Managing cancer and living meaningfully (CALM): Randomised feasibility trial in patients with advanced cancer

BMJ Supportive and Palliative Care

Volumn 9, Issue 2, 2019, Pages 209-218

  Lo, Chris ^a,b   Hales, Sarah ^a,b   Chiu, Aubrey ^a   Panday, Tania ^a   Malfitano, Carmine ^a   Jung, Judy ^a   Rydall, Anne ^a   Li, Madeline ^a,b   Nissim, Rinat ^a,b   Zimmermann, Camilla ^a,b,c   Rodin, Gary ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; BAYES THEOREM; COPING BEHAVIOR; COST BENEFIT ANALYSIS; ECONOMICS; FEMALE; HUMAN; MALE; MENTAL STRESS; MIDDLE AGED; NEOPLASM; ONTARIO; PILOT STUDY; PSYCHOLOGY; QUALITY OF LIFE; SHORT TERM PSYCHOTHERAPY; STATISTICS AND NUMERICAL DATA; THERAPY;

ADAPTATION, PSYCHOLOGICAL; ADULT; AGED; BAYES THEOREM; COST-BENEFIT ANALYSIS; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; ONTARIO; PILOT PROJECTS; PSYCHOTHERAPY, BRIEF; QUALITY OF LIFE; STRESS, PSYCHOLOGICAL;

EID: 85066506758     PISSN: 2045435X     EISSN: 20454368     Source Type: Journal    
DOI: 10.1136/bmjspcare-2015-000866     Document Type: Article

References (40)

