Association Between Cardiac Injury and Mortality in Hospitalized Patients Infected With Avian Influenza A (H7N9) Virus

Critical Care Medicine

Volumn 48, Issue 4, 2020, Pages 451-458

  Gao, Chang ^a,b   Wang, Yeming ^c   Gu, Xiaoying ^d   Shen, Xinghua ^e   Zhou, Daming ^f   Zhou, Shujun ^g   Huang, Jian An ^b,h,i   Cao, Bin ^c   Guo, Qiang ^b  

^a The First Affiliated Hospital of Soochow University   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^e PEKING UNION MEDICAL COLLEGE   (China)

^f The Affiliated Infectious Diseases Hospital of Soochow University   (China)

^g Taizhou People's Hospital   (China)

^h THE THIRD AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

ⁱ PEKING UNIVERSITY   (China)

Author keywords

avian influenza A (H7N9); cardiac injury; mortality

Indexed keywords

ADULT; AGE; CHINA; CORONAVIRUS INFECTION; CRITICAL ILLNESS; FEMALE; HEART INJURY; HUMAN; INFLUENZA; INFLUENZA A VIRUS (H7N9); ISOLATION AND PURIFICATION; MALE; MIDDLE AGED; MORTALITY; RESPIRATORY DISTRESS SYNDROME; RETROSPECTIVE STUDY; SOCIOECONOMICS; VIROLOGY;

ADULT; AGE FACTORS; CHINA; CORONAVIRUS INFECTIONS; CRITICAL ILLNESS; FEMALE; HEART INJURIES; HUMANS; INFLUENZA A VIRUS, H7N9 SUBTYPE; INFLUENZA, HUMAN; MALE; MIDDLE AGED; RESPIRATORY DISTRESS SYNDROME; RETROSPECTIVE STUDIES; SOCIOECONOMIC FACTORS;

EID: 85079055814     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000004207     Document Type: Article

References (47)

