Scientific Opinion on the substantiation of health claims related to zeaxanthin and maintenance of normal vision (ID 1684, 2169, 2888) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

EFSA Journal

Volumn 8, Issue 10, 2010, Pages

[No Author Info available]

Author keywords

health claims; vision; Zeaxanthin

Indexed keywords

EID: 85078390813     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2010.1724     Document Type: Article

References (10)

1. Delcourt C, Carriere I, Delage M, Barberger-Gateau P and Schalch W, 2006. Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA Study. Investigative Ophthalmology and Visual Science, 47, 2329–2335.
2. Gale CR, Hall NF, Phillips DI and Martyn CN, 2003. Lutein and zeaxanthin status and risk of age-related macular degeneration. Investigative Ophthalmology and Visual Science, 44, 2461–2465.
3. Kvansakul J, Rodriguez-Carmona M, Edgar DF, Barker FM, Kopcke W, Schalch W and Barbur JL, 2006. Supplementation with the carotenoids lutein or zeaxanthin improves human visual performance. Ophthalmic and Physiological Optics, 26, 362–371.
4. Mares-Perlman JA, Brady WE, Klein R, Klein BE, Bowen P, Stacewicz-Sapuntzakis M and Palta M, 1995. Serum antioxidants and age-related macular degeneration in a population-based case-control study. Archives of Ophthalmology, 113, 1518–1523.
5. Mares-Perlman JA, Klein R, Klein BE, Greger JL, Brady WE, Palta M and Ritter LL, 1996. Association of zinc and antioxidant nutrients with age-related maculopathy. Archives of Ophthalmology, 114, 991–997.
6. Mares-Perlman JA, Fisher AI, Klein R, Palta M, Block G, Millen AE and Wright JD, 2001. Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. American Journal of Epidemiology, 153, 424–432.
7. Moeller SM, Parekh N, Tinker L, Ritenbaugh C, Blodi B, Wallace RB and Mares JA, 2006. Associations between intermediate age-related macular degeneration and lutein and zeaxanthin in the Carotenoids in Age-related Eye Disease Study (CAREDS): ancillary study of the Women's Health Initiative. Archives of Ophthalmology, 124, 1151–1162.
8. Sundelin SP and Nilsson SE, 2001. Lipofuscin-formation in retinal pigment epithelial cells is reduced by antioxidants. Free Radical Biology and Medicine, 31, 217–225.
9. Thomson LR, Toyoda Y, Langner A, Delori FC, Garnett KM, Craft N, Nichols CR, Cheng KM and Dorey CK, 2002a. Elevated retinal zeaxanthin and prevention of light-induced photoreceptor cell death in quail. Investigative Ophthalmology and Visual Science, 43, 3538–3549.
10. Thomson LR, Toyoda Y, Delori FC, Garnett KM, Wong ZY, Nichols CR, Cheng KM, Craft NE and Dorey CK, 2002b. Long term dietary supplementation with zeaxanthin reduces photoreceptor death in light-damaged Japanese quail. Experimental Eye Research, 75, 529–542.