메뉴 건너뛰기




Volumn 146, Issue 1, 2020, Pages 110-118

Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan

Author keywords

COVID 19; mortality; risk factors; SARS CoV 2; severity

Indexed keywords

ALPHA INTERFERON; CORTICOSTEROID; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 6; LACTATE DEHYDROGENASE; LOPINAVIR PLUS RITONAVIR; OSELTAMIVIR; RIBAVIRIN; TUMOR NECROSIS FACTOR; UMIFENOVIR;

EID: 85083786720     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2020.04.006     Document Type: Article
Times cited : (1734)

References (32)
  • 1
    • 85078741591 scopus 로고    scopus 로고
    • Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
    • Lu, R., Zhao, X., Li, J., Niu, P., Yang, B., Wu, H., et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet 395 (2020), 565–574.
    • (2020) Lancet , vol.395 , pp. 565-574
    • Lu, R.1    Zhao, X.2    Li, J.3    Niu, P.4    Yang, B.5    Wu, H.6
  • 2
    • 0346456011 scopus 로고    scopus 로고
    • Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003
    • Available at: Accessed March 22, 2020
    • World Health Organization. Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003. Available at: https://www.who.int/csr/sars/country/table2004_04_21/en/ Accessed March 22, 2020.
  • 3
    • 84882655680 scopus 로고    scopus 로고
    • Middle East respiratory syndrome coronavirus (MERS-CoV)
    • Available at: Accessed March 22, 2020
    • World Health Organization. Middle East respiratory syndrome coronavirus (MERS-CoV). Available at: http://www.who.int/emergencies/mers-cov/en/ Accessed March 22, 2020.
  • 4
    • 85078227553 scopus 로고    scopus 로고
    • Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected: interim guidance
    • Available at: Accessed March 22, 2020
    • World Health Organization. Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected: interim guidance. Available at: https://www.who.int/internal-publications-detail/clinical-managementof-severe-acute-respiratory-infection-when-novel-coronavirus-(ncov)-infection-is-suspected Accessed March 22, 2020.
  • 5
    • 85078905787 scopus 로고    scopus 로고
    • Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases
    • Available at: Accessed March 22, 2020
    • World Health Organization. Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases. Available at: https://www.who.int/publications-detail/laboratory-testing-for-2019-novel-coronavirus-in-suspected-human-cases-20200117 Accessed March 22, 2020.
  • 6
    • 85072774669 scopus 로고    scopus 로고
    • Diagnosis and treatment of adults with community-acquired pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America
    • Metlay, J.P., Waterer, G.W., Long, A.C., Anzueto, A., Brozek, J., Crothers, K., et al. Diagnosis and treatment of adults with community-acquired pneumonia. An Official Clinical Practice Guideline of the American Thoracic Society and Infectious Diseases Society of America. Am J Respir Crit Care Med 200 (2019), e45–e67.
    • (2019) Am J Respir Crit Care Med , vol.200 , pp. e45-e67
    • Metlay, J.P.1    Waterer, G.W.2    Long, A.C.3    Anzueto, A.4    Brozek, J.5    Crothers, K.6
  • 7
    • 85078262578 scopus 로고    scopus 로고
    • Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
    • Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 395 (2020), 497–506.
    • (2020) Lancet , vol.395 , pp. 497-506
    • Huang, C.1    Wang, Y.2    Li, X.3    Ren, L.4    Zhao, J.5    Hu, Y.6
  • 8
    • 85081266700 scopus 로고    scopus 로고
    • Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention [published online ahead of print February 24, 2020]. JAMA.
    • Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention [published online ahead of print February 24, 2020]. JAMA. https://doi.org/10.1001/jama.2020.2648.
    • Wu, Z.1    McGoogan, J.M.2
  • 9
    • 85083241171 scopus 로고    scopus 로고
    • Clinical characteristics of coronavirus disease 2019 in China [published online ahead of print February 28, 2020]. N Engl J Med.
    • Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical characteristics of coronavirus disease 2019 in China [published online ahead of print February 28, 2020]. N Engl J Med. https://doi.org/10.1056/NEJMoa2002032.
    • Guan, W.J.1    Ni, Z.Y.2    Hu, Y.3    Liang, W.H.4    Ou, C.Q.5    He, J.X.6
  • 10
    • 33750521184 scopus 로고    scopus 로고
    • Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS
    • He, L., Ding, Y., Zhang, Q., Che, X., He, Y., Shen, H., et al. Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS. J Pathol 210 (2006), 288–297.
    • (2006) J Pathol , vol.210 , pp. 288-297
    • He, L.1    Ding, Y.2    Zhang, Q.3    Che, X.4    He, Y.5    Shen, H.6
  • 11
    • 23944516947 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome: clinical and laboratory manifestations
    • Lam, C.W., Chan, M.H., Wong, C.K., Severe acute respiratory syndrome: clinical and laboratory manifestations. Clin Biochem Rev 25 (2004), 121–132.
    • (2004) Clin Biochem Rev , vol.25 , pp. 121-132
    • Lam, C.W.1    Chan, M.H.2    Wong, C.K.3
  • 12
    • 33644875732 scopus 로고    scopus 로고
    • Clinical manifestations and inflammatory cytokine responses in patients with severe acute respiratory syndrome
    • Sheng, W.H., Chiang, B.L., Chang, S.C., Ho, H.N., Wang, J.T., Chen, Y.C., et al. Clinical manifestations and inflammatory cytokine responses in patients with severe acute respiratory syndrome. J Formos Med Assoc 104 (2005), 715–723.
    • (2005) J Formos Med Assoc , vol.104 , pp. 715-723
    • Sheng, W.H.1    Chiang, B.L.2    Chang, S.C.3    Ho, H.N.4    Wang, J.T.5    Chen, Y.C.6
  • 13
    • 32944476100 scopus 로고    scopus 로고
    • SARS immunity and vaccination
    • Zhu, M., SARS immunity and vaccination. Cell Mol Immunol 1 (2004), 193–198.
    • (2004) Cell Mol Immunol , vol.1 , pp. 193-198
    • Zhu, M.1
  • 14
    • 85069903842 scopus 로고    scopus 로고
    • Prevalence, risk factors, and management of asthma in China: a national cross-sectional study
    • Huang, K., Yang, T., Xu, J., Yang, L., Zhao, J., Zhang, X., et al. Prevalence, risk factors, and management of asthma in China: a national cross-sectional study. Lancet 394 (2019), 407–418.
    • (2019) Lancet , vol.394 , pp. 407-418
    • Huang, K.1    Yang, T.2    Xu, J.3    Yang, L.4    Zhao, J.5    Zhang, X.6
  • 15
    • 85080137864 scopus 로고    scopus 로고
    • Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China [published online ahead of print February 19, 2020]. Allergy.
    • Zhang JJ, Dong X, Cao YY, Yuan YD, Yang YB, Yan YQ, et al. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China [published online ahead of print February 19, 2020]. Allergy. https://doi.org/10.1111/all.14238.
    • Zhang, J.J.1    Dong, X.2    Cao, Y.Y.3    Yuan, Y.D.4    Yang, Y.B.5    Yan, Y.Q.6
  • 16
    • 84963655949 scopus 로고    scopus 로고
    • An increased prevalence of self-reported allergic rhinitis in major Chinese cities from 2005 to 2011
    • Wang, X.D., Zheng, M., Lou, H.F., Wang, C.S., Zhang, Y., Bo, M.Y., et al. An increased prevalence of self-reported allergic rhinitis in major Chinese cities from 2005 to 2011. Allergy 71 (2016), 1170–1180.
    • (2016) Allergy , vol.71 , pp. 1170-1180
