Anemia, micronutrient deficiencies, malaria, hemoglobinopathies and malnutrition in young children and non-pregnant women in Ghana: Findings from a national survey

PLoS ONE

Volumn 15, Issue 1, 2020, Pages

  Wegmüller, Rita ^a   Bentil, Helena ^b   Wirth, James P ^a   Petry, Nicolai ^a   Tanumihardjo, Sherry A ^c   Allen, Lindsay ^d   Williams, Thomas N ^e   Selenje, Lilian ^f   Mahama, Abraham ^f   Amoaful, Esi ^g   Steiner Asiedu, Matilda ^b   Adu Afarwuah, Seth ^b   Rohner, Fabian ^a  

^a Ground Work   (Switzerland)

^b UNIVERSITY OF GHANA   (Ghana)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d U S DEPARTMENT OF AGRICULTURE   (United States)

^e KEMRI WELLCOME TRUST RESEARCH PROGRAMME   (Kenya)

^f UNICEF   (United States)

^g GHANA HEALTH SERVICE   (Ghana)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; FERRITIN; FOLINIC ACID; OROSOMUCOID; RETINOL BINDING PROTEIN; TRACE ELEMENT;

ADOLESCENT; ADULT; AGING; ALPHA THALASSEMIA; ANEMIA; ARTICLE; BIOFORTIFICATION; CHILD; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ECONOMIC STATUS; FEMALE; GHANA; GOVERNMENT; HEMOGLOBINOPATHY; HOUSEHOLD; HUMAN; HUMAN CELL; INFANT; IRON DEFICIENCY ANEMIA; MAJOR CLINICAL STUDY; MALARIA; MALE; MALNUTRITION; MIDDLE AGED; NUTRITIONAL DEFICIENCY; OBESITY; OVERNUTRITION; PARASITEMIA; PERNICIOUS ANEMIA; PRESCHOOL CHILD; PREVALENCE; PUBLIC POLICY; QUESTIONNAIRE; RETINOL DEFICIENCY; RURAL AREA; SCHOOL CHILD; SICKLE CELL ANEMIA; SICKLE CELL TRAIT; STATISTICALLY SIGNIFICANT RESULT; STUNTING; URBAN AREA; VEIN PUNCTURE; WASTING SYNDROME; WOMEN'S HEALTH; YOUNG ADULT; HEALTH SURVEY; NUTRITIONAL DISORDER; NUTRITIONAL STATUS;

ADOLESCENT; ADULT; ANEMIA; CHILD; CHILD NUTRITION DISORDERS; CHILD, PRESCHOOL; FEMALE; GHANA; HEALTH SURVEYS; HEMOGLOBINOPATHIES; HUMANS; INFANT; MALARIA; MALE; MICRONUTRIENTS; MIDDLE AGED; NUTRITIONAL STATUS; PREVALENCE; YOUNG ADULT;

EID: 85078711239     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0228258     Document Type: Article

References (44)

