Acute Effects of Electronic Cigarette Inhalation on the Vasculature and the Conducting Airways

Cardiovascular Toxicology

Volumn 19, Issue 5, 2019, Pages 441-450

  Antoniewicz, Lukasz ^a   Brynedal, Amelie ^b   Hedman, Linnea ^b,c   Lundbäck, Magnus ^a   Bosson, Jenny A ^b  

^a DANDERYD HOSPITAL   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

^c LULEÅ UNIVERSITY OF TECHNOLOGY   (Sweden)

Author keywords

Arterial stiffness; Augmentation index; e Cig; Electronic cigarettes; ENDS; IOS; Pulse wave velocity

Indexed keywords

ALCOHOL; COTININE; GLYCEROL; NICOTINE; PROPYLENE GLYCOL; NICOTINIC AGENT;

ADULT; AEROSOL; ARTERIAL STIFFNESS; ARTICLE; BLOOD PRESSURE; CARDIOVASCULAR FUNCTION; CHEMICAL COMPOSITION; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; EXPOSURE; FEMALE; HEART RATE; HUMAN; HUMAN EXPERIMENT; INHALATION; LUNG FUNCTION; MALE; NORMAL HUMAN; OSCILLOMETRY; PRIORITY JOURNAL; PULSE WAVE; SPIROMETRY; VOLUNTEER; ADVERSE EVENT; AIRWAY OBSTRUCTION; AIRWAY RESISTANCE; CARDIOVASCULAR SYSTEM; DRUG EFFECT; ELECTRONIC CIGARETTE; HEMODYNAMICS; INHALATIONAL DRUG ADMINISTRATION; LUNG; PATHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; TIME FACTOR; VAPING; YOUNG ADULT;

ADMINISTRATION, INHALATION; ADULT; AEROSOLS; AIRWAY OBSTRUCTION; AIRWAY RESISTANCE; BLOOD PRESSURE; CARDIOVASCULAR SYSTEM; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; ELECTRONIC NICOTINE DELIVERY SYSTEMS; FEMALE; HEALTHY VOLUNTEERS; HEART RATE; HEMODYNAMICS; HUMANS; LUNG; MALE; NICOTINE; NICOTINIC AGONISTS; RISK ASSESSMENT; TIME FACTORS; VAPING; VASCULAR STIFFNESS; YOUNG ADULT;

EID: 85064438540     PISSN: 15307905     EISSN: 15590259     Source Type: Journal    
DOI: 10.1007/s12012-019-09516-x     Document Type: Article

References (37)

