Macula densa SGLT1-NOS1-tubuloglomerular feedback pathway, a new mechanism for glomerular hyperfiltration during hyperglycemia

Journal of the American Society of Nephrology

Volumn 30, Issue 4, 2019, Pages 578-593

  Zhang, Jie ^f   Wei, Jin ^f   Jiang, Shan ^f   Xu, Lan ^a   Wang, Lei ^f   Cheng, Feng ^b   Buggs, Jacentha ^c   Koepsell, Hermann ^d   Vallon, Volker ^e   Liu, Ruisheng ^f  

^a DrexelUniversity   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c TAMPA GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF WÜRZBURG   (Germany)

^e UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^f UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; GLUCOSE; INULIN; NEURONAL NITRIC OXIDE SYNTHASE; SERINE; SODIUM GLUCOSE COTRANSPORTER 1; 3-(3-(4-(3-(GLUCOPYRANOSYLOXY)-5-ISOPROPYL-1H-PYRAZOL-4-YLMETHYL)-3-METHYLPHENOXY)PROPYLAMINO)PROPIONAMIDE; GLUCOSIDE; NITRIC OXIDE; NOS1 PROTEIN, HUMAN; NOS1 PROTEIN, MOUSE; PYRAZOLE DERIVATIVE; SLC5A1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; GLOMERULUS FILTRATION RATE; GLUCOSURIA; HYPERGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; KIDNEY CORTEX; KIDNEY TISSUE; MACULA DENSA; MALE; MOUSE; NONHUMAN; PERFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PUNCH BIOPSY; RENAL CLEARANCE; TUBULOGLOMERULAR FEEDBACK; ULTRAFILTRATION; WILD TYPE; ANIMAL; BIOSYNTHESIS; GENETICS; GLOMERULUS; HUMAN; KIDNEY DISTAL TUBULE; KNOCKOUT MOUSE; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGICAL FEEDBACK; SIGNAL TRANSDUCTION;

ANIMALS; FEEDBACK, PHYSIOLOGICAL; GLOMERULAR FILTRATION RATE; GLUCOSE; GLUCOSIDES; HUMANS; HYPERGLYCEMIA; INULIN; KIDNEY GLOMERULUS; KIDNEY TUBULES, DISTAL; MALE; MICE; MICE, KNOCKOUT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; PHOSPHORYLATION; PYRAZOLES; SIGNAL TRANSDUCTION; SODIUM-GLUCOSE TRANSPORTER 1;

EID: 85063722103     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2018080844     Document Type: Article

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