    • Wang, X.D.1    Zheng, M.2    Lou, H.F.3    Wang, C.S.4    Zhang, Y.5    Bo, M.Y.6
  • 17
    • 84864270714 scopus 로고    scopus 로고
    • ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation
    • Hashimoto, T., Perlot, T., Rehman, A., Trichereau, J., Ishiguro, H., Paolino, M., et al. ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature 487 (2012), 477–481.
    • (2012) Nature , vol.487 , pp. 477-481
    • Hashimoto, T.1    Perlot, T.2    Rehman, A.3    Trichereau, J.4    Ishiguro, H.5    Paolino, M.6
  • 18
    • 85081978952 scopus 로고    scopus 로고
    • Specific ACE2 expression in cholangiocytes may cause liver damage after 2019-nCoV infection
    • 2020.02.03.931766
    • Chai, X., Hu, L., Zhang, Y., Han, W., Lu, Z., Ke, A., et al. Specific ACE2 expression in cholangiocytes may cause liver damage after 2019-nCoV infection. bioRxiv, 2020 2020.02.03.931766.
    • (2020) bioRxiv
    • Chai, X.1    Hu, L.2    Zhang, Y.3    Han, W.4    Lu, Z.5    Ke, A.6
  • 19
    • 77955664058 scopus 로고    scopus 로고
    • Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes
    • Yang, J.K., Lin, S.S., Ji, X.J., Guo, L.M., Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes. Acta Diabetol 47 (2010), 193–199.
    • (2010) Acta Diabetol , vol.47 , pp. 193-199
    • Yang, J.K.1    Lin, S.S.2    Ji, X.J.3    Guo, L.M.4
  • 20
    • 85081683293 scopus 로고    scopus 로고
    • Xia Ja, Zhou X, Xu S, Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China [published online ahead of print March 13, 2020]. JAMA Intern Med.
    • Wu C, Chen X, Cai Y, Xia Ja, Zhou X, Xu S, et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China [published online ahead of print March 13, 2020]. JAMA Intern Med. https://doi.org/10.1001/jamainternmed.2020.0994.
    • Wu, C.1    Chen, X.2    Cai, Y.3
  • 21
    • 85083215090 scopus 로고    scopus 로고
    • Comorbidity and its impact on 1590 patients with Covid-19 in China: a nationwide analysis [published online ahead of print March 26, 2020]. Eur Respir J.
    • Guan WJ, Liang WH, Zhao Y, Liang HR, Chen ZS, Li YM, et al. Comorbidity and its impact on 1590 patients with Covid-19 in China: a nationwide analysis [published online ahead of print March 26, 2020]. Eur Respir J. https://doi.org/10.1183/13993003.00547-2020.
    • Guan, W.J.1    Liang, W.H.2    Zhao, Y.3    Liang, H.R.4    Chen, Z.S.5    Li, Y.M.6
  • 22
    • 21844460785 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 protects from severe acute lung failure
    • Imai, Y., Kuba, K., Rao, S., Huan, Y., Guo, F., Guan, B., et al. Angiotensin-converting enzyme 2 protects from severe acute lung failure. Nature 436 (2005), 112–116.
    • (2005) Nature , vol.436 , pp. 112-116
    • Imai, Y.1    Kuba, K.2    Rao, S.3    Huan, Y.4    Guo, F.5    Guan, B.6
  • 23
    • 23844463115 scopus 로고    scopus 로고
    • A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury
    • Kuba, K., Imai, Y., Rao, S., Gao, H., Guo, F., Guan, B., et al. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. Nat Med 11 (2005), 875–879.
    • (2005) Nat Med , vol.11 , pp. 875-879
    • Kuba, K.1    Imai, Y.2    Rao, S.3    Gao, H.4    Guo, F.5    Guan, B.6
  • 24
    • 0037142101 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 is an essential regulator of heart function
    • Crackower, M.A., Sarao, R., Oudit, G.Y., Yagil, C., Kozieradzki, I., Scanga, S.E., et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 417 (2002), 822–828.
    • (2002) Nature , vol.417 , pp. 822-828
    • Crackower, M.A.1    Sarao, R.2    Oudit, G.Y.3    Yagil, C.4    Kozieradzki, I.5    Scanga, S.E.6
  • 25
