Distinct neural signatures detected for ADHD subtypes after controlling for micro- movements in resting state functional connectivity MRI data

Frontiers in Systems Neuroscience

Volumn , Issue DEC, 2012, Pages

  Fair, Damien A ^a   Nigg, Joel T ^a   Iyer, Swathi ^a   Bathula, Deepti ^a   Mills, Kathryn L ^a   Dosenbach, Nico U F ^b   Schlaggar, Bradley L ^b   Mennes, Maarten ^c   Gutman, David ^c   Bangaru, Saroja ^c   Buitelaar, Jan K ^d   Dickstein, Daniel P ^e   Martino, Adriana Di ^c   Kennedy, David N ^f   Kelly, Clare ^c   Luna, Beatriz ^g   Schweitzer, Julie B ^j   Velanova, Katerina ^g   Wang, Yu Feng ^m,n   Mostofsky, Stewart ^h,i   Castellanos, F Xavier ^c,k   Milham, Michael P ^k,l   more..

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY   (United States)

^c NEW YORK UNIVERSITY CHILD STUDY CENTER   (United States)

^d RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^e BROWN UNIVERSITY   (United States)

^f UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^g UNIVERSITY OF PITTSBURGH   (United States)

^h KENNEDY KRIEGER INSTITUTE   (United States)

ⁱ JOHNS HOPKINS UNIVERSITY   (United States)

^j UNIVERSITY OF CALIFORNIA   (United States)

^k NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^l CHILD MIND INSTITUTE   (United States)

^m PEKING UNIVERSITY SIXTH HOSPITAL   (China)

ⁿ PEKING UNIVERSITY   (China)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; AGE; ARTICLE; ATTENTION DEFICIT DISORDER; BOLD SIGNAL; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE CLASSIFICATION; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; INSULA; MAJOR CLINICAL STUDY; MOTOR CONTROL; NEUROMODULATION; NEUROPHYSIOLOGY; PATIENT ASSESSMENT; PREDICTION; SENSORIMOTOR FUNCTION; SUPPORT VECTOR MACHINE;

EID: 85069299344     PISSN: 16625137     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (74)

