메뉴 건너뛰기




Volumn 31, Issue 6, 2019, Pages 424-431

Evaluation of the effects of antioxidant treatment on sperm parameters and pregnancy rates in infertile patients after varicocelectomy: a randomized controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CARNITINE;

EID: 85060221553     PISSN: 09559930     EISSN: 14765489     Source Type: Journal    
DOI: 10.1038/s41443-018-0109-4     Document Type: Article
Times cited : (25)

References (36)
  • 2
    • 0025630701 scopus 로고
    • The prevalence of subfertility: a review of the current confusion and a report of two new studies
    • COI: 1:STN:280:DyaK3M%2FlvF2gug%3D%3D
    • Greenhall E, Vessey M. The prevalence of subfertility: a review of the current confusion and a report of two new studies. Fertil Steril. 1990;54:978–83.
    • (1990) Fertil Steril , vol.54 , pp. 978-983
    • Greenhall, E.1    Vessey, M.2
  • 4
    • 84861481111 scopus 로고    scopus 로고
    • Pathophysiology of varicocele in male infertility in the era of assisted reproductive technology
    • COI: 1:CAS:528:DC%2BC38XhtFSrurvK
    • Shiraishi K, Matsuyama H, Takihara H. Pathophysiology of varicocele in male infertility in the era of assisted reproductive technology. Int J Urol. 2012;19:538–50.
    • (2012) Int J Urol , vol.19 , pp. 538-550
    • Shiraishi, K.1    Matsuyama, H.2    Takihara, H.3
  • 5
    • 84871919332 scopus 로고    scopus 로고
    • Insight into oxidative stress in varicocele-associated male infertility: part 2
    • COI: 1:CAS:528:DC%2BC3sXhsFWqtA%3D%3D
    • Hamada A, Esteves SC, Agarwal A. Insight into oxidative stress in varicocele-associated male infertility: part 2. Nat Rev Urol. 2013;10:26.
    • (2013) Nat Rev Urol , vol.10 , pp. 26
    • Hamada, A.1    Esteves, S.C.2    Agarwal, A.3
  • 6
    • 34648814355 scopus 로고    scopus 로고
    • Efficacy of varicocelectomy in improving semen parameters: new meta-analytical approach
    • Agarwal A, Deepinder F, Cocuzza M, Agarwal R, Short RA, Sabanegh E, et al. Efficacy of varicocelectomy in improving semen parameters: new meta-analytical approach. Urology. 2007;70:532–8.
    • (2007) Urology , vol.70 , pp. 532-538
    • Agarwal, A.1    Deepinder, F.2    Cocuzza, M.3    Agarwal, R.4    Short, R.A.5    Sabanegh, E.6
  • 7
    • 69849090610 scopus 로고    scopus 로고
    • Microsurgical varicocelectomy for infertile men with oligospermia: differential effect of bilateral and unilateral varicocele on pregnancy outcomes
    • Baazeem A, Boman JM, Libman J, Jarvi K, Zini A. Microsurgical varicocelectomy for infertile men with oligospermia: differential effect of bilateral and unilateral varicocele on pregnancy outcomes. BJU Int. 2009;104:524–8.
    • (2009) BJU Int , vol.104 , pp. 524-528
    • Baazeem, A.1    Boman, J.M.2    Libman, J.3    Jarvi, K.4    Zini, A.5
  • 8
    • 82455208866 scopus 로고    scopus 로고
    • Are varicoceles associated with increased deoxyribonucleic acid fragmentation?
    • COI: 1:CAS:528:DC%2BC3MXhsFygu7zN
    • Zini A, Dohle G. Are varicoceles associated with increased deoxyribonucleic acid fragmentation? Fertil Steril. 2011;96:1283–7.
    • (2011) Fertil Steril , vol.96 , pp. 1283-1287
    • Zini, A.1    Dohle, G.2
  • 9
    • 84871041309 scopus 로고    scopus 로고
    • Insight into oxidative stress in varicocele-associated male infertility: part 1
    • Agarwal A, Hamada A, Esteves SC. Insight into oxidative stress in varicocele-associated male infertility: part 1. Nat Rev Urol. 2012;9:678.
    • (2012) Nat Rev Urol , vol.9 , pp. 678
    • Agarwal, A.1    Hamada, A.2    Esteves, S.C.3
  • 10
    • 84957876852 scopus 로고    scopus 로고
    • An update on the role of medical treatment including antioxidant therapy in varicocele
    • COI: 1:CAS:528:DC%2BC28XitVGlurrE
    • Garg H, Kumar R. An update on the role of medical treatment including antioxidant therapy in varicocele. Asian J Androl. 2016;18:222–8.
