Self-titration by experienced e-cigarette users: blood nicotine delivery and subjective effects

Psychopharmacology

Volumn 233, Issue 15-16, 2016, Pages 2933-2941

  Dawkins, Lynne E ^a   Kimber, Catherine F ^b   Doig, Mira ^c   Feyerabend, Colin ^c   Corcoran, Olivia ^b  

^a LONDON SOUTH BANK UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF EAST LONDON   (United Kingdom)

^c ABS Laboratories Ltd   (United Kingdom)

Author keywords

Compensation; E cigarette; Nicotine; Puffing topography; Titration

Indexed keywords

NICOTINE; NICOTINIC AGENT;

ADULT; ARTICLE; BLOOD LEVEL; ELECTRONIC CIGARETTE; FEMALE; HEALTH BELIEF; HUMAN; MALE; PRIORITY JOURNAL; SATISFACTION; SELF REPORT; SMOKING; WITHDRAWAL SYNDROME; BLOOD; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG SELF ADMINISTRATION; MIDDLE AGED; PATHOPHYSIOLOGY; TIME FACTOR; TOBACCO DEPENDENCE; VAPING; YOUNG ADULT;

ADULT; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; ELECTRONIC NICOTINE DELIVERY SYSTEMS; HUMANS; MALE; MIDDLE AGED; NICOTINE; NICOTINIC AGONISTS; SELF ADMINISTRATION; SELF REPORT; SUBSTANCE WITHDRAWAL SYNDROME; TIME FACTORS; TOBACCO USE DISORDER; VAPING; YOUNG ADULT;

EID: 84970965488     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-016-4338-2     Document Type: Article

References (32)