1. ADHD-200-Consortium (2012). The ADHD-200 Consortium: A Model to Advance the Translational Potential of Neuroimaging in Clinical Neuroscience. Front Syst Neurosci, 6, 62
2. Benjamini, Y., Drai, D., Elmer, G., Kafkafi, N. and Golani, I. (2001). Controlling the false discovery rate in behavior genetics research. Behav Brain Res, 125(1/2), 279-284
3. Biswal, B., Yetkin, F. Z., Haughton, V. M. and Hyde, J. S. (1995). Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med., 34(4), 537-541
4. Biswal, B. B., Mennes, M., Zuo, X. N., Gohel, S., Kelly, C., Smith, S. M., Beckmann, C. F., Adelstein, J. S., Buckner, R. L., Colcombe, S., Dogonowski, A. M., Ernst, M., Fair, D., Hampson, M., Hoptman, M. J., Hyde, J. S., Kiviniemi, V. J., Kotter, R., Li, S. J., Lin, C. P., Lowe, M. J., Mackay, C., Madden, D. J., Madsen, K. H., Margulies, D. S., Mayberg, H. S., McMahon, K., Monk, C. S., Mostofsky, S. H., Nagel, B. J., Pekar, J. J., Peltier, S. J., Petersen, S. E., Riedl, V., Rombouts, S. A., Rypma, B., Schlaggar, B. L., Schmidt, S., Seidler, R. D., Siegle, G. J., Sorg, C., Teng, G. J., Veijola, J., Villringer, A., Walter, M., Wang, L., Weng, X. C., Whitfield-Gabrieli, S., Williamson, P., Windischberger, C., Zang, Y. F., Zhang, H. Y., Castellanos, F. X. and Milham, M. P. (2010). Toward discovery science of human brain function. PNAS, 107(10), 4734-4739
5. Buckner, R. L., Andrews-Hanna, J. R. and Schacter, D. L. (2008). The brain's default network: anatomy, function, and relevance to disease. Ann N Y Acad Sci, 1124, 1-38
6. Buckner, R. L. and Carroll, D. C. (2007). Self-projection and the brain. Trends Cogn Sci, 11(2), 49-57
7. Carp, J. (2011). Optimizing the order of operations for movement scrubbing: Comment on Power et al. Neuroimage
8. Castellanos, F. X., Margulies, D. S., Kelly, A. M. C., Uddin, L. Q., Ghaffari, M., Kirsch, A., Shaw, D., Shehzad, Z., Di Martino, A., Biswal, B., Sonuga-Barke, E. J. S., Rotrosen, J., Adler, L. A. and Milham, M. P. (2008a). Cingulate-precuneus interactions: A new locus of dysfunction in adult attention-deficit/hyperactivity disorder. Biological Psychiatry, 63, 332-337
9. Castellanos, F. X., Margulies, D. S., Kelly, C., Uddin, L. Q., Ghaffari, M., Kirsch, A., Shaw, D., Shehzad, Z., Di Martino, A., Biswal, B., Sonuga-Barke, E. J., Rotrosen, J., Adler, L. A. and Milham, M. P. (2008b). Cingulate-precuneus interactions: a new locus of dysfunction in adult attention-deficit/hyperactivity disorder. Biological Psychiatry, 63(3), 332-337
10. Castellanos, F. X., Sonuga-Barke, E. J., Milham, M. P. and Tannock, R. (2006). Characterizing cognition in ADHD: beyond executive dysfunction. Trends Cogn Sci, 10(3), 117-123
11. Costa Dias, T. G., Wilson, V. B., Bathula, D., Iyer, S. P., Mills, K. L., Thurlow, B. L., Stevens, C. A., Musser, E. D., Carpenter, S. D., Grayson, D. S., Mitchell, S. H., Nigg, J. T. and Fair, D. A. (in press). Reward circuit connectivity relates to delay discounting in children with attention-deficit/hyperactivity disorder. European Neuropsychopharmacology
12. Damoiseaux, J. S., Rombouts, S. A., Barkhof, F., Scheltens, P., Stam, C. J., Smith, S. M. and Beckmann, C. F. (2006). Consistent resting-state networks across healthy subjects. PNAS, 103(37), 13848-13853
13. De Martino, F., Valente, G., Staeren, N., Ashburner, J., Goebel, R. and Formisano, E. (2008). Combining multivariate voxel selection and support vector machines for mapping and classification of fMRI spatial patterns. Neuroimage, 43(1), 44-58