    • (2016) Asian J Androl , vol.18 , pp. 222-228
    • Garg, H.1    Kumar, R.2
  • 12
    • 84996848288 scopus 로고    scopus 로고
    • Sperm of patients with severe asthenozoospermia show biochemical, molecular, and genomic alterations
    • COI: 1:CAS:528:DC%2BC2sXktlajtrc%3D
    • Bonanno O, Romeo G, Asero P, Pezzino FM, Castiglione R, Burrello, et al. Sperm of patients with severe asthenozoospermia show biochemical, molecular, and genomic alterations. Reproduction. 2016;152:695–704.
    • (2016) Reproduction , vol.152 , pp. 695-704
    • Bonanno, O.1    Romeo, G.2    Asero, P.3    Pezzino, F.M.4    Castiglione, R.5    Burrello6
  • 13
    • 0347031698 scopus 로고    scopus 로고
    • The effect of zinc aspartate pretreatment on ischemia-reperfusion injury and early changes of blood and tissue antioxidant enzyme activities after unilateral testicular torsion-detorsion
    • Özkan K, Boran C, Kilinc M, Garipardic M, Kurutaş E. The effect of zinc aspartate pretreatment on ischemia-reperfusion injury and early changes of blood and tissue antioxidant enzyme activities after unilateral testicular torsion-detorsion. J Pediatr Surg. 2004;39:91–95.
    • (2004) J Pediatr Surg , vol.39 , pp. 91-95
    • Özkan, K.1    Boran, C.2    Kilinc, M.3    Garipardic, M.4    Kurutaş, E.5
  • 14
    • 0030587571 scopus 로고    scopus 로고
    • Localization of a GSH-dependent dehydroascorbate reductase in rat tissues and subcellular fractions
    • COI: 1:CAS:528:DyaK28XlslShsrw%3D
    • Paolicchi A, Pezzini A, Saviozzi M, Piaggi S, Andreuccetti M, Chieli E, et al. Localization of a GSH-dependent dehydroascorbate reductase in rat tissues and subcellular fractions. Arch Biochem Biophys. 1996;333:489–95.
    • (1996) Arch Biochem Biophys , vol.333 , pp. 489-495
    • Paolicchi, A.1    Pezzini, A.2    Saviozzi, M.3    Piaggi, S.4    Andreuccetti, M.5    Chieli, E.6
  • 15
    • 0024424663 scopus 로고
    • Investigation of detoxification capacity of rat testicular germ cells and Sertoli cells
    • COI: 1:CAS:528:DyaK3MXksVekt7s%3D
    • Yoganathan T, Eskild W, Hansson V. Investigation of detoxification capacity of rat testicular germ cells and Sertoli cells. Free Radic Biol Med. 1989;7:355–9.
    • (1989) Free Radic Biol Med , vol.7 , pp. 355-359
    • Yoganathan, T.1    Eskild, W.2    Hansson, V.3
  • 16
    • 0035155361 scopus 로고    scopus 로고
    • Effects of treatment with carnitines in infertile patients with prostato-vesiculo-epididymitis
    • COI: 1:CAS:528:DC%2BD3MXovVKitrY%3D
    • Vicari E, Calogero A. Effects of treatment with carnitines in infertile patients with prostato-vesiculo-epididymitis. Hum Reprod. 2001;16:2338–42.
    • (2001) Hum Reprod , vol.16 , pp. 2338-2342
    • Vicari, E.1    Calogero, A.2
  • 18
    • 80052260236 scopus 로고    scopus 로고
    • Varicocele and male factor infertility treatment: a new meta-analysis and review of the role of varicocele repair
    • Baazeem A, Belzile E, Ciampi A, Dohle G, Jarvi K, Salonia A, et al. Varicocele and male factor infertility treatment: a new meta-analysis and review of the role of varicocele repair. Eur Urol. 2011;60:796–808.
    • (2011) Eur Urol , vol.60 , pp. 796-808
    • Baazeem, A.1    Belzile, E.2    Ciampi, A.3    Dohle, G.4    Jarvi, K.5    Salonia, A.6
  • 19
    • 0028245550 scopus 로고
    • The relationship between total motile sperm count and the successof intrauterine insemination
    • COI: 1:STN:280:DyaK2c3ntlymuw%3D%3D
    • Brasch JG, Rawlins R, Tarchala S, Radwanska E. The relationship between total motile sperm count and the successof intrauterine insemination. Fertil Steril. 1994;62:150–4.
    • (1994) Fertil Steril , vol.62 , pp. 150-154
    • Brasch, J.G.1    Rawlins, R.2    Tarchala, S.3    Radwanska, E.4
  • 20
    • 78751515363 scopus 로고    scopus 로고
    • Attenuation of oxidative stress & DNA damage in varicocelectomy: implications in infertility management
    • PID: 21245622
    • Dada R, Shamsi MB, Venkatesh S, Gupta NP, Kumar R. Attenuation of oxidative stress & DNA damage in varicocelectomy: implications in infertility management. Indian J Med Res. 2010;132:728–30.
