heparin-associated thrombocytopenia: Immune complexes are attached to the platelet membrane by the negative charge of highly sulphated oligosaccharides
    • Greinacher A, Michels I, Liebenhoff U, Presek P, Mueller-Eckhardt C. Heparin-associated thrombocytopenia: immune complexes are attached to the platelet membrane by the negative charge of highly sulphated oligosaccharides. Br J Haematol 84: 711-716,1993.
    • (1993) Br J Haematol , vol.84 , pp. 711-716
    • Greinacher, A.1    Michels, I.2    Liebenhoff, U.3    Presek, P.4    Mueller-Eckhardt, C.5
  • 35
    • 0023894003 scopus 로고
    • Effects of unfractionated and fractionated heparin on platelet function
    • Heinrich D, Görg T, Schulz M. Effects of unfractionated and fractionated heparin on platelet function. Haemostasis 18:(suppl 3) 48-54, 1988.
    • (1988) Haemostasis , vol.18 , pp. 48-54
    • Heinrich, D.1    Görg, T.2    Schulz, M.3
  • 36
    • 0031871804 scopus 로고    scopus 로고
    • Effect of SR121566A, a potent GP IIb-IIIa antagonist, on the HIT serum/heparin-induced platelet mediated activation of human endothelial cells
    • Herbert J-M, Savi P, Jeske WP, Walenga JM. Effect of SR121566A, a potent GP IIb-IIIa antagonist, on the HIT serum/heparin-induced platelet mediated activation of human endothelial cells. Thromb Haemost 80:326-331, 1998.
    • (1998) Thromb Haemost , vol.80 , pp. 326-331
    • Herbert, J.-M.1    Savi, P.2    Jeske, W.P.3    Walenga, J.M.4
  • 37
    • 0021150941 scopus 로고
    • Heparin induced bleeding
    • Hirsh J. Heparin induced bleeding. Nouv Rev Fr Hematol 26:261-266, 1984.
    • (1984) Nouv Rev Fr Hematol , vol.26 , pp. 261-266
    • Hirsh, J.1
  • 40
    • 0023737074 scopus 로고
    • Heparin binding to normal and abnormal platelets
    • Horne MK III. Heparin binding to normal and abnormal platelets. Thromb Res 51: 135-144, 1988.
    • (1988) Thromb Res , vol.51 , pp. 135-144
    • Horne, M.K.1
  • 41
    • 0025957471 scopus 로고
    • Heparin binds normally to platelets digested with Streptomyces griseus protease
    • Horne MK III. Heparin binds normally to platelets digested with Streptomyces griseus protease. Thromb Res 61:155-158, 1991.
    • (1991) Thromb Res , vol.61 , pp. 155-158
    • Horne, M.K.1
  • 42
    • 0027253281 scopus 로고
    • The effect of secreted heparin-binding proteins on heparin binding to platelets
    • Horne MK III. The effect of secreted heparin-binding proteins on heparin binding to platelets. Thromb Res 70:91-98, 1993.
    • (1993) Thromb Res , vol.70 , pp. 91-98
    • Horne, M.K.1
  • 43
    • 0024313170 scopus 로고
    • Heparin binding to resting and activated platelets
    • Horne MK III, Chao ES. Heparin binding to resting and activated platelets. Blood 74:238-243, 1989.
    • (1989) Blood , vol.74 , pp. 238-243
    • Horne, M.K.1    Chao, E.S.2
  • 44
    • 0025255513 scopus 로고
    • The effect of molecular weight on heparin binding to platelets
    • Horne MK III, Chao ES. The effect of molecular weight on heparin binding to platelets. Br J Haematol 74:306-312, 1990.
    • (1990) Br J Haematol , vol.74 , pp. 306-312
    • Horne, M.K.1    Chao, E.S.2
  • 45
    • 0030136628 scopus 로고    scopus 로고
    • Platelet binding of IgG from patients with heparin-induced thrombocytopenia
    • Horne MK III, Alkins BR. Platelet binding of IgG from patients with heparin-induced thrombocytopenia. J Lab Clin Med 127:435-442, 1996.
    • (1996) J Lab Clin Med , vol.127 , pp. 435-442
    • Horne, M.K.1    Alkins, B.R.2
  • 46
    • 0031949732 scopus 로고    scopus 로고
    • Simultaneous binding of heparin and platelet factor-4 to platelets: Further insights into the mechanism of heparin-induced thrombocytopenia
    • Horne MK III, Hutchison KJ. Simultaneous binding of heparin and platelet factor-4 to platelets: further insights into the mechanism of heparin-induced thrombocytopenia. Am J Hematol 58:24-30, 1998.
