메뉴 건너뛰기




Volumn 85, Issue 3, 2019, Pages 258-265

Nanotechnological Approach to Increase the Antioxidant and Cytotoxic Efficacy of Crocin and Crocetin

Author keywords

antioxidant; Crocus sativus; cytotoxic; Iridaceae; solid lipid nanoparticles; Turbiscan analysis

Indexed keywords

CAROTENOID; CROCETIN; CROCIN; SOLID LIPID NANOPARTICLE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CYTOTOXIN; NANOPARTICLE;

EID: 85061115152     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/a-0732-5757     Document Type: Article
Times cited : (46)

References (30)
  • 1
    • 85014835420 scopus 로고    scopus 로고
    • Nanoparticles based on crocin loaded chitosan-alginate biopolymers: Antioxidant activities, bioavailability and anticancer properties
    • Rahaiee S. Hashemi M. Shojaosadati S. A. Moini S. Razavi S. H. Nanoparticles based on crocin loaded chitosan-alginate biopolymers: Antioxidant activities, bioavailability and anticancer properties. Int J Biol Macromol: 2017; 99 401 408
    • (2017) Int J Biol Macromol , vol.99 , pp. 401-408
    • Rahaiee, S.1    Hashemi, M.2    Shojaosadati, S.A.3    Moini, S.4    Razavi, S.H.5
  • 2
    • 84925839238 scopus 로고    scopus 로고
    • Evaluation of antioxidant activities of bioactive compounds and various extracts obtained from saffron (Crocus sativus L.): A review
    • Rahaiee S. Moini S. Hashemi M. Shojaosadati S. A. Evaluation of antioxidant activities of bioactive compounds and various extracts obtained from saffron (Crocus sativus L.): a review. J Food Sci Technol: 2015; 52 1881 1888
    • (2015) J Food Sci Technol , vol.52 , pp. 1881-1888
    • Rahaiee, S.1    Moini, S.2    Hashemi, M.3    Shojaosadati, S.A.4
  • 3
    • 0027184894 scopus 로고
    • Biological effects of saffron
    • Abdullaev F. I. Biological effects of saffron. Biofactors: 1993; 4 83 86
    • (1993) Biofactors , vol.4 , pp. 83-86
    • Abdullaev, F.I.1
  • 4
    • 84855851876 scopus 로고    scopus 로고
    • Crocetin: An agent derived from saffron for prevention and therapy for cancer
    • Gutheil W. G. Reed G. Ray A. Anant S. Dhar A. Crocetin: an agent derived from saffron for prevention and therapy for cancer. Curr Pharm Biotechnol: 2012; 13 173 179
    • (2012) Curr Pharm Biotechnol , vol.13 , pp. 173-179
    • Gutheil, W.G.1    Reed, G.2    Ray, A.3    Anant, S.4    Dhar, A.5
  • 6
    • 85038863025 scopus 로고    scopus 로고
    • Crocin potentiates antioxidant defense system and improves oxidative damage in liver tissue in diabetic rats
    • Yaribeygi H. Mohammadi M. T. Sahebkar A. Crocin potentiates antioxidant defense system and improves oxidative damage in liver tissue in diabetic rats. Biomed Pharmacother: 2018; 98 333 337
    • (2018) Biomed Pharmacother , vol.98 , pp. 333-337
    • Yaribeygi, H.1    Mohammadi, M.T.2    Sahebkar, A.3
  • 7
    • 85011844974 scopus 로고    scopus 로고
    • A perspective on Crocus sativus L. (saffron) constituent crocin: A potent water-soluble antioxidant and potential therapy for Alzheimer?s disease
    • Finley J. W. Gao S. A perspective on Crocus sativus L. (saffron) constituent crocin: a potent water-soluble antioxidant and potential therapy for Alzheimer?s disease. J Agric Food Chem: 2017; 65 1005 1020
    • (2017) J Agric Food Chem , vol.65 , pp. 1005-1020
    • Finley, J.W.1    Gao, S.2
  • 9
    • 85042354657 scopus 로고    scopus 로고
    • The effects of tramadol administration on hippocampal cell apoptosis, learning and memory in adult rats and neuroprotective effects of crocin
    • Baghishani F. Mohammadipour A. Hosseinzadeh H. Hosseini M. Ebrahimzadeh-Bideskan A. The effects of tramadol administration on hippocampal cell apoptosis, learning and memory in adult rats and neuroprotective effects of crocin. Metab Brain Dis: 2018; 33 907 916
    • (2018) Metab Brain Dis , vol.33 , pp. 907-916
    • Baghishani, F.1    Mohammadipour, A.2    Hosseinzadeh, H.3    Hosseini, M.4    Ebrahimzadeh-Bideskan, A.5