1. Global Burden of Disease Study Collaborators 2013, Voss T, Barber RM, Bell B, Bertozzi-Villa A, Biryukov S, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet (London, England). Elsevier; 2015; 386: 743–800. https://doi.org/10.1016/S0140-6736(15)60692-4 PMID: 26063472
2. Stevens GA, Finucane MM, De-Regil LM, Paciorek CJ, Flaxman SR, Branca F, et al. Global, regional, and national trends in haemoglobin concentration and prevalence of total and severe anaemia in children and pregnant and non-pregnant women for 1995–2011: A systematic analysis of population-representative data. Lancet Glob Heal. 2013; https://doi.org/10.1016/S2214-109X(13)70001-9 PMID: 25103581
3. Wirth JP, Rohner F, Woodruff BA, Chiwile F, Yankson H, Koroma AS, et al. Anemia, micronutrient deficiencies, and malaria in children and women in Sierra Leone prior to the Ebola outbreak. PLoS One. 2015;
4. Kassebaum NJ, Jasrasaria R, Naghavi M, Wulf SK, Johns N, Lozano R, et al. A systematic analysis of global anemia burden from 1990 to 2010. Blood. 2014. https://doi.org/10.1182/blood-2013-06-508325 PMID: 24297872
5. Zlotkin S, Newton S, Aimone AM, Azindow I, Amenga-Etego S, Tchum K, et al. Effect of Iron Fortification on Malaria Incidence in Infants and Young Children in Ghana. JAMA. American Medical Association; 2013; 310: 938. https://doi.org/10.1001/jama.2013.277129 PMID: 24002280
6. Lartey A, Manu A, Brown KH, Dewey KG. Predictors of micronutrient status among six- to twelvemonth-old breast-fed Ghanaian infants. J Nutr. 2000/03/17. 2000; 130: 199–207. Available: http://www.ncbi.nlm.nih.gov/pubmed/10720170 https://doi.org/10.1093/jn/130.2.199 PMID: 10720170
7. Nyumuah RO, Hoang TC, Amoaful EF, Agble R, Meyer M, Wirth JP, et al. Implementing large-scale food fortification in Ghana: lessons learned. Food Nutr Bull. 2013/03/01. 2012; 33: S293–300. Available: http://www.ncbi.nlm.nih.gov/pubmed/23444710 https://doi.org/10.1177/15648265120334S305 PMID: 23444710
8. Global Alliance for Improved Nutrition, Ghana Health Service, UNICEF. National Iodine Survey Report —Ghana 2015 [Internet]. Accra, Ghana; 2017. Available: http://www.ghanahealthservice.org/downloads/Iodine_Survey_Report.pdf
9. Jones AD, Acharya Y, Galway LP. Urbanicity Gradients Are Associated with the Household- and Individual-Level Double Burden of Malnutrition in Sub-Saharan Africa. J Nutr. Oxford University Press; 2016; 146: 1257–1267. https://doi.org/10.3945/jn.115.226654 PMID: 27170726
10. University of Ghana, GroundWork, University of Wisconsin-Madison, KEMRI-Wellcome, UNICEF. Ghana Micronutrient Survey GMS 2017 [Internet]. Open Science Framework; 2017 [cited 7 Sep 2018]. https://doi.org/10.17605/OSF.IO/J7BP9
11. Ghana Statistical Services. 2010 Population & Housing Census—National Analytical Report [Internet]. 2013. Available: http://www.statsghana.gov.gh/docfiles/2010phc/National_Analytical_Report.pdf
12. Cogill B. Anthropometric Indicators Measurement Guide. 2003; Available: www.fantaproject.org
13. Erhardt JG, Estes JE, Pfeiffer CM, Biesalski HK, Craft NE. Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique. J Nutr. 2004/10/30. 2004; 134: 3127–3132. https://doi.org/10.1093/jn/134.11.3127 [pii] PMID: 15514286
14. Atkinson SH, Rockett K, Sirugo G, Bejon PA, Fulford A, O’Connell MA, et al. Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2–2 genotype. PLoS Med. 2006; 3: 652–658. https://doi.org/10.1371/journal.pmed.0030172 PMID: 16637741
15. Chong SS, Boehm CD, Higgs DR, Cutting GR. Single-tube multiplex-PCR screen for common deletional determinants of alpha-thalassemia. Blood. 2000; 95: 360–362. PMID: 10607725
16. Waterfall CM, Cobb BD. Single tube genotyping of sickle cell anaemia using PCR-based SNP analysis. Nucleic Acids Res. 2001; 29: E119. Available: /pmc/articles/PMC96713/?report = abstract https://doi.org/10.1093/nar/29.23.e119 PMID: 11726702
17. WHO Multicentre Growth Reference Study Group. WHO Child Growth Standards based on length/ height, weight and age. Acta Paediatr Suppl. 2006/07/05. 2006; 450: 76–85. Available: http://www.ncbi.nlm.nih.gov/pubmed/16817681 PMID: 16817681
18. Shetty PS, James WP. Body mass index. A measure of chronic energy deficiency in adults. FAO Food Nutr Pap. 1994/01/01. 1994; 56: 1–57. Available: http://www.ncbi.nlm.nih.gov/pubmed/7925867 PMID: 7925867
19. World Health Organization. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System (WHO/NMH/NHD/MNM/11.1) [Internet]. Geneva: World Health Organization; 2011.
20. Thurnham DI, McCabe LD, Haldar S, Wieringa FT, Northrop-Clewes CA, McCabe GP. Adjusting plasma ferritin concentrations to remove the effects of subclinical inflammation in the assessment of iron deficiency: a meta-analysis. Am J Clin Nutr. 2010/07/09. 2010; 92: 546–555. ajcn.2010.29284 [pii] https://doi.org/10.3945/ajcn.2010.29284 PMID: 20610634
21. WHO. Serum ferritin concentrations for the assessment of iron status and iron deficiency in populations. Vitamin and Mineral Nutrition Information System. Geneva, Switzerland; 2011.
22. Thurnham DI, McCabe GP, Northrop-Clewes CA, Nestel P. Effects of subclinical infection on plasma retinol concentrations and assessment of prevalence of vitamin A deficiency: meta-analysis. Lancet. 2003; 362: 2052–2058. Available: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14697804 https://doi.org/10.1016/s0140-6736(03)15099-4 PMID: 14697804