    • (1998) Am J Hematol , vol.58 , pp. 24-30
    • Horne, M.K.1    Hutchison, K.J.2
  • 48
    • 0021684552 scopus 로고
    • Heparin-induced thrombocytopenia: A prospective study
    • Johnson RA, Lazarus KH, Henry DH. Heparin-induced thrombocytopenia: a prospective study. Am J Hematol 17:349-353, 1984.
    • (1984) Am J Hematol , vol.17 , pp. 349-353
    • Johnson, R.A.1    Lazarus, K.H.2    Henry, D.H.3
  • 50
    • 0028243705 scopus 로고
    • Immunoglobin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4
    • Kelton JG, Smith JW, Warkentin TE, Hayward CPM, Denomme GA, Horsewood P. Immunoglobin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4. Blood 83:3232-3239, 1994.
    • (1994) Blood , vol.83 , pp. 3232-3239
    • Kelton, J.G.1    Smith, J.W.2    Warkentin, T.E.3    Hayward, C.P.M.4    Denomme, G.A.5    Horsewood, P.6
  • 52
    • 0038506232 scopus 로고    scopus 로고
    • A whole blood flow cytometric determination of platelet activation by unfractionated and low molecular weight heparin in vitro
    • Klein B, Faridi A, von Tempelhoff GH, Heilmann L, Mittermayer C, Rath W. A whole blood flow cytometric determination of platelet activation by unfractionated and low molecular weight heparin in vitro. Thromb Res 108:291-296, 2002.
    • (2002) Thromb Res , vol.108 , pp. 291-296
    • Klein, B.1    Faridi, A.2    von Tempelhoff, G.H.3    Heilmann, L.4    Mittermayer, C.5    Rath, W.6
  • 53
    • 0025766365 scopus 로고
    • Heparin or heparan sulfate - what is the difference?
    • Lindahl U, Kjellén L. Heparin or heparan sulfate - what is the difference? Thromb Haemost 66:44-48,1991.
    • (1991) Thromb Haemost , vol.66 , pp. 44-48
    • Lindahl, U.1    Kjellén, L.2
  • 54
    • 0022262953 scopus 로고
    • The interaction of platelet factor four and glycosaminoglycans
    • Loscalzo J, Melnick B, Handin RI. The interaction of platelet factor four and glycosaminoglycans. Arch Biochem Biophys 240:446-455,1985.
    • (1985) Arch Biochem Biophys , vol.240 , pp. 446-455
    • Loscalzo, J.1    Melnick, B.2    Handin, R.I.3
  • 55
    • 0027442550 scopus 로고
    • Heparin-induced thrombocytopenia (HIT): An overview of 230 patients treated with Orgaran (Org 10172)
    • Magnani HN. Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with Orgaran (Org 10172). Thromb Haemost 70:554-561, 1993.
    • (1993) Thromb Haemost , vol.70 , pp. 554-561
    • Magnani, H.N.1
  • 57
    • 0032728857 scopus 로고    scopus 로고
    • Further characterization of antibody and antigen in heparin-induced thrombocytopenia
    • Newman PM, Chong BH. Further characterization of antibody and antigen in heparin-induced thrombocytopenia. Br J Haematol 107:303-309, 1999.
    • (1999) Br J Haematol , vol.107 , pp. 303-309
    • Newman, P.M.1    Chong, B.H.2
  • 58
    • 0031850163 scopus 로고    scopus 로고
    • Heparin-induced thrombocytopenia: IgG binding to PF4-heparin complexes in the fluid phase and cross-reactivity with low molecular weight heparin and heparinoid
    • Newman PM, Swanson RL, Chong BH. Heparin-induced thrombocytopenia: IgG binding to PF4-heparin complexes in the fluid phase and cross-reactivity with low molecular weight heparin and heparinoid. Thromb Haemost 80:292-297, 1998.
    • (1998) Thromb Haemost , vol.80 , pp. 292-297
    • Newman, P.M.1    Swanson, R.L.2    Chong, B.H.3
  • 59
    • 0021139806 scopus 로고
    • Intra-platelet platelet factor 4 (IP.PF4) and the heparin-mobilisable pool of PF4 in health and atherosclerosis
    • O'Brien JR, Etherington MD, Pashley MA. Intra-platelet platelet factor 4 (IP.PF4) and the heparin-mobilisable pool of PF4 in health and atherosclerosis. Thromb Haemost 51:354-357, 1984.
    • (1984) Thromb Haemost , vol.51 , pp. 354-357
    • O'Brien, J.R.1    Etherington, M.D.2    Pashley, M.A.3
  • 60
    • 0022350389 scopus 로고
    • The heparin-mobilisable pool of platelet factor 4: A comparison of intravenous and subcutaneous heparin and Kabi heparin fragment 2165
    • O'Brien JR, Etherington MD, Pashley MA. The heparin-mobilisable pool of platelet factor 4: a comparison of intravenous and subcutaneous heparin and Kabi heparin fragment 2165. Thromb Haemost 54:735-738, 1985.