1. Lim, S. S., Vos, T., Flaxman, A. D., Danaei, G., Shibuya, K., Adair-Rohani, H., et al. (2012). A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet, 380(9859), 2224–2260. 10.1016/S0140-6736(12)61766-8.
2. WHO. (2015). WHO global report on trends in prevalence of tobacco smoking. Retrieved December 5, 2017, from http://www.who.int/tobacco/publications/surveillance/reportontrendstobaccosmoking/en/index4.html.
3. Schraufnagel, D. E., Blasi, F., Drummond, M. B., Lam, D. C., Latif, E., Rosen, M. J., et al. (2014). Electronic cigarettes. A position statement of the forum of international respiratory societies. American Journal of Respiratory and Critical Care Medicine, 190(6), 611–618. 10.1164/rccm.201407-1198pp.
4. Grana, R., Benowitz, N., & Glantz, S. A. (2014). E-cigarettes: A scientific review. Circulation, 129(19), 1972–1986. 10.1161/CIRCULATIONAHA.114.007667.
5. Wieslander, G., Norback, D., & Lindgren, T. (2001). Experimental exposure to propylene glycol mist in aviation emergency training: Acute ocular and respiratory effects. Occupational and Environmental Medicine, 58(10), 649–655. 10.1136/oem.58.10.649.
6. Lorkiewicz, P., Riggs, D. W., Keith, R. J., Conklin, D. J., Xie, Z., Sutaria, S., et al. (2018). Comparison of urinary biomarkers of exposure in humans using electronic cigarettes, combustible cigarettes, and smokeless tobacco. Nicotine & Tobacco Research. 10.1093/ntr/nty089.
7. Goniewicz, M. L., Gawron, M., Smith, D. M., Peng, M., Jacob, P., 3rd, & Benowitz, N. L. (2017). Exposure to nicotine and selected toxicants in cigarette smokers who switched to electronic cigarettes: A longitudinal within-subjects observational study. Nicotine & Tobacco Research, 19(2), 160–167. 10.1093/ntr/ntw160.
8. Carnevale, R., Sciarretta, S., Violi, F., Nocella, C., Loffredo, L., Perri, L., et al. (2016). Acute impact of tobacco versus electronic cigarette smoking on oxidative stress and vascular function. Chest, 150(3), 606–612. 10.1016/j.chest.2016.04.012.
9. Antoniewicz, L., Bosson, J. A., Kuhl, J., Abdel-Halim, S. M., Kiessling, A., Mobarrez, F., et al. (2016). Electronic cigarettes increase endothelial progenitor cells in the blood of healthy volunteers. Atherosclerosis, 255, 179–185. 10.1016/j.atherosclerosis.2016.09.064.
10. Moheimani, R. S., Bhetraratana, M., Peters, K. M., Yang, B. K., Yin, F., Gornbein, J., et al. (2017). Sympathomimetic effects of acute e-cigarette use: Role of nicotine and non-nicotine constituents. Journal of the American Heart Association, 6(9), 2. 10.1161/jaha.117.006579.
11. Chaumont, M., de Becker, B., Zaher, W., Culie, A., Deprez, G., Melot, C., et al. (2018). Differential effects of e-cigarette on microvascular endothelial function, arterial stiffness and oxidative stress: a randomized crossover trial. Scientific Reports, 8(1), 10378. 10.1038/s41598-018-28723-0.
12. Kerr, D. M. I., Brooksbank, K. J. M., Taylor, R. G., Pinel, K., Rios, F. J., Touyz, R. M., et al. (2019). Acute effects of electronic and tobacco cigarettes on vascular and respiratory function in healthy volunteers: A cross-over study. Journal of Hypertension, 37(1), 154–166. 10.1097/hjh.0000000000001890.
13. Lekakis, J., Abraham, P., Balbarini, A., Blann, A., Boulanger, C. M., Cockcroft, J., et al. (2011). Methods for evaluating endothelial function: A position statement from the European Society of Cardiology Working Group on Peripheral Circulation. European Journal of Cardiovascular Prevention and Rehabilitation, 18(6), 775–789. 10.1177/1741826711398179.
14. Vardavas, C. I., Anagnostopoulos, N., Kougias, M., Evangelopoulou, V., Connolly, G. N., & Behrakis, P. K. (2012). Short-term pulmonary effects of using an electronic cigarette: Impact on respiratory flow resistance, impedance, and exhaled nitric oxide. Chest, 141(6), 1400–1406. 10.1378/chest.11-2443.
15. Oostveen, E., MacLeod, D., Lorino, H., Farre, R., Hantos, Z., Desager, K., et al. (2003). The forced oscillation technique in clinical practice: Methodology, recommendations and future developments. European Respiratory Journal, 22(6), 1026–1041. 10.1183/09031936.03.00089403.
16. Schober, W., Szendrei, K., Matzen, W., Osiander-Fuchs, H., Heitmann, D., Schettgen, T., et al. (2014). Use of electronic cigarettes (e-cigarettes) impairs indoor air quality and increases FeNO levels of e-cigarette consumers. International Journal of Hygiene and Environmental Health, 217(6), 628–637. 10.1016/j.ijheh.2013.11.003.
17. Flouris, A. D., Chorti, M. S., Poulianiti, K. P., Jamurtas, A. Z., Kostikas, K., Tzatzarakis, M. N., et al. (2013). Acute impact of active and passive electronic cigarette smoking on serum cotinine and lung function. Inhalation Toxicology, 25(2), 91–101. 10.3109/08958378.2012.758197.
18. Hirata, K., Kawakami, M., & O’Rourke, M. F. (2006). Pulse wave analysis and pulse wave velocity: A review of blood pressure interpretation 100 years after Korotkov. Circulation Journal, 70(10), 1231–1239.
