Managing Cancer and Living Meaningfully (CALM): Phase 2 trial of a brief individual psychotherapy for patients with advanced cancer

Palliative Medicine

Volumn 28, Issue 3, 2014, Pages 234-242

  Lo, Chris ^a,b   Hales, Sarah ^a,b   Jung, Judy ^a   Chiu, Aubrey ^a   Panday, Tania ^a   Rydall, Anne ^a   Nissim, Rinat ^a   Malfitano, Carmine ^a   Petricone Westwood, Danielle ^a   Zimmermann, Camilla ^a,b   Rodin, Gary ^a,b  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Affective symptoms; cancer; death anxiety; depression; palliative care; pilot trial; psychotherapy

Indexed keywords

AFFECTIVE SYMPTOMS; CANCER; DEATH ANXIETY; DEPRESSION; PALLIATIVE CARE; PILOT TRIAL; PSYCHOTHERAPY;

ATTITUDE TO DEATH; DEPRESSIVE DISORDER; FEASIBILITY STUDIES; FEMALE; HUMANS; INTERPERSONAL RELATIONS; MALE; MIDDLE AGED; NEOPLASMS; PALLIATIVE CARE; PILOT PROJECTS; PSYCHOTHERAPY, BRIEF; QUALITATIVE RESEARCH; REGRESSION ANALYSIS; STRESS, PSYCHOLOGICAL;

EID: 84893823056     PISSN: 02692163     EISSN: 1477030X     Source Type: Journal    
DOI: 10.1177/0269216313507757     Document Type: Article

References (57)

