Differences in nicotine intake and effects from electronic and combustible cigarettes among dual users

Addiction

Volumn 115, Issue 4, 2020, Pages 757-767

  St Helen, Gideon ^a,b   Nardone, Natalie ^a,b   Addo, Newton ^a   Dempsey, Delia ^a   Havel, Christopher ^a   Jacob, Peyton ^a,b   Benowitz, Neal L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dual users; e cigarette dependence; e cigarettes; JUUL PK profile; nicotine pharmacokinetics; subjective effects

Indexed keywords

NICOTINE;

ADULT; AFFECT; BLOOD; CALIFORNIA; CRAVING; CROSSOVER PROCEDURE; ELECTRONIC CIGARETTE; FEMALE; HUMAN; MALE; PSYCHOLOGY; SMOKING; TOBACCO; WITHDRAWAL SYNDROME;

ADULT; AFFECT; CRAVING; CROSS-OVER STUDIES; ELECTRONIC NICOTINE DELIVERY SYSTEMS; FEMALE; HUMANS; MALE; NICOTINE; SAN FRANCISCO; SMOKING; SUBSTANCE WITHDRAWAL SYNDROME; TOBACCO PRODUCTS;

EID: 85077867900     PISSN: 09652140     EISSN: 13600443     Source Type: Journal    
DOI: 10.1111/add.14884     Document Type: Article

References (39)