14. Dosenbach, N. U., Fair, D. A., Cohen, A. L., Schlaggar, B. L. and Petersen, S. E. (2008). A dual-networks architecture of top-down control. TICS
15. Dosenbach, N. U., Fair, D. A., Miezin, F. M., Cohen, A. L., Wenger, K. K., Dosenbach, R. A. T., Fox, M. D., Snyder, A. Z., Vincent, J. L., Raichle, M. E., Schlaggar, B. L. and Petersen, S. E. (2007). Distinct brain networks for adaptive and stable task control in humans. PNAS, 104(26), 11073-11078
16. Dosenbach, N. U., Nardos, B., Cohen, A. L., Fair, D. A., Power, J. D., Church, J. A., Nelson, S. M., Wig, G. S., Vogel, A. C., Lessov-Schlaggar, C. N., Barnes, K. A., Dubis, J. W., Feczko, E., Coalson, R. S., Pruett, J. R., Jr., Barch, D. M., Petersen, S. E. and Schlaggar, B. L. (2010). Prediction of individual brain maturity using fMRI. Science, 329(5997), 1358-1361
17. Epstein, J. N., Langberg, J. M., Rosen, P. J., Graham, A., Narad, M. E., Antonini, T. N., Brinkman, W. B., Froehlich, T., Simon, J. O. and Altaye, M. (2011). Evidence for higher reaction time variability for children with ADHD on a range of cognitive tasks including reward and event rate manipulations. Neuropsychology, 25(4), 427-441
18. Fair, D. A., Bathula, D., Nikolas, M. A. and Nigg, J. T. (2012). Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in children with ADHD. PNAS, 109(17), 6769-6774
19. Fair, D. A., Cohen, A. L., Dosenbach, N. U., Church, J. A., Miezin, F. M., Barch, D. M., Raichle, M. E., Petersen, S. E. and Schlaggar, B. L. (2008). The maturing architecture of the brain's default network. PNAS, 105(10), 4028-32
20. Fair, D. A., Cohen, A. L., Power, J. D., Dosenbach, N. U., Church, J. A., Miezin, F. M., Schlaggar, B. L. and Petersen, S. E. (2009). Functional brain networks develop from a local to distributed organization. PLoS Comput Biol, 5(5), e1000381
21. Fair, D. A., Dosenbach, N. U. F., Church, J. A., Cohen, A. L., Brahmbhatt, S., Miezin, F. M., Barch, D. M., Raichle, M. E., Petersen, S. E. and Schlaggar, B. L. (2007a). Development of distinct control networks through segregation and integration. PNAS, 104(33), 13507-13512
22. Fair, D. A., Posner, J., Nagel, B. J., Bathula, D., Dias, T. G., Mills, K. L., Blythe, M. S., Giwa, A., Schmitt, C. F. and Nigg, J. T. (2010). Atypical default network connectivity in youth with attention-deficit/hyperactivity disorder. Biological Psychiatry, 68(12), 1084-1091
23. M. M. Haith & J. B. Benson (Eds.) (2008). Brain Development. Academic Press, San Diego, CA.
24. Fair, D. A., Schlaggar, B. L., Cohen, A. L., Miezin, F. M., Dosenbach, N. U., Wenger, K. K., Fox, M. D., Snyder, A. Z., Raichle, M. E. and Petersen, S. E. (2007b). A method for using blocked and event-related fMRI data to study resting state functional connectivity. Neuroimage, 35(1), 396-405
25. Fassbender, C., Zhang, H., Buzy, W. M., Cortes, C. R., Mizuiri, D., Beckett, L. and Schweitzer, J. B. (2009). A lack of default network suppression is linked to increased distractibility in ADHD. Brain Research, 1273, 114-128
26. Fox, M. D. and Raichle, M. E. (2007). Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci, 8(9), 700-711
27. Fox, M. D., Snyder, A. Z., Vincent, J. L., Corbetta, M., Van Essen, D. C. and Raichle, M. E. (2005). The human brain is intrinsically organized into dynamic, anticorrelated functional networks. PNAS, 102(27), 9673-9678