    • (2010) Indian J Med Res , vol.132 , pp. 728-730
    • Dada, R.1    Shamsi, M.B.2    Venkatesh, S.3    Gupta, N.P.4    Kumar, R.5
  • 21
    • 0032766456 scopus 로고    scopus 로고
    • Effect of varicocelectomy on the abnormal retention of residual cytoplasm by human spermatozoa
    • COI: 1:STN:280:DyaK1MzjtVKktg%3D%3D
    • Zini A, Buckspan M, Jamal M, Jarvi K. Effect of varicocelectomy on the abnormal retention of residual cytoplasm by human spermatozoa. Hum Reprod. 1999;14:1791–3.
    • (1999) Hum Reprod , vol.14 , pp. 1791-1793
    • Zini, A.1    Buckspan, M.2    Jamal, M.3    Jarvi, K.4
  • 23
    • 85042694375 scopus 로고    scopus 로고
    • Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: A double-blind placebo-controlled study
    • Busetto GM, Agarwal A, Virmani A, Antonini G, Ragonesi G, Del Giudice F et al. Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study. Andrologia 2018; 50: 10.1111/and.12927.
    • (2018) Andrologia , vol.50 , Issue.3
    • Busetto, G.M.1    Agarwal, A.2    Virmani, A.3    Antonini, G.4    Ragonesi, G.5    Del Giudice, F.6    Micic, S.7    Gentile, V.8    De Berardinis, E.9
  • 24
    • 85033729596 scopus 로고    scopus 로고
    • The effect of saffron on semen analysis in infertile men with clinical varicocele after varicocelectomy
    • Badr YAA, Sepehran E, Del Azar A, Sadeghi H, Nouri M. The effect of saffron on semen analysis in infertile men with clinical varicocele after varicocelectomy. Nephro-Urology Monthly 2017; 9:e59939.
    • (2017) Nephro-Urology Monthly , vol.9
    • Badr, Y.A.A.1    Sepehran, E.2    Del Azar, A.3    Sadeghi, H.4    Nouri, M.5
  • 25
    • 85046545997 scopus 로고    scopus 로고
    • Melatonin therapy adds extra benefit to varicecelectomy in terms of sperm parameters, hormonal profile and total antioxidant capacity: A placebo-controlled, double-blind trial
    • Lu XL, Liu JJ, Li JT, Yang QA, Zhang JM. Melatonin therapy adds extra benefit to varicecelectomy in terms of sperm parameters, hormonal profile and total antioxidant capacity: a placebo-controlled, double-blind trial. Andrologia 2018;50:e13033.
    • (2018) Andrologia , vol.50 , Issue.6
    • Lu, X.-L.1    Liu, J.-J.2    Li, J.-T.3    Yang, Q.-A.4    Zhang, J.-M.5
  • 26
    • 84964792155 scopus 로고    scopus 로고
    • A preliminary study: N-acetyl-L-cysteine improves semen quality following varicocelectomy
    • COI: 1:CAS:528:DC%2BC2sXmsleku74%3D, PID: 27123209
    • Barekat F, Tavalaee M, Deemeh MR, Bahreinian M, Azadi L, Abbasi H, et al. A preliminary study: N-acetyl-L-cysteine improves semen quality following varicocelectomy. Int J Fertil Steril. 2016;10:120–6.
    • (2016) Int J Fertil Steril , vol.10 , pp. 120-126
    • Barekat, F.1    Tavalaee, M.2    Deemeh, M.R.3    Bahreinian, M.4    Azadi, L.5    Abbasi, H.6
  • 27
    • 85050743919 scopus 로고    scopus 로고
    • Effect of adjuvant drug therapy after varicocelectomy on fertility outcome in males with varicocele-associated infertility: systematic review and meta-analysis
    • Chen YW, Niu YH, Wang DQ, Li H, Pokhrel G, Xu H, et al. Effect of adjuvant drug therapy after varicocelectomy on fertility outcome in males with varicocele-associated infertility: systematic review and meta-analysis. Andrologia. 2018;50:e13070.
    • (2018) Andrologia , vol.50
    • Chen, Y.W.1    Niu, Y.H.2    Wang, D.Q.3    Li, H.4    Pokhrel, G.5    Xu, H.6
  • 28
    • 84963818716 scopus 로고    scopus 로고
    • Comparison of the effects of varicocelectomy and oral L-carnitine on sperm parameters in infertile men with varicocele
    • COI: 1:CAS:528:DC%2BC2sXivVWht74%3D, PID: 27190879
    • Sofimajidpour H, Ghaderi E, Ganji O. Comparison of the effects of varicocelectomy and oral L-carnitine on sperm parameters in infertile men with varicocele. J Clin Diagn Res. 2016;10:PC07–10.