    • (1985) Thromb Haemost , vol.54 , pp. 735-738
    • O'Brien, J.R.1    Etherington, M.D.2    Pashley, M.A.3
  • 61
    • 0019904650 scopus 로고
    • Comparison of the in vivo hemorrhagic and antithrombotic effects of a low antithrombin-III affinity heparin fraction
    • Ockelford PA, Carter CJ, Cerskus A, Smith CA, Hirsh J. Comparison of the in vivo hemorrhagic and antithrombotic effects of a low antithrombin-III affinity heparin fraction. Thromb Res 27:679-690, 1982.
    • (1982) Thromb Res , vol.27 , pp. 679-690
    • Ockelford, P.A.1    Carter, C.J.2    Cerskus, A.3    Smith, C.A.4    Hirsh, J.5
  • 64
    • 33644745161 scopus 로고    scopus 로고
    • Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: Diagnostic and therapeutic implications
    • Rauova L, Zhai L, Kowalska MA, Arepally GM, Cines DB, Poncz M. Role of platelet surface PF4 antigenic complexes in heparin-induced thrombocytopenia pathogenesis: diagnostic and therapeutic implications. Blood 107:2346-2353, 2006.
    • (2006) Blood , vol.107 , pp. 2346-2353
    • Rauova, L.1    Zhai, L.2    Kowalska, M.A.3    Arepally, G.M.4    Cines, D.B.5    Poncz, M.6
  • 67
    • 0021176176 scopus 로고
    • Effect of heparin on platelet aggregation
    • Saba HI, Saba SR, Morelli GA. Effect of heparin on platelet aggregation. Am J Hematol 17:295-306, 1984.
    • (1984) Am J Hematol , vol.17 , pp. 295-306
    • Saba, H.I.1    Saba, S.R.2    Morelli, G.A.3
  • 69
    • 79956003736 scopus 로고
    • The use of heparin in blood transfusions
    • Sappington SW. The use of heparin in blood transfusions. JAMA 113:22-25,1939.
    • (1939) JAMA , vol.113 , pp. 22-25
    • Sappington, S.W.1
  • 70
    • 0030012540 scopus 로고    scopus 로고
    • Use of enoxaparin in patients with heparin-induced thrombocytopenia syndrome
    • Slocum MM, Adams JG, Teel R, Spadone DP, Silver D. Use of enoxaparin in patients with heparin-induced thrombocytopenia syndrome. J Vasc Surg 23:839-843, 1996.
    • (1996) J Vasc Surg , vol.23 , pp. 839-843
    • Slocum, M.M.1    Adams, J.G.2    Teel, R.3    Spadone, D.P.4    Silver, D.5
  • 71
    • 0023706045 scopus 로고
    • Characterization of platelet binding of heparins and other glycosaminoglycans
    • Sobel M, Adelman B. Characterization of platelet binding of heparins and other glycosaminoglycans. Thromb Res 50:815-826, 1988.
    • (1988) Thromb Res , vol.50 , pp. 815-826
    • Sobel, M.1    Adelman, B.2
  • 73
    • 0026806511 scopus 로고
    • Localization and characterization of a heparin binding domain peptide of human von Willebrand factor
    • Sobel M, Soler DF, Kermode JC, Harris RB. Localization and characterization of a heparin binding domain peptide of human von Willebrand factor. J Biol Chem 267:8857-8862, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 8857-8862
    • Sobel, M.1    Soler, D.F.2    Kermode, J.C.3    Harris, R.B.4
  • 75
    • 0019729463 scopus 로고
    • Heparin and other sulfated polyanions: Their interaction with the blood platelet
    • Tiffany ML, Penner JA. Heparin and other sulfated polyanions: their interaction with the blood platelet. Ann NY Acad Sci 370:662-667, 1981.
    • (1981) Ann NY Acad Sci , vol.370 , pp. 662-667
    • Tiffany, M.L.1    Penner, J.A.2
  • 76
    • 0024594530 scopus 로고
    • Antithrombotic and bleeding effects of glycosaminoglycans with different degrees of sulfation
    • Van Ryn-McKenna J, Ofosu FA, Hirsh J, Buchanan MR. Antithrombotic and bleeding effects of glycosaminoglycans with different degrees of sulfation. Br J Haematol 71:265-269, 1989.