1. Rodin G Handbook of psychiatry in palliative medicine. Chochinov H Breitbart W, ed. London: Oxford University ; 2009: 443-453.
2. Rodin G, Lo C, Mikulincer M, et al. Pathways to distress: the multiple determinants of depression, hopelessness and the desire for hastened death in metastatic cancer patients. Soc Sci Med. 2009 ; 68: 562-569
3. Lo C, Zimmermann C, Rydall AC, et al. Longitudinal study of depressive symptoms in patients with metastatic gastrointestinal and lung cancer. J Clin Oncol. 2010 ; 28: 3084-3089
4. Lo C, Hales S, Zimmermann C, et al. Measuring death-related anxiety in advanced cancer: preliminary psychometrics of the Death and Dying Distress Scale. J Pediatr Hematol Oncol. 2011 ; 33: S140 - S145
5. Lo C, Zimmermann C, Gagliese L, et al. Sources of spiritual well-being in advanced cancer. BMJ Support Palliat Care. 2011 ; 1: 149-153
6. Rodin G, Zimmermann C. Psychoanalytic reflections on mortality: a reconsideration. J Am Acad Psychoanal Dyn Psychiatry. 2008 ; 36: 181-196 (Pubitemid 351533334)
7. Rodin G, Walsh A, Zimmermann C, et al. The contribution of attachment security and social support to depressive symptoms in patients with metastatic cancer. Psychooncology. 2007 ; 16: 1080-1091 (Pubitemid 350302530)
8. Rodin G, Zimmermann C, Rydall A, et al. The desire for hastened death in patients with metastatic cancer. J Pain Symptom Manage. 2007 ; 33: 661-665
9. Lo C, Hales S, Braun M, et al. Couples facing advanced cancer: examination of an interdependent relational system. Psychooncology. :
10. Nissim R, Gagliese L, Rodin G. The desire for hastened death in individuals with advanced cancer: a longitudinal qualitative study. Soc Sci Med. 2009 ; 69: 165-171
11. Grassi L, Indelli M, Marzola M, et al. Depressive symptoms and quality of life in home-care assisted cancer patients. J Pain Symptom Manage. 1996 ; 12: 300-307 (Pubitemid 26362304)
12. Colleoni M, Mandala M, Peruzzotto G, et al. Depression and degree of acceptance of adjuvant cytotoxic drugs. Lancet. 2000 ; 356: 1326-1327
13. Prieto JM, Blanch J, Atala J, et al. Psychiatric morbidity and impact on hospital length of stay among hematologic cancer patients receiving stem-cell transplantation. J Clin Oncol. 2002 ; 20: 1907-1917 (Pubitemid 34273283)
14. Fallowfield L, Ratcliffe D, Jenkins V, et al. Psychiatric morbidity and its recognition by doctors in patients with cancer. Br J Cancer. 2001 ; 84: 1011-1015 (Pubitemid 32448494)
15. Ellis J, Lin J, Walsh A, et al. Predictors of referral for specialized psychosocial oncology care in patients with metastatic cancer: the contributions of age, distress, and marital status. J Clin Oncol. 2009 ; 27: 699-705
16. National Institute for Health and Clinical Excellence (NICE). Cancer service guidance: supportive and palliative care. Improving supportive and palliative care for adults with cancer, http://www.nice.org.uk/CSGSP (2004, accessed 24 July 2013).
17. Turner J, Zapart S, Pedersen K, et al. Clinical practice guidelines for the psychosocial care of adults with cancer. Psychooncology. 2005 ; 14: 159-173 (Pubitemid 40403147)
18. Palmer SC, Coyne JC. Screening for depression in medical care: pitfalls, alternatives, and revised priorities. J Psychosom Res. 2003 ; 54: 279-287 (Pubitemid 38365989)
19. Ando M, Morita T, Akechi T, et al. Efficacy of short-term life-review interviews on the spiritual well-being of terminally ill cancer patients. J Pain Symptom Manage. 2010 ; 39: 993-1002
20. Chochinov HM, Kristjanson LJ, Breitbart W, et al. Effect of dignity therapy on distress and end-of-life experience in terminally ill patients: a randomised controlled trial. Lancet Oncol. 2011 ; 12: 753-762
21. LeMay K, Wilson KG. Treatment of existential distress in life threatening illness: a review of manualized interventions. Clin Psychol Rev. 2008 ; 28: 472-493 (Pubitemid 351296366)
22. Henry M, Cohen SR, Lee V, et al. The Meaning-Making intervention (MMi) appears to increase meaning in life in advanced ovarian cancer: a randomized controlled pilot study. Psychooncology. 2010 ; 19: 1340-1347
23. Akechi T, Okuyama T, Onishi J, et al. Psychotherapy for depression among incurable cancer patients. Cochrane Database Syst Rev. 2008 ; 2: CD005537
24. Barbui C, Cipriani A, Patel V, et al. Efficacy of antidepressants and benzodiazepines in minor depression: systematic review and meta-analysis. Br J Psychiatry. 2011 ; 198: 11-16
25. Canada AL, Murphy PE, Fitchett G, et al. A 3-factor model for the FACIT-Sp. Psychooncology. 2008 ; 17: 908-916
26. Block SD. Perspectives on care at the close of life. Psychological considerations, growth, and transcendence at the end of life: the art of the possible. JAMA. 2001 ; 285: 2898-2905 (Pubitemid 32537355)
27. Goodwin PJ, Leszcz M, Ennis M, et al. The effect of group psychosocial support on survival in metastatic breast cancer. N Engl J Med. 2001 ; 345: 1719-1726