23. Tanumihardjo SA, Russell RM, Stephensen CB, Gannon BM, Craft NE, Haskell MJ, et al. Biomarkers of Nutrition for Development (BOND)—Vitamin A Review. J Nutr. Oxford University Press; 2016; 146: 1816S–1848S. https://doi.org/10.3945/jn.115.229708 PMID: 27511929
24. Allen LH, deBenoist B, Dary O, Hurrell RF, WHO, WHO/FAO. Guidelines on food fortification with micronutrients. Allen L, de Benoist B, Dary O, Hurrell R, editors. Geneva: WHO; 2006.
25. Food And Nutrition Technical Assistance. Anthropometric Indicators Measurement Guide [Internet]. 2003. Available: http://www.fantaproject.org/downloads/pdfs/anthro_2003.pdf
26. WHO/ UNICEF. Indicators for assessing infant and young child feeing practices: Part 2 Measurement. Geneva, Switzerland; 2010.
27. Filmer D, Pritchett LH. Estimating Wealth Effects Without Expenditure Data—Or Tears: An Application To Educational Enrollments In States Of India*. Demography. 2001; 38.
28. WHO/UNICEF Joint Monitoring Programme for Water Supply Sanitation and Hygiene (JMP). JMP Methodology—2017 Update & SDG Baselines [Internet]. Available: https://washdata.org/sites/default/files/documents/reports/2018-04/JMP-2017-update-methodology.pdf
29. Bartier PM, Keller CP. Multivariate interpolation to incorporate thematic surface data using inverse distance weighting (IDW). Comput Geosci. 1996; 22: 795–799. http://dx.doi.org/10.1016/0098-3004(96) 00021-0
30. WHO. Haemoglobin concentrations for the diagnosis of anaemia and assessment of severity. Vitamin and Mineral Nutrition Information System (WHO/NMH/NHD/MNM/11.1) [Internet]. Geneva: World Health Organization,; 2011. Available: http://www.who.int/vmnis/indicators/haemoglobin.pdf
31. Petry N, Olofin I, Hurrell RF, Boy E, Wirth JP, Moursi M, et al. The proportion of anemia associated with iron deficiency in low, medium, and high human development index countries: A systematic analysis of national surveys. Nutrients. 2016; 8. https://doi.org/10.3390/nu8110693 PMID: 27827838
32. Karakochuk CD, Hess SY, Moorthy D, Namaste S, Parker ME, Rappaport AI, et al. Measurement and interpretation of hemoglobin concentration in clinical and field settings: a narrative review. Annals of the New York Academy of Sciences. 2019. https://doi.org/10.1111/nyas.14003 PMID: 30652320
33. WHO. Serum retinol concentrations for determining the prevalence of vitamin A deficiency in populations. World Heal Organ. 2011; 3–7. Available: http://www.who.int/vmnis/indicators/retinol.pdf
34. Quarshie K, Amoaful E. Proceedings of the workshop on dissemination of findings of vitamin A and anaemia prevalence surveys—24–25 Nov 1998. Accra, Ghana; 1998.
35. Larson LM, Namaste SM, Williams AM, Engle-Stone R, Addo OY, Suchdev PS, et al. Adjusting retinol-binding protein concentrations for inflammation: Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project. Am J Clin Nutr. 2017; 106: 390S–401S. https://doi.org/10.3945/ajcn.116.142166 PMID: 28615251
36. Beaton GH, Martorell R, Aronson KJ, Edmonston B, McCabe G, Ross AC, et al. Effectiveness of Vitamin A Supplementation in the Control of Young Child Morbidity and Mortality in Developing Countries. ACC/SCN State-of-the-Art Series, Nutrition Policy Discussion Paper No. 13, Administrative Committee on Coordination/Subcommittee on Nutrition, United Nations. Geneva; 1993.
37. Castillo-Lancellotti C, Tur JA, Uauy R. Impact of folic acid fortification of flour on neural tube defects: a systematic review. Public Health Nutr. 2013; 16: 901–911. https://doi.org/10.1017/ S1368980012003576 PMID: 22850218
38. De-Regil LM, Peña-Rosas JP, Fernández-Gaxiola AC, Rayco-Solon P. Effects and safety of periconceptional oral folate supplementation for preventing birth defects. Cochrane Database Syst Rev. 2015; https://doi.org/10.1002/14651858.CD007950.pub3 PMID: 26662928
39. Engle-Stone R, Nankap M, Ndjebayi AO, Allen LH, Shahab-Ferdows S, Hampel D, et al. Iron, Zinc, Folate, and Vitamin B-12 Status Increased among Women and Children in Yaoundé and Douala, Cameroon, 1 Year after Introducing Fortified Wheat Flour. J Nutr. 2017; https://doi.org/10.3945/jn.116. 245076 PMID: 28592513
40. Ghana Statistical Service. Ghana Demographic and Health Survey 2014: Ghana Statistical Service, Ghana Health Service,. Ghana Statistical Service (GSS) Ghana Demographic and Health Survey. 2014. https://doi.org/10.15171/ijhpm.2016.42
41. Onyango AW, Borghi E, de Onis M, Casanovas M del C, Garza C. Complementary feeding and attained linear growth among 6–23-month-old children. Public Heal Nutr. 2013; 1–9.
42. Abarca-Gómez L, Abdeen Z, Lancet ZH-T, 2017 undefined. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement. Elsevier. Available: https://www.sciencedirect.com/science/article/pii/ S0140673617321293
43. Saydah S, Bullard KM, Cheng Y, Ali MK, Gregg EW, Geiss L, et al. Trends in cardiovascular disease risk factors by obesity level in adults in the United States, NHANES 1999–2010. Obesity. John Wiley & Sons, Ltd; 2014; 22: 1888–1895. https://doi.org/10.1002/oby.20761 PMID: 24733690
44. Global BMI Mortality Collaboration. Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents. Lancet. 2014; 766–781. https://doi.org/10.1016/S0140-6736(16)30175-1 PMID: 27423262