    • (1989) Br J Haematol , vol.71 , pp. 265-269
    • van Ryn-McKenna, J.1    Ofosu, F.A.2    Hirsh, J.3    Buchanan, M.R.4
  • 77
    • 0028009642 scopus 로고
    • Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells
    • Visentin GP, Ford SE, Scott JP, Aster RH. Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells. J Clin Invest 93:81-88, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 81-88
    • Visentin, G.P.1    Ford, S.E.2    Scott, J.P.3    Aster, R.H.4
  • 78
    • 0030258647 scopus 로고    scopus 로고
    • Patients treated with unfractionated heparin during open heart surgery are at high risk to form antibodies reactive with heparin: Platelet factor 4 complexes
    • Visentin GP, Malik M, Cyganiak KA, Aster RH. Patients treated with unfractionated heparin during open heart surgery are at high risk to form antibodies reactive with heparin: platelet factor 4 complexes. J Lab Clin Med 128:376-383, 1996.
    • (1996) J Lab Clin Med , vol.128 , pp. 376-383
    • Visentin, G.P.1    Malik, M.2    Cyganiak, K.A.3    Aster, R.H.4
  • 79
    • 0030952743 scopus 로고    scopus 로고
    • Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide
    • Walenga JM, Jeske WP, Bara L, Samama MM, Fareed J. Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide. Thromb Res 86:1-36, 1997.
    • (1997) Thromb Res , vol.86 , pp. 1-36
    • Walenga, J.M.1    Jeske, W.P.2    Bara, L.3    Samama, M.M.4    Fareed, J.5
  • 80
    • 0001867030 scopus 로고
    • Platelet morphology, biochemistry, and function
    • Beutler E, Lichtman MA, Coller BS, Kipps TJ, eds. New York: McGraw-Hill
    • Ware AJ, Coller BS. Platelet morphology, biochemistry, and function. In: Beutler E, Lichtman MA, Coller BS, Kipps TJ, eds. Williams Hematology, fifth edition. New York: McGraw-Hill, 1161-1201, 1995.
    • (1995) Williams Hematology, fifth edition , pp. 1161-1201
    • Ware, A.J.1    Coller, B.S.2
  • 82
    • 0029035681 scopus 로고
    • Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin
    • Warkentin TE, Levine MN, Hirsh J, Horsewood P, Roberts RS, Gent M, Kelton JG. Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 332:1330-1335, 1995.
    • (1995) N Engl J Med , vol.332 , pp. 1330-1335
    • Warkentin, T.E.1    Levine, M.N.2    Hirsh, J.3    Horsewood, P.4    Roberts, R.S.5    Gent, M.6    Kelton, J.G.7
  • 85
    • 28444494385 scopus 로고    scopus 로고
    • Anti-platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin
    • Warkentin TE, Cook RJ, Marder VJ, Sheppard JI, Moore JC, Eriksson BI, Greinacher A, Kelton JG. Anti-platelet factor 4/heparin antibodies in orthopedic surgery patients receiving antithrombotic prophylaxis with fondaparinux or enoxaparin. Blood 106:3791-3796, 2005.
    • (2005) Blood , vol.106 , pp. 3791-3796
    • Warkentin, T.E.1    Cook, R.J.2    Marder, V.J.3    Sheppard, J.I.4    Moore, J.C.5    Eriksson, B.I.6    Greinacher, A.7    Kelton, J.G.8
  • 86
    • 0022899526 scopus 로고
    • Comparison of the effects of low molecular weight heparin and unfractionated heparin on activation of human platelets in vitro
    • Westwick J, Scully MF, Poll C, Kakkar VV. Comparison of the effects of low molecular weight heparin and unfractionated heparin on activation of human platelets in vitro. Thromb Res 42:435-447, 1986.
    • (1986) Thromb Res , vol.42 , pp. 435-447
    • Westwick, J.1    Scully, M.F.2    Poll, C.3    Kakkar, V.V.4
  • 87
    • 0345487533 scopus 로고    scopus 로고
    • Platelet activation with unfractionated heparin at therapeutic concentrations and comparisons with a low-molecular-weight heparin and with a direct thrombin inhibitor
    • Xiao Z, Théroux P. Platelet activation with unfractionated heparin at therapeutic concentrations and comparisons with a low-molecular-weight heparin and with a direct thrombin inhibitor. Circulation 97:251-256, 1998.
    • (1998) Circulation , vol.97 , pp. 251-256
    • Xiao, Z.1    Théroux, P.2
  • 88
    • 0028211342 scopus 로고
    • Ex-vivo and in-vitro evidence that low molecular weight heparins exhibit less binding to plasma proteins than unfractionated heparin
    • Young E, Wells P, Holloway S, Weitz J, Hirsh J. Ex-vivo and in-vitro evidence that low molecular weight heparins exhibit less binding to plasma proteins than unfractionated heparin. Thromb Haemost 71:300-304, 1994.
    • (1994) Thromb Haemost , vol.71 , pp. 300-304
    • Young, E.1    Wells, P.2    Holloway, S.3    Weitz, J.4    Hirsh, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.