    • 84905645098 scopus 로고    scopus 로고
    • Diagnostic and prognostic value of very high serum lactate dehydrogenase in admitted medical patients
    • Erez, A., Shental, O., Tchebiner, J.Z., Laufer-Perl, M., Wasserman, A., Sella, T., et al. Diagnostic and prognostic value of very high serum lactate dehydrogenase in admitted medical patients. Isr Med Assoc J 16 (2014), 439–443.
    • (2014) Isr Med Assoc J , vol.16 , pp. 439-443
    • Erez, A.1    Shental, O.2    Tchebiner, J.Z.3    Laufer-Perl, M.4    Wasserman, A.5    Sella, T.6
  • 26
    • 85081901579 scopus 로고    scopus 로고
    • Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
    • Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 395 (2020), 1054–1062.
    • (2020) Lancet , vol.395 , pp. 1054-1062
    • Zhou, F.1    Yu, T.2    Du, R.3    Fan, G.4    Liu, Y.5    Liu, Z.6
  • 27
    • 85079841872 scopus 로고    scopus 로고
    • Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study [published online ahead of print February 24, 2020]. Lancet Respir Med.
    • Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study [published online ahead of print February 24, 2020]. Lancet Respir Med. https://doi.org/10.1016/S2213-2600(20)30079-5.
    • Yang, X.1    Yu, Y.2    Xu, J.3    Shu, H.4    Xia, J.5    Liu, H.6
  • 28
    • 85082474264 scopus 로고    scopus 로고
    • A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 [published online ahead of print March 18, 2020]. N Engl J Med.
    • Cao B, Wang Y, Wen D, Liu W, Wang J, Fan G, et al. A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 [published online ahead of print March 18, 2020]. N Engl J Med. https://doi.org/10.1056/NEJMoa2001282.
    • Cao, B.1    Wang, Y.2    Wen, D.3    Liu, W.4    Wang, J.5    Fan, G.6
  • 29
    • 85078241697 scopus 로고    scopus 로고
    • A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
    • Chan, J.F., Yuan, S., Kok, K.H., To, K.K., Chu, H., Yang, J., et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 395 (2020), 514–523.
    • (2020) Lancet , vol.395 , pp. 514-523
    • Chan, J.F.1    Yuan, S.2    Kok, K.H.3    To, K.K.4    Chu, H.5    Yang, J.6
  • 30
    • 85078852923 scopus 로고    scopus 로고
    • Transmission of 2019-nCoV infection from an asymptomatic contact in Germany
    • Rothe, C., Schunk, M., Sothmann, P., Bretzel, G., Froeschl, G., Wallrauch, C., et al. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. N Engl J Med 382 (2020), 970–971.
    • (2020) N Engl J Med , vol.382 , pp. 970-971
    • Rothe, C.1    Schunk, M.2    Sothmann, P.3    Bretzel, G.4    Froeschl, G.5    Wallrauch, C.6
  • 31
    • 85081698917 scopus 로고    scopus 로고
    • Positive RT-PCR test results in patients recovered from COVID-19 [published online ahead of print February 27, 2020]. JAMA.
    • Lan L, Xu D, Ye G, Xia C, Wang S, Li Y, et al. Positive RT-PCR test results in patients recovered from COVID-19 [published online ahead of print February 27, 2020]. JAMA. https://doi.org/10.1001/jama.2020.2783.
    • Lan, L.1    Xu, D.2    Ye, G.3    Xia, C.4    Wang, S.5    Li, Y.6
  • 32
    • 85082122201 scopus 로고    scopus 로고
    • The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned? [published online ahead of print February 22, 2020] Int J Epidemiol.
    • Peeri NC, Shrestha N, Rahman MS, Zaki R, Tan Z, Bibi S, et al. The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned? [published online ahead of print February 22, 2020] Int J Epidemiol. https://doi.org/10.1093/ije/dyaa033.
    • Peeri, N.C.1    Shrestha, N.2    Rahman, M.S.3    Zaki, R.4    Tan, Z.5    Bibi, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.