  • 10
    • 85047061480 scopus 로고    scopus 로고
    • Crocin alleviates myocardial ischemia/reperfusion-induced endoplasmic reticulum stress via regulation of MIR-34A/SIRT1/NRF2 pathway
    • 10.1097/SHK.0000000000001116
    • Wang X. Yuan B. Cheng B. Liu Y. Zhang B. Wang X. Lin X. Yang B. Gong G. Crocin alleviates myocardial ischemia/reperfusion-induced endoplasmic reticulum stress via regulation of MIR-34A/SIRT1/NRF2 pathway. Shock: 2018; 10.1097/SHK.0000000000001116
    • (2018) Shock
    • Wang, X.1    Yuan, B.2    Cheng, B.3    Liu, Y.4    Zhang, B.5    Wang, X.6    Lin, X.7    Yang, B.8    Gong, G.9
  • 11
    • 85018532948 scopus 로고    scopus 로고
    • Crocin reduces the inflammation response in rheumatoid arthritis
    • Li X. Jiang C. Zhu W. Crocin reduces the inflammation response in rheumatoid arthritis. Biosci Biotechnol Biochem: 2017; 81 891 898
    • (2017) Biosci Biotechnol Biochem , vol.81 , pp. 891-898
    • Li, X.1    Jiang, C.2    Zhu, W.3
  • 12
    • 85045397375 scopus 로고    scopus 로고
    • Crocin induces autophagic apoptosis in hepatocellular carcinoma by inhibiting Akt/mTOR activity
    • Yao C. Liu B. B. Qian X. D. Li L. Q. Cao H. B. Guo Q. S. Zhou G. F. Crocin induces autophagic apoptosis in hepatocellular carcinoma by inhibiting Akt/mTOR activity. Onco Targets Ther: 2018; 11 2017 2028
    • (2018) Onco Targets Ther , vol.11 , pp. 2017-2028
    • Yao, C.1    Liu, B.B.2    Qian, X.D.3    Li, L.Q.4    Cao, H.B.5    Guo, Q.S.6    Zhou, G.F.7
  • 13
    • 85042784310 scopus 로고    scopus 로고
    • Saffron carotenoids inhibit STAT3 activation and promote apoptotic progression in IL-6-stimulated liver cancer cells
    • Kim B. Park B. Saffron carotenoids inhibit STAT3 activation and promote apoptotic progression in IL-6-stimulated liver cancer cells. Oncol Rep: 2018; 39 1883 1891
    • (2018) Oncol Rep , vol.39 , pp. 1883-1891
    • Kim, B.1    Park, B.2
  • 14
    • 0642286332 scopus 로고    scopus 로고
    • Kinetic studies of saffron (Crocus sativus L.) quality deterioration
    • Tsimidou M. Biliaderis C. G. Kinetic studies of saffron (Crocus sativus L.) quality deterioration. J Agric Food Chem: 1997; 45 2890 2898
    • (1997) J Agric Food Chem , vol.45 , pp. 2890-2898
    • Tsimidou, M.1    Biliaderis, C.G.2
  • 15
    • 0001016668 scopus 로고
    • Stability of saffron pigments in aqueous extracts
    • Tsimidou M. Tsatsaroni E. Stability of saffron pigments in aqueous extracts. J Food Sci: 1993; 58 1073 1075
    • (1993) J Food Sci , vol.58 , pp. 1073-1075
    • Tsimidou, M.1    Tsatsaroni, E.2
  • 16
    • 25444434647 scopus 로고    scopus 로고
    • Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice
    • Asai A. Nakano T. Takahashi M. Nagao A. Orally administered crocetin and crocins are absorbed into blood plasma as crocetin and its glucuronide conjugates in mice. J Agric Food Chem: 2005; 53 7302 7306
    • (2005) J Agric Food Chem , vol.53 , pp. 7302-7306
    • Asai, A.1    Nakano, T.2    Takahashi, M.3    Nagao, A.4
  • 17
    • 34247890129 scopus 로고    scopus 로고
    • Crocetin, dimethylcrocetin, and safranal bind human serum albumin: Stability and antioxidative properties
    • Kanakis C. D. Tarantilis P. A. Tajmir-Riahi H. A. Polissiou M. G. Crocetin, dimethylcrocetin, and safranal bind human serum albumin: stability and antioxidative properties. J Agric Food Chem: 2007; 55 970 977
    • (2007) J Agric Food Chem , vol.55 , pp. 970-977
    • Kanakis, C.D.1    Tarantilis, P.A.2    Tajmir-Riahi, H.A.3    Polissiou, M.G.4
  • 18
    • 77949638310 scopus 로고    scopus 로고
    • Nanoemulsions as vehicles for topical administration of glycyrrhetic acid: Characterization and in vitro and in vivo evaluation
    • Puglia C. Rizza L. Drechsler M. Bonina F. Nanoemulsions as vehicles for topical administration of glycyrrhetic acid: characterization and in vitro and in vivo evaluation. Drug Deliv: 2010; 17 123 129