1. Fearon I. M., Eldridge A. C., Gale N., McEwan M., Stiles M. F., Round E. K. Nicotine pharmacokinetics of electronic cigarettes: a review of the literature. Regul Toxicol Pharmacol 2018; 100: 25–34.
2. National Academies of Sciences Engineering and Medicine Public Health Consequences of e-Cigarettes. Washington, DC: National Academies of Sciences Engineering and Medicine; 2018.
3. Piper M. E., Baker T. B., Benowitz N. L., Kobinsky K., Jorenby D. E. Dual users compared to smokers: demographics, dependence, and biomarkers. Nicotine Tob Res 2019; 21: 1279–1284.
4. Nardone N., Ko J., St Helen G., Benowitz N. L. Nicotine intake, dependence, and characteristics of electronic cigarette and dual users. Tob Regul Sci 2019; 5: 27–35.
5. Robertson L., Hoek J., Blank M.-L., Richards R., Ling P., Popova L. Dual use of electronic nicotine delivery systems (ENDS) and smoked tobacco: a qualitative analysis. Tob Control 2019; 28: 13–19.
6. Hajek P., Przulj D., Phillips A., Anderson R., Mcrobbie H. Nicotine delivery to users from cigarettes and from different types of e-cigarettes. Psychopharmacology (Berl) 2017; 234: 773–779.
7. Harvanko A. M., St Helen G., Nardone N., Addo N., Benowitz N. Circadian subjective and pharmacological effects of ad libitum electronic and combustible cigarette use among dual users. Addiction 2019; In press.
8. St Helen G., Havel C., Dempsey D. A., Jacob P. III, Benowitz N. L. Nicotine delivery, retention and pharmacokinetics from various electronic cigarettes. Addiction 2016; 111: 535–544.
9. St Helen G., Dempsey D. A., Havel C. M., Jacob P. III, Benowitz N. L. Impact of e-liquid flavors on nicotine intake and pharmacology of e-cigarettes. Drug Alcohol Depend 2017; 178: 391–398.
10. Hukkanen J., Jacob P. III, Benowitz N. L. Metabolism and disposition kinetics of nicotine. Pharmacol Rev 2005; 57: 79–115.
11. Havel C. M., Benowitz N. L., Jacob P. III, St Helen G. An electronic cigarette vaping machine for the characterization of aerosol delivery and composition. Nicotine Tob Res 2017; 19: 1224–1231.
12. Heatherton T. F., Kozlowski L. T., Frecker R. C., Fagerstrom K. O. The Fagerstrom test for nicotine dependence: a revision of the Fagerstrom tolerance questionnaire. Br J Addict 1991; 86: 1119–1127.
13. Foulds J., Veldheer S., Yingst J., Hraboversusky S., Wilson S. J., Nichols T. T., et al. Development of a questionnaire for assessing dependence on electronic cigarettes among a large sample of ex-smoking E-cigarette users. Nicotine Tob Res 2015; 17: 186–192.
14. Hughes J. R., Hatsukami D. Signs and symptoms of tobacco withdrawal. Arch Gen Psychiatry 1986; 43: 289–294.
15. Becoña E., Vázquez F. L., Fuentes M. A. J., Del Carmen Lorenzo M. A. Anxiety, affect, depression and cigarette consumption. Pers Individ Differ 1998; 26: 113–119.
16. Rose J. E., Westman E. C., Behm F. M., Johnson M. P., Goldberg J. S. Blockade of smoking satisfaction using the peripheral nicotinic antagonist trimethaphan. Pharmacol Biochem Behav 1999; 62: 165–172.
17. Cox L. S., Tiffany S. T., Christen A. G. Evaluation of the brief questionnaire of smoking urges (QSU-brief) in laboratory and clinical settings. Nicotine Tob Res 2001; 3: 7–16.
18. Trehy M. L., Ye W., Hadwiger M. E., Moore T. W., Allgire J. F., Woodruff J. T., et al. Analysis of electronic cigarette cartridges, refill solutions, and smoke for nicotine and nicotine related impurities. J Liq Chromatogr Relat Technol 2011; 34: 1442–1458.
19. Jacob P. 3rd, Yu L., Wilson M., Benowitz N. L. Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: absence of an isotope effect in the clearance of (S)-nicotine-3′,3′-d2 in humans. Biol Mass Spectrom 1991; 20: 247–252.
20. Hendricks P. S., Ditre J. W., Drobes D. J., Brandon T. H. The early time course of smoking withdrawal effects. Psychopharmacology (Berl) 2006; 187: 385–396.
21. Donny E. C., Houtsmuller E., Stitzer M. L. Smoking in the absence of nicotine: behavioral, subjective and physiological effects over 11 days. Addiction 2007; 102: 324–334.
22. Perkins K. A. Sex differences in nicotine reinforcement and reward: influences on the persistence of tobacco smoking. In: Bevins R., Caggiula A. R., editors. The Motivational Impact of Nicotine and its Role in Tobacco Use. New York, NY: Springer; 2008, pp. 143–169.
23. Chiamulera C. Cue reactivity in nicotine and tobacco dependence: a ‘multiple-action' model of nicotine as a primary reinforcement and as an enhancer of the effects of smoking-associated stimuli. Brain Res Rev 2005; 48: 74–97.
24. Strasser A. A., Souprountchouk V., Kaufmann A., Blazekovic S., Leone F., Benowitz N. L., et al. Nicotine replacement, topography, and smoking phenotypes of E-cigarettes. Tob Regul Sci 2016; 2: 352–362.
25. Jorenby D. E., Smith S. S., Fiore M. C., Baker T. B. Nicotine levels, withdrawal symptoms, and smoking reduction success in real world use: a comparison of cigarette smokers and dual users of both cigarettes and E-cigarettes. Drug Alcohol Depend 2017; 170: 93–101.
26. Spindle T. R., Breland A. B., Karaoghlanian N. V., Shihadeh A. L., Eissenberg T. Preliminary results of an examination of electronic cigarette user puff topography: the effect of a mouthpiece-based topography measurement device on plasma nicotine and subjective effects. Nicotine Tob Res 2015; 17: 142–149.
27. Wagener T.L., Floyd E.L.Stepanov I., Driskill L.M., Frank S.G., Meier E. Have combustible cigarettes met their match? The nicotine delivery profiles and harmful constituent exposures of second-generation and third-generation electronic cigarette users. Tob Control 2016tobaccocontrol-2016-053041.
28. Ramôa C.P., Hiler M.M., Spindle T.R.Lopez A.A.Karaoghlanian N.Lipato T. Electronic cigarette nicotine delivery can exceed that of combustible cigarettes: a preliminary report. Tob Control 2015tobaccocontrol-2015-052447.
29. Patterson F., Benowitz N.L., Shields P., Kaufmann V., Jepson C., Wileyto P. Individual differences in nicotine intake per cigarette. Cancer Epidemiol Biomarkers Prev 2003; 12: 468–471.
30. Dawkins L. E., Kimber C. F., Doig M., Feyerabend C., Corcoran O. Self-titration by experienced e-cigarette users: blood nicotine delivery and subjective effects. Psychopharmacology (Berl) 2016; 233: 2933–2941.
31. Lee A. S., Hart J. L., Walker K. L., Keith R. J., Ridner S. L. Dual users and electronic cigarette only users: consumption and characteristics. Int J Healthc Med Sci 2018; 4: 111–116.
32. US National Cancer Institute A socioecological approach to addressing tobacco related health disparities, National Cancer Institute Tobacco Control Monograph 22. NIH Publication no. 17-CA-8035A. Bethesda, MD: US Department of Health and Human Services & National Institutes of Health; 2017.
33. Leventhal A. M., Bello M. S., Galstyan E., Higgins S. T., Barrington-Trimis J. L. Association of cumulative socioeconomic and health-related disadvantage with disparities in smoking prevalence in the United States, 2008 to 2017. JAMA Intern Med 2019; 179: 777–785.
34. Nollen N.L., Mayo M.S., Cox L.S., Benowitz N.L., Tyndale R.F., Ellerbeck E.F. Factors that explain differences in abstinence between Black and white smokers: a prospective intervention study. J Natl Cancer Inst 2019; 111: 1078–1087.
35. Nardone N., St Helen G., Addo N., Meighan S., Benowitz N. L. JUUL electronic cigarettes: nicotine exposure and the user experience. Drug Alcohol Depend 2019; 203: 83–87.
36. St.Helen G., Shahid M., Chu S., Benowitz N. L. Impact of e-liquid flavors on e-cigarette vaping behavior. Drug Alcohol Depend 2018; 189: 42–48.
37. St.Helen G., Ross K., Dempsey D., Havel C., Jacob 3rd P., Benowitz N.L. Nicotine delivery and vaping behavior during ad libitum e-cigarette access. Tob Regul Sci 2016; 2: 363–376.
38. Farsalinos K. E., Voudris V., Poulas K. E-cigarettes generate high levels of aldehydes only in ‘dry puff' conditions. Addiction 2015; 110: 1352–1356.
39. Palmer A. M., Brandon T. H. How do electronic cigarettes affect cravings to smoke or vape? Parsing the influences of nicotine and expectancies using the balanced-placebo design. J Consult Clin Psychol 2018; 86: 486–491.