28. Fukunaga, M., Horovitz, S. G., de Zwart, J. A., van Gelderen, P., Balkin, T. J., Braun, A. R. and Duyn, J. H. (2008). Metabolic origin of BOLD signal fluctuations in the absence of stimuli. J Cereb Blood Flow and Metab, 28(7), 1377-1387
29. Fukunaga, M., Horovitz, S. G., van Gelderen, P., de Zwart, J. A., Jansma, J. M., Ikonomidou, V. N., Chu, R., Deckers, R. H., Leopold, D. A. and Duyn, J. H. (2006). Large-amplitude, spatially correlated fluctuations in BOLD fMRI signals during extended rest and early sleep stages. Magn Reson Imaging, 24(8), 979-992
30. Gilbert, D. L., Ridel, K. R., Sallee, F. R., Zhang, J., Lipps, T. D. and Wassermann, E. M. (2006). Comparison of the inhibitory and excitatory effects of ADHD medications methylphenidate and atomoxetine on motor cortex. Neuropsychopharmacology, 31(2), 442-449
31. Greicius, M. (2008). Resting-state functional connectivity in neuropsychiatric disorders. Curr Opin Neurol, 21(4), 424-430
32. Hagmann, P., Sporns, O., Madan, N., Cammoun, L., Pienaar, R., Wedeen, V. J., Meuli, R., Thiran, J. P. and Grant, P. E. (2010). White matter maturation reshapes structural connectivity in the late developing human brain. PNAS, 107(44), 19067-19072
33. Horovitz, S. G., Fukunaga, M., de Zwart, J. A., van Gelderen, P., Fulton, S. C., Balkin, T. J. and Duyn, J. H. (2008). Low frequency BOLD fluctuations during resting wakefulness and light sleep: a simultaneous EEG-fMRI study. Hum Brain Mapp, 29(6), 671-682
34. Izawa, J., Pekny, S. E., Marko, M. K., Haswell, C. C., Shadmehr, R. and Mostofsky, S. H. (2012). Motor learning relies on integrated sensory inputs in ADHD, but over-selectively on proprioception in autism spectrum conditions. Autism Res, 5(2), 124-136
35. Karrer, B., Levina, E. and Newman, M. E. (2008). Robustness of community structure in networks. Phys Rev E Stat Nonlin Soft Matter Phys, 77(4 Pt 2), 046119
36. Kelly, A. M., Di Martino, A., Uddin, L. Q., Shehzad, Z., Gee, D. G., Reiss, P. T., Margulies, D. S., Castellanos, F. X. and Milham, M. P. (2009). Development of anterior cingulate functional connectivity from late childhood to early adulthood. Cerebral Cortex, 19(3), 640-657
37. Lahey, B. B. and Willcutt, E. G. (2010). Predictive validity of a continuous alternative to nominal subtypes of attention-deficit/hyperactivity disorder for DSMV. J Clin Child Adolesc Psychol, 39(6), 761-775
38. Lancaster, J. L., Glass, T. G., Lankipalli, B. R., Downs, H., Mayberg, H. and Fox, P. T. (1995). A Modality-Independent Approach to Spatial Normalization of Tomographic Images of the Human Brain. Hum Brain Mapp, 3, 209-223
39. Leopold, D. A., Murayama, Y. and Logothetis, N. K. (2003). Very slow activity fluctuations in monkey visual cortex: implications for functional brain imaging. Cereb Cortex, 13(4), 422-433
40. Matthews, P. M., Honey, G. D. and Bullmore, E. T. (2006). Applications of fMRI in translational medicine and clinical practice. Nat Rev Neurosci, 7(9), 732-744
41. Meunier, D., Achard, S., Morcom, A. and Bullmore, E. (2009). Age-related changes in modular organization of human brain functional networks. Neuroimage, 44(3), 715-723
42. Miezin, F., Maccotta, L., Ollinger, J., Petersen, S. and Buckner, R. (2000). Characterizing the hemodynamic response: Effects of presentation rate, sampling procedure, and the possibility of ordering brain activity based on relative timing. NeuroImage, 11, 735-759
