Scientific Opinion on the substantiation of health claims related to vitamin C and protection of DNA, proteins and lipids from oxidative damage (ID 129, 138, 143, 148), antioxidant function of lutein (ID 146), maintenance of vision (ID 141, 142), collagen formation (ID 130, 131, 136, 137, 149), function of the nervous system (ID 133), function of the immune system (ID 134), function of the immune system during and after extreme physical exercise (ID 144), non-haem iron absorption (ID 132, 147), energy-yielding metabolism (ID 135), and relief in case of irritation in the upper respiratory tract (ID 1714, 1715) pursuant to Article 13(1) of Regulation (EC) No 1924/2006

EFSA Journal

Volumn 7, Issue 10, 2009, Pages

[No Author Info available]

Author keywords

collagen formation; energy metabolism; health claims; immune function; non haem iron absorption; oxidative damage; physical exercise; Vitamin C

Indexed keywords

EID: 85078378412     PISSN: None     EISSN: 18314732     Source Type: Journal    
DOI: 10.2903/j.efsa.2009.1226     Document Type: Article

References (31)

1. Badham J, Zimmermann MB, Kraemer K, 2007. The Guidebook Nutritional Anaemia. Sight and Live Press, Basel, Switzerland.
2. Bender DA, 2003. Nutritional Biochemistry of the Vitamins. Cambridge University Press, Cambridge.
3. Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C, 2008. Antioxidant supplements for prevention of mortality in healthy participants and patients with various diseases. Cochrane database of systematic reviews, issue 2.
4. Buzina-Suboticanec K, Buzina R, Stavljenic A, Farley TM, Haller J, Bergman-Markovic B, Gorajscan M, 1998. Ageing, nutritional status and immune response. Int J Vitam Nutr Res, 68, 133–141.
5. Chavance M, Herbeth B, Fournier C, Janot C, Vernhes G, 1989. Vitamin status, immunity and infections in an elderly population. Eur J Clin Nutr, 43, 827–835.
6. Chiu CJ and Taylor A, 2007. Nutritional antioxidants and age-related cataract and maculopathy. Exp Eye Res, 84, 229–45.
7. Delafuente JC, Prendergast JM, Modigh A, 1986. Immunologic modulation by vitamin C in the elderly. Int J Immunopharmacol, 8, 205–211.
8. Douglas RM, Chalker EB, Treacy B, 2000. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev (2), CD000980.
9. Douglas RM, Hemila H, D'Souza R, Chalker EB, Treacy B, 2004. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev (4), CD000980.
10. Engelhart MJ, Geerlings MI, Ruitenberg A, van Swieten JC, Hofman A, Witteman JC, Breteler MM, 2002. Dietary intake of antioxidants and risk of Alzheimer disease. JAMA, 287, 3223–3229.
11. EVM (Expert Group on Vitamins and Minerals), 2002. Revised review of vitamin C. .
12. Garrow JS, James WPT, Ralph A, 2000. Human Nutrition and Dietetics. Churchill Livingstone, London, Edinburgh.
13. Grundman M and Delaney P, 2002. Antioxidant strategies for Alzheimer's disease. Proc Nutr Soc 61, 191–202.
14. Hemila H, Douglas RM*, Chalker E, Treacy B, 2007. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev (3), CD000980.
15. Heuser G and Vojdani A, 1997. Enhancement of natural killer cell activity and T and B cell function by buffered vitamin C in patients exposed to toxic chemicals: the role of protein kinase-C. Immunopharmacol Immunotoxicol, 19, 291–312.
16. IoM (Institute of Medicine), 2000. Dietary reference intakes for vitamin C, vitamin E, selenium and carotenoids. National Academies Press, Washington DC.
17. Jacob RA, Kelley DS, Pianalto FS, Swendseid ME, Henning SM, Zhang JZ, Ames BN, Fraga CG, Peters JH, 1991. Immunocompetence and oxidant defense during ascorbate depletion of healthy men. Am J Clin Nutr, 54, 1302S–1309S.
18. Kennes B, Dumont I, Brohee D, Hubert C, Neve P, 1983. Effect of vitamin C supplements on cell-mediated immunity in old people. Gerontology, 29, 305–310.
19. Levin M, Katz A, Padayatty SJ, 2006. Vitamin C. In: Modern nutrition in health and disease. Shils ME, Shike M, Ross AC, Caballero B, Cousins RJ (Eds.). Lippincott Williams and Wilkins, Philadelphia, 507–524.
20. Meyer CH and Sekundo W, 2005. Nutritional supplementation to prevent cataract formation. Dev Ophthalmol., 38, 103–19.
21. Nieman DC, Peters EM, Henson DA, Nevines EI, Thompson MM, 2000. Influence of vitamin C supplementation on cytokine changes following an ultramarathon. J Interferon Cytokine Res, 20, 1029–1035.
22. NNR (Nordic Nutrition Recommendations), 2004. Integrating nutrition and physical activity. Nordic Council of Ministers, Copenhagen.
23. Ortega RM, Requejo AM, Andres P, Lopez-Sobaler AM, Quintas ME, Redondo MR, Navia B, Rivas T, 1997. Dietary intake and cognitive function in a group of elderly people. Am J Clin Nutr, 66, 803–809.
24. Ramakrishnan U, 2002. Prevalence of Micronutrient Malnutrition Worldwide. Nutrition Reviews, 60, Supplement 1; 46–52.
25. Sadler MJ, Strain JJ, Caballero B, 1999. Encyclopedia of human nutrition. Academic Press, San Diego.
26. Shils ME, Shike M, Ross AC, Caballero B, Cousins R, 2006. Modern Nutrition in Health and Disease. Lippincott Williams & Wilkins, Baltimore, Philadelphia.
27. Subcommittee on the Tenth Edition of the Recommended Dietary Allowances, Food and Nutrition Board, Commission on Life Sciences, National Research Council, 1989. Recommended Dietary Allowances. National Academies Press, Washington DC.
28. Tanumihardjo SA, Li J, Dosti MP, 2005. Lutein absorption is facilitated with cosupplementation of ascorbic acid in young adults. J Am Diet Assoc, 105, 114–118.
29. Tauler P, Aguilo A, Gimeno I, Noguera A, Agusti A, Tur JA, Pons A, 2003. Differential response of lymphocytes and neutrophils to high intensity physical activity and to vitamin C diet supplementation. Free Radic Res, 37, 931–938.
30. WHO (World Health Organization). 1992. The prevalence of anaemia in women: a tabulation of available information. .
31. WHO (World Health Organization). 2008. Micronutrient deficiencies. .