1. Wang X, Jiang H, Wu P,. Epidemiology of avian influenza A H7N9 virus in human beings across five epidemics in mainland China, 2013-17: an epidemiological study of laboratory-confirmed case series. Lancet Infect Dis 2017; 17: 822-832
2. Yu D, Xiang G, Zhu W,. The re-emergence of highly pathogenic avian influenza H7N9 viruses in humans in mainland China, 2019. Euro Surveill 2019; (21): 1900273
3. Gao HN, Lu HZ, Cao B,. Clinical findings in 111 cases of influenza A (H7N9) virus infection. N Engl J Med 2013; 368: 2277-2285
4. Oseasohn R, Adelson L, Kaji M,. Clinicopathologic study of thirty-three fatal cases of Asian influenza. N Engl J Med 1959; 260: 509-518
5. Verel D, Warrack AJ, Potter CW,. Observations on the A2 England influenza epidemic: A clinicopathological study. Am Heart J 1976; 92: 290-296
6. Erden I, Erden EC, Ozhan H,. Echocardiographic manifestations of pandemic 2009 (H1N1) influenza a virus infection. J Infect 2010; 61: 60-65
7. Haessler S, Paez A, Rothberg M,. 2009 pandemic H1N1-associated myocarditis in a previously healthy adult. Clin Microbiol Infect 2011; 17: 572-574
8. Kumar K, Guirgis M, Zieroth S,. Influenza myocarditis and myositis: Case presentation and review of the literature. Can J Cardiol 2011; 27: 514-522
9. Chacko B, Peter JV, Pichamuthu K,. Cardiac manifestations in patients with pandemic (H1N1) 2009 virus infection needing intensive care. J Crit Care 2012; 27: 106 e101-106.e101
10. Jeyanathan T, Overgaard C, McGeer A,. Cardiac complications of influenza infection in 3 adults. CMAJ 2013; 185: 581-584
11. Kwong JC, Schwartz KL, Campitelli MA,. Acute myocardial infarction after laboratory-confirmed influenza infection. N Engl J Med 2018; 378: 345-353
12. Wang J, Xu H, Yang X,. Cardiac complications associated with the influenza viruses A subtype H7N9 or pandemic H1N1 in critically ill patients under intensive care. Braz J Infect Dis 2017; 21: 12-18
13. Gurevich VS,. Influenza, autoimmunity and atherogenesis. Autoimmun Rev 2005; 4: 101-105
14. Mamas MA, Fraser D, Neyses L,. Cardiovascular manifestations associated with influenza virus infection. Int J Cardiol 2008; 130: 304-309
15. Estabragh ZR, Mamas MA,. The cardiovascular manifestations of influenza: a systematic review. Int J Cardiol 2013; 167: 2397-2403
16. Wang Y, Guo Q, Yan Z, CAP-China Network: Factors associated with prolonged viral shedding in patients with avian influenza A(H7N9) virus infection. J Infect Dis 2018; 217: 1708-1717
17. Li Q, Zhou L, Zhou M,. Epidemiology of human infections with avian influenza A(H7N9) virus in China. N Engl J Med 2014; 370: 520-532
18. Warren-Gash C, Smeeth L, Hayward AC,. Influenza as a trigger for acute myocardial infarction or death from cardiovascular disease: A systematic review. Lancet Infect Dis 2009; 9: 601-610
19. Thygesen K, Alpert JS, Jaffe AS, Executive Group on behalf of the Joint European Society of Cardiology (ESC)/American College of Cardiology (ACC)/American Heart Association (AHA)/World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction: Fourth Universal Definition of Myocardial Infarction (2018). Circulation 2018; 138: e618-e651
20. Ito T, Akamatsu K, Ukimura A,. The prevalence and findings of subclinical influenza-associated cardiac abnormalities among Japanese patients. Intern Med 2018; 57: 1819-1826
21. Er F, Ederer S, Nia AM,. Accuracy of Doppler-echocardiographic mean pulmonary artery pressure for diagnosis of pulmonary hypertension. PLoS One 2010; 5: e15670
22. Rudski LG, Lai WW, Afilalo J,. Guidelines for the echocardiographic assessment of the right heart in adults: A report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr 2010, 23: 685-713; quiz 786 688
23. Galiè N, Humbert M, Vachiery JL, ESC Scientific Document Group: 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Heart J 2016; 37: 67-119
24. Ranieri VM, Rubenfeld GD, Thompson BT, ARDS Definition Task Force: Acute respiratory distress syndrome: the Berlin Definition. JAMA 2012; 307: 2526-2533
25. Khwaja A,. KDIGO clinical practice guidelines for acute kidney injury. Nephron Clin Pract 2012; 120: c179-c184
26. Tang BM, Craig JC, Eslick GD,. Use of corticosteroids in acute lung injury and acute respiratory distress syndrome: A systematic review and meta-analysis. Crit Care Med 2009; 37: 1594-1603
27. Cao B, Gao H, Zhou B,. Adjuvant corticosteroid treatment in adults with influenza a (H7N9) viral pneumonia. Crit Care Med 2016; 44: e318-e328
28. Geladari E, Papademetriou V, Moore H,. A case of influenza type a myocarditis that presents with ST elevation MI, cardiogenic shock, acute renal failure, and rhabdomyolysis and with rapid recovery after treatment with oseltamivir and intra-aortic balloon pump support. Cardiovasc Revasc Med 2018; 19: 37-42
29. Ludwig A, Lucero-Obusan C, Schirmer P,. Acute cardiac injury events ≤30 days after laboratory-confirmed influenza virus infection among U.S. veterans, 2010-2012. BMC Cardiovasc Disord 2015; 15: 109
30. Mercat A, Richard JC, Vielle B, Expiratory Pressure (Express) Study Group: Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: A randomized controlled trial. JAMA 2008; 299: 646-655
31. Han J, Mou Y, Yan D,. Transient cardiac injury during H7N9 infection. Eur J Clin Invest 2015; 45: 117-125
32. Panhwar MS, Kalra A, Gupta T,. Relation of concomitant heart failure to outcomes in patients hospitalized with influenza. Am J Cardiol 2019; 123: 1478-1480
33. Onozuka D, Hagihara A,. Extreme influenza epidemics and out-of-hospital cardiac arrest. Int J Cardiol 2018; 263: 158-162
34. Kotaka M, Kitaura Y, Deguchi H,. Experimental influenza A virus myocarditis in mice. Light and electron microscopic, virologic, and hemodynamic study. Am J Pathol 1990; 136: 409-419
35. Ray CG, Icenogle TB, Minnich LL,. The use of intravenous ribavirin to treat influenza virus-associated acute myocarditis. J Infect Dis 1989; 159: 829-836
36. Calabrese F, Carturan E, Chimenti C,. Overexpression of tumor necrosis factor (TNF)alpha and TNFalpha receptor I in human viral myocarditis: clinicopathologic correlations. Mod Pathol 2004; 17: 1108-1118
37. Davoudi AR, Maleki AR, Beykmohammadi AR,. Fulminant myopericarditis in an immunocompetent adult due to pandemic 2009 (H1N1) influenza A virus infection. Scand J Infect Dis 2012, 44: 470-472.
38. Sellers SA, Hagan RS, Hayden FG,. The hidden burden of influenza: A review of the extra-pulmonary complications of influenza infection. Influenza Other Respir Viruses 2017; 11: 372-393
39. de Jong MD, Simmons CP, Thanh TT,. Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat Med 2006; 12: 1203-1207
40. Bradley-Stewart A, Jolly L, Adamson W,. Cytokine responses in patients with mild or severe influenza A(H1N1)pdm09. J Clin Virol 2013; 58: 100-107
41. Church JA,. Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG. Pediatrics 2013; 132 (Supplement): S53-S54
42. Davey RT Jr, Lynfield R, Dwyer DE, INSIGHT FLU 002 & 003 Study Groups: The association between serum biomarkers and disease outcome in influenza A(H1N1)pdm09 virus infection: Results of two international observational cohort studies. PLoS One 2013; 8: e57121
43. Hochstadt A, Meroz Y, Landesberg G,. Myocardial dysfunction in severe sepsis and septic shock: More questions than answers? J Cardiothorac Vasc Anesth 2011; 25: 526-535
44. Kühl U, Pauschinger M, Schwimmbeck PL,. Interferon-beta treatment eliminates cardiotropic viruses and improves left ventricular function in patients with myocardial persistence of viral genomes and left ventricular dysfunction. Circulation 2003; 107: 2793-2798
45. Musher DM, Abers MS, Corrales-Medina VF,. Acute infection and myocardial infarction. N Engl J Med 2019; 380: 171-176
46. Paddock CD, Liu L, Denison AM,. Myocardial injury and bacterial pneumonia contribute to the pathogenesis of fatal influenza B virus infection. J Infect Dis 2012; 205: 895-905
47. Drosatos K, Lymperopoulos A, Kennel PJ,. Pathophysiology of sepsis-related cardiac dysfunction: driven by inflammation, energy mismanagement, or both? Curr Heart Fail Rep 2015; 12: 130-140