43. Mills, K. L., Bathula, D., Dias, T. G., Iyer, S. P., Fenesy, M. C., Musser, E. D., Stevens, C. A., Thurlow, B. L., Carpenter, S. D., Nagel, B. J., Nigg, J. T. and Fair, D. A. (2012). Altered cortico-striatal-thalamic connectivity in relation to spatial working memory capacity in children with ADHD. Front Psychiatry, 3, 2
44. Mostofsky, S. H., Newschaffer, C. J. and Denckla, M. B. (2003). Overflow movements predict impaired response inhibition in children with ADHD. Perceptual & Motor Skills, 97(3 Pt 2), 1315-1331
45. Mostofsky, S. H., Rimrodt, S. L., Schafer, J. G., Boyce, A., Goldberg, M. C., Pekar, J. J. and Denckla, M. B. (2006). Atypical motor and sensory cortex activation in attention-deficit/hyperactivity disorder: a functional magnetic resonance imaging study of simple sequential finger tapping. Biological Psychiatry, 59(1), 48-56
46. Mostofsky, S. H. and Simmonds, D. J. (2008). Response inhibition and response selection: two sides of the same coin. J Cogn Neurosci, 20(5), 751-761
47. Musser, E. D., Backs, R. W., Schmitt, C. F., Ablow, J. C., Measelle, J. R. and Nigg, J. T. (2011). Emotion regulation via the autonomic nervous system in children with attention-deficit/hyperactivity disorder (ADHD). J Abnorm Child Psychol, 39(6), 841-852
48. Newman, M. E. (2006). Modularity and community structure in networks. PNAS, 103(23), 8577-8582
49. Nigg, J. T. and Casey, B. J. (2005). An integrative theory of attention-deficit/ hyperactivity disorder based on the cognitive and affective neurosciences. Dev Psychopathol, 17(3), 785-806
50. Nir, Y., Hasson, U., Levy, I., Yeshurun, Y. and Malach, R. (2006). Widespread functional connectivity and fMRI fluctuations in human visual cortex in the absence of visual stimulation. Neuroimage, 30(4), 1313-1324
51. Norman, K. A., Polyn, S. M., Detre, G. J. and Haxby, J. V. (2006). Beyond mindreading: multi-voxel pattern analysis of fMRI data. Trends in Cognitive Sciences, 10(9), 424-430
52. Pennington, B. F. and Ozonoff, S. (1996). Executive functions and developmental psychopathology. J Child Psychol Psychiatry, 37(1), 51-87
53. Pereira, F., Mitchell, T. and Botvinick, M. (2009). Machine learning classifiers and fMRI: a tutorial overview. Neuroimage, 45(1 Suppl), S199-S209
54. Power, J. D., Barnes, K. A., Snyder, A. Z., Schlaggar, B. L. and Petersen, S. E. (2012a). Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage, 59(3), 2142-2154
55. Power, J. D., Barnes, K. A., Snyder, A. Z., Schlaggar, B. L. and Petersen, S. E. (2012b). Steps toward optimizing motion artifact removal in functional connectivity MRI; a reply to Carp. Neuroimage
56. Rizk-Jackson, A., Stoffers, D., Sheldon, S., Kuperman, J., Dale, A., Goldstein, J., Corey-Bloom, J., Poldrack, R. A. and Aron, A. R. Evaluating imaging biomarkers for neurodegeneration in pre-symptomatic Huntington's disease using machine learning techniques. Neuroimage
57. Rubinov, M. and Sporns, O. (2011). Weight-conserving characterization of complex functional brain networks. Neuroimage, 56(4), 2068-2079
58. Sagvolden, T., Johansen, E. B., Aase, H. and Russell, V. A. (2005). A dynamic developmental theory of attention-deficit/hyperactivity disorder (ADHD) predominantly hyperactive/impulsive and combined subtypes. Behav Brain Sci, 28(3), 397-419; discussion 419-468
59. Satterthwaite, T. D., Wolf, D. H., Loughead, J., Ruparel, K., Elliott, M. A., Hakonarson, H., Gur, R. C. and Gur, R. E. (2012). Impact of in-scanner head motion on multiple measures of functional connectivity: Relevance for studies of neurodevelopment in youth. Neuroimage, 60(1), 623-632