19. Miller, M. R., Hankinson, J., Brusasco, V., Burgos, F., Casaburi, R., Coates, A., et al. (2005). Standardisation of spirometry. European Respiratory Journal, 26(2), 319–338. 10.1183/09031936.05.00034805.
20. Lundback, M., Mills, N. L., Lucking, A., Barath, S., Donaldson, K., Newby, D. E., et al. (2009). Experimental exposure to diesel exhaust increases arterial stiffness in man. Particle and Fibre Toxicology, 6, 7. 10.1186/1743-8977-6-7.
21. Mitchell, G. F., Hwang, S. J., Vasan, R. S., Larson, M. G., Pencina, M. J., Hamburg, N. M., et al. (2010). Arterial stiffness and cardiovascular events: The Framingham heart study. Circulation, 121(4), 505–511. 10.1161/CIRCULATIONAHA.109.886655.
22. Franzen, K. F., Willig, J., Cayo Talavera, S., Meusel, M., Sayk, F., Reppel, M., et al. (2018). E-cigarettes and cigarettes worsen peripheral and central hemodynamics as well as arterial stiffness: A randomized, double-blinded pilot study. Vascular Medicine, 23(5), 419–425. 10.1177/1358863x18779694.
23. Lee, J., & Cooke, J. P. (2011). The role of nicotine in the pathogenesis of atherosclerosis. Atherosclerosis, 215(2), 281–283. 10.1016/j.atherosclerosis.2011.01.003.
24. Stepanov, I., Jensen, J., Hatsukami, D., & Hecht, S. S. (2008). New and traditional smokeless tobacco: Comparison of toxicant and carcinogen levels. Nicotine & Tobacco Research, 10(12), 1773–1782. 10.1080/14622200802443544.
25. Arefalk, G., Hambraeus, K., Lind, L., Michaelsson, K., Lindahl, B., & Sundstrom, J. (2014). Discontinuation of smokeless tobacco and mortality risk after myocardial infarction. Circulation, 130(4), 325–332. 10.1161/CIRCULATIONAHA.113.007252.
26. Hansson, J., Galanti, M. R., Hergens, M. P., Fredlund, P., Ahlbom, A., Alfredsson, L., et al. (2012). Use of snus and acute myocardial infarction: Pooled analysis of eight prospective observational studies. European Journal of Epidemiology, 27(10), 771–779. 10.1007/s10654-012-9704-8.
27. Hansson, J., Galanti, M. R., Hergens, M. P., Fredlund, P., Ahlbom, A., Alfredsson, L., et al. (2014). Snus (Swedish smokeless tobacco) use and risk of stroke: Pooled analyses of incidence and survival. Journal of Internal Medicine, 276(1), 87–95. 10.1111/joim.12219.
28. Carlsson, S., Andersson, T., Araghi, M., Galanti, R., Lager, A., Lundberg, M., et al. (2017). Smokeless tobacco (snus) is associated with an increased risk of type 2 diabetes: Results from five pooled cohorts. Journal of Internal Medicine, 281(4), 398–406. 10.1111/joim.12592.
29. Joseph, A. M., Norman, S. M., Ferry, L. H., Prochazka, A. V., Westman, E. C., Steele, B. G., et al. (1996). The safety of transdermal nicotine as an aid to smoking cessation in patients with cardiac disease. The New England Journal of Medicine, 335(24), 1792–1798. 10.1056/nejm199612123352402.
30. Benowitz, N. L., Porchet, H., Sheiner, L., & Jacob, P., 3rd. (1988). Nicotine absorption and cardiovascular effects with smokeless tobacco use: Comparison with cigarettes and nicotine gum. Clinical Pharmacology and Therapeutics, 44(1), 23–28.
31. Lunell, E., & Curvall, M. (2011). Nicotine delivery and subjective effects of Swedish portion snus compared with 4 mg nicotine polacrilex chewing gum. Nicotine & Tobacco Research, 13(7), 573–578. 10.1093/ntr/ntr044.
32. Wagener, T. L., Floyd, E. L., Stepanov, I., Driskill, L. M., Frank, S. G., Meier, E., et al. (2017). Have combustible cigarettes met their match? The nicotine delivery profiles and harmful constituent exposures of second-generation and third-generation electronic cigarette users. Tobacco Control, 26(e1), e23–e28. 10.1136/tobaccocontrol-2016-053041.
33. Hansson, L., Choudry, N. B., Karlsson, J. A., & Fuller, R. W. (1994). Inhaled nicotine in humans: Effect on the respiratory and cardiovascular systems. Journal of Applied Physiology, 76(6), 2420–2427.
34. Garcia-Arcos, I., Geraghty, P., Baumlin, N., Campos, M., Dabo, A. J., Jundi, B., et al. (2016). Chronic electronic cigarette exposure in mice induces features of COPD in a nicotine-dependent manner. Thorax, 71(12), 1119–1129. 10.1136/thoraxjnl-2015-208039.
35. Chaudhuri, R., Livingston, E., McMahon, A. D., Lafferty, J., Fraser, I., Spears, M., et al. (2006). Effects of smoking cessation on lung function and airway inflammation in smokers with asthma. American Journal of Respiratory and Critical Care Medicine, 174(2), 127–133. 10.1164/rccm.200510-1589OC.
36. Polosa, R., Morjaria, J., Caponnetto, P., Caruso, M., Strano, S., Battaglia, E., et al. (2014). Effect of smoking abstinence and reduction in asthmatic smokers switching to electronic cigarettes: Evidence for harm reversal. International Journal of Environmental Research and Public Health, 11(5), 4965–4977. 10.3390/ijerph110504965.
37. Cho, J. H., & Paik, S. Y. (2016). Association between electronic cigarette use and asthma among high school students in South Korea. PLoS ONE, 11(3), e0151022. 10.1371/journal.pone.0151022.