    • (2016) J Clin Diagn Res , vol.10 , pp. PC07-PC10
    • Sofimajidpour, H.1    Ghaderi, E.2    Ganji, O.3
  • 29
    • 33646093473 scopus 로고    scopus 로고
    • Carnitine for the treatment of idiopathic asthenospermia: a randomized, double-blind, placebo-controlled trial
    • Sigman M, Glass S, Campagnone J, Pryor JL. Carnitine for the treatment of idiopathic asthenospermia: a randomized, double-blind, placebo-controlled trial. Fertil Steril. 2006;85:1409–14.
    • (2006) Fertil Steril , vol.85 , pp. 1409-1414
    • Sigman, M.1    Glass, S.2    Campagnone, J.3    Pryor, J.L.4
  • 30
    • 2942571547 scopus 로고    scopus 로고
    • A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia
    • COI: 1:CAS:528:DC%2BD2MXitFCrtbs%3D
    • Lenzi A, Sgro P, Salacone P, Paoli D, Gilio B, Lombardo F, et al. A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia. Fertil Steril. 2004;81:1578–84.
    • (2004) Fertil Steril , vol.81 , pp. 1578-1584
    • Lenzi, A.1    Sgro, P.2    Salacone, P.3    Paoli, D.4    Gilio, B.5    Lombardo, F.6
  • 31
    • 84924356828 scopus 로고    scopus 로고
    • Coenzyme Q10 supplementation in infertile men with low-grade varicocele: an open, uncontrolled pilot study
    • COI: 1:CAS:528:DC%2BC2cXhtlymsLvI
    • Festa R, Giacchi E, Raimondo S, Tiano L, Zuccarelli P, Silvestrini A, et al. Coenzyme Q10 supplementation in infertile men with low-grade varicocele: an open, uncontrolled pilot study. Andrologia. 2014;46:805–7.
    • (2014) Andrologia , vol.46 , pp. 805-807
    • Festa, R.1    Giacchi, E.2    Raimondo, S.3    Tiano, L.4    Zuccarelli, P.5    Silvestrini, A.6
  • 32
    • 84855507529 scopus 로고    scopus 로고
    • Coenzyme Q10 improves seminal oxidative defense but does not affect on semen parameters in idiopathic oligoasthenoteratozoospermia: a randomized double-blind, placebo controlled trial
    • COI: 1:CAS:528:DC%2BC38XmsVOrtA%3D%3D, PID: 21399391
    • Nadjarzadeh A, Sadeghi M, Amirjannati N, Vafa M, Motevalian S, Gohari M, et al. Coenzyme Q10 improves seminal oxidative defense but does not affect on semen parameters in idiopathic oligoasthenoteratozoospermia: a randomized double-blind, placebo controlled trial. J Endocrinol Invest. 2011;34:e224–e228.
    • (2011) J Endocrinol Invest , vol.34 , pp. e224-e228
    • Nadjarzadeh, A.1    Sadeghi, M.2    Amirjannati, N.3    Vafa, M.4    Motevalian, S.5    Gohari, M.6
  • 33
    • 84945177537 scopus 로고    scopus 로고
    • Analysis of the correlation between sperm DNA integrity and conventional semen parameters in infertile men
    • Aydos OS, Yükselten Y, Kaplan F, Sunguroğlu A, Aydos K. Analysis of the correlation between sperm DNA integrity and conventional semen parameters in infertile men. Turk J Urol. 2015;41:191.
    • (2015) Turk J Urol , vol.41 , pp. 191
    • Aydos, O.S.1    Yükselten, Y.2    Kaplan, F.3    Sunguroğlu, A.4    Aydos, K.5
  • 34
    • 0036720422 scopus 로고    scopus 로고
    • Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase
    • COI: 1:CAS:528:DC%2BD38XmsV2jtro%3D
    • Foresta C, Flohé L, Garolla A, Roveri A, Ursini F, Maiorino M. Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase. Biol Reprod. 2002;67:967–71.
    • (2002) Biol Reprod , vol.67 , pp. 967-971
    • Foresta, C.1    Flohé, L.2    Garolla, A.3    Roveri, A.4    Ursini, F.5    Maiorino, M.6
  • 35
    • 84888299059 scopus 로고    scopus 로고
    • The role of nutraceuticals in male fertility
    • Ko EY, Sabanegh ES. The role of nutraceuticals in male fertility. Urol Clin North Am. 2014;41:181–93.
    • (2014) Urol Clin North Am , vol.41 , pp. 181-193
    • Ko, E.Y.1    Sabanegh, E.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.