60. Scholvinck, M. L., Maier, A., Ye, F. Q., Duyn, J. H. and Leopold, D. A. (2010). Neural basis of global resting-state fMRI activity. PNAS, 107(22), 10238-10243
61. Shannon, B. J., Raichle, M. E., Snyder, A. Z., Fair, D. A., Mills, K. L., Zhang, D., Bache, K., Calhoun, V. D., Nigg, J. T., Nagel, B. J., Stevens, A. A. and Kiehl, K. A. (2011). Premotor functional connectivity predicts impulsivity in juvenile offenders. PNAS, 108(27), 11241-11245
62. Shaw, P., Eckstrand, K., Sharp, W., Blumenthal, J., Lerch, J. P., Greenstein, D., Clasen, L., Evans, A., Giedd, J. and Rapoport, J. L. (2007). Attentiondeficit/ hyperactivity disorder is characterized by a delay in cortical maturation. PNAS, 104(49), 19649-19654
63. Shehzad, Z., Kelly, A. M., Reiss, P. T., Gee, D. G., Gotimer, K., Uddin, L. Q., Lee, S. H., Margulies, D. S., Roy, A. K., Biswal, B. B., Petkova, E., Castellanos, F. X. and Milham, M. P. (2009). The resting brain: unconstrained yet reliable. Cerebral Cortex, 19(10), 2209-2229
64. Smyser, C. D., Inder, T. E., Shimony, J. S., Hill, J. E., Degnan, A. J., Snyder, A. Z. and Neil, J. J. (2010). Longitudinal analysis of neural network development in preterm infants. Cerebral Cortex, 20(12), 2852-2862
65. Supekar, K., Musen, M. and Menon, V. (2009). Development of large-scale functional brain networks in children. PLoS Biol, 7(7), e1000157
66. Talairach, J. and Tournoux, P. (1988). Co-Planar Stereotaxic Atlas of the Human Brain. Thieme Medical Publishers, Inc., New York.
67. van de Ven, V. G., Formisano, E., Prvulovic, D., Roeder, C. H. and Linden, D. E. (2004). Functional connectivity as revealed by spatial independent component analysis of fMRI measurements during rest. Hum Brain Mapp, 22(3), 165-178
68. Van Dijk, K. R., Hedden, T., Venkataraman, A., Evans, K. C., Lazar, S. W. and Buckner, R. L. (2010). Intrinsic functional connectivity as a tool for human connectomics: theory, properties, and optimization. Journal of Neurophysiology, 103(1), 297-321
69. Van Dijk, K. R., Sabuncu, M. R. and Buckner, R. L. (2012). The influence of head motion on intrinsic functional connectivity MRI. Neuroimage, 59(1), 431-438
70. Van Essen, D. C. (2005). A Population-Average, Landmark- and Surface-based (PALS) Atlas of Human Cerebral Cortex. Neuroimage, 28(3), 635-662
71. Van Essen, D. C., Dickson, J., Harwell, J., Hanlon, D., Anderson, C. H. and Drury, H. A. (2001). An integrated software suite for surface-based analyses of cerebral cortex. J Am Med Inform Assoc, 41, 1359-1378. See also http://brainmap.wustl.edu/caret
72. Vaurio, R. G., Simmonds, D. J. and Mostofsky, S. H. (2009). Increased intraindividual reaction time variability in attention-deficit/hyperactivity disorder across response inhibition tasks with different cognitive demands. Neuropsycholgia, 47(12), 2389-2396
73. Vincent, J. L., Patel, G. H., Fox, M. D., Snyder, A. Z., Baker, J. T., Van Essen, D. C., Zempel, J. M., Snyder, L. H., Corbetta, M. and Raichle, M. E. (2007). Intrinsic functional architecture in the anesthetized monkey brain. Nature, 447(7140), 46-47
74. Willcutt, E. G., Nigg, J. T., Pennington, B. F., Solanto, M. V., Rohde, L. A., Tannock, R., Loo, S. K., Carlson, C. L., McBurnett, K. and Lahey, B. B. (2012). Validity of DSM-IV attention deficit/hyperactivity disorder symptom dimensions and subtypes. Journal of Abnormal Psychology, 121(4), 991-1010