1. Li M, Boquiren VM, Lo C, et al. Depression and anxiety in supportive oncology. In: Davis M, Feyer P, Ortner P, et al, eds. Supportive oncology. Philadelphia: Elsevier, 2011:528-40.
2. Lo C, Zimmermann C, Rydall AC, et al. Longitudinal study of depressive symptoms in patients with metastatic gastrointestinal and lung cancer. J Clin Oncol 2010;28:3084-9.
3. Rodin G, Lo C, Mikulincer M, et al. Pathways to distress: the multiple determinants of depression, hopelessness, and desire for hastened death in metastatic cancer patients. Soc Sci Med 2009;68:562-9.
4. Rodin G. Individual psychotherapy for the patient with advanced disease. In: Chochinov H, Breitbart W, eds. Handbook of psychiatry in palliative medicine. London: Oxford University, 2009:443-53.
5. Spiegel D, Bloom JR, Yalom I. Group support for patients with metastatic cancer: a randomized outcome study. Arch Gen Psychiatry 1981;38:527-33.
6. Classen C, Butler LD, Koopman C, et al. Supportive-expressive group therapy and distress in patients with metastatic breast cancer: a randomized clinical intervention trial. Arch Gen Psychiatry 2001;58:494-501.
7. Bordeleau L, Szalai JP, Ennis M, et al. Quality of life in a randomized trial of group psychosocial support in metastatic breast cancer: overall effects of the intervention and an exploration of missing data. J Clin Oncol 2003;21:1944-51.
8. Kissane DW, Bloch S, Smith GC, et al. Cognitive-existential group psychotherapy for women with primary breast cancer: a randomised controlled trial. Psychooncology 2003;12:532-46.
9. Kissane DW, Love A, Hatton A, et al. Effect of cognitive-existential group therapy on survival in early-stage breast cancer. J Clin Oncol 2004;22:4255-60.
10. Breitbart W, Gibson C, Poppito SR, et al. Psychotherapeutic interventions at the end of life: a focus on meaning and spirituality. Can J Psychiatry 2004;49:366-72.
11. Applebaum AJ, Lichtenthal WG, Pessin HA, et al. Factors associated with attrition from a randomized controlled trial of meaning-centered group psychotherapy for patients with advanced cancer. Psychooncology 2012;21:1195-204.
12. Chochinov HM, Hack T, Hassard T, et al. Dignity Therapy: a novel psychotherapeutic intervention for patients near the end of life. J Clin Oncol 2005;23:5520-5.
13. Juliao M, Barbosa A, Oliveira F, et al. Efficacy of dignity therapy for depression and anxiety in terminally ill patients: early results of a randomized controlled trial. Palliat Support Care 2013;11:481-9.
14. Breitbart W, Poppito S, Rosenfeld B, et al. Pilot randomized controlled trial of individual meaning-centered psychotherapy for patients with advanced cancer. J Clin Oncol 2012;30: 1304-9.
15. Thomas LP, Meier EA, Irwin SA. Meaning-centered psychotherapy: a form of psychotherapy for patients with cancer. Curr Psychiatry Rep 2014;16:488.
16. Hales S, Lo C, Rodin G. Managing Cancer And Living Meaningfully (CALM) treatment manual: an individual psychotherapy for patients with advanced cancer. Toronto, Canada: Princess Margaret Hospital, University Health Network, (c)2010.
17. Fonagy P, Gergely G, Jurist E, et al. Affect regulation, mentalization, and the development of the self. New York: Other Press, 2002.
18. Lo C, Walsh A, Mikulincer M, et al. Measuring attachment security in patients with advanced cancer: psychometric properties of a modified and brief Experiences in Close Relationships scale. Psychooncology 2009;18:490-9.
19. Lo C, Zimmermann C, Gagliese L, et al. Sources of spiritual well-being in advanced cancer. BMJ Support Palliat Care 2011;1:149-53.
20. Kirchmann H, Steyer R, Mayer A, et al. Effects of adult inpatient group psychotherapy on attachment characteristics: an observational study comparing routine care to an untreated comparison group. Psychother Res 2012;22:95-114.
21. Lo C, Hales S, Jung J, et al.Managing Cancer And Living Meaningfully (CALM): phase 2 trial of a brief individual psychotherapy in advanced cancer. Palliat Med 2014;28:234-42.
22. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen InternMed 2001;16:606-13.
23. Katzman R, Brown T, Fuld P, et al. Validation of a short orientation-memory-concentration test of cognitive impairment. Am J Psychiatry 1983;140:734-9.
24. Nissim R, Freeman E, Lo C, et al. Managing Cancer and Living Meaningfully (CALM): a qualitative study of a brief individual psychotherapy for individuals with advanced cancer. Palliat Med 2012;26:713-21.
25. Ellis J, Lin J, Walsh A, et al. Predictors of referral for specialized psychosocial oncology care in patients with metastatic cancer: the contributions of age, distress and marital status. J Clin Oncol 2009;27:699-705.
26. Portenoy RK, Thaler HT, Kornblith AB, et al. The Memorial Symptom Assessment Scale: an instrument for the evaluation of symptom prevalence, characteristics and distress. Eur J Cancer 1994;30:1326-36.
27. First MB, Spitzer RL, Gibbon M, et al. Structured Clinical Interview for DSM-IV-TR Axis I Disorders-Patient Edition (SCID-I/P, 1/2010 revision). New York, NY: New York State Psychiatric Institute, 2010.
28. Spitzer RL, Kroenke K, Williams JB, et al. A brief measure for assessing generalized anxiety disorder: the GAD-7. Arch Intern Med 2006;166:1092-7.
29. Krause S, Rydall A, Hales S, et al. Initial validation of the Death and Dying Distress Scale for the assessment of death anxiety in advanced cancer. J Pain Symptom Manage 2015;49:126-34.
30. Peterman AH, Fitchett G, Brady MJ, et al. Measuring spiritual well-being in people with cancer: the Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale (FACIT-Sp). Ann Behav Med 2002;24:49-58.
31. Rosenberg M. Society and the adolescent self-image. Middletown, England: Wesleyan University Press, 1989.
32. Bond FW, Hayes SC, Baer RA, et al. Preliminary psychometric properties of the Acceptance and Action Questionnaire-II: a revised measure of psychological inflexibility and experiential avoidance. Behav Ther 2011;42:676-88.
33. Lo C, Burman D, Swami N, et al. Validation of the QUAL-EC for assessing quality of life in patients with advanced cancer. Eur J Cancer 2011;47:554-60.
34. Tedeschi RG, Calhoun LG. The Posttraumatic Growth Inventory: measuring the positive legacy of trauma. J Traumatic Stress 1996;9:455-71.
35. Kolden GG, Strauman TJ, Gittleman M, et al. The Therapeutic Realizations Scale-Revised (TRS-R): psychometric characteristics and relationship to treatment process and outcome. J Clin Psychol 2000;56:1207-20.
36. Hertzog MA. Considerations in determining sample size for pilot studies. Res Nurs Health 2008;31:180-91.
37. SAS Institute. SAS/STAT, version 9.3, User's Guide. Cary, NC: SAS Institute 2011.
38. Spiegelhalter DJ, Abrams KR, Myles JP. Bayesian approaches to clinical trials and health-care evaluation. Chichester, England: Wiley, 2004:49-78.
39. Gurrin LC, Kurinczuk JJ, Burton PR. Bayesian statistics in medical research: an intuitive alternative to conventiona data analysis. J Eval Clin Pract 2000;6: 193-204.
40. Akechi T, Okuyama T, Onishi J, et al. Psychotherapy for depression among incurable cancer patients. Cochrane Database Syst Rev 2008;(2):CD005537.