28. Kissane D. Beyond the psychotherapy and survival debate: the treatment challenge of social disparity, depression and treatment adherence in psychosocial cancer care. Psychooncology. 2009 ; 18: 1-5
29. Edelman S, Bell DR, Kidman AD. A group cognitive behaviour therapy programme with metastatic breast cancer patients. Psychooncology. 1999 ; 8: 295-305 (Pubitemid 29417485)
30. Clark MM, Bostwick JM, Rummans TA. Group and individual treatment strategies for distress in cancer patients. Mayo Clin Proc. 2003 ; 78: 1538-1543 (Pubitemid 37475637)
31. Sherman AC, Pennington J, Latif U, et al. Patient preferences regarding cancer group psychotherapy interventions: a view from the inside. Psychosomatics. 2007 ; 48: 426-432 (Pubitemid 47330296)
32. Cuijpers P, Van Straten A, Warmerdam L. Are individual and group treatments equally effective in the treatment of depression in adults? A meta-analysis. Eur J Psychiatry. 2008 ; 22: 38-51
33. Hales S, Lo C, Rodin G Toronto, ON: Princess Margaret Hospital, University Health Network ; 2010 :
34. Nissim R, Freeman E, Lo C, et al. Managing Cancer And Living Meaningfully (CALM): a qualitative study of a brief individual psychotherapy for individuals with advanced cancer. Palliat Med. 2012 ; 26: 713-721
35. Luyten P, Blatt SJ, Van Houdenhove BJ, et al. Depression research and treatment: are we skating to where the puck is going to be?. Clin Psychol Rev. 2006 ; 26: 985-999 (Pubitemid 46110801)
36. Spiegel D, Bloom JR, Yalom I. Group support for patients with metastatic cancer: a randomized outcome study. Arch Gen Psychiatry. 1981 ; 38: 527-533 (Pubitemid 11121060)
37. Spiegel D, Morrow GR, Classen C, et al. Group psychotherapy for recently diagnosed breast cancer patients: a multicenter feasibility study. Psychooncology. 1999 ; 8: 482-493 (Pubitemid 30014681)
38. Classen C, Butler LD, Koopman C, et al. Supportive-expressive group therapy and distress in patients with metastatic breast cancer: a randomized clinical intervention trial. Arch Gen Psychiatry. 2001 ; 58: 494-501 (Pubitemid 32411331)
39. Giese-Davis J, Koopman C, Butler LD, et al. Change in emotion-regulation strategy for women with metastatic breast cancer following supportive-expressive group therapy. J Consult Clin Psychol. 2002 ; 70: 916-925 (Pubitemid 34847980)
40. Bordeleau L, Szalai JP, Ennis M, et al. Quality of life in a randomized trial of group psychosocial support in metastatic breast cancer: overall effects of the intervention and an exploration of missing data. J Clin Oncol. 2003 ; 21: 1944-1951 (Pubitemid 46606382)
41. Weiss JJ, Mulder CL, Antoni MH, et al. Effects of a supportive-expressive group intervention on long-term psychosocial adjustment in HIV-infected gay men. Psychother Psychosom. 2003 ; 72: 132-140 (Pubitemid 36469862)
42. Kissane DW, Bloch S, Smith GC, et al. Cognitive-existential group psychotherapy for women with primary breast cancer: a randomised controlled trial. Psychooncology. 2003 ; 12: 532-546 (Pubitemid 37086729)
43. Kissane DW, Love A, Hatton A, et al. Effect of cognitive-existential group therapy on survival in early-stage breast cancer. J Clin Oncol. 2004 ; 22: 4255-4260 (Pubitemid 41185146)
44. Breitbart W, Gibson C, Poppito SR, et al. Psychotherapeutic interventions at the end of life: a focus on meaning and spirituality. Can J Psychiatry. 2004 ; 49: 366-372 (Pubitemid 38878667)
45. Stanley K. Design of randomized controlled trials. Circulation. 2007 ; 115: 1164-1169 (Pubitemid 46673177)
46. Des Jarlais DC, Lyles C, Crepaz N, et al. Nonrandomized evaluations of behavioral and public health interventions: the TREND statement. Am J Public Health. 2004 ; 94: 361-366 (Pubitemid 38269486)
47. Mitchell SA Cambridge, MA: Harvard ; 1988 :
48. Bowlby J Attachment. New York: Basic Books ; 1982 :
49. Yalom ID Existential psychotherapy. New York: Basic Books ; 1980 :
50. Kroenke K, Spitzer RL, Williams JBW. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 ; 16: 606-613 (Pubitemid 32823891)
51. Thekkumpurath P, Walker J, Butcher I, et al. Screening for major depression in cancer outpatients: the diagnostic accuracy of the 9-item patient health questionnaire. Cancer. 2011 ; 117: 218-227
52. Lo C, Walsh A, Mikulincer M, et al. Measuring attachment security in patients with advanced cancer: psychometric properties of a modified and brief Experiences in Close Relationships scale. Psychooncology. 2009 ; 18: 490-499
53. Tedeschi RG, Calhoun LG. The Posttraumatic Growth Inventory: measuring the positive legacy of trauma. J Trauma Stress. 1996 ; 9: 455-471 (Pubitemid 126710047)
54. Stanton AL, Bower JE, Low CA Handbook of posttraumatic growth. Calhoun LG Tedeschi RG, ed. Mahwah, NJ: Lawrence Erlbaum ; 2006: 138-175.
55. Singer J. Using SAS PROC MIXED to fit multilevel models, hierarchical models, and individual growth models. J Educ Behav Stat. 1998 ; 24: 323-355 (Pubitemid 128474255)
56. Cohen J. A power primer. Psychol Bull. 1992 ; 112: 155-159
57. Hales S, Zimmermann C, Rodin G. The quality of dying and death. Arch Intern Med. 2008 ; 168: 912-918 (Pubitemid 351679630)