    • (2010) Drug Deliv , vol.17 , pp. 123-129
    • Puglia, C.1    Rizza, L.2    Drechsler, M.3    Bonina, F.4
  • 19
    • 85029626486 scopus 로고    scopus 로고
    • Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases
    • Tapeinos C. Battaglini M. Ciofani G. Advances in the design of solid lipid nanoparticles and nanostructured lipid carriers for targeting brain diseases. J Control Release: 2017; 264 306 332
    • (2017) J Control Release , vol.264 , pp. 306-332
    • Tapeinos, C.1    Battaglini, M.2    Ciofani, G.3
  • 21
    • 70849112665 scopus 로고    scopus 로고
    • Preparation of solid lipid nanoparticles from W/O/W emulsions: Preliminary studies on insulin encapsulation
    • Gallarate M. Trotta M. Battaglia L. Chirio D. Preparation of solid lipid nanoparticles from W/O/W emulsions: preliminary studies on insulin encapsulation. J Microencapsul: 2009; 26 394 402
    • (2009) J Microencapsul , vol.26 , pp. 394-402
    • Gallarate, M.1    Trotta, M.2    Battaglia, L.3    Chirio, D.4
  • 22
    • 0024594727 scopus 로고
    • Preparation of prolonged-release spherical micro-matrix of ibuprofen with acrylic polymer by the emulsion-solvent diffusion method for improving bioavailability
    • Kawashima Y. Niwa T. Handa T. Takeuchi H. Iwamoto T. Itoh Y. Preparation of prolonged-release spherical micro-matrix of ibuprofen with acrylic polymer by the emulsion-solvent diffusion method for improving bioavailability. Chem Pharm Bull: 1989; 37 425 429
    • (1989) Chem Pharm Bull , vol.37 , pp. 425-429
    • Kawashima, Y.1    Niwa, T.2    Handa, T.3    Takeuchi, H.4    Iwamoto, T.5    Itoh, Y.6
  • 24
    • 84971597385 scopus 로고    scopus 로고
    • Solid lipid nanoparticles as attractive drug vehicles: Composition, properties and therapeutic strategies
    • Geszke-Moritz M. Moritz M. Solid lipid nanoparticles as attractive drug vehicles: Composition, properties and therapeutic strategies. Mater Sci Eng C Mater Biol Appl: 2016; 68 982 994
    • (2016) Mater Sci Eng C Mater Biol Appl , vol.68 , pp. 982-994
    • Geszke-Moritz, M.1    Moritz, M.2
  • 25
    • 2542554241 scopus 로고    scopus 로고
    • Saffron can prevent chemically induced skin carcinogenesis in Swiss albino mice
    • Das I. Chakrabarty R. N. Das S. Saffron can prevent chemically induced skin carcinogenesis in Swiss albino mice. Asian Pacific J Cancer Prev: 2004; 5 70 76
    • (2004) Asian Pacific J Cancer Prev , vol.5 , pp. 70-76
    • Das, I.1    Chakrabarty, R.N.2    Das, S.3
  • 26
    • 0036377909 scopus 로고    scopus 로고
    • Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.)
    • Abdullaev F. Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.). Exp Biol Med: 2002; 227 20 25
    • (2002) Exp Biol Med , vol.227 , pp. 20-25
    • Abdullaev, F.1
  • 29
    • 67349086614 scopus 로고    scopus 로고
    • Quantification of saffron (Crocus sativus L.) metabolites crocins, picrocrocin and safranal for quality determination of the spice grown under different environmental Moroccan conditions
    • Lage M. Cantrell C. L. Quantification of saffron (Crocus sativus L.) metabolites crocins, picrocrocin and safranal for quality determination of the spice grown under different environmental Moroccan conditions. Sci Hortic: 2009; 121 366 373
    • (2009) Sci Hortic , vol.121 , pp. 366-373
    • Lage, M.1    Cantrell, C.L.2
  • 30
    • 84861634891 scopus 로고    scopus 로고
    • Curcumin loaded NLC induces histone hypoacetylation in the CNS after intraperitoneal administration in mice
    • Puglia C. Frasca G. Musumeci T. Rizza L. Puglisi G. Bonina F. Chiechio S. Curcumin loaded NLC induces histone hypoacetylation in the CNS after intraperitoneal administration in mice. Eur J Pharm Biopharm: 2012; 81 288 293
    • (2012) Eur J Pharm Biopharm , vol.81 , pp. 288-293
    • Puglia, C.1    Frasca, G.2    Musumeci, T.3    Rizza, L.4    Puglisi, G.5    Bonina, F.6    Chiechio, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.