1. ASH [Action on Smoking and Health] (2015) ASH Fact sheet on the use of electronic cigarettes (vapourisers) among adults in Great Britain. 2015-12-10. URL:http://www.ash.org.uk/files/documents/ASH_891.pdf. Accessed: 2015-12-10. (Archived by WebCite® at http://www.webcitation.org/6dgFwr9ne).
2. Ashton H, Stepney R, Thompson JW (1979) Self-titration by cigarette smokers. BMJ 2(6186):357
3. Ashton H, Watson DW (1970) Puffing frequency and nicotine intake in cigarette smokers. Br Med J 3(5724):679–681
4. Behar RZ, Hua M, Talbot P (2015) Puffing topography and nicotine intake of electronic cigarette users. PLoS ONE 10(2):1–18
5. Brown J, Beard E, Kotz D, Michie S, West R (2014) Real-world effectiveness of e-cigarettes when used to aid smoking cessation: a cross-sectional population study. Addiction 109(9):1531–40
6. Bullen C, McRobbie H, Thornley S, Glover M, Lin R, Laugesen M (2010) Effect of an electronic nicotine delivery device (e cigarette) on desire to smoke and withdrawal, user preferences and nicotine delivery: randomised cross-over trial. Tob Control 19(2):98–103
7. Dawkins L, Corcoran O (2014) Acute electronic cigarette use: nicotine delivery and subjective effects in regular users. Psychopharmacology 231(2):401–7
8. Eissenberg T (2010) Electronic nicotine delivery devices: ineffective nicotine delivery and craving suppression after acute administration. Tob Control 19(1):87–8
9. Etter J-F (2015) Explaining the effects of electronic cigarettes on craving for tobacco in recent quitters. Drug Alcohol Depend 148:102–108, ISSN 0376–8716, http://dx.doi.org/10.1016/j.drugalcdep.2014.12.030 (0)
10. Etter J-F, Le Houezec J, Perneger TV (2003) A self-administered questionnaire to measure dependence on cigarettes: the Cigarette Dependence Scale. Neuropsychopharm 28:359–370
11. Fagerström K (2012) Determinants of tobacco use and renaming the FTND to the Fagerström Test For Cigarette Dependence. Nicotine Tob Res 14(1):75–8, PubMed PMID: 2011-30003-008
12. Farsalinos KE, Romagna G, Tsiapras D, Kyrzopoulos S, Voudris V (2013) Evaluating nicotine levels selection and patterns of electronic cigarette use in a group of “vapers” who had achieved complete substitution of smoking. Subst Abuse 7:139
13. Farsalinos KE, Spyrou A, Stefopoulos C, Tsimopoulou K, Kourkoveli P, Tsiapras D et al (2015) Nicotine absorption from electronic cigarette use: comparison between experienced consumers (vapers) and naïve users (smokers). Sci Rep 5:11269. doi:10.1038/srep11269
14. Farsalinos KE, Spyrou A, Tsimopoulou K, Stefopoulos C, Romagna G, Voudris V (2014) Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices. Sci Rep 4:4133. doi:10.1038/srep04133
15. Farsalinos, KE., Yannovits, N., Sarri, R., Voudris, V. & Poulas, K. (2016). Protocol proposal for, and evaluation of, consistency in nicotine delivery from the liquid to the aerosol of electronic cigarettes atomizers: regulatory implications. Addiction, online ahead of print. Doi: 10.1111/add.13299
16. Hua M, Yip H, Talbot P (2013) Mining data on usage of electronic nicotine delivery systems (ENDS) from YouTube videos. Tob Control 22(2):103–6
17. Kośmider L, Sobczak A, Fik M, Knysak J, Zaciera M, Kurek J, Goniewicz ML (2014) Carbonyl compounds in electronic cigarette vapors—effects of nicotine solvent and battery output voltage. Nicotine Tob Res 16(10):1319–1326
18. Lee YH, Gawron M, Goniewicz ML (2015) Changes in puffing behavior among smokers who switched from tobacco to electronic cigarettes. Addict Behav 48(0):1–4
19. Polosa R, Caponnetto P, Cibella F, Le-Houezec J (2015) Quit and smoking reduction rates in vape shop consumers: a prospective 12-month survey. Int J Environ Res Public Health 12(4):3428–3438
20. Polosa R, Morjaria JB, Caponnetto P, Campagna D, Russo C, Alamo A et al (2014) Effectiveness and tolerability of electronic cigarette in real-life: a 24-month prospective observational study. Intern Emerg Med 9(5):537–46
21. Ramôa CP, Hiler MM, Spindle TR, Lopez AA, Karaoghlanian N, Lipato T, et al. (2015). Electronic cigarette nicotine delivery can exceed that of combustible cigarettes: a preliminary report. Tob Control
22. Robinson RJ, Hensel EC, Morabito PN, Roundtree KA (2015) Electronic cigarette topography in the natural environment. PLoS ONE 10(6):1–14
23. Russell MAH (1980) Nicotine intake and its regulation. J Psychosom Res 24(5):253–64
24. Russell MAH, Jarvis MJ, Devitt G, Feyerabend C (1981) Nicotine intake by snuff users. BMJ 283(6295):814–7
25. Russell MA, Jarvis M, Iyer R, Feyerabend C (1980) Relation of nicotine yield of cigarettes to blood nicotine concentrations in smokers. Br Med J 280(6219):972–976
26. Russell MAH, Sutton SR, Iyer R, Feyerabend C, Vesey CJ (1982) Long-term switching to low-tar low-nicotine cigarettes. Br J Addict 77(2):145–58
27. Russell MA, Wilson C, Patel UA, Feyerabend C, Cole PV (1975) Plasma nicotine levels after smoking cigarettes with high, medium, and low nicotine yields. BMJ 2(5968):414–6
28. Sutton SR, Russell MAH, Iyer R, Feyerabend C, Saloojee Y (1982) Relationship between cigarette yields, puffing patterns, and smoke intake: evidence for tar compensation? BMJ 285(6342):600–3
29. Talih S, Balhas Z, Eissenberg T, Salman R, Karaoghlanian N, El Hellani A, et al. (2014) Effects of user puff topography, device voltage, and liquid nicotine concentration on electronic cigarette nicotine yield: measurements and model predictions. Nicotine Tob Res 17(2):150–157
30. Trtchounian A, Williams M, Talbot P (2010) Conventional and electronic cigarettes (e-cigarettes) have different smoking characteristics. Nicotine Tob Res 12(9):905–12
31. West R, Hajek P (2004) Evaluation of the mood and physical symptoms scale (MPSS) to assess cigarette withdrawal. Psychopharmacology 177(1/2):195–9
32. Woodward M, Tunstall‐Pedoe HU (1993) Self‐titration of nicotine: evidence from the Scottish Heart Health Study